这项研究旨在回答根据PICO策略制定的问题:“哪些精油对牙科丙烯酸树脂上形成的生物膜具有抗菌活性?”干预(精油的应用),比较(义齿清洁剂,抗真菌药物,氯己定,和口腔漱口水),和结果(抗生物膜活性)。包括评估EOs对丙烯酸树脂上形成的生物膜的活性的体外实验研究。遵循PRISMA准则,搜索是在PubMed中进行的,科学直接,Embase,和Lilacs数据库以及2023年12月使用GoogleScholar和ProQuest的灰色文献。对所包括的主要研究的参考列表进行手动搜索。在确定的1467篇文章中,选择了37名进行全文阅读,并包括12名。评估了12个EO,其中11对念珠菌具有活性。,3针对金黄色葡萄球菌,和1针对铜绿假单胞菌。Cymboponcitratus的EOS,浙青,和Cymboponnardus表现出比氯己定更高的作用,C.比李斯特林更高的叙述,citratus高于制霉菌素,而互叶千层高于氟康唑和制霉菌素。然而,洗必泰比西度和丹参更有效,次氯酸钠比L.sidoides更有效,制霉菌素比生姜更有效,两性霉素B比球桉树和互叶互叶分枝杆菌更有效。总之,zeylanicumC.的EO,C.citratus,C.Nardus,和互花假丝酵母显示出抗菌活性,以减少牙科丙烯酸树脂上的生物膜。
This study aimed to answer the question formulated according to the PICO strategy: \'Which essential oils show antimicrobial activity against biofilms formed on dental acrylic resin?\' composed by population (dental acrylic resin), intervention (application of essential oils), comparison (denture cleansers, antifungal drugs, chlorhexidine, and oral mouthwashes), and outcome (antibiofilm activity). In vitro experimental studies evaluating the activity of EOs on biofilm formed on acrylic resin were included. PRISMA guidelines were followed, and the search was performed in the PubMed, Science Direct, Embase, and Lilacs databases and in the gray literature using Google Scholar and ProQuest in December 2023. A manual search of the reference lists of the included primary studies was performed. Of the 1467 articles identified, 37 were selected for full-text reading and 12 were included. Twelve EOs were evaluated, of which 11 showed activity against Candida spp., 3 against Staphylococcus aureus, and 1 against Pseudomonas aeruginosa. The EOs of Cymbopogon citratus, Cinnamomum zeylanicum, and Cymbopogon nardus showed higher action than chlorhexidine, C. nardus higher than Listerine, C. citratus higher than
nystatin, and Melaleuca alternifolia higher than fluconazole and
nystatin. However, chlorhexidine was more effective than Lippia sidoides and Salvia officinalis, sodium hypochlorite was more effective than L. sidoides,
nystatin was more effective than Zingiber officinale, Amphotericin B more effective than Eucalyptus globulus and M. alternifolia. In conclusion, the EOs of C. zeylanicum, C. citratus, C. nardus, and M. alternifolia showed antimicrobial activity to reduce biofilm on dental acrylic resin.