Avoidant Restrictive Food Intake Disorder

避免限制性食物摄入障碍
  • 文章类型: Journal Article
    背景:避免限制性食物摄入障碍(ARFID)的特征是限制性饮食导致严重的医学和/或心理社会损害的模式(美国精神病学协会在精神障碍的诊断和统计手册中,美国精神病学协会,华盛顿,D.C.,2013).大多数关于ARFID的现有研究都采用定量方法来研究儿童和青少年。因此,成人接受ARFID的经验在研究中代表性不足.为了填补这个空白,本研究调查了DSM-5诊断为ARFID的成年人的生活经历.
    方法:参与者(n=9)包括从社交媒体广告招募的20-42岁成年女性(M=27,SD=6.2)。开放式,进行了半结构化访谈。使用解释现象学分析(IPA)对数据进行分析。
    结果:本研究将讨论IPA确定的三个总体主题之一:“安全与自由之间的权衡,“其中包括两个子主题:(a)确保食品安全,不受未知食品的影响;(c)渴望自由。这个总体主题探讨了ARFID对个人安全感和自由感的影响。
    结论:这项研究是对ARFID进行定性检查的少数研究之一,也是唯一使用IPA这样做的。研究结果为研究人员和临床医生提供了新的见解,这些研究人员和临床医生使用ARFID治疗成人,并希望在工作中增加对患者生活经验的考虑和理解。
    BACKGROUND: Avoidant restrictive food intake disorder (ARFID) is characterized as a pattern of restrictive eating leading to significant medical and/or psychosocial impairment (American Psychiatric Association in Diagnostic and statistical manual of mental disorders, American Psychiatric Association, Washington, D.C., 2013). Most existing research on ARFID utilizes quantitative methodologies to study children and adolescents. As a result, the experiences of adults with ARFID have been underrepresented in research. To fill this gap, the current study examines the lived experiences of adults with a DSM-5 diagnosis of ARFID.
    METHODS: Participants (n = 9) included adult women aged 20-42 (M = 27, SD = 6.2) recruited from social media advertising. Open-ended, semi-structured interviews were conducted. Data were analyzed using interpretative phenomenological analysis (IPA).
    RESULTS: One of three overarching themes identified by IPA will be discussed in this study: \"A tradeoff between safety and freedom,\" which consists of two subthemes: (a) Ensuring safety from food unknowns and (c) Longing for Freedom. This overarching theme explores the influence of ARFID on an individual\'s sense of safety and freedom.
    CONCLUSIONS: This study is one of few to qualitatively examine ARFID, and the only to do so using IPA. Findings offer novel insights relevant to researchers and clinicians who treat adults with ARFID and who wish to increase consideration and understanding of patient lived experience in their work.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:避免限制性食物摄入障碍(ARFID)是一种喂养和进食障碍,在儿童和年轻人(CYP)中具有已知的急性和长期身体健康并发症,通常会出现给儿科医生。
    目的:使用系统评价和荟萃分析指南的首选报告项目,系统地回顾已发表的关于CYP伴ARFID的身体健康并发症的文献。
    方法:对PubMed的系统搜索,Embase,WebofScience,PsycINFO和Cochrane图书馆于2024年2月14日进行。纳入报告CYP≤25年ARFID的身体健康并发症的研究。我们汇总了ARFID与健康对照或神经性厌食症(AN)的荟萃分析研究。
    结果:在搜索中发现的9058项研究中,我们纳入了132项研究。我们发现了低体重的证据,营养缺乏和骨密度低。带有ARFID的CYP可以在整个重量范围内呈现;但是,使用ARFID的CYP患者大部分在健康体重至体重不足的范围内.大多数研究报告了ARFID中正常范围的心率和血压,但是一些使用ARFID的CYP确实会出现心动过缓和低血压。使用ARFID的CYP的心率高于AN(加权平均差:12.93bpm;95%CI:8.65至17.21;n=685);异质性高(I2:81.33%)。
    结论:与ARFID相关的身体健康并发症范围广泛,需要临床考虑。许多使用ARFID的CYP体重不足,但仍有并发症。与AN相比,ARFID中发现的心血管并发症较少可能与慢性有关。
    CRD42022376866。
    BACKGROUND: Avoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder with known acute and longstanding physical health complications in children and young people (CYP) and commonly presents to paediatricians.
    OBJECTIVE: To systematically review the published literature on physical health complications in CYP with ARFID using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
    METHODS: A systematic search of PubMed, Embase, Web of Science, PsycINFO and Cochrane Library was performed on 14 February 2024. Studies reporting physical health complications in CYP ≤25 years with ARFID were included. We pooled studies for meta-analysis comparing ARFID with healthy controls or anorexia nervosa (AN).
    RESULTS: Of 9058 studies found in searches, we included 132 studies. We found evidence for low weight, nutritional deficiencies and low bone mineral density. CYP with ARFID can present across the weight spectrum; however, the majority of CYP with ARFID were within the healthy weight to underweight range. Most studies reported normal range heart rates and blood pressures in ARFID, but some CYP with ARFID do experience bradycardia and hypotension. CYP with ARFID had higher heart rates than AN (weighted mean difference: 12.93 bpm; 95% CI: 8.65 to 17.21; n=685); heterogeneity was high (I2: 81.33%).
    CONCLUSIONS: There is a broad range of physical health complications associated with ARFID requiring clinical consideration. Many CYP with ARFID are not underweight yet still have complications. Less cardiovascular complications found in ARFID compared with AN may be related to chronicity.
    UNASSIGNED: CRD42022376866.
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  • 文章类型: Journal Article
    食欲调节激素的破坏可能有助于避免性/限制性食物摄入障碍(ARFID)的发展和/或维持。以前没有研究评估过食欲释放肽或食欲减退肽YY(PYY)的空腹水平,在不同体重范围内,他们对ARFID青少年食物摄入量的反应轨迹也没有。我们在127名男性和女性中测量了空腹和餐后(餐后30、60、120分钟)的ghrelin和PYY水平。我们使用潜在生长曲线分析来检查ARFID和HC之间ghrelin和PYY轨迹的差异。与HC相比,ARFID中ghrelin的空腹水平没有差异。在ARFID中,在餐后的第一个小时,ghrelin水平比HC下降得更缓慢(p=0.005),但在用餐后60到120分钟之间继续下降,而HC趋于稳定(p=0.005)。禁食和PYY轨迹在各组之间没有差异。调整BMI百分位数(M(SD)ARFID=37(35);M(SD)HC=53(26);p=.006)或测试进餐期间消耗的卡路里(M(SD)ARFID=294(118);M(SD)HC=384(48);p<.001)后,结果没有变化。这些数据突出了在使用ARFID的年轻人中进行测试餐后ghrelin的独特轨迹。未来的研究应该检查生长素释放肽功能障碍作为ARFID的病因或维持因素。
    Disruptions in appetite-regulating hormones may contribute to the development and/or maintenance of avoidant/restrictive food intake disorder (ARFID). No study has previously assessed fasting levels of orexigenic ghrelin or anorexigenic peptide YY (PYY), nor their trajectory in response to food intake among youth with ARFID across the weight spectrum. We measured fasting and postprandial (30, 60, 120 minutes post-meal) levels of ghrelin and PYY among 127 males and females with full and subthreshold ARFID (n = 95) and healthy controls (HC; n = 32). We used latent growth curve analyses to examine differences in the trajectories of ghrelin and PYY between ARFID and HC. Fasting levels of ghrelin did not differ in ARFID compared to HC. Among ARFID, ghrelin levels declined more gradually than among HC in the first hour post meal (p =.005), but continued to decline between 60 and 120 minutes post meal, whereas HC plateaued (p =.005). Fasting and PYY trajectory did not differ by group. Findings did not change after adjusting for BMI percentile (M(SD)ARFID = 37(35); M(SD)HC = 53(26); p =.006) or calories consumed during the test meal (M(SD)ARFID = 294(118); M(SD)HC = 384 (48); p <.001). These data highlight a distinct trajectory of ghrelin following a test meal in youth with ARFID. Future research should examine ghrelin dysfunction as an etiological or maintenance factor of ARFID.
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  • 文章类型: Journal Article
    避免性限制性食物摄入障碍(ARFID)是一种饮食障碍,其特征在于持续的营养和/或能量摄入不足。ARFID,之前被称为“选择性进食障碍”,最近在DSM-5中引入,作为先前诊断的替代和扩展。患有ARFID的个体可能会由于基于食物的感官特征或与饮食的任何不利后果相关的避免而限制食物种类和摄入量,而不打算减肥和关注身体形象。对回避和限制性饮食的有限理解对有效治疗和管理提出了挑战,直接影响儿童和青少年的生长发育。ARFID神经生物学概念尚未明确定义为营养学家的临床实践,从而阻碍筛查并阻碍治疗建议的发展。这篇叙述性综述为查阅病理生理学提供了有用的实用信息,神经生物学,临床特征,为寻求提高对这种疾病的临床知识和管理的医疗保健专业人员进行评估和治疗。
    避免限制性食物摄入障碍(ARFID)是一种饮食障碍,其特征在于持续的营养和/或能量摄入不足。使用ARFID的个人表现出有限的食物摄入量和品种,通常由于缺乏饮食,没有减肥的主要目标。对回避和限制性饮食的有限理解在有效治疗和管理方面提出了挑战,直接影响儿童和青少年的生长发育,以及他们的营养和社会心理健康。ARFID是一个相对较新的诊断分类,代表一个新兴的研究领域。诊断标准的确定和对这一领域新知识的追求最近才开始。因此,评估工具和治疗策略仍在开发和验证过程中。这篇叙事综述使用三维模型探索了ARFID的神经生物学观点,检查其病因和危险因素,评估的临床筛查和评估工具,讨论了常见的临床并发症,并提供不同类型的营养,行为,以及用于ARFID治疗的药物干预措施。
    Avoidant restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent insufficient nutritional and/or energy intake. ARFID, before referred to as \"selective eating disorder\", was introduced recently in the DSM-5 as a replacement for and expansion of the previous diagnosis. Individuals with ARFID may limit food variety and intake due to avoidance based on the sensory characteristics of the food or related to any adverse consequences of eating without the intention of losing weight and concerns of body image. The limited understanding of avoidant and restrictive eating poses challenges to effective treatment and management, impacting directly on the growth and development of children and adolescents. The ARFID neurobiological concept has not yet been clearly defined to clinical practice for nutritionists, thereby hindering screening and impeding the development of treatment recommendations. This narrative review provide useful practical information to consult the pathophysiology, the neurobiology, the clinical features, the assessment and the treatment for healthcare professionals seeking to enhance their clinical knowledge and management of this disorder.
    Avoidant restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent insufficient nutritional and/or energy intake. Individuals with ARFID exhibit limited food intake and variety, often due to a lack in eating, without the primary goal of weight loss. The limited understanding of avoidant and restrictive eating poses challenges in terms of effective treatment and management, which directly impacts the growth and development of children and adolescents, as well as their nutrition and psychosocial well-being. ARFID is a relatively recent diagnostic classification, representing a burgeoning field of study. The identification of diagnostic criteria and the pursuit of new knowledge in this area have only recently begun. Consequently, assessment tools and treatment strategies are still in the process of development and validation. This narrative review explored the neurobiological perspective of ARFID using the three-dimensional model, examined its etiology and risk factors, evaluated clinical screening and evaluation tools, discussed common clinical complications, and presented different types of nutritional, behavioural, and pharmacological interventions used in ARFID treatment.
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  • 文章类型: Journal Article
    患有肠衰竭的婴儿和儿童面临儿科喂养障碍的风险,这挑战了他们的口服喂养发展。本文探讨了这些挑战,并提供了几种实用的策略,可用于多学科护理团队和家庭护理人员,以帮助支持这些儿童的口服喂养的发展,并最终导致他们获得肠道自主权。
    Infants and children with intestinal failure are at risk for pediatric feeding disorders, which challenge their oral feeding development. This article explores these challenges and offers several practical strategies that can be used by multidisciplinary care teams and at-home caregivers to help support the development of oral feeding in these children and eventually lead to their attaining enteral autonomy.
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    炎症性肠病(IBD)患者认为饮食在其疾病的发病机理和症状的恶化中起着重要作用。他们经常采取限制性饮食,可能导致营养不良,焦虑,和压力。最近的研究发现IBD与饮食失调之间存在相关性,如神经性厌食症和ARFID(避免限制性食品摄入障碍)。这些研究都没有报道与神经性矫正相关,这是对健康和天然食物的痴迷。这项研究的目的是评估IBD患者发生神经性矫正的风险。共招募了158名连续受试者,包括113例IBD患者和45例对照。使用标准化的Donini问卷ORTO-15评估矫正性厌食症的风险,收集临床和人口统计学数据。结果显示,IBD患者患神经性正食症的风险为77%。这显著高于对照组中观察到的47%。在IBD患者中,矫正的风险与较低的BMI相关,至少在30岁以上的患者中,它也与30岁以下患者的婚姻状况有关。总之,许多IBD患者患神经性正食症的风险增加,这可能会对他们的心理健康和社会领域产生负面影响,使他们面临营养缺乏的高风险,影响他们的整体生活质量。需要进一步的高质量研究来评估矫形症的临床影响及其与临床特征和分类进食障碍的相关性。
    Patients with inflammatory bowel disease (IBD) believe that diet plays a significant role in the pathogenesis of their disease and the exacerbation of their symptoms. They often adopt restrictive diets that can lead to malnutrition, anxiety, and stress. Recent studies have found a correlation between IBD and eating disorders, such as anorexia nervosa and ARFID (Avoidant Restrictive Food Intake Disorder). None of these studies report an association with orthorexia nervosa, which is an obsession with healthy and natural foods. The aim of this study was to assess the risk of orthorexia nervosa in patients with IBD. A total of 158 consecutive subjects were recruited, including 113 patients with IBD and 45 controls. The standardized Donini questionnaire ORTO-15 was administered to assess the risk of orthorexia, and clinical and demographic data were collected. The results showed that patients with IBD had a risk of developing orthorexia nervosa of 77%. This was significantly higher than the 47% observed in the control group. In the patients with IBD, the risk of orthorexia was associated with a lower BMI, at least in patients older than 30 years, and it was also associated with marital status in patients younger than 30. In conclusion, many patients with IBD are at increased risk of developing orthorexia nervosa, which may have a negative impact on their psychological wellbeing and social sphere, expose them to a high risk of nutritional deficiencies, and affect their overall quality of life. Further high-quality studies are needed to assess the clinical impact of orthorexia and its correlation with clinical features and classified eating disorders.
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  • 文章类型: Journal Article
    背景:避免限制性食物摄入障碍(ARFID)是添加到DSM-5中的一种新诊断,其特征是病理性饮食习惯而没有身体形象障碍。先前的研究结果表明,高度完美主义和低水平的自尊心与一般饮食失调之间存在普遍关联。然而,特别是关于ARFID的研究很少。随后,虽然自尊被认为可以缓和完美主义和一般饮食失调之间的联系,这项研究旨在探索同样的适度,但特别是ARFID。
    方法:对于本研究,从黎巴嫩全国招募了515名黎巴嫩成年人,其中60.1%为女性。阿拉伯语版本的三大完美主义量表-缩写形式(BTPS-SF)用于测量自我批评,僵化和自恋性完美主义;使用避免性/限制性食物摄入障碍屏幕(NIAS)对ARFID变量进行评分;阿拉伯语-单项自尊(A-SISE)是用于衡量自尊的量表。
    结果:在不同的完美主义类型中,自尊可以缓解自恋完美主义与ARFID之间的关联(Beta=-0.22;p=.006)。在低点(Beta=0.77;p<.001),中等(β=0.56;p<.001)和高(β=0.36;p=.001)的自尊水平,较高的自恋完美主义与较高的ARFID评分显著相关.
    结论:这项研究揭示了一些重要的临床意义,强调了需要干预措施来帮助增强高度完美主义和ARFID患者的自尊。这项研究表明,临床医生和医疗保健专业人员应该更多地关注影响ARFID样症状发展和维持的风险因素。
    BACKGROUND: Avoidant Restrictive Food Intake Disorder (ARFID) is a new diagnosis added to the DSM-5 characterized by pathological eating habits without body image disturbances. Previous findings demonstrated a general association between high levels of perfectionism and low levels of self-esteem in association with general eating disorders. However, research is scant when it comes to ARFID specifically. Subsequently, although self-esteem is seen to moderate the association between perfectionism and general eating disorders, this research study aims to explore the same moderation but with ARFID specifically.
    METHODS: For this study, 515 Lebanese adults from the general Lebanese population were recruited from all over Lebanon, 60.1% of which were females. The Arabic version of the Big Three Perfectionism Scale- Short Form (BTPS-SF) was used to measure self-critical, rigid and narcissistic perfectionism; the Avoidant/Restrictive Food Intake Disorder screen (NIAS) was used to score the ARFID variable; the Arabic-Single Item Self-Esteem (A-SISE) was the scale used to measure self-esteem.
    RESULTS: Across the different perfectionism types, self-esteem was seen to moderate the association between narcissistic perfectionism and ARFID (Beta = - 0.22; p =.006). At low (Beta = 0.77; p <.001), moderate (Beta = 0.56; p <.001) and high (Beta = 0.36; p =.001) levels of self-esteem, higher narcissistic perfectionism was significantly associated with higher ARFID scores.
    CONCLUSIONS: This study brought to light some crucial clinical implications that highlight the need for interventions that help in the enhancement of self-esteem in patients with high perfectionism and ARFID. This study suggests that clinicians and healthcare professionals should focus more on risk factors influencing the development and maintenance of ARFID-like symptoms.
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    避免限制性食品摄入障碍(ARFID)于2013年首次被列为诊断类别,在过去的10年中已被国际饮食失调界采用。虽然对这些困难的认识提高了认同感,对临床服务的需求和有力的倡导,ARFID的异质性对饮食失调临床医师和研究者提出了独特的挑战.本评论旨在反思其中一些挑战,特别关注通过饮食失调镜片观察ARFID的风险。这包括文献中的潜在偏见,因为最近的研究是在专门的儿童和青少年饮食失调诊所环境中进行的。质疑研究结果对受ARFID影响的广泛个体的普遍性。我们还考虑是否主要通过饮食失调的镜头来观看ARFID,这是否会使我们的多学科喂养同事可能带来的有效技能范围眨眼。饮食失调领域可能会有机会导航ARFID的治疗途径,包括更多与多学科同事合作,将ARFID治疗中使用的技能转移给进食障碍患者的能力,最值得注意的是,有机会为ARFID患者及其家人提供更有效的治疗和服务途径。然而,只有当饮食失调的临床医生和研究人员走出目前的孤岛时,这些机会才能实现。
    Avoidant Restrictive Food Intake Disorder (ARFID) was first included as a diagnostic category in 2013, and over the past 10 years has been adopted by the international eating disorder community. While greater awareness of these difficulties has increased identification, demand and enabled advocacy for clinical services, the heterogeneous nature of ARFID poses unique challenges for eating disorder clinicians and researchers. This commentary aims to reflect on some of these challenges, focussing specifically on the risk of viewing ARFID through an eating disorder lens. This includes potential biases in the literature as most recent research has been conducted in specialist child and adolescent eating disorder clinic settings, bringing in to question the generalisability of findings to the broad spectrum of individuals affected by ARFID. We also consider whether viewing ARFID predominantly through an eating disorder lens risks us as a field being blinkered to the range of effective skills our multi-disciplinary feeding colleagues may bring. There are opportunities that may come with the eating disorder field navigating treatment pathways for ARFID, including more joined up working with multi-disciplinary colleagues, the ability to transfer skills used in ARFID treatment to individuals with eating disorder presentations, and most notably an opportunity to provide more effective treatment and service pathways for individuals with ARFID and their families. However, these opportunities will only be realised if eating disorder clinicians and researchers step out of their current silos.
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  • 文章类型: Journal Article
    素食主义是一种日益增长的趋势,食物恐惧症和神经性矫正症可能成为实现健康素食饮食的障碍。这项研究的目的是比较食物恐惧症的水平,焦虑,以及素食者和杂食者中正食症的健康和病理方面。此外,这项研究旨在确定食物恐惧症之间的关系,焦虑,和矫正症。在这个横断面的在线调查中,共有324名素食主义者和455名杂食者参加。问卷由四个部分组成:社会人口统计学,生活方式,和健康相关的特征,食物恐惧症量表(FNS),TeruelOrthorexia量表(TOS),和广义焦虑症-7量表。与杂食动物相比,素食者表现出更低的FNS评分(p<0.001)和更高的健康正交性评分(p<0.001)。两组之间的焦虑评分无差异(p>0.05)。回归分析表明,较高的食物恐惧症(OR:0.953,95%CI:0.937-0.968)和TOS-OrNe评分(OR:0.946,95%CI:0.901-0.993)与较低的素食几率相关。相反,较高的TOS-HeOr评分(OR:1.135,95%CI:1.096-1.176)与采用素食的可能性增加有关.此外,FNS和GAD-7评分均与TOS-HeOR呈负相关(分别为r=-0.124,p<0.001和r=-0.129p<0.001),与TOS-OrNe呈正相关(r=0.106,p<0.001,r=0.146,p<0.001)。总之,与杂食动物相比,素食者表现出较低的食物恐惧症和对健康饮食的更大兴趣。此外,矫正性厌食症与食物恐惧症和焦虑的两个维度之间的明显相关性为矫正性厌食症的二维性质提供了支持。
    Vegetarianism is a growing trend, and food neophobia and orthorexia nervosa could act as barriers to achieving a healthy vegetarian diet. The aim of this study is to compare the levels of food neophobia, anxiety, and both healthy and pathological aspects of orthorexia among vegetarians and omnivores. Additionally, the study aims to identify the relationships between food neophobia, anxiety, and orthorexia. In this cross-sectional online survey, a total of 324 vegetarian and 455 omnivores adults participated. The questionnaire consisted of four sections: sociodemographic, lifestyle, and health-related characteristics, the Food Neophobia Scale (FNS), the Teruel Orthorexia Scale (TOS), and the Generalized Anxiety Disorders-7 Scale. Vegetarians exhibited lower FNS scores (p < 0.001) and had higher healthy orthorexic scores (p < 0.001) than omnivores. There were no differences between groups for anxiety scores (p > 0.05). Regression analysis indicated that higher food neophobia (OR: 0.953, 95% CI:0.937-0.968) and TOS-OrNe scores (OR: 0.946, 95% CI: 0.901-0.993) were associated with lower odds of following a vegetarian diet. Conversely, higher TOS-HeOr scores (OR: 1.135, 95% CI:1.096-1.176) were linked to an increased likelihood of adopting a vegetarian diet. Furthermore, both FNS and GAD-7 scores showed negative correlations with TOS-HeOR (r = -0.124, p < 0.001 and r = -0.129 p < 0.001, respectively), and positive correlations with TOS-OrNe (r = 0.106, p < 0.001 and r = 0.146, p < 0.001). In conclusion, vegetarians exhibit lower levels of food neophobia and a greater interest in healthy eating than omnivores. Additionally, the distinct correlation between two dimensions of orthorexia and food neophobia and anxiety provides support for the two-dimensional nature of orthorexia.
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