METHODS: A comprehensive literature search comparing TR and OR in neonates was performed in accordance with the PRISMA statement (PROSPERO: CRD42020166588).
RESULTS: Fourteen studies were selected for quantitative analysis, including a total of 709 patients (TR: 308 cases, OR: 401 cases). The recurrence rate was higher [Odds ratio: 4.03, 95% CI (2.21, 7.36), p < 0.001] and operative times (minutes) were longer [Mean Difference (MD): 43.96, 95% CI (24.70, 63.22), p < 0.001] for TR compared to OR. A significant reduction in the occurrence of postoperative bowel obstruction was observed in TR (5.0%) compared to OR (14.8%) [Odds ratio: 0.42, 95% CI (0.20, 0.89), p = 0.02].
CONCLUSIONS: TR remains associated with higher recurrence rates and longer operative times. However, the reduced risk of postoperative bowel obstruction suggests potential long-term benefits. This study emphasizes the importance of meticulous patient selection for TR to mitigate detrimental effects on patients with severe disease.
方法:根据PRISMA声明(PROSPERO:CRD42020166588),对新生儿的TR和OR进行了全面的文献检索。
结果:选择了14项研究进行定量分析,包括总共709例患者(TR:308例,或:401例)。复发率较高[赔率:4.03,95%CI(2.21,7.36),p<0.001]和手术时间(分钟)更长[平均差(MD):43.96,95%CI(24.70,63.22),与OR相比,TR的p<0.001。与OR(14.8%)相比,TR(5.0%)观察到术后肠梗阻的发生率显着降低[赔率:0.42,95%CI(0.20,0.89),p=0.02]。
结论:TR仍然与较高的复发率和较长的手术时间相关。然而,术后肠梗阻风险降低提示潜在的长期益处.这项研究强调了精心选择TR患者以减轻对严重疾病患者的不利影响的重要性。