Operative time

手术时间
  • 文章类型: Journal Article
    背景:卡氏胸(PC)主要存在于青少年早期或青春期的生长高峰时期。外貌不佳是寻求外科医生帮助以增强自信心和自尊的主要原因。目前,微创修复是矫正胸壁畸形的有效方法之一。因此,开展青少年PC的MIR临床研究具有重要的现实意义。
    方法:我们在PC组中应用了Abramson程序,或者在PC/PE组中应用了Abramson程序和Nuss程序。我们回顾性回顾了2020年1月至2023年4月在我科接受手术矫正的41例患者的结果。
    结果:所有手术均成功完成,无严重并发症。PC组中位手术时间为80min,PC/PE组为130min。PC组LOS中位数为4天,PC/PE组为5天。PC组压缩深度中位数为32mm,PC/PE组为12mm。术后,有一些并发症。两组9例气胸患者均接受保守治疗。一名患者术后过度矫正。两组均有3例钢丝断裂。一名患者术后再次手术,导致钢丝断裂导致棒材脱位。
    结论:Abramson程序或Abramson程序和Nuss程序在修复PC和PC/PE方面具有良好的短期效果。根据Abramson程序后下平面是否过度压下,应分别选择一个或两个程序。
    BACKGROUND: Pectus carinatum (PC) mainly present at the growth spurt time of the early teenage years or the puberty. Poor outer appearance is a major reason for seeking help for surgeons to increase self-confidence and self-esteem. At present, minimally invasive repair (MIR) is one of effective ways to correct the chest wall deformity. Therefore, there is great practical significance to conduct clinical research on MIR about the adolescent PC.
    METHODS: We applied Abramson procedure in PC group or we applied Abramson procedure and Nuss procedure in PC/PE group. We retrospectively reviewed the results of 41 cases who underwent the surgical correction at our department from January 2020 to April 2023.
    RESULTS: All the procedures were successfully done without severe complications. The median operation Time was 80 min in PC group while was 130 min in PC/PE group. The median LOS were 4 days in PC group while 5 days in PC/PE group. The median compression depth was 32 mm in PC group while 12 mm in PC/PE group. Postoperatively, there are some complications. All Pneumothorax patients being treated conservatively were found in 9 patients in two groups. One patient suffered overcorrection after operation. There were 3 patients suffered steel wires breakage in two groups. One patient reoperation postoperatively for the dislocation of the bar secondary to steel wires breakage.
    CONCLUSIONS: The Abramson procedure or Abramson procedure and Nuss procedure have good short-term results in repair PC and PC/PE. Select one or two procedures should be done individually based on whether the lower plane over depressed after Abramson procedure.
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  • 文章类型: Journal Article
    胃肠道间质瘤(GIST),胃肠道中最常见的间充质肿瘤,越来越多地接受微创手术治疗。开发的技术包括腹腔镜,内窥镜,和胃GIST切除术的混合方法。我们的研究,以单切口腹腔镜胃内切除术为重点,旨在评估其安全性,功效,和长期结果。在一项涉及14例接受单切口腹腔镜胃内切除术的GIST手术的回顾性研究中,我们分析并比较了他们的术前人口统计学,美国麻醉医师协会(ASA)评分,肿瘤大小,新辅助治疗,操作持续时间,住院,有丝分裂和Ki-67指数,以及接受开放和腹腔镜楔形切除术的患者的组织学特征,评估对生存率和无病生存率的影响。平均手术时间为93.07分钟(范围81-120分钟)。平均失血量:67±20mL(范围40-110mL)。术后住院时间平均为6.79天(4-16天)。术前肿瘤大小和病理大小之间观察到强烈的相关性(P=.001,P<.001)。生存分析表明与ASA评分显著相关(P=.031),但没有有丝分裂指数,Ki-67或肿瘤大小。平均生存期为80.57个月,随访期间无复发或转移。根据我们的经验,单切口腹腔镜胃内切除术方法是一种高效的,节省时间,温和的肿瘤学程序,提供安全和微创的替代方案,从而缩短住院时间和出色的长期结局,同时复发率最低。对于更明确的结论,较大,多中心,并建议进行前瞻性研究。
    Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors in the gastrointestinal tract, are increasingly treated with minimally invasive surgeries. Developed techniques include laparoscopic, endoscopic, and hybrid methods for gastric GIST resection. Our study, focusing on single-incision laparoscopic intragastric resection for gastric GISTs, aims to evaluate its safety, efficacy, and long-term outcomes. In a retrospective study of GIST surgery involving 14 patients who underwent single-incision laparoscopic intragastric resections, we analyzed and compared their preoperative demographics, American Society of Anesthesiologists (ASA) scores, tumor size, neoadjuvant treatment, operation duration, hospital stay, mitotic and Ki-67 indexes, and histological features with those of patients who underwent open and laparoscopic wedge resections, to assess the impact on both survival and disease-free survival. Average operation time was 93.07 minutes (range 81-120 minutes). Average blood loss: 67 ± 20 mL (range 40-110 mL). Postoperative hospital stay averaged 6.79 days (range 4-16 days). Strong correlations were observed between preoperative and pathological tumor sizes (P = .001, P < .001). Survival analysis indicated a significant association with ASA scores (P = .031), but not with mitotic index, Ki-67, or tumor size. Average survival was 80.57 months, with no recurrence or metastasis during follow-up. Based on our experience, the single-incision laparoscopic intragastric resection method emerges as a highly efficient, timesaving, and gentle oncological procedure, providing a safe and minimally invasive alternative resulting in shorter hospital stays and excellent long-term outcomes with minimal recurrence. For more definitive conclusions, larger, multicenter, and prospective studies are recommended.
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  • 文章类型: Journal Article
    视网膜前膜(ERM)在玻璃体视网膜病理学中提出了共同的挑战,经常导致老年人视力障碍。预眼手术系统(PSS)支持通过机器人辅助膜剥离(RA-MP)手术去除ERM。这项研究比较了使用PSS进行手动膜剥离(MMP)和RA-MP之间的手术时间和医源性出血。
    9例患者接受RA-MP和PSS,而16例患者(18只眼)接受了MMP进行比较分析。手术持续时间分为RA-MP,手动钳在PSS手术中的使用(mRA-MP),传统的MMP。累积手动操作持续时间(cMMP),仪表夹具,术中出血采用Mann-WhitneyU检验进行统计学分析。
    与MMP相比,RA-MP显示出明显更长的剥离时间(P<0.001)。方法之间的皮瓣起始抓握相似(P=0.86),RA-MP显示出剥离抓取(P=0.01)和平均每分钟抓取(P<0.001)的显著减少。虽然RA-MP导致较少的出血,与MMP相比,差异无统计学意义(P=0.08).
    尽管RA-MP倾向于延长手术时间,它在减少组织创伤和术中出血方面具有优势。需要进一步的研究来探索新手外科医生的学习曲线并评估RA-MP的安全性。
    RA-MP可能比手动手术具有潜在的优势,特别是在减少组织创伤和术中出血方面。尽管与手动技术相比,其持续时间更长,RA-MP可能导致更少的抓握动作和更低的出血率,从而提高玻璃体视网膜手术的安全性和精确性。
    UNASSIGNED: Epiretinal membranes (ERM) pose a common challenge in vitreoretinal pathology, often causing vision impairment in older adults. The Preceyes Surgical System (PSS) supports the surgical removal of ERM through robot-assisted membrane peeling (RA-MP). This study compares surgical times and iatrogenic hemorrhages between manual membrane peeling (MMP) and RA-MP using PSS.
    UNASSIGNED: Nine patients underwent RA-MP with PSS, whereas 16 patients (18 eyes) underwent MMP for comparative analysis. Surgical durations were categorized into RA-MP, manual forceps utilization in PSS surgeries (mRA-MP), and traditional MMP. Cumulative manual manipulation duration (cMMP), instrument grasps, and intraoperative hemorrhages were statistically analyzed using the Mann-Whitney U test.
    UNASSIGNED: RA-MP showed significantly longer peeling times compared to MMP (P < 0.001). Flap initiation grasps were similar between methods (P = 0.86), RA-MP demonstrated a significant reduction in peeling grasps (P = 0.01) and mean grasps per minute (P < 0.001). Although RA-MP resulted in fewer hemorrhages, the difference did not reach statistical significance relative to MMP (P = 0.08).
    UNASSIGNED: Although RA-MP tended to extend surgical time, it offered advantages in reducing tissue trauma and intraoperative hemorrhages. Further research is needed to explore the learning curve for novice surgeons and evaluate the safety profile of RA-MP.
    UNASSIGNED: RA-MP may offer potential advantages over manual surgery, particularly in terms of reduced tissue trauma and intraoperative hemorrhages. Despite its longer duration compared with manual techniques, RA-MP may lead to fewer grasping maneuvers and lower rates of hemorrhages, thereby enhancing the safety and precision of vitreoretinal surgeries.
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  • 文章类型: Meta-Analysis
    背景:阑尾炎是全球最常见的急性外科疾病之一。然而,夜间阑尾切除术与患者发病率和死亡率之间的关系尚不清楚.这项研究旨在比较夜间和白天阑尾切除术后的结果。
    方法:PubMed,Embase,科克伦图书馆,和截至2024年3月26日的WebofScience数据库(更新于2024年7月1日)进行了搜索。主要结果是术后并发症和死亡率。次要结果包括术中并发症,再操作,重新接纳,转换为剖腹手术,住院时间和手术时间。计算平均差(MD)或比值比(OR)和95%置信区间。
    结果:共纳入15项研究,共33,596名患者。夜间和日间阑尾切除术的总体术后并发症发生率没有差异(OR0.93,95%CI0.87,1.00,14项研究),死亡率(OR1.70,95%CI0.37,7.88,7项研究),术中并发症(OR0.88,95%CI0.08,9.86;2项研究),再手术(OR0.39,95%CI0.06,2.55;3项研究)和再入院(OR0.86,95%CI0.65,1.13;I2=0%,5项研究)。然而,与日间相比,夜间行阑尾切除术的患者转换为剖腹手术的风险(OR1.92,95%CI1.12,3.29;6项研究)显著升高.
    结论:与日间阑尾切除术相比,夜间手术的术后死亡率和并发症发生率没有增加或差异。然而,未来的研究应评估夜间转化率较高的原因.
    BACKGROUND: Appendicitis is one of the most common acute surgical conditions globally. However, the association between nighttime appendectomy and patients\' morbidity and mortality is unclear. This study aims to compare outcomes following nighttime versus daytime appendectomy.
    METHODS: The PubMed, Embase, Cochrane Library, and Web of Science databases up to March 26, 2024 (updated on July 1, 2024) were searched. The primary outcomes were postoperative complications and mortality. Secondary outcomes included intraoperative complications, reoperation, readmission, conversion to laparotomy, hospital stay and operation time. Mean difference (MD) or odds ratios (OR) and 95% confidence intervals were calculated.
    RESULTS: Fifteen studies totaling 33,596 patients were included. There were no differences between nighttime and daytime appendectomy for rates of overall postoperative complications (OR 0.93, 95% CI 0.87, 1.00, 14 studies), mortality (OR 1.70, 95% CI 0.37, 7.88, 7 studies), intraoperative complications (OR 0.88, 95% CI 0.08, 9.86; 2 studies), reoperation (OR 0.39, 95% CI 0.06, 2.55; 3 studies) and readmission (OR 0.86, 95% CI 0.65, 1.13; I2 = 0%, 5 studies). However, the conversion to laparotomy risks (OR 1.92, 95% CI 1.12, 3.29; 6 studies) among patients who underwent appendectomy during nighttime was significantly elevated compared to daytime.
    CONCLUSIONS: There was no increased risk or difference in postoperative mortality and complication rates associated with nighttime compared with daytime appendectomy. However, future studies should assess the reasons for higher conversion rates during the night.
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  • 文章类型: Journal Article
    背景:人皮病(PD)是一种获得性疾病,与头发引起的对臀裂皮肤表面的机械力有关,随后形成脓肿,伴有或不伴有引流窦(坑)。虽然目前手术管理是治疗的主要手段,最近,成毛疾病激光治疗(PiLaT)被认为是非炎性疾病的有希望的治疗选择。尽管如此,关于青少年毛发沉积病激光治疗(a-PiLaT)的现有数据很少.
    方法:我们描述了我们从2019年到2023年在三级儿科外科医院对10-17岁青少年进行PiLaT的初步经验。回顾性分析围手术期特征和随访时的临床结果。
    结果:共有17名连续患者(n=12名女性,71%)接受了a-PiLaT。在治疗的时候,患者的平均年龄和体重指数分别为13.6±1.6岁和25.3±5.6kgm-2。平均手术时间为21.5±10.4分钟,而平均随访期为24.5±16.8个月,并发症发生率为24%(n=4),复发率为18%(n=3)。关于术后瘢痕评估,患者和观察者疤痕评估量表的平均评分(评分范围为6~60分,评分越高表示预后越差)分别为14.2±6.5(患者评估)和11.4±4.7(观察者评估).
    结论:a-PiLaT代表了一种管理青少年PD的新方法。我们关于a-PiLaT后一小部分毛囊窦患者结局的初步数据表明,并发症和复发率与文献中报道的成人相当。这种新的微创技术具有巨大的潜力,因此值得在更大的人群中进一步研究。
    BACKGROUND: Pilonidal disease (PD) is an acquired condition related to hair-induced mechanical forces on the skin surface of the intergluteal cleft, with subsequent abscess formation with or without a concomitant draining sinus (pit). While surgical management currently is the mainstay of treatment, pilonidal disease laser treatment (PiLaT) has recently been recognized as a promising treatment option for non-inflammatory diseases. Nonetheless, there is a paucity of available data on adolescent pilonidal disease laser treatment (a-PiLaT).
    METHODS: We describe our preliminary experience with PiLaT performed in adolescents aged 10-17 years at our tertiary paediatric surgical hospital from 2019 to 2023. Data on perioperative characteristics and clinical outcomes at follow-up were retrospectively analysed.
    RESULTS: A total of 17 consecutive patients (n = 12 female, 71%) underwent a-PiLaT. At the time of treatment, the patients\' mean age and body mass index were 13.6 ± 1.6 years and 25.3 ± 5.6 kg m-2, respectively. The mean operative time was 21.5 ± 10.4 min, whereas the mean follow-up period was 24.5 ± 16.8 months, with a complication rate of 24% (n = 4) and recurrence rate of 18% (n = 3). With respect to postsurgical scar assessment, the mean Patient and Observer Scar Assessment Scale scores (score range 6-60, with higher scores indicating worse outcome) were 14.2 ± 6.5 (patients\' evaluation) and 11.4 ± 4.7 (observers\' evaluation).
    CONCLUSIONS: The a-PiLaT represents a novel approach for managing PD in adolescents. Our preliminary data on the outcomes of a small series of patients with pilonidal sinuses after a-PiLaT indicated complication and recurrence rates comparable to those reported in the literature for adults. This new minimally invasive technique has great potential and is therefore worthy of further research on a larger population.
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  • 文章类型: Journal Article
    根治性膀胱切除术是一项与术后发病率相关的复杂冗长的手术。我们旨在评估根治性膀胱切除术患者的手术时间(OT)及其对术后90天并发症和再入院率的影响。
    回顾性队列研究包括2010年5月至2018年12月在我们机构接受根治性膀胱切除术和尿流改道的296例患者。将369分钟的OT设置为短OT和长OT组之间的截止值。主要结果是术后90天并发症发生率。次要结果是胃肠道恢复时间,住院时间,和90天的再入院率。
    术后90天并发症的总发生率为79.7%,其中43.2%表示根据Clavien-Dindo分类(1级和2级)的低度并发症,和36.5%代表高级别并发症(≥3级)。胃肠道和感染性并发症是我们数据集中最常见的并发症(45.9%和45.6%,分别)。在多变量分析中,延长OT与高级别并发症的几率显著相关(比值比2.340,95%置信区间1.288-4.250,p=0.005).经过倾向得分匹配分析,与短OT组的35例(32.7%)相比,长OT组55例(51.4%)的主要并发症发生率更高(p=0.006).短OT组的胃肠道恢复时间较短(p=0.009)。在单变量和多变量分析中,延长的OT与更高的90天再入院率相关(分别为p<0.001,p=0.001)。
    延长OT(>369分钟)与术后并发症和再入院率的风险增加相关。潜在的术后并发症的感知需要仔细监测这些患者,这可以转化为更好的手术结果。
    UNASSIGNED: Radical cystectomy is a complex lengthy procedure associated with postoperative morbidity. We aimed to assess the operative time (OT) in patients undergoing radical cystectomy and its impact on 90-day postoperative complications and readmission rates.
    UNASSIGNED: The retrospective cohort study included 296 patients undergoing radical cystectomy and urinary diversion from May 2010 to December 2018 in our institution. The OT of 369 min was set as a cutoff value between short and long OT groups. The primary outcome was 90-day postoperative complication rates. Secondary outcomes were gastrointestinal recovery time, length of hospital stay, and 90-day readmission rates.
    UNASSIGNED: The overall incidence of 90-day postoperative complications was 79.7% where 43.2% representing low-grade complications according to the Clavien-Dindo classification (Grade 1 and Grade 2), and 36.5% representing high-grade complications (Grade≥3). Gastrointestinal tract and infectious complications are the most common complications in our data set (45.9% and 45.6%, respectively). On multivariable analysis, prolonged OT was significantly associated with odds of high-grade complications (odds ratio 2.340, 95% confidence interval 1.288-4.250, p=0.005). After propensity score-matched analysis, a higher incidence of major complications was identified in the long OT group 55 (51.4%) compared to 35 (32.7%) in the short OT group (p=0.006). A shorter gastrointestinal tract recovery time was noticed in the short OT group (p=0.009). Prolonged OT was associated with a higher 90-day readmission rate on univariate and multivariate analyses (p<0.001, p=0.001, respectively).
    UNASSIGNED: Prolonged OT (>369 min) is associated with an increased risk of postoperative complications and readmission rates. The perception of potential postoperative complications requires careful monitoring of these patients which could translate into better operative outcomes.
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  • 文章类型: Journal Article
    背景:转移结肠造口术后新辅助治疗是梗阻性直肠癌的首选治疗方法。可以通过机器人方法治疗这样的患者,其具有优于常规腹腔镜手术的几个优点。相反,现有的造口可能会干扰套管针的最佳位置,从而影响机器人手术的质量。此外,控制台外科医生不面对病人,这可能会危及造口。
    方法:在我院接受新辅助治疗后,使用机器人平台对接受保括约肌手术的直肠癌患者进行回顾性调查。基于预处理造口的创建,患者分为NS组(无造口组)和S组(有造口组).基线特征,新辅助治疗的类型,短期手术结果,术后肛门直肠测压数据,比较各组之间的生存率。
    结果:NS组和S组包括65和9名患者,分别。NS组的三名患者需要转换为剖腹手术。S组比NS组需要更长的控制台时间(中位数:367vs.253分钟,分别,p=0.038);然而,总手术时间(p=0.15)和失血量(p=0.70)无差异.术后并发症发生率,肛门直肠功能,两组之间的肿瘤结局相似.
    结论:尽管造口患者的控制台时间较长,机器人手术可以像新辅助治疗后没有造口的人一样安全地进行.
    BACKGROUND: Diverting colostomy followed by neoadjuvant treatment is a treatment of choice for obstructive rectal cancer. Such patients may be treated via a robotic approach with several advantages over conventional laparoscopic surgery. Conversely, the existing stoma may interfere with the optimal trocar position and thus affect the quality of robotic surgery. Moreover, the console surgeon does not face the patient, which may endanger the stoma.
    METHODS: Patients with rectal cancer who underwent sphincter-preserving surgery were retrospectively investigated using a robotic platform after neoadjuvant treatment at our hospital. Based on pretreatment stoma creation, patients were divided into the NS (those without a stoma) and S groups (patients with a stoma). Baseline characteristics, types of neoadjuvant treatment, short-term surgical outcomes, postoperative anorectal manometric data, and survival were compared between the groups.
    RESULTS: The NS and S groups comprised 65 and 9 patients, respectively. Conversion to laparotomy was required in three patients in the NS group. The S group required a longer console time than the NS group (median: 367 vs. 253 min, respectively, p = 0.038); however, no difference was observed in the total operative time (p = 0.15) and blood loss (p = 0.70). Postoperative complication rates, anorectal function, and oncological outcomes were similar between the groups.
    CONCLUSIONS: Although console time was longer in patients with a stoma, robotic surgery could be performed safely like in those without a stoma after neoadjuvant treatment.
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  • 文章类型: Journal Article
    内镜黏膜下剥离术(ESD)治疗结直肠纤维化病变难度大,并发症发生率高。关于正畸橡皮筋(ORB)牵引在降低此过程难度方面的实用性,只有很少的报道。本研究旨在探讨在纤维化结直肠病变ESD中应用ORB牵引时发生穿孔的危险因素。我们连续收集了119例纤维化结直肠病变患者的临床资料,这些患者在2019年1月至2024年1月期间接受了ORB和夹子牵引的ESD治疗。分析穿孔可能的危险因素。中位ORB-ESD手术时间为40(IQR28-62)min,整体切除率和R0切除率分别为94.1%和84.0%,分别。119例患者中有16例发生穿孔(13.4%)。病变的大小,结肠右半或肠道皱褶上的病变,纤维化的程度,操作时间,手术经验与ORB-ESD穿孔相关(P<0.05)。多因素logistic回归分析显示,右半结肠病变(OR9.027;95%CI1.807~45.098;P=0.007)和肠道皱折病变(OR7.771;95%CI1.298~46.536;P=0.025)是ORB-ESD穿孔的独立危险因素。ORB-ESD是治疗纤维化结直肠病变的有效可行方法。需要对右侧结肠和整个肠丛的病变进行充分的术前评估,以减轻穿孔的风险。
    Endoscopic submucosal dissection (ESD) of fibrotic colorectal lesions is difficult and has a high complication rate. There are only a few reports on the utility of orthodontic rubber band (ORB) traction in reducing the difficulty of this procedure. This study aimed to investigate the risk factors for perforation when applying ORB traction during ESD of fibrotic colorectal lesions. We continuously collected the clinical data of 119 patients with fibrotic colorectal lesions who underwent ESD with ORB and clip traction between January 2019 and January 2024. Possible risk factors for perforation were analyzed. The median ORB-ESD operative time was 40 (IQR 28-62) min, and the en bloc and R0 resection rates were 94.1% and 84.0%, respectively. Perforation occurred in 16 of 119 patients (13.4%). The lesion size, lesion at the right half of the colon or across an intestinal plica, the degree of fibrosis, operation time, and the surgeon\'s experience were associated with perforation during ORB-ESD (P < 0.05). Multivariate logistic regression analysis showed that lesions in the right colon (OR 9.027; 95% CI 1.807-45.098; P = 0.007) and those across an intestinal plica (OR 7.771; 95% CI 1.298-46.536; P = 0.025) were independent risk factors for perforation during ORB-ESD. ORB-ESD is an effective and feasible approach to treat fibrotic colorectal lesions. Adequate preoperative evaluation is required for lesions in the right colon and across intestinal plicas to mitigate the risk of perforation.
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  • 文章类型: Journal Article
    目的:尽管内镜下切除直肠神经内分泌肿瘤(R-NENs)是一种有效的恶性潜能低的治疗方法,对于最推荐的内镜检查方法尚无共识.本研究旨在评估不同内镜治疗对低恶性潜能R-NENs的疗效和可接受性。
    方法:我们在数据库中搜索了使用内窥镜切除治疗R-NEN的研究。这些研究包括内窥镜粘膜切除术(EMR)等技术,内镜黏膜下剥离术(ESD),改良内镜黏膜切除术(EMRM),改良内镜黏膜下剥离术(ESDM),经肛门内窥镜显微手术(TEM)。评估的主要结果是组织学完全切除(HCR)。
    结果:总体而言,确定了38项回顾性研究(3040个R-NENs)。带帽内镜粘膜切除术(EMRC),内镜下黏膜结扎术(EMRL),ESD,ESDM,在实现HCR方面,TEM显示出比EMR更高的可切除性。内镜粘膜切除术,EMRC,EMRL,EMRP,EMRD,EMRU所需的操作时间比ESD短。内镜粘膜切除术,EMRC,ESDM,TEM的风险低于ESD。
    结论:关于具有低恶性潜能的<20mm的R-NENs,ESD可以用作主要处理。然而,如果有经济条件和医院设施的支持,TEM可能会更有效。关于R-NENs<16mm,具有低恶性潜能,EMRL可以用作主要治疗。关于R-NENs<10mm,具有低恶性潜能,EMRL,EMRC,ESD可以作为主要治疗方法。然而,考虑到运营困难和经济状况,EMRL和EMRC可能会更好。
    OBJECTIVE:  Although endoscopic resection is an effective treatment of rectal neuroendocrine neoplasms (R-NENs) with low malignant potential, there is no consensus on the most recommended endoscopic method. This study aimed to assess the efficacy and acceptability of different endoscopic treatments for R-NENs with low malignant potential.
    METHODS:  We searched databases for studies on treatments of R-NENs using endoscopic resection. These studies comprised techniques such as endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), modified endoscopic mucosal resection (EMRM), modified endoscopic submucosal dissection (ESDM), and transanal endoscopic microsurgery (TEM). The primary outcomes assessed were histological complete resection (HCR).
    RESULTS:  Overall, 38 retrospective studies (3040 R-NENs) were identified. Endoscopic mucosal resection with a cap (EMRC), endoscopic mucosal resection with ligation (EMRL), ESD, ESDM, and TEM demonstrated higher resectability than did EMR in achieving HCR. Endoscopic mucosal resection, EMRC, EMRL, EMRP, EMRD, and EMRU required shorter operation times than did ESD. Endoscopic mucosal resection, EMRC, ESDM, and TEM incurred lower risks than did ESD.
    CONCLUSIONS:  Regarding R-NENs <20 mm with low malignant potential, ESD could be used as the primary treatment. However, TEM may be more effective if supported by economic conditions and hospital facility. With respect to R-NENs <16 mm with low malignant potential, EMRL could be used as the primary treatment. In regard to R-NENs <10 mm with low malignant potential, EMRL, EMRC, and ESD could be used as the primary treatment. However, EMRL and EMRC might be better when operational difficulties and economic conditions were considered.
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  • 文章类型: Journal Article
    背景:这项研究调查并比较了疗效,安全,辐射暴露,经皮放射胃造口术(PRG)的两种方式的经济补偿:多层螺旋CT活检模式(MS-CTBM)引导和透视引导(FPRG)。目的是提供有关优化放射学辅助胃造口术程序的见解。
    方法:我们对2018年1月至2024年1月在单个中心进行的PRG程序进行了回顾性分析。根据所使用的成像方式将程序分为两组。我们比较了病人的人口统计,干预参数,并发症发生率,和程序时间。根据瑞士门诊医疗服务的关税结构(TARMED)评估了经济补偿。使用Fisher精确检验和Mann-WhitneyU检验确定统计学差异。
    结果:研究队列包括133例患者:55例MS-CTBM-PRG和78例FPRG。该队列包括35名女性和98名男性,平均年龄64.59岁(±11.91)。在有效剂量的方式之间观察到显着差异(MS-CTBM-PRG:10.95mSv±11.43vs.FPRG:0.169mSv±0.21,p<0.001)和手术时间(MS-CTBM-PRG:41.15min±16.14vs.FPRG:28.71分钟±16.03,p<0.001)。FPRG的主要并发症明显更频繁(10%vs.0%在MS-CTBM-PRG中,p=0.039,φ=0.214)。最初需要较高的单位数的MS-CTBM引导的PRG,以将手术持续时间减少10分钟。财务比较显示,只有4%的MS-CTBM引导的PRG获得了相当于最频繁的可比检查的报销,根据TARMED。
    结论:根据我们的回顾经验,单中心研究,使用MS-CTBM执行PRG,与FPRG相反,尽管主要并发症的发生率较低,但目前在具有挑战性的病例中是合理的。然而,需要进一步精心设计的前瞻性多中心研究来确定疗效,安全,以及这两种模式的成本效益。
    BACKGROUND: This study investigated and compared the efficacy, safety, radiation exposure, and financial compensation of two modalities for percutaneous radiologic gastrostomy (PRG): multislice computed tomography biopsy mode (MS-CT BM)-guided and fluoroscopy-guided (FPRG). The aim was to provide insights into optimizing radiologically assisted gastrostomy procedures.
    METHODS: We conducted a retrospective analysis of PRG procedures performed at a single center from January 2018 to January 2024. The procedures were divided into two groups based on the imaging modality used. We compared patient demographics, intervention parameters, complication rates, and procedural times. Financial compensation was evaluated based on the tariff structure for outpatient medical services in Switzerland (TARMED). Statistical differences were determined using Fisher\'s exact test and the Mann-Whitney U test.
    RESULTS: The study cohort included 133 patients: 55 with MS-CT BM-PRG and 78 with FPRG. The cohort comprised 35 women and 98 men, with a mean age of 64.59 years (±11.91). Significant differences were observed between the modalities in effective dose (MS-CT BM-PRG: 10.95 mSv ± 11.43 vs. FPRG: 0.169 mSv ± 0.21, p < 0.001) and procedural times (MS-CT BM-PRG: 41.15 min ± 16.14 vs. FPRG: 28.71 min ± 16.03, p < 0.001). Major complications were significantly more frequent with FPRG (10% vs. 0% in MS-CT BM-PRG, p = 0.039, φ = 0.214). A higher single-digit number of MS-CT BM-guided PRG was required initially to reduce procedure duration by 10 min. Financial comparison revealed that only 4% of MS-CT BM-guided PRGs achieved reimbursement equivalent to the most frequent comparable examination, according to TARMED.
    CONCLUSIONS: Based on our experience from a retrospective, single-center study, the execution of a PRG using MS-CT BM, as opposed to FPRG, is currently justified in challenging cases despite a lower incidence of major complications. However, further well-designed prospective multicenter studies are needed to determine the efficacy, safety, and cost-effectiveness of these two modalities.
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