METHODS: One thousand one hundred thirty-nine non-small cell lung cancer patients who underwent pulmonary resection were retrospectively analyzed for risk factors of common postoperative complications.
RESULTS: In a multivariate analysis, male sex (P = 0.01), age ≥ 65 years (P < 0.01), coexistence of chronic obstructive pulmonary disease (COPD) (P < 0.01), upper lobe (P < 0.01), surgery time ≥ 155 min (P < 0.01), and presence of lymphatic invasion (P = 0.01) were significant factors for postoperative complication. Male sex (P < 0.01), age ≥ 65 years (P = 0.02), body mass index (BMI) < 21.68 (P < 0.01), coexistence of COPD (P = 0.02), and surgery time ≥ 155 min (P = 0.01) were significant factors for severe postoperative complication. Male sex (P = 0.01), BMI < 21.68 (P < 0.01), thoracoscopic surgery (P < 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative air leakage. Coexistence of COPD (P = 0.01) and coexistence of asthma (P < 0.01) were significant risk factors for postoperative atelectasis. Prognostic nutrition index (PNI) < 45.52 (P < 0.01), lobectomy or extended resection more than lobectomy (P = 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative arrhythmia.
CONCLUSIONS: Low BMI, thoracoscopic surgery, and longer surgery time were significant risk factors for postoperative air leakage. Coexistence of COPD and coexistence of asthma were significant risk factors for postoperative atelectasis. PNI, surgery time, and surgical procedure were revealed as risk factors of postoperative arrhythmia. Patients with these factors should be monitored for postoperative complication.
BACKGROUND: The Institutional Review Board of Kanazawa Medical University approved the protocol of this retrospective study (approval number: I392), and written informed consent was obtained from all patients.
方法:回顾性分析接受肺切除术治疗的99例非小细胞肺癌患者术后常见并发症的危险因素。
结果:在多变量分析中,男性(P=0.01),年龄≥65岁(P<0.01),慢性阻塞性肺疾病(COPD)的共存(P<0.01),上叶(P<0.01),手术时间≥155min(P<0.01),淋巴浸润(P=0.01)是术后并发症的重要因素。男性(P<0.01),年龄≥65岁(P=0.02),体重指数(BMI)<21.68(P<0.01),COPD共存(P=0.02),手术时间≥155min(P=0.01)是术后严重并发症的重要因素。男性(P=0.01),BMI<21.68(P<0.01),胸腔镜手术(P<0.01),手术时间≥155min(P<0.01)是术后漏气的危险因素。COPD共存(P=0.01)和哮喘共存(P<0.01)是术后肺不张的危险因素。预后营养指数(PNI)<45.52(P<0.01),肺叶切除术或扩大切除术多于肺叶切除术(P=0.01),手术时间≥155min(P<0.01)是术后心律失常的危险因素。
结论:低BMI,胸腔镜手术,手术时间较长是术后漏气的重要危险因素。COPD共存和哮喘共存是术后肺不张的重要危险因素。PNI,手术时间,和手术方式是术后心律失常的危险因素。有这些因素的患者应监测术后并发症。
背景:金泽医科大学机构审查委员会批准了这项回顾性研究的方案(批准号:I392),并获得所有患者的书面知情同意书.