PDF(Pubmed)
Abstract：
Patients with inflammatory bowel disease (IBD) believe that diet plays a significant role in the pathogenesis of their disease and the exacerbation of their symptoms. They often adopt restrictive diets that can lead to malnutrition, anxiety, and stress. Recent studies have found a correlation between IBD and eating disorders, such as anorexia nervosa and ARFID (Avoidant Restrictive Food Intake Disorder). None of these studies report an association with orthorexia nervosa, which is an obsession with healthy and natural foods. The aim of this study was to assess the risk of orthorexia nervosa in patients with IBD. A total of 158 consecutive subjects were recruited, including 113 patients with IBD and 45 controls. The standardized Donini questionnaire ORTO-15 was administered to assess the risk of orthorexia, and clinical and demographic data were collected. The results showed that patients with IBD had a risk of developing orthorexia nervosa of 77%. This was significantly higher than the 47% observed in the control group. In the patients with IBD, the risk of orthorexia was associated with a lower BMI, at least in patients older than 30 years, and it was also associated with marital status in patients younger than 30. In conclusion, many patients with IBD are at increased risk of developing orthorexia nervosa, which may have a negative impact on their psychological wellbeing and social sphere, expose them to a high risk of nutritional deficiencies, and affect their overall quality of life. Further high-quality studies are needed to assess the clinical impact of orthorexia and its correlation with clinical features and classified eating disorders.
摘要：
炎症性肠病（IBD）患者认为饮食在其疾病的发病机理和症状的恶化中起着重要作用。他们经常采取限制性饮食，可能导致营养不良，焦虑,和压力。最近的研究发现IBD与饮食失调之间存在相关性，如神经性厌食症和ARFID（避免限制性食品摄入障碍）。这些研究都没有报道与神经性矫正相关，这是对健康和天然食物的痴迷。这项研究的目的是评估IBD患者发生神经性矫正的风险。共招募了158名连续受试者,包括113例IBD患者和45例对照。使用标准化的Donini问卷ORTO-15评估矫正性厌食症的风险，收集临床和人口统计学数据。结果显示，IBD患者患神经性正食症的风险为77%。这显著高于对照组中观察到的47%。在IBD患者中,矫正的风险与较低的BMI相关，至少在30岁以上的患者中，它也与30岁以下患者的婚姻状况有关。总之,许多IBD患者患神经性正食症的风险增加，这可能会对他们的心理健康和社会领域产生负面影响，使他们面临营养缺乏的高风险，影响他们的整体生活质量。需要进一步的高质量研究来评估矫形症的临床影响及其与临床特征和分类进食障碍的相关性。
