Operative time

手术时间
  • 文章类型: Journal Article
    背景:脊髓肿瘤的微创治疗很常见。这项研究的目的是比较经微内镜微创手术-通过自制管状牵开器(MIS-TR)和显微全椎板切除术(开放手术)治疗的胸髓外脊柱肿瘤(TEST)患者的围手术期结果。
    方法:2016年2月至2021年2月,纳入了51例TEST患者。根据他们的临床数据,将患者分为MIS-TR组(n=30)和开放手术组(n=21)并进行评估.
    结果:在两组中,平均手术时间,围手术期ASIA评分的变化,和改良的Macnab评分具有可比性。MIS-TR组术后平均住院时间明显短于开放手术组(p<0.0001)。MIS-TR组的平均失血量明显低于开放手术组(p=0.001)。MIS-TR组围手术期并发症发生率明显低于开放手术组(p<0.0001)。在3个月的随访中,两组间Oswestry残疾指数(ODI)评分改善无显著差异.尽管如此,在12个月的随访中,MIS-TR组的平均ODI显著低于开放手术组(p=0.023).术后完全恢复的主要影响因素为术前ASIA评分(OR7.848,P=0.002),手术并发症(OR0.017,P=0.008)和年龄(OR0.974,P=0.393)。
    结论:MIS-TR比开放手术治疗TEST更安全有效,但MIS-TR的长期恢复并不比开放手术好。
    BACKGROUND: Minimally invasive treatments for spinal cord tumours are common. The aim of this study was to compare the perioperative outcomes of patients with thoracic extramedullary spinal tumours (TEST) treated by microendoscopic minimally invasive surgery-hemilaminectomy through a homemade tubular retractor (MIS-TR) and microscopic full laminectomy (open surgery).
    METHODS: Between February 2016 and February 2021, 51 patients with TEST were included. According to their clinical data, patients were classified into the MIS-TR group (n = 30) and the open surgery group (n = 21) and assessed.
    RESULTS: In both groups, the mean operation time, change in perioperative ASIA score, and modified Macnab score were comparable. The average postoperative hospital stay in the MIS-TR group was substantially shorter than that in the open surgery group (p < 0.0001). The mean blood loss volume in the MIS-TR group was substantially lower than that in the open surgery group (p = 0.001). The perioperative complication rate in the MIS-TR group was considerably lower than that in the open surgery group (p < 0.0001). At the 3-month follow-up, there was no substantial difference in the Oswestry Disability Index (ODI) score improvement between the two groups. Nonetheless, at the 12-month follow-up, the average ODI in the MIS-TR group was considerably lower than that in the open surgery group (p = 0.023). The main influencing factors for complete postoperative recovery were preoperative ASIA score (OR 7.848, P = 0.002), surgical complications (OR 0.017, P = 0.008) and age (OR 0.974, P = 0.393).
    CONCLUSIONS: MIS-TR is safer and more effective than open surgery for treating TEST, but the long-term recovery of MIS-TR is not better than that of open surgery.
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  • 文章类型: Journal Article
    背景:髓内钉(IMN)和钢板内固定是胫骨远端骨折最常用的手术方式。然而,它们在功能结局和并发症方面的疗效优势仍存在争议.这里,我们进行了系统评价和荟萃分析,以比较这两种模式的疗效.
    方法:在PubMed,WebofScience,EMBASE,ClinicalTrials.gov,和Cochrane图书馆至2024年1月31日。加权平均差(WMD)和比值比(OR)以及相应的95%置信区间(CI)使用随机效应模型对连续和分类结果进行估计。分别。
    结果:共20个RCTs,包括1528例患者。与钢板固定相比,IMN显著缩短手术时间(WMD=-10.73分钟,95CI:-15.93至-5.52),工会时间(WMD=-1.56周,95CI:-2.82至-0.30),和部分(WMD=-1.71周,95CI:-1.91至-0.43)和完整(WMD=-2.61周,95CI:-3.53至-1.70)负重时间。IMN与伤口感染(OR=0.44,95CI:0.31-0.63)和二次手术(OR=0.72,95CI:0.55-0.95)的风险显着降低相关,但增加了不愈合(OR=1.53,95CI:1.02-2.30)和前膝疼痛(OR=3.94,95CI:1.68-9.28)的风险。骨不连的比率,延迟工会,两组的功能评估评分无显著差异.术后获得出色功能结果或出色和良好功能结果的患者百分比相当。
    结论:IMN和钢板内固定都是治疗胫骨远端骨折的有效方法。IMN似乎是首选,因为它赋予了更多的优势,但是畸形愈合和膝盖疼痛的发生率升高需要注意。固定方式的决定应针对特定的骨折,考虑到这些利弊。
    BACKGROUND: Intramedullary nail (IMN) and plate fixation are the most commonly used surgical modalities for distal tibia fractures. However, the superiority of their efficacy regarding functional outcomes and complications remains controversial. Here, we performed a systematic review and meta-analysis to compare the efficacy of these two modalities.
    METHODS: Randomized controlled trials (RCTs) comparing the efficacy of IMN and plate fixation in distal tibia fractures were searched in PubMed, Web of Science, EMBASE, ClinicalTrials.gov, and Cochrane Library up to January 31, 2024. Weighted mean difference (WMD) and odds ratio (OR) with corresponding 95% confidence interval (CI) were estimated using a random-effect model for continuous and categorical outcomes, respectively.
    RESULTS: A total of 20 RCTs comprising 1528 patients were included. Compared with plate fixation, IMN significantly shortened surgery time (WMD=-10.73 min, 95%CI: -15.93 to -5.52), union time (WMD=-1.56 weeks, 95%CI: -2.82 to -0.30), and partial (WMD=-1.71 weeks, 95%CI: -1.91 to -0.43) and full (WMD=-2.61 weeks, 95%CI: -3.53 to -1.70) weight-bearing time. IMN was associated with markedly reduced risk of wound infection (OR = 0.44, 95%CI: 0.31-0.63) and secondary procedures (OR = 0.72, 95%CI: 0.55-0.95), but increased the risk of malunion (OR = 1.53, 95%CI: 1.02-2.30) and anterior knee pain (OR = 3.94, 95%CI: 1.68-9.28). The rates of nonunion, delayed union, and functional assessment scores did not significantly differ between the two groups. The percentages of patients obtaining an excellent functional outcome or an excellent and good functional outcome post-operation were comparable.
    CONCLUSIONS: Both IMN and plate fixation are effective modalities for the surgical treatment of distal tibia fractures. IMN seems to be preferred since it confers more advantages, but the elevated rates of malunion and knee pain require attention. The decision on fixation modality should be tailored to the specific fracture, considering these pros and cons.
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  • 文章类型: Journal Article
    胆结石发病率的增加可能与以前的胃切除术(PG)有关。然而,胃切除术后内镜逆行胰胆管造影术的成功率明显降低。在这种情况下,腹腔镜经胆囊胆总管探查术(LTCBDE)可能是一种替代方法。在这项研究中,评估了LTCBDE在PG患者中的安全性和可行性。我们回顾性评估了2015年1月至2023年6月期间300例接受LTCBDE治疗的患者。根据PG状态分为2组:PG组和No-PG组。比较2组围手术期资料。PG组手术时间长于No-PG组(184.69±20.28分钟vs152.19±26.37分钟,P<.01)。术中出血量差异无统计学意义(61.19±41.65mLvs50.83±30.47mL,P=.087),术后住院时间(6.36±1.94天vs5.94±1.36天,P=.125),总并发症发生率(18.6%vs14.1%,P=.382),结石清除率(93.2%vs96.3%,P=.303),结石复发率(3.4%vs1.7%,P=.395),和转化率(6.8%对7.0%,P=0.941)两组之间。两组均无死亡病例。胃切除术史可能不会影响LTCBDE的可行性和安全性,因为其围手术期结果与有非胃切除术史的患者相当。
    The increased incidence of gallstones can be linked to previous gastrectomy (PG). However, the success rate of endoscopic retrograde cholangiopan-creatography after gastrectomy has significantly reduced. In such cases, laparoscopic transcystic common bile duct exploration (LTCBDE) may be an alternative. In this study, LTCBDE was evaluated for its safety and feasibility in patients with PG. We retrospectively evaluated 300 patients who underwent LTCBDE between January 2015 and June 2023. The subjects were divided into 2 groups according to their PG status: PG group and No-PG group. The perioperative data from the 2 groups were compared. The operation time in the PG group was longer than that in the No-PG group (184.69 ± 20.28 minutes vs 152.19 ± 26.37 minutes, P < .01). There was no significant difference in intraoperative blood loss (61.19 ± 41.65 mL vs 50.83 ± 30.47 mL, P = .087), postoperative hospital stay (6.36 ± 1.94 days vs 5.94 ± 1.36 days, P = .125), total complication rate (18.6 % vs 14.1 %, P = .382), stone clearance rate (93.2 % vs 96.3 %, P = .303), stone recurrence rate (3.4 % vs 1.7 %, P = .395), and conversion rate (6.8 % vs 7.0 %, P = .941) between the 2 groups. No deaths occurred in either groups. A history of gastrectomy may not affect the feasibility and safety of LTCBDE, because its perioperative results are comparable to those of patients with a history of No-gastrectomy.
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  • 文章类型: Journal Article
    结直肠癌是最常见的消化道肿瘤之一。
    评估腹腔镜结直肠癌手术的可行性和安全性。
    本研究回顾性分析2015-2021年我院收治的48例结直肠癌患者术后早期临床资料,其中21例接受腹腔镜结直肠手术治疗,27人接受了剖腹手术。临床资料差异无统计学意义。如果患者患有结直肠癌(手术前经结肠镜检查和活检病理检查证实),在手术前评估可能的根治性手术,没有肠梗阻,肿瘤侵犯邻近器官(通过直肠指检和术前腹部彩色多普勒超声,CT证实)且无其他腹部手术史。采用临床对照研究的方法,操作时间,术中失血,术后一般情况,手术切除淋巴结(术后病理),手术并发症,胃肠功能恢复,手术前后血糖,体温,白细胞,疼痛视觉模拟量表(VAS)等情况进行对比分析,确定腹腔镜结直肠癌手术的可行性和安全性。
    结直肠癌通过腹腔镜根治术成功切除,没有任何重大问题或手术死亡。年龄,性别,肿瘤位置,舞台,腹腔镜和开腹手术的手术时间没有差异.与剖腹手术相比,术后进食,排便,血糖水平改善。VAS测量后,手术切除的标本长度的变化揭示了开放和腹腔镜手术。总淋巴结计数为10.8±1.6,两种技术之间没有差异。
    腹腔镜结直肠癌根治术是安全可行的。此外,具有微创手术的优点。腹腔镜结直肠癌根治术能符合肿瘤学革命性的原则。
    UNASSIGNED: Colorectal cancer is one of the most common digestive tract tumors.
    UNASSIGNED: To evaluate the feasibility and safety of laparoscopic colorectal cancer surgery.
    UNASSIGNED: This study retrospectively analyzed early postoperative clinical data of 48 patients with colorectal cancer treated in our hospital between 2015 and 2021, of which 21 underwent laparoscopic colorectal surgery, and 27 underwent laparotomy. There was no significant difference in clinical data. Patients were included if they had colorectal cancer (confirmed by colonoscopy and biopsy pathological examination before surgery), were evaluated for possible radical surgery before surgery, and had no intestinal obstruction, tumor invasion of adjacent organs (by digital rectal examination and preoperative abdominal color Doppler ultrasound, CT confirmed) and no other history of abdominal surgery. Using the method of clinical control study, operation time, intraoperative blood loss, postoperative general condition, surgical lymph node removal (postoperative pathology), surgical complications, gastrointestinal function recovery, surgical before and after blood glucose, body temperature, white blood cells, pain visual analog scale (VAS) and other conditions were compared and analyzed to determine feasibility and safety of laparoscopic surgery for colorectal cancer.
    UNASSIGNED: Colorectal cancer was successfully removed by laparoscopic radical resection without any significant problems or surgical fatalities. Age, gender, tumor location, stage, and duration of surgery did not differ between laparoscopic and laparotomy operations. Compared to laparotomy, postoperative eating, bowel movements, and blood sugar levels improved. Variations in the length of surgically removed specimens after VAS measurements revealed open and laparoscopic operations. The overall lymph node count was 10.8 ± 1.6, with no variation between the two techniques.
    UNASSIGNED: Laparoscopic colorectal cancer radical surgery is safe and feasible. Also, it has the advantages of minimally invasive surgery. Laparoscopic colorectal cancer radical surgery can comply with the principles of oncology revolutionary.
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  • 文章类型: Journal Article
    背景:腹股沟疝是机器人或腹腔镜前列腺癌根治术(RP)后常见的并发症之一。RP后腹股沟疝的经腹腹膜前补片成形术(TAPP)由于术后腹膜前腔严重粘连而难以进行。我们在TAPP中引入了一种高腹膜切口方法(HPIA),用于腹股沟疝患者,由于RP后严重粘连而难以进行腹膜解剖。我们评估了TAPP与HPIA对机器人辅助RP(RARP)术后腹股沟疝患者的安全性和有效性。
    方法:通过回顾性分析评估患者特征和手术结果。
    结果:从2014年1月至2017年12月,连续21例患者在RARP术后接受TAPP治疗腹股沟疝。根据Nyhus分类,24个病变为3b型,3个为3a型。对8例患者的10例疝气病变进行了环形切口TAPP,对13例患者的17例病变使用了HPIA的TAPP。HPIA单侧疝的平均手术时间(137.8±20.7分钟)明显短于圆形切口TAPP的(182.2±42.0分钟)(p=.038)。所有患者的HPIA都完成了,5例患者将圆形切口TAPP转换为腹膜内嵌网(IPOM)腹膜内嵌网(55.6%,p=.008),由于粘连致密,解剖困难。随访48个月后,两组均未出现复发。
    结论:对于RARP术后腹股沟疝患者,TAPP联合HPIA是可行的,是一种安全可靠的选择。
    BACKGROUND: Inguinal hernia develops as one of the common complications after robotic or laparoscopic radical prostatectomy (RP). Transabdominal preperitoneal patch plasty (TAPP) for an inguinal hernia after RP is difficult to perform due to postoperative severe adhesions in the preperitoneal cavity. We have introduced a high peritoneal incision approach (HPIA) in TAPP for inguinal hernia patients in whom peritoneal dissection is difficult due to severe adhesions after RP. We evaluate the safety and efficacy of TAPP with a HPIA for patients with an inguinal hernia after robot-assisted RP (RARP).
    METHODS: Patients characteristics and surgical outcome were evaluated by a retrospective analysis.
    RESULTS: From January 2014 to December 2017, 21 consecutive patients underwent TAPP for an inguinal hernia after RARP. Twenty-four lesions were the type 3b and three were type 3a according to the Nyhus classification. A circular incision TAPP was performed for 10 hernia lesions in eight patients and TAPP with HPIA was utilized for 17 lesions in 13 patients. The mean operation time for the unilateral hernia in the HPIA (137.8 ± 20.7 min) was significantly shorter than that (182.2 ± 42.0 min) in the circular incision TAPP (p = .038). The HPIA was complete in all patients, while the circular incision TAPP was converted to intraperitoneal onlay mesh (IPOM)intraperitoneal onlay mesh in five patients (55.6%, p = .008) due to dense adhesions with difficult dissection. No recurrent was observed after follow-up period of 48 months in both groups.
    CONCLUSIONS: The TAPP with HPIA is feasible and a safe and reliable treatment of choice in patients with an inguinal hernia after RARP.
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  • 文章类型: Journal Article
    背景:肺切除术后常见术后并发症的危险因素之间的关系,如空气泄漏,肺不张,和心律不齐,和患者特征,包括营养状况或围手术期因素,还没有被充分阐明。
    方法:回顾性分析接受肺切除术治疗的99例非小细胞肺癌患者术后常见并发症的危险因素。
    结果:在多变量分析中,男性(P=0.01),年龄≥65岁(P<0.01),慢性阻塞性肺疾病(COPD)的共存(P<0.01),上叶(P<0.01),手术时间≥155min(P<0.01),淋巴浸润(P=0.01)是术后并发症的重要因素。男性(P<0.01),年龄≥65岁(P=0.02),体重指数(BMI)<21.68(P<0.01),COPD共存(P=0.02),手术时间≥155min(P=0.01)是术后严重并发症的重要因素。男性(P=0.01),BMI<21.68(P<0.01),胸腔镜手术(P<0.01),手术时间≥155min(P<0.01)是术后漏气的危险因素。COPD共存(P=0.01)和哮喘共存(P<0.01)是术后肺不张的危险因素。预后营养指数(PNI)<45.52(P<0.01),肺叶切除术或扩大切除术多于肺叶切除术(P=0.01),手术时间≥155min(P<0.01)是术后心律失常的危险因素。
    结论:低BMI,胸腔镜手术,手术时间较长是术后漏气的重要危险因素。COPD共存和哮喘共存是术后肺不张的重要危险因素。PNI,手术时间,和手术方式是术后心律失常的危险因素。有这些因素的患者应监测术后并发症。
    背景:金泽医科大学机构审查委员会批准了这项回顾性研究的方案(批准号:I392),并获得所有患者的书面知情同意书.
    BACKGROUND: The relationship between risk factors of common postoperative complications after pulmonary resection, such as air leakage, atelectasis, and arrhythmia, and patient characteristics, including nutritional status or perioperative factors, has not been sufficiently elucidated.
    METHODS: One thousand one hundred thirty-nine non-small cell lung cancer patients who underwent pulmonary resection were retrospectively analyzed for risk factors of common postoperative complications.
    RESULTS: In a multivariate analysis, male sex (P = 0.01), age ≥ 65 years (P < 0.01), coexistence of chronic obstructive pulmonary disease (COPD) (P < 0.01), upper lobe (P < 0.01), surgery time ≥ 155 min (P < 0.01), and presence of lymphatic invasion (P = 0.01) were significant factors for postoperative complication. Male sex (P < 0.01), age ≥ 65 years (P = 0.02), body mass index (BMI) < 21.68 (P < 0.01), coexistence of COPD (P = 0.02), and surgery time ≥ 155 min (P = 0.01) were significant factors for severe postoperative complication. Male sex (P = 0.01), BMI < 21.68 (P < 0.01), thoracoscopic surgery (P < 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative air leakage. Coexistence of COPD (P = 0.01) and coexistence of asthma (P < 0.01) were significant risk factors for postoperative atelectasis. Prognostic nutrition index (PNI) < 45.52 (P < 0.01), lobectomy or extended resection more than lobectomy (P = 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative arrhythmia.
    CONCLUSIONS: Low BMI, thoracoscopic surgery, and longer surgery time were significant risk factors for postoperative air leakage. Coexistence of COPD and coexistence of asthma were significant risk factors for postoperative atelectasis. PNI, surgery time, and surgical procedure were revealed as risk factors of postoperative arrhythmia. Patients with these factors should be monitored for postoperative complication.
    BACKGROUND: The Institutional Review Board of Kanazawa Medical University approved the protocol of this retrospective study (approval number: I392), and written informed consent was obtained from all patients.
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  • 文章类型: Journal Article
    背景:比较腹腔镜胰十二指肠切除术(LPD)与开腹胰十二指肠切除术(OPD)治疗壶腹癌(AC)的研究有限。这项研究旨在比较AC的LPD和OPD的短期和长期结果。
    方法:本研究纳入了2008年4月至2023年3月在大崎市立医院接受胰十二指肠切除术(PD)治疗的AC患者。
    结果:55例患者接受了LPD(n=26)或OPD(n=29)。两组人口统计学差异无统计学意义。LPD组的手术时间明显更长(268vs.225分钟),减少失血(125vs.450mL),术后住院时间较短(18vs.23天)比OPD组。发病率没有显着差异。LPD组比OPD组收集的淋巴结少(9.5vs.16.0),但在淋巴结转移或病理分期上无明显差异。总生存期(OS)或无复发生存期(RFS)无显著差异。LPD组和OPD组的3年和5年OS率分别为63.0%和54%,64.8%,和61.2%,分别。3年和5年RFS率分别为57.4%和57.4%,58.1%,和54.4%,分别。
    结论:LPD治疗AC的短期和长期结果与OPD相当。LPD可以被认为是AC的标准治疗,因为其失血更少并且住院时间更短。
    BACKGROUND: Studies comparing laparoscopic pancreaticoduodenectomy (LPD) with open pancreaticoduodenectomy (OPD) for ampullary carcinoma (AC) are limited. This study aimed to compare short- and long-term outcomes between LPD and OPD for AC.
    METHODS: This study included patients with AC who underwent pancreaticoduodenectomy (PD) with curative intention at Ogaki Municipal Hospital from April 2008 to March 2023.
    RESULTS: Fifty-five patients underwent LPD (n = 26) or OPD (n = 29). There were no significant differences in the demographics between the two groups. The LPD group had a significantly longer operative time (268 vs. 225 min), less blood loss (125 vs. 450 mL), and shorter postoperative hospital stay (18 vs. 23 days) than the OPD group. There was no significant difference in the morbidity ratio. Fewer lymph nodes were harvested in the LPD group than OPD group (9.5 vs. 16.0), but there were no significant differences in lymph node metastasis or pathological stages. There were no significant differences in overall survival (OS) or recurrence-free survival (RFS). The 3- and 5-year OS rates in the LPD group and the OPD group were 63.0% and 54%, 64.8%, and 61.2%, respectively. The 3- and 5-year RFS rates were 57.4% and 57.4%, 58.1%, and 54.4%, respectively.
    CONCLUSIONS: LPD for AC had short- and long-term outcomes comparable with those of OPD. LPD could be considered the standard treatments for AC because of less blood loss and a shorter hospital stay.
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  • 文章类型: Journal Article
    背景:达芬奇手术系统(X和Xi)是由IntuitiveInc.销售的第四代系统。X系统比Xi系统便宜。这项研究比较了使用X和Xi系统进行子宫切除术的患者的手术结果。
    方法:在一项单中心研究中,回顾性分析了在2019年4月至2023年3月期间由四名外科医生接受机器人辅助全子宫切除术的172名患者的数据。根据所使用的手术系统将患者分为两组。鸟取大学医院机构审查委员会(22A134)批准。所有患者都按照机构指南提供了选择退出同意书。
    结果:手术时间(X为126.6±29.5,Xi为138.2±38.5,p=.227)和控制台时间(X为92.9±27.0,Xi为105.5±34.7,p=.089)在年龄倾向评分匹配后,X组比Xi组短,身体质量指数,无效,既往腹部或骨盆手术史,术前诊断,和手术方法。在接受机器人辅助无淋巴结清扫的全腹腔镜子宫切除术的患者的亚组分析中,X和Xi之间没有显着差异(手术时间:X为199.0±26.5,Xi为221.5±45.1,p=.227;控制台时间:X为162.1±25.0,Xi为178.3±0.314,p=.314)。
    结论:X和XidaVinci手术系统的围手术期结果相当。具有成本效益的X系统可以允许广泛使用机器人手术。
    BACKGROUND: The da Vinci surgical systems (X and Xi) are fourth-generation systems marketed by Intuitive Inc. The X system is less expensive than the Xi system. This study compared the surgical outcomes of patients who underwent hysterectomy using the X and Xi systems.
    METHODS: Data from 172 patients who underwent robot-assisted total hysterectomies by four surgeons between April 2019 and March 2023 were retrospectively analyzed in a single-center study. The patients were divided into two groups based on the surgical system used. Approval was granted by the Institutional Review Board of the Tottori University Hospital (22A134). All patients provided opt-out consent in accordance with the institutional guidelines.
    RESULTS: Operative time (126.6 ± 29.5 for X, 138.2 ± 38.5 for Xi, p = .227) and console time (92.9 ± 27.0 for X, 105.5 ± 34.7 for Xi, p = .089) were insignificantly shorter in group X than in group Xi after propensity score matching for age, body mass index, nulliparity, previous history of abdominal or pelvic surgery, preoperative diagnosis, and surgical approach. No significant differences between X and Xi were observed in a subgroup analysis of patients who underwent robot-assisted total laparoscopic hysterectomy without lymphadenectomy (operative time: 199.0 ± 26.5 for X, 221.5 ± 45.1 for Xi, p = .227; console time: 162.1 ± 25.0 for X, 178.3 ± 0.314 for Xi, p = .314).
    CONCLUSIONS: Perioperative outcomes for the X and Xi da Vinci surgical systems were equivalent. The cost-effective X system may allow the widespread use of robotic surgeries.
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  • 文章类型: Comparative Study
    背景:评估腹腔镜结直肠切除术中低腹内压和高腹内压的结果。
    方法:对多个电子数据源进行了系统搜索,纳入了所有比较低和高(标准)腹内压的研究.我们的主要结果是术后肠梗阻的发生和肠蠕动/排气的恢复。评估的次要结果包括:总手术时间,术后出血,吻合口漏,肺炎,手术部位感染,术后总体并发症(按Clavien-Dindo分级分类),和住院时间。使用Revman5.4进行数据分析。
    结果:共纳入6项随机对照试验(RCT)和1项观察性研究,共771例患者(370例低腹压手术,401例高腹压手术)。所有测量结果无统计学差异;术后肠梗阻[OR0.80;CI(0.42,1.52),P=0.50],排气时间[OR-4.31;CI(-12.12,3.50),P=0.28],总手术时间[OR0.40;CI(-10.19,11.00),P=0.94],术后出血[OR1.51;CI(0.41,5.58,P=0.53],吻合口漏[OR1.14;CI(0.26,4.91),P=0.86],肺炎[OR1.15;CI(0.22,6.09),P=0.87],SSI[OR0.69;CI(0.19,2.47),P=0.57],术后总并发症[OR0.82;CI(0.52,1.30),P=0.40],Clavien-Dindo等级≥3[OR1.27;CI(0.59,2.77),P=0.54],和住院时间[OR-0.68;CI(-1.61,0.24),P=0.15]。
    结论:低腹内压是腹腔镜结直肠切除术安全可行的方法,其结局不低于标准或高压。需要更强大且功能良好的RCT来巩固低压高于高压的腹腔内手术的潜在益处。
    BACKGROUND: To evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.
    METHODS: A systematic search of multiple electronic data sources was conducted, and all studies comparing low with high (standard) intraabdominal pressures were included. Our primary outcomes were post-operative ileus occurrence and return of bowel movement/flatus. The evaluated secondary outcomes included: total operative time, post-operative haemorrhage, anastomotic leak, pneumonia, surgical site infection, overall post-operative complications (categorised by Clavien-Dindo grading), and length of hospital stay. Revman 5.4 was used for data analysis.
    RESULTS: Six randomised controlled trials (RCTs) and one observational study with a total of 771 patients (370 surgery at low intraabdominal pressure and 401 at high pressures) were included. There was no statistically significant difference in all the measured outcomes; post-operative ileus [OR 0.80; CI (0.42, 1.52), P = 0.50], time-to-pass flatus [OR -4.31; CI (-12.12, 3.50), P = 0.28], total operative time [OR 0.40; CI (-10.19, 11.00), P = 0.94], post-operative haemorrhage [OR 1.51; CI (0.41, 5.58, P = 0.53], anastomotic leak [OR 1.14; CI (0.26, 4.91), P = 0.86], pneumonia [OR 1.15; CI (0.22, 6.09), P = 0.87], SSI [OR 0.69; CI (0.19, 2.47), P = 0.57], overall post-operative complications [OR 0.82; CI (0.52, 1.30), P = 0.40], Clavien-Dindo grade ≥ 3 [OR 1.27; CI (0.59, 2.77), P = 0.54], and length of hospital stay [OR -0.68; CI (-1.61, 0.24), P = 0.15].
    CONCLUSIONS: Low intraabdominal pressure is safe and feasible approach to laparoscopic colorectal resection surgery with non-inferior outcomes to standard or high pressures. More robust and well-powered RCTs are needed to consolidate the potential benefits of low over high pressure intra-abdominal surgery.
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  • 文章类型: Journal Article
    目的:先前的研究表明,与开放修补术(OR)相比,胸腔镜(TR)先天性膈疝(CDH)的复发率更高,手术时间更长。进行了更新的荟萃分析以重新评估TR的手术结果。
    方法:根据PRISMA声明(PROSPERO:CRD42020166588),对新生儿的TR和OR进行了全面的文献检索。
    结果:选择了14项研究进行定量分析,包括总共709例患者(TR:308例,或:401例)。复发率较高[赔率:4.03,95%CI(2.21,7.36),p<0.001]和手术时间(分钟)更长[平均差(MD):43.96,95%CI(24.70,63.22),与OR相比,TR的p<0.001。与OR(14.8%)相比,TR(5.0%)观察到术后肠梗阻的发生率显着降低[赔率:0.42,95%CI(0.20,0.89),p=0.02]。
    结论:TR仍然与较高的复发率和较长的手术时间相关。然而,术后肠梗阻风险降低提示潜在的长期益处.这项研究强调了精心选择TR患者以减轻对严重疾病患者的不利影响的重要性。
    OBJECTIVE: Previous studies have shown a higher recurrence rate and longer operative times for thoracoscopic repair (TR) of congenital diaphragmatic hernia (CDH) compared to open repair (OR). An updated meta-analysis was conducted to re-evaluate the surgical outcomes of TR.
    METHODS: A comprehensive literature search comparing TR and OR in neonates was performed in accordance with the PRISMA statement (PROSPERO: CRD42020166588).
    RESULTS: Fourteen studies were selected for quantitative analysis, including a total of 709 patients (TR: 308 cases, OR: 401 cases). The recurrence rate was higher [Odds ratio: 4.03, 95% CI (2.21, 7.36), p < 0.001] and operative times (minutes) were longer [Mean Difference (MD): 43.96, 95% CI (24.70, 63.22), p < 0.001] for TR compared to OR. A significant reduction in the occurrence of postoperative bowel obstruction was observed in TR (5.0%) compared to OR (14.8%) [Odds ratio: 0.42, 95% CI (0.20, 0.89), p = 0.02].
    CONCLUSIONS: TR remains associated with higher recurrence rates and longer operative times. However, the reduced risk of postoperative bowel obstruction suggests potential long-term benefits. This study emphasizes the importance of meticulous patient selection for TR to mitigate detrimental effects on patients with severe disease.
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