Avoidant Restrictive Food Intake Disorder

避免限制性食物摄入障碍
  • 文章类型: Journal Article
    自闭症和饮食失调的高并发性已经确立,包括那些避免限制性食物摄入障碍(ARFID)。因此,重要的是要考虑自闭症,并在人们参加饮食失调服务时确定可能的自闭症,以确定是否需要进一步评估,支持临床制定,并在干预期间进行适当的调整。本文探讨了一种经过验证的自闭症筛查措施的实用性,AQ-10在向门诊饮食失调诊所就诊以评估可能的ARFID的儿童和青少年人群中。超过19个月,对335名年轻人进行了评估,246个有4至17岁儿童的家庭完成了AQ-10的三个版本之一(儿童,青少年,和成人),作为一系列常规管理的预评估问卷的一部分。结果表明,80.2%(n=69)的自闭症诊断评分高于临床阈值≥6(M=7.2,SD=1.9),43.9%(n=43)被查询为自闭症患者得分高于临床阈值(M=5.2,SD=2.5),和6.5%(n=4)的非自闭症个体得分高于临床阈值(M=2.8,SD=1.8)。此外,AQ-10在所有年龄组和性别中都令人满意地区分了已知自闭症诊断的患者和非自闭症患者。我们得出的结论是,AQ-10除了全面的临床评估和临床判断,是一个有用的筛选工具,可以支持临床医生确定适当的向前转介自闭症评估,辅助临床配方,并在ARFID干预期间考虑适当的适应和合理的调整。
    The high co-occurrence of autism and eating disorders is well established, including for those with Avoidant Restrictive Food Intake Disorder (ARFID). It is therefore important to consider autism and identify possible autism when people present to eating disorder services to ascertain whether further assessment is indicated, to support clinical formulation and to make appropriate adaptations during interventions. This paper explores the utility of a validated autism screening measure, the AQ-10, in a population of children and adolescents who presented to an outpatient eating disorders clinic for an assessment of possible ARFID. Over 19 months, 335 young people were assessed and 246 families with children aged between 4 and 17 years completed one of three versions of the AQ-10 (Child, Adolescent, and Adult), as part of a battery of routinely administered pre-assessment questionnaires. Results indicated that 80.2% (n = 69) of those with an existing autism diagnosis scored above clinical threshold of ≥6 (M = 7.2, SD = 1.9), 43.9% (n = 43) of those queried to be autistic scored above clinical threshold (M = 5.2, SD = 2.5), and 6.5% (n = 4) of non-autistic individuals scored above clinical threshold (M = 2.8, SD = 1.8). Additionally, the AQ-10 satisfactorily discriminated between those with a known autism diagnosis and those who are not autistic across all age groups and sex. We conclude that the AQ-10, alongside a comprehensive clinical assessment and clinical judgment, is a useful screening tool that can support clinicians to identify appropriate onward referrals for autism assessments, aid clinical formulation, and consider appropriate adaptations and reasonable adjustments during ARFID interventions.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    食物恐惧症(FN)降低了营养充足性和多样性,这对儿童的健康和福祉构成了重大关注。我们描述了8岁儿童的FN得分,并在45个月时检查了其与营养相关行为的关联在新西兰成长队列中(n=4,621)。使用食物恐惧症量表(FNS)估计FN。使用独立样本的t检验和ANOVA比较变量类别之间的平均FNS得分。使用多元线性回归检查8年时的FNS评分与45个月时的营养相关行为之间的关联。平均(标准差)FN评分为46.2(15.2),性别差异具有统计学意义(男孩=47.6(15.7),女孩=43.8(14.2),p=<0.001)。对于所有的孩子,在根据母乳喂养持续时间和社会人口统计学特征调整的模型中:有时和从不/几乎从不与父母相同的食物的儿童,得分,平均而言,FNS高出5.8分和11分(与那些总是/几乎总是这样做的人相比);偶尔/从未发现用餐时间令人愉悦的儿童在FNS中平均得分低3.6分(与大多数/经常相比);在用餐时间总是/几乎总是开着电视的儿童在FNS中平均得分高2.7分(与从不/几乎从不)。与在进餐时间大部分/经常有时间与他人交谈的孩子相比,那些从未/偶尔做过的人在FNS总体上(高1.46分)和女孩中(高1.73分)的平均得分较高。这些发现支持国家儿童食品和营养指南中的饮食行为声明,强调早期接触食物多样性,限制进餐时间的分心,并承认父母的角色塑造塑造了儿童的营养相关行为。需要尽早采取预防性干预措施,以减少儿童早期和中期的FN。
    Food neophobia (FN) reduces nutritional adequacy and variety which poses a significant concern for children\'s health and well-being We described the FN scores among 8-year-olds and examined its associations with nutrition-related behaviors at 45 months within the Growing Up in New Zealand cohort (n = 4621). FN was estimated using the Food Neophobia Scale (FNS). Mean FNS scores between variable categories were compared using t-tests for independent samples and ANOVA. Associations between FNS scores at 8 years and nutrition-related behaviors at 45-months were examined using multivariate linear regression. The mean (standard deviation) FN score was 46.2 (15.2) with statistically significant differences by sex (boys = 47.6 (15.7), girls = 43.8 (14.2), p=<0.001). For all children, in models adjusted by breastfeeding duration and sociodemographic characteristics: children who sometimes and never/almost never ate the same foods as their parents, scored, on average, 5.8 and 11 points higher in the FNS (versus those who did always/almost always); children who occasionally/never found mealtimes enjoyable scored on average 3.6 points lower in the FNS (versus mostly/quite often); children who always/almost always had the television on during mealtimes scored on average 2.7 higher in the FNS (versus never/almost never). In comparison to children who mostly/quite often had time to talk to others during mealtimes, those who never/occasionally did it scored on average higher points in the FNS overall (1.46 points higher) and within girls (1.73 points higher). These findings support the eating behavior statements in the National Children\'s Food and Nutrition Guidelines, which emphasize early exposure to food variety, limiting mealtime distractions, and acknowledge that parental role modeling shapes children\'s nutrition-related behaviors. Early adoption of preventative interventions for reducing FN in early and middle childhood are needed.
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  • 文章类型: Journal Article
    背景:避免限制性食物摄入障碍(ARFID)的特征是限制性饮食导致严重的医学和/或心理社会损害的模式(美国精神病学协会在精神障碍的诊断和统计手册中,美国精神病学协会,华盛顿,D.C.,2013).大多数关于ARFID的现有研究都采用定量方法来研究儿童和青少年。因此,成人接受ARFID的经验在研究中代表性不足.为了填补这个空白,本研究调查了DSM-5诊断为ARFID的成年人的生活经历.
    方法:参与者(n=9)包括从社交媒体广告招募的20-42岁成年女性(M=27,SD=6.2)。开放式,进行了半结构化访谈。使用解释现象学分析(IPA)对数据进行分析。
    结果:本研究将讨论IPA确定的三个总体主题之一:“安全与自由之间的权衡,“其中包括两个子主题:(a)确保食品安全,不受未知食品的影响;(c)渴望自由。这个总体主题探讨了ARFID对个人安全感和自由感的影响。
    结论:这项研究是对ARFID进行定性检查的少数研究之一,也是唯一使用IPA这样做的。研究结果为研究人员和临床医生提供了新的见解,这些研究人员和临床医生使用ARFID治疗成人,并希望在工作中增加对患者生活经验的考虑和理解。
    BACKGROUND: Avoidant restrictive food intake disorder (ARFID) is characterized as a pattern of restrictive eating leading to significant medical and/or psychosocial impairment (American Psychiatric Association in Diagnostic and statistical manual of mental disorders, American Psychiatric Association, Washington, D.C., 2013). Most existing research on ARFID utilizes quantitative methodologies to study children and adolescents. As a result, the experiences of adults with ARFID have been underrepresented in research. To fill this gap, the current study examines the lived experiences of adults with a DSM-5 diagnosis of ARFID.
    METHODS: Participants (n = 9) included adult women aged 20-42 (M = 27, SD = 6.2) recruited from social media advertising. Open-ended, semi-structured interviews were conducted. Data were analyzed using interpretative phenomenological analysis (IPA).
    RESULTS: One of three overarching themes identified by IPA will be discussed in this study: \"A tradeoff between safety and freedom,\" which consists of two subthemes: (a) Ensuring safety from food unknowns and (c) Longing for Freedom. This overarching theme explores the influence of ARFID on an individual\'s sense of safety and freedom.
    CONCLUSIONS: This study is one of few to qualitatively examine ARFID, and the only to do so using IPA. Findings offer novel insights relevant to researchers and clinicians who treat adults with ARFID and who wish to increase consideration and understanding of patient lived experience in their work.
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  • 文章类型: Journal Article
    背景:避免限制性食物摄入障碍(ARFID)是一种喂养和进食障碍,在儿童和年轻人(CYP)中具有已知的急性和长期身体健康并发症,通常会出现给儿科医生。
    目的:使用系统评价和荟萃分析指南的首选报告项目,系统地回顾已发表的关于CYP伴ARFID的身体健康并发症的文献。
    方法:对PubMed的系统搜索,Embase,WebofScience,PsycINFO和Cochrane图书馆于2024年2月14日进行。纳入报告CYP≤25年ARFID的身体健康并发症的研究。我们汇总了ARFID与健康对照或神经性厌食症(AN)的荟萃分析研究。
    结果:在搜索中发现的9058项研究中,我们纳入了132项研究。我们发现了低体重的证据,营养缺乏和骨密度低。带有ARFID的CYP可以在整个重量范围内呈现;但是,使用ARFID的CYP患者大部分在健康体重至体重不足的范围内.大多数研究报告了ARFID中正常范围的心率和血压,但是一些使用ARFID的CYP确实会出现心动过缓和低血压。使用ARFID的CYP的心率高于AN(加权平均差:12.93bpm;95%CI:8.65至17.21;n=685);异质性高(I2:81.33%)。
    结论:与ARFID相关的身体健康并发症范围广泛,需要临床考虑。许多使用ARFID的CYP体重不足,但仍有并发症。与AN相比,ARFID中发现的心血管并发症较少可能与慢性有关。
    CRD42022376866。
    BACKGROUND: Avoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder with known acute and longstanding physical health complications in children and young people (CYP) and commonly presents to paediatricians.
    OBJECTIVE: To systematically review the published literature on physical health complications in CYP with ARFID using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
    METHODS: A systematic search of PubMed, Embase, Web of Science, PsycINFO and Cochrane Library was performed on 14 February 2024. Studies reporting physical health complications in CYP ≤25 years with ARFID were included. We pooled studies for meta-analysis comparing ARFID with healthy controls or anorexia nervosa (AN).
    RESULTS: Of 9058 studies found in searches, we included 132 studies. We found evidence for low weight, nutritional deficiencies and low bone mineral density. CYP with ARFID can present across the weight spectrum; however, the majority of CYP with ARFID were within the healthy weight to underweight range. Most studies reported normal range heart rates and blood pressures in ARFID, but some CYP with ARFID do experience bradycardia and hypotension. CYP with ARFID had higher heart rates than AN (weighted mean difference: 12.93 bpm; 95% CI: 8.65 to 17.21; n=685); heterogeneity was high (I2: 81.33%).
    CONCLUSIONS: There is a broad range of physical health complications associated with ARFID requiring clinical consideration. Many CYP with ARFID are not underweight yet still have complications. Less cardiovascular complications found in ARFID compared with AN may be related to chronicity.
    UNASSIGNED: CRD42022376866.
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  • 文章类型: Journal Article
    背景:挑食(PE)在儿童早期很常见,在1到5岁之间达到峰值。然而,体育可能会持续超过这一规范时期,并对健康和社会心理功能构成威胁。避免/限制性食物摄入障碍(ARFID)涉及由食欲驱动的限制性饮食,偏好/选择性,和/或害怕吃东西,导致严重的医学和/或心理障碍。这项回顾性研究检查了儿童早期PE发作/持续时间与ARFID饮食限制和症状之间的关系。
    方法:6-17岁(N=437)儿童的父母完成了一项关于他们孩子饮食行为的调查,包括九项ARFID屏幕(NIAS)和有关PE发病和影响的问题。然后根据PE发病(5岁之前或之后)和持续时间将儿童分为几组:从不挑剔,规范挑剔,持续挑剔,和迟发性挑剔。
    结果:两组的平均NIAS分量表(挑食,NIAS-PE;食欲,NIAS-A;恐惧,NIAS-F)和总分(NIAS-T)。Tukey事后测试发现,持久性PE的NIAS-PE明显更高,NIAS-A,和NIAS-T得分比never或规范性PE(所有p<0.05)。卡方检验发现,持久性PE比所有其他组更有可能认可ARFID标准。
    结论:本研究的研究结果表明,与规范且从不PE相比,持续超过规范期或在规范期之后确定的PE与ARFID症状升高有关。持续PE会增加PE和其他ARFID饮食限制造成损害的风险。考虑到与ARFID相关的健康和社会心理风险,有必要对这一群体进行早期识别和干预.
    BACKGROUND: Picky eating (PE) is common in early childhood, peaking between ages 1 and 5 years. However, PE may persist beyond this normative period and pose threats to health and psychosocial functioning. Avoidant/restrictive food intake disorder (ARFID) involves restrictive eating driven by appetite, preference/selectivity, and/or fear of eating, leading to significant medical and/or psychosocial impairment. This retrospective study examined the relation between early childhood PE onset/duration and ARFID eating restrictions and symptoms.
    METHODS: Parents of children ages 6-17 (N = 437) completed a survey about their child\'s eating behavior, including the Nine-item ARFID Screen (NIAS) and questions about PE onset and impacts. Children were then categorized into groups based on PE onset (before or after age 5) and duration: never picky, normative picky, persistent picky, and late-onset picky.
    RESULTS: The groups differed (all p < .05) in mean NIAS subscales (picky eating, NIAS-PE; appetite, NIAS-A; fear, NIAS-F) and total scores (NIAS-T). Tukey post-hoc tests found that persistent PEs had significantly higher NIAS-PE, NIAS-A, and NIAS-T scores than never or normative PEs (all p < .05). Chi-Square tests found that persistent PEs were significantly more likely than all other groups to endorse ARFID criteria.
    CONCLUSIONS: Findings from this study suggest that PE that persists beyond or is identified after the normative period is associated with elevated ARFID symptoms compared to normative and never PEs. Persistent PE increases risk of impairment from PE and other ARFID eating restrictions. Given the health and psychosocial risks associated with ARFID, early identification and intervention for this group is warranted.
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  • 文章类型: Journal Article
    食欲调节激素的破坏可能有助于避免性/限制性食物摄入障碍(ARFID)的发展和/或维持。以前没有研究评估过食欲释放肽或食欲减退肽YY(PYY)的空腹水平,在不同体重范围内,他们对ARFID青少年食物摄入量的反应轨迹也没有。我们在127名男性和女性中测量了空腹和餐后(餐后30、60、120分钟)的ghrelin和PYY水平。我们使用潜在生长曲线分析来检查ARFID和HC之间ghrelin和PYY轨迹的差异。与HC相比,ARFID中ghrelin的空腹水平没有差异。在ARFID中,在餐后的第一个小时,ghrelin水平比HC下降得更缓慢(p=0.005),但在用餐后60到120分钟之间继续下降,而HC趋于稳定(p=0.005)。禁食和PYY轨迹在各组之间没有差异。调整BMI百分位数(M(SD)ARFID=37(35);M(SD)HC=53(26);p=.006)或测试进餐期间消耗的卡路里(M(SD)ARFID=294(118);M(SD)HC=384(48);p<.001)后,结果没有变化。这些数据突出了在使用ARFID的年轻人中进行测试餐后ghrelin的独特轨迹。未来的研究应该检查生长素释放肽功能障碍作为ARFID的病因或维持因素。
    Disruptions in appetite-regulating hormones may contribute to the development and/or maintenance of avoidant/restrictive food intake disorder (ARFID). No study has previously assessed fasting levels of orexigenic ghrelin or anorexigenic peptide YY (PYY), nor their trajectory in response to food intake among youth with ARFID across the weight spectrum. We measured fasting and postprandial (30, 60, 120 minutes post-meal) levels of ghrelin and PYY among 127 males and females with full and subthreshold ARFID (n = 95) and healthy controls (HC; n = 32). We used latent growth curve analyses to examine differences in the trajectories of ghrelin and PYY between ARFID and HC. Fasting levels of ghrelin did not differ in ARFID compared to HC. Among ARFID, ghrelin levels declined more gradually than among HC in the first hour post meal (p =.005), but continued to decline between 60 and 120 minutes post meal, whereas HC plateaued (p =.005). Fasting and PYY trajectory did not differ by group. Findings did not change after adjusting for BMI percentile (M(SD)ARFID = 37(35); M(SD)HC = 53(26); p =.006) or calories consumed during the test meal (M(SD)ARFID = 294(118); M(SD)HC = 384 (48); p <.001). These data highlight a distinct trajectory of ghrelin following a test meal in youth with ARFID. Future research should examine ghrelin dysfunction as an etiological or maintenance factor of ARFID.
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  • 文章类型: Journal Article
    避免性限制性食物摄入障碍(ARFID)是一种饮食障碍,其特征在于持续的营养和/或能量摄入不足。ARFID,之前被称为“选择性进食障碍”,最近在DSM-5中引入,作为先前诊断的替代和扩展。患有ARFID的个体可能会由于基于食物的感官特征或与饮食的任何不利后果相关的避免而限制食物种类和摄入量,而不打算减肥和关注身体形象。对回避和限制性饮食的有限理解对有效治疗和管理提出了挑战,直接影响儿童和青少年的生长发育。ARFID神经生物学概念尚未明确定义为营养学家的临床实践,从而阻碍筛查并阻碍治疗建议的发展。这篇叙述性综述为查阅病理生理学提供了有用的实用信息,神经生物学,临床特征,为寻求提高对这种疾病的临床知识和管理的医疗保健专业人员进行评估和治疗。
    避免限制性食物摄入障碍(ARFID)是一种饮食障碍,其特征在于持续的营养和/或能量摄入不足。使用ARFID的个人表现出有限的食物摄入量和品种,通常由于缺乏饮食,没有减肥的主要目标。对回避和限制性饮食的有限理解在有效治疗和管理方面提出了挑战,直接影响儿童和青少年的生长发育,以及他们的营养和社会心理健康。ARFID是一个相对较新的诊断分类,代表一个新兴的研究领域。诊断标准的确定和对这一领域新知识的追求最近才开始。因此,评估工具和治疗策略仍在开发和验证过程中。这篇叙事综述使用三维模型探索了ARFID的神经生物学观点,检查其病因和危险因素,评估的临床筛查和评估工具,讨论了常见的临床并发症,并提供不同类型的营养,行为,以及用于ARFID治疗的药物干预措施。
    Avoidant restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent insufficient nutritional and/or energy intake. ARFID, before referred to as \"selective eating disorder\", was introduced recently in the DSM-5 as a replacement for and expansion of the previous diagnosis. Individuals with ARFID may limit food variety and intake due to avoidance based on the sensory characteristics of the food or related to any adverse consequences of eating without the intention of losing weight and concerns of body image. The limited understanding of avoidant and restrictive eating poses challenges to effective treatment and management, impacting directly on the growth and development of children and adolescents. The ARFID neurobiological concept has not yet been clearly defined to clinical practice for nutritionists, thereby hindering screening and impeding the development of treatment recommendations. This narrative review provide useful practical information to consult the pathophysiology, the neurobiology, the clinical features, the assessment and the treatment for healthcare professionals seeking to enhance their clinical knowledge and management of this disorder.
    Avoidant restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent insufficient nutritional and/or energy intake. Individuals with ARFID exhibit limited food intake and variety, often due to a lack in eating, without the primary goal of weight loss. The limited understanding of avoidant and restrictive eating poses challenges in terms of effective treatment and management, which directly impacts the growth and development of children and adolescents, as well as their nutrition and psychosocial well-being. ARFID is a relatively recent diagnostic classification, representing a burgeoning field of study. The identification of diagnostic criteria and the pursuit of new knowledge in this area have only recently begun. Consequently, assessment tools and treatment strategies are still in the process of development and validation. This narrative review explored the neurobiological perspective of ARFID using the three-dimensional model, examined its etiology and risk factors, evaluated clinical screening and evaluation tools, discussed common clinical complications, and presented different types of nutritional, behavioural, and pharmacological interventions used in ARFID treatment.
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  • 文章类型: Journal Article
    患有肠衰竭的婴儿和儿童面临儿科喂养障碍的风险,这挑战了他们的口服喂养发展。本文探讨了这些挑战,并提供了几种实用的策略,可用于多学科护理团队和家庭护理人员,以帮助支持这些儿童的口服喂养的发展,并最终导致他们获得肠道自主权。
    Infants and children with intestinal failure are at risk for pediatric feeding disorders, which challenge their oral feeding development. This article explores these challenges and offers several practical strategies that can be used by multidisciplinary care teams and at-home caregivers to help support the development of oral feeding in these children and eventually lead to their attaining enteral autonomy.
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