public health surveillance

公共卫生监测
  • 文章类型: Journal Article
    背景:怀孕期间经历的粮食不安全(FI)代表了相关的公共卫生问题,因为它会对母婴健康产生负面影响。
    目的:调查COVID-19大流行期间孕妇FI的患病率并确定相关因素。
    方法:在2021年至2022年期间进行了一项横断面研究,根据2016年至2020年在该市唯一的妇产医院发生的平均值(2912例出生)进行了样本计算,得出423名妇女的代表性样本。在分析了病历之后,使用标准化问卷和巴西食品不安全量表对产后妇女进行访谈。使用具有稳健方差的泊松回归来计算患病率比率和95%置信区间来衡量相关性。
    结果:在57.0%的病例中观察到FI,并且与20岁以下的年龄有关(PR=1.52;95%CI1.29;1.79),接受政府援助(PR=1.31;95%CI1.10;1.55),家庭就业损失(PR=1.40;95%CI1.20;1.64),居民人数增加(PR=1.17;95%CI1.00;1.37),和公共机构的产前护理(PR=1.53;95%CI1.04;2.26)。
    结论:FI病例的患病率很高,与社会经济有关,人口统计学,和COVID-19大流行期间的产前护理特征。
    BACKGROUND: Food insecurity (FI) experienced during pregnancy represents a relevant public health problem, as it negatively affects maternal and child health.
    OBJECTIVE: To investigate the prevalence of FI among pregnant women during the COVID-19 pandemic and determine associated factors.
    METHODS: A cross-sectional study was carried out in the period from 2021 to 2022, with a representative sample of 423 women resulting from a sample calculation based on the average (2912 births) that occurred in the years 2016 to 2020 in the only maternity hospital in the municipality. After analyzing the medical records, interviews were carried out with the postpartum women using a standardized questionnaire and the Brazilian Food Insecurity Scale. Poisson regression with robust variance was used to calculate prevalence ratios and 95% confidence intervals to measure associations.
    RESULTS: FI was observed in 57.0% of cases and was associated with age under 20 years (PR = 1.52; 95% CI 1.29; 1.79), receipt of government assistance (PR = 1.31; 95% CI 1.10; 1.55), loss of family employment (PR = 1.40; 95% CI 1.20; 1.64), greater number of residents (PR = 1.17; 95% CI 1.00; 1.37), and prenatal care in a public institution (PR = 1.53; 95% CI 1.04; 2.26).
    CONCLUSIONS: There was a high prevalence of FI cases, associated with socioeconomic, demographic, and prenatal care characteristics during the COVID-19 pandemic.
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  • 文章类型: Journal Article
    背景:成像可能无意中揭示与其表现目的无关的病理,称为偶然发现(IF)。这项研究旨在评估患病率,临床意义,创伤患者的胸部和腹骨盆计算机断层扫描(CT)扫描中的IFs文件。
    方法:这项观察性研究于2019年3月至2022年4月在两个城市一级创伤中心进行。探讨了在急诊科(ED)接受胸部和/或腹骨盆CT扫描的创伤患者的官方放射学报告,并提取了IF。研究了IFs存在的预测因素及其记录。
    结果:在656个胸部和658个腹骨盆CT扫描中,167(25.37%)和212(32.31%)扫描至少包含一个IF,分别。IFs患者的年龄往往较高,胸部均为女性(年龄:48[IQR:35-62]vs.34[IQR:25-42.5];女性:31.14%vs14.66%,两者的p<0.001)和腹骨盆CT扫描(年龄:41[IQR:30-57.5]vs33[IQR:25-43],女性:26.42%vs.13.96%,两者的p<0.001)。至于重要IF的文件,112例胸部IFs中仅有49例(43.8%)和176例腹骨盆IFs中的55例(31.3%)被记录.调查与临床重要IFs记录相关的因素,住院时间较短(1.5(IQR:0-4)与3(IQR:2-8),p=0.003),并由急诊医师出院(文件率:13.2%对42.6%,p<0.001)与仅在腹骨盆扫描中的IFs记录较差相关。
    结论:ED创伤患者的CT成像通常会发现偶然发现,尤其是老年患者。这些发现中有超过50%具有临床意义,然而,他们经常被忽视,没有记录。医生需要更加警惕地识别和记录这些偶然发现,并告知患者需要进一步评估。
    BACKGROUND: Imaging may inadvertently reveal pathologies unrelated to their performing purpose, known as incidental findings (IF). This study aimed to assess the prevalence, clinical significance, and documentation of IFs in chest and abdominopelvic computed tomography (CT) scans of trauma patients.
    METHODS: This observational study was conducted at two urban level-1 trauma centers from March 2019 through April 2022. Official radiology reports of trauma patients who underwent chest and/or abdominopelvic CT scans at the emergency department (ED) were explored, and IF were extracted. Predictive factors of the presence of IFs and their documenting were investigated.
    RESULTS: Out of 656 chest and 658 abdominopelvic CT scans, 167 (25.37%) and 212 (32.31%) scans harbored at least one IF, respectively. Patients with IFs tended to be of higher age and female in both chest (age: 48 [IQR: 35-62] vs. 34 [IQR: 25-42.5]; female: 31.14% vs 14.66%, p < 0.001 for both) and abdominopelvic CT scans (age: 41 [IQR: 30-57.5] vs 33 [IQR: 25-43], female: 26.42% vs. 13.96%, p < 0.001 for both). As for documentation of significant IFs, only 49 of 112 chest IFs (43.8%) and 55 of 176 abdominopelvic IFs (31.3%) were documented. Investigating factors associated with documentation of clinically significant IFs, shorter length of hospital stay (1.5 (IQR: 0-4) vs. 3 (IQR: 2-8), p = 0.003), and discharging by ED physicians (documentation rate: 13.2% vs 42.6%, p < 0.001) were associated with poorer documentation of IFs only in abdominopelvic scans.
    CONCLUSIONS: CT imaging in ED trauma patients often reveals incidental findings, especially in older patients. Over 50% of these findings are clinically significant, yet they are frequently ignored and not documented. Physicians need to be more vigilant in recognizing and documenting these incidental findings and informing patients of the need for further evaluation.
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  • 文章类型: Journal Article
    目的:疾病监测是公共卫生的重要组成部分,也是国家公共卫生研究所(NPHIs)的核心职能,包括更好地准备和应对传染病爆发。加强NPHI努力建立和维持有效的监测系统是确保未来疫情防范和应对的机会;然而,关于如何增加和优先考虑能力建设工作的指导是有限的。本研究旨在研究国家一级疾病监测能力建设和培训的方法,并了解NPHI的潜在作用。
    方法:定性研究。
    方法:这是一项定性研究,基于2022年6月至11月间进行的文献综述和访谈。在五个国家进行了57次深入访谈:科特迪瓦,厄瓜多尔,马达加斯加,纳米比亚,和沙特阿拉伯王国。与会者包括来自政府的一系列专业人士,NPHIs,学术机构和私营部门。对访谈进行了主题分析。
    结果:选定国家的疾病监测能力各不相同,以及他们的监控系统和决策结构。研究确定了国家一级共同的优先行动领域,确定共同的挑战和机遇:1)能力建设,这里特别需要在国家一级制定培训议程,以确保可持续性并指导捐助者资助的培训计划;2)数据工具和技术-帮助决策者选择最佳软件工具来满足国家/地区确定的需求;3)数据共享-需要明确的数据共享标准和规范,以实现国家到国际的数据共享;4)基因组测序-需要国家基因组监测策略和报告指南。
    结论:应对挑战和利用机遇加强国家层面的疾病监测是在这一领域建设能力和帮助预防全球未来流行病和大流行的重要一步。这项研究的结果有助于决策者确定能力建设的优先领域,并了解NPHI的潜在作用和意义。
    OBJECTIVE: Disease surveillance is an essential component of public health and a core function of National Public Health Institutes (NPHIs), including to better prepare and respond to infectious diseases outbreaks. Strengthening NPHIs in their efforts to establish and maintain efficient surveillance systems is an opportunity to ensure future outbreak preparedness and response; yet, guidance on how to increase and prioritise capacity building efforts is limited. This study sought to investigate approaches to capacity building and training for disease surveillance at national level and understand the potential role of NPHIs.
    METHODS: Qualitative study.
    METHODS: This is a qualitative study, based on a literature review and interviews undertaken between June and November 2022. Fifty seven in-depth interviews were conducted in five countries: Côte d\'Ivoire, Ecuador, Madagascar, Namibia, and the Kingdom of Saudi Arabia. Participants included a range of professionals from government, NPHIs, academic institutions and the private sector. Interviews were thematically analysed.
    RESULTS: Selected countries varied in terms of their disease surveillance capacities, as well as in the structure of their surveillance systems and decision-making. Research identified shared priority areas for action at national level, identifying common challenges and opportunities: 1) capacity building, here specifically the need for a training agenda at national level to ensure sustainability and guide donor funded training offers; 2) data tools and technology-to help decision-makers select the best software tool to address countries\' identified need; 3) data sharing-the need for clear data sharing standards and norms for national to international data sharing; and 4) genomic sequencing-the need for national genomic surveillance strategies and reporting guidelines.
    CONCLUSIONS: Addressing challenges and using opportunities to strengthen disease surveillance at national level is an important step to build capacity in this area and to help prevent future epidemic and pandemics globally. The findings of this study help decision-makers to identify priority areas for capacity building and understand the potential role and significance of NPHIs.
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  • 文章类型: Journal Article
    背景:卫生机构呼吁研究评估电子烟(EC)在支持产前戒烟中的使用。这项研究旨在描述(a)在怀孕期间开始使用EC的吸烟者的特征,(b)吸烟者减少或消除产前和产后可燃香烟(CC)使用的频率,和(c)在怀孕期间开始ECs的吸烟者中新生儿健康并发症的风险。
    方法:孕妇在孕前使用CCs,他参加了美国的一项监视研究,根据他们报告的怀孕后期吸烟行为被归类为CC专属用户,EC发起者,或戒烟者。EC发起者进一步细分为双重用户(同时使用EC和CC)或EC替代品(仅使用EC)。
    结果:在29,505名怀孕的吸烟者中,1.5%的人报告在过去3个月内使用ECs。其中,29.7%成为EC独占用户。EC发起人不成比例地是非西班牙裔白人。相对于戒烟者,欧共体发起人的收入较低,不太可能结婚,有意向怀孕,接受孕早期产前护理,并参与联邦援助计划。与CC独占用户相比,EC启动器整体,特别是双重用户,相对于孕前水平,更有可能减少产前和产后CC的使用。EC发起者新生儿健康并发症的风险在戒烟者和CC独占用户之间下降,尽管差异没有统计学意义。
    结论:尽管EC发起者比CC独占用户减少了更多的CC使用量,只有29.7%报告完全停止CC,与CC专属使用者相比,新生儿健康并发症减少的证据不足.目前,ECs不应被视为可行的妊娠期戒烟策略。
    结论:卫生机构已经确定了评估使用电子烟支持产前戒烟的研究的关键需求。使用美国妊娠风险评估监测系统监测研究数据,我们提供了现实世界的证据,即在怀孕的可燃香烟吸烟者中,很少使用产前电子烟作为戒烟工具。大多数在怀孕的最后三个月使用电子烟的人也使用可燃香烟。
    BACKGROUND: Health agencies have called for research evaluating e-cigarette (EC) use in supporting prenatal smoking cessation. This study aimed to describe (a) characteristics of smokers who begin using ECs during pregnancy, (b) how frequently smokers reduce or eliminate pre- and post-natal combustible cigarette (CC) use, and (c) risk for neonatal health complications among smokers who initiate ECs during pregnancy.
    METHODS: Pregnant women using CCs exclusively pre-pregnancy, who participated in a U.S. surveillance study, were classified by their reported late-pregnancy smoking behavior as CC-exclusive users, EC initiators, or quitters. EC initiators were further subclassified as dual users (used both ECs and CCs) or EC replacers (used ECs exclusively).
    RESULTS: Of 29,505 pregnant smokers, 1.5% reported using ECs during the last 3 pregnancy months. Among them, 29.7% became EC-exclusive users. EC initiators were disproportionately non-Hispanic White. Relative to quitters, EC initiators had lower income, were less likely to be married, have intended pregnancies, receive first-trimester prenatal care, and participate in a federal assistance program. Compared to CC-exclusive users, EC initiators overall, and dual users specifically, were more likely to reduce pre- and post-natal CC usage relative to pre-pregnancy levels. EC initiators\' risk for neonatal health complications fell between quitters and CC-exclusive users, though differences were not statistically significant.
    CONCLUSIONS: Although EC initiators reduced CC use more than CC-exclusive users, only 29.7% reported complete CC cessation, and there was insufficient evidence of reduction in neonatal health complications relative to CC-exclusive users. Currently, ECs should not be considered a viable gestational smoking cessation strategy.
    CONCLUSIONS: Health agencies have identified a critical need for research evaluating the use of e-cigarettes in supporting prenatal smoking cessation. Using the US Pregnancy Risk Assessment Monitoring System surveillance study data, we provide real-world evidence that prenatal e-cigarette initiation as a smoking cessation tool is used infrequently among pregnant combustible cigarettes smokers. Most using e-cigarettes in the last three months of pregnancy also used combustible cigarettes.
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  • 文章类型: Journal Article
    阿富汗的持续不稳定,随着持续的疾病爆发和COVID-19大流行的影响,严重影响了这个国家。在COVID-19大流行期间,该国的检测和反应能力面临挑战。从初级到三级的所有医疗机构都进行了病例识别,但忽略了社区一级的病例,导致社区未被发现和不受控制的传播。这强调了基于事件的监视(EBS)可能促进的早期检测的错失机会。因此,阿富汗计划加强国家公共卫生监测系统的EBS部分,以提高快速发现和应对传染病暴发的能力,包括COVID-19和其他新兴疾病。采取这一努力是为了迅速减轻此类疫情的影响。我们对阿富汗的公共卫生监测系统进行了景观评估,以确定增强EBS的最佳方法,然后我们制定了实施工作计划。工作计划包括以下步骤:建立EBS多部门协调和工作组,识别EBS信息源,优先考虑重要的公共卫生事件,定义信号,建立报告机制,并制定标准操作程序和培训指南。EBS目前正在阿富汗的七个省进行试点。从试点阶段吸取的经验教训将支持其在全国的全面扩展。
    The sustained instability in Afghanistan, along with ongoing disease outbreaks and the impact of the COVID-19 pandemic, has significantly affected the country.During the COVID-19 pandemic, the country\'s detection and response capacities faced challenges. Case identification was done in all health facilities from primary to tertiary levels but neglected cases at the community level, resulting in undetected and uncontrolled transmission from communities. This emphasizes a missed opportunity for early detection that Event-Based Surveillance (EBS) could have facilitated.Therefore, Afghanistan planned to strengthen the EBS component of the national public health surveillance system to enhance the capacity for the rapid detection and response to infectious disease outbreaks, including COVID-19 and other emerging diseases. This effort was undertaken to promptly mitigate the impact of such outbreaks.We conducted a landscape assessment of Afghanistan\'s public health surveillance system to identify the best way to enhance EBS, and then we crafted an implementation work plan. The work plan included the following steps: establishing an EBS multisectoral coordination and working group, identifying EBS information sources, prioritizing public health events of importance, defining signals, establishing reporting mechanisms, and developing standard operating procedures and training guides.EBS is currently being piloted in seven provinces in Afghanistan. The lessons learned from the pilot phase will support its overall expansion throughout the country.
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  • 文章类型: Journal Article
    背景:在注射毒品(PWID)人群中消除丙型肝炎的全球发病率目标是<2/100。在挪威,丙型肝炎的流行集中在PWID。移民是慢性感染的第二重要风险群体。我们模拟了活跃PWID中丙型肝炎的发病率,以及慢性感染在活跃的PWID中的患病率,前PWID和挪威的移民,直到2022年。
    方法:我们建立了一个随机隔室模型,使用来自国家数据源的数据,文学,和专家意见。我们报告了95%可信区间(CrI)的中值。
    结果:该模型估计2022年活跃PWID中有30个(95%Crl:13-52)新感染,即0.37/100(95%Crl:0.17-0.65),从2000年的726(95%Crl:506-1067)的峰值下降。在所有团体中,该模型估计了2022年3,202名(95%Crl:1,273-6,601)慢性感染者。敏感性分析结果稳健。
    结论:挪威提供了在集中流行的环境中消除丙型肝炎的可行性的示例,高覆盖率的减害服务和无治疗限制。需要继续保持势头,以进一步减少挪威丙型肝炎的传播和负担。
    BACKGROUND: The global incidence target for the elimination of hepatitis C among people who inject drugs (PWID) is <2/100. In Norway, the hepatitis C epidemic is concentrated in PWID. Immigrants are the second most important risk group for chronic infection. We modelled the incidence of hepatitis C among active PWID, and the prevalence of chronic infection among active PWID, ex-PWID and immigrants in Norway until 2022.
    METHODS: We built a stochastic compartmental model, which was informed using data from national data sources, literature, and expert opinion. We report median values with 95% credible intervals (CrI).
    RESULTS: The model estimated 30 (95% Crl: 13-52) new infections among active PWID in 2022, or 0.37/100 (95% Crl: 0.17-0.65), down from a peak of 726 (95% Crl: 506-1,067) in 2000. Across all groups, the model estimated 3,202 (95% Crl: 1,273-6,601) chronically infected persons in 2022. Results were robust in sensitivity analyses.
    CONCLUSIONS: Norway provides an example of the feasibility of hepatitis C elimination in a setting with a concentrated epidemic, high coverage of harm reduction services and no treatment restrictions. Continued momentum is needed to further reduce the transmission and burden of hepatitis C in Norway.
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  • 文章类型: Journal Article
    尽管存在与数据质量相关的挑战,代表性,以及人工智能驱动工具的准确性,商业上可用的社交收听平台具有许多需要用于在线生态系统中人类乳头瘤病毒疫苗接种错误信息的数字公共卫生监测的属性。
    Despite challenges related to the data quality, representativeness, and accuracy of artificial intelligence-driven tools, commercially available social listening platforms have many of the attributes needed to be used for digital public health surveillance of human papillomavirus vaccination misinformation in the online ecosystem.
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  • 文章类型: Review
    疾病的传播依赖于多种因素,包括事件的特征,比如拥挤和共享住宿,参与者长时间接触和密切接触传染性个体的潜力,活动的类型,以及参与者的特点,例如他们的年龄和对传染因子的免疫力[1-3]。有效控制传染病的爆发需要在高风险环境中进行快速诊断和干预。因此,综合征和基于事件的监测可用于增强监测系统的响应能力[1]。在公共卫生方面,监视正在收集,分析,并跨时间解释数据,为决策和援助政策执行提供信息[1]。在这篇综述文章中,我们旨在概述这些原则,类型,uses,优势,以及监测系统的局限性,并强调早期预警系统对疾病监测收到的信息的重要性。该研究使用多个数据库进行了全面的文献检索,选择,并审查了涵盖不同类型监视系统的78篇文章,他们的应用,以及它们对控制传染病的影响。本文还介绍了朝圣聚会的案例研究,突出了发展,评估,以及预警系统对疾病监测收到的信息的反应的影响。研究得出的结论是,持续的疾病监测应伴随着精心设计的早期预警和反应系统,应不断努力评估和验证这些系统,以最大程度地减少报告延迟的风险并降低爆发的风险。
    Disease transmission is dependent on a variety of factors, including the characteristics of an event, such as crowding and shared accommodations, the potential of participants having prolonged exposure and close contact with infectious individuals, the type of activities, and the characteristics of the participants, such as their age and immunity to infectious agents [1-3]. Effective control of outbreaks of infectious diseases requires rapid diagnosis and intervention in high-risk settings. As a result, syndromic and event-based surveillance may be used to enhance the responsiveness of the surveillance system [1]. In public health, surveillance is collecting, analyzing, and interpreting data across time to inform decision-making and aid policy implementation [1]. In this review article we aimed to provide an overview of the principles, types, uses, advantages, and limitations of surveillance systems and to highlight the importance of early warning systems in response to the information received by disease surveillance. The study conducted a comprehensive literature search using several databases, selecting, and reviewing 78 articles that covered different types of surveillance systems, their applications, and their impact on controlling infectious diseases. The article also presents a case study from the Hajj gathering, which highlighted the development, evaluation, and impact of early warning systems on response to the information received by disease surveillance. The study concludes that ongoing disease surveillance should be accompanied by well-designed early warning and response systems, and continuous efforts should be invested in evaluating and validating these systems to minimize the risk of reporting delays and reducing the risk of outbreaks.
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  • 文章类型: Journal Article
    背景:系统集合,分析,健康监测系统对健康数据的解释提供了对公共卫生的及时和全面的监测,确定健康优先事项,and,因此,迅速和及时的反应,以减少自然灾害期间的损失。由于军队在事故现场作为第一反应者出现,本研究旨在确定自然灾害期间军事卫生保健系统的组成部分。
    方法:通过传统的内容分析方法分析通过半结构化访谈收集的定性数据,以确定自然灾害中军事卫生保健系统的组成部分。参与者由13名专家组成,他们在2022年1月至2022年6月的自然灾害期间在军队和平民医疗保健系统中提供医疗服务方面经验丰富。
    结果:确定的成分分为四个主要类别,即,先决条件组件(全面医疗保健,定义的位置,并提供信息),驱动组件(系统效率,有效沟通),业务组成部分(或有业绩,有效响应),和促销组件(有目的的支持,灾前准备)。
    结论:结论:军事健康监测系统是国家卫生系统的合作服务,在该系统中,数据对于在灾害期间制定健康和治疗措施的决策至关重要。本研究通过确定设计中的重要组成部分的四个类别,实施,和军事健康监测系统的发展-全面了解灾害中适当和基于证据的军事监测系统。
    BACKGROUND: The systematic collection, analysis, and interpretation of health data by health surveillance systems provide timely and comprehensive surveillance of public health, identification health priorities, and, consequently, a quick and timely response to reduce damage during natural disasters. Since military forces appear as first responders at the scene of accidents, the present study aimed to identify the components of the military health care system during natural disasters.
    METHODS: Qualitative data collected through semi-structured interviews were analyzed via the conventional content analysis approach to identify the components of the military health care system in natural disasters. The participants consisted of 13 experts who were experienced in providing health services in the military and the civilian health care system during natural disasters in January 2022 to June 2022.
    RESULTS: The identified components were classified into four main categories, namely, pre-requisite components (comprehensive health care, defined position, and providing information), driving components (system efficiency, effective communication), operational components (contingent performance, effective response), and promotional components (purposeful support, pre-disaster preparation).
    CONCLUSIONS: In conclusion, the military health surveillance system is a cooperative service for the national health system in which data is essential for making decisions on health and treatment measures during disasters. This study-by identifying four categories of the important components in the design, implementation, and development of the military health surveillance system-provides a comprehensive view of an appropriate and evidence-based military surveillance system in disasters.
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  • 文章类型: Journal Article
    背景:小儿肺栓塞(PE)是一种罕见事件,与高发病率和死亡率相关。对儿童特有的临床表现和实践的认识可以帮助临床医生及时识别和治疗。
    目的:为了描述发病率,危险因素,临床表现,诊断和治疗实践,和小儿PE的短期结果。
    方法:我们通过加拿大儿科监测项目进行了一项为期3年的全国监测研究。从2020年到2022年,每月联系2,800多名儿科专家和子专家,并要求报告18岁以下患者的所有新PE病例。具体病例数据是通过自愿填写详细问卷获得的。
    结果:58例(78%为女性,n=45)报告(每百万儿童2.4例),在15至18岁的青少年中发病率最高(每百万6.6例)。详细信息,适用于31例(53%),在28例(90%)病例中记录了至少1个危险因素;24例(77%)患者出现2种或更多种症状。在25例(81%)病例中,使用计算机断层扫描肺动脉造影进行诊断确认。31例中有24例(77%)开始抗凝治疗;不到5例患者接受了溶栓或手术干预。在接受治疗干预的28名患者中,8例(29%)出现治疗相关并发症。据报道死亡人数少于5人。
    结论:小儿PE是一种罕见事件,女性青少年风险最高。虽然介绍通常是非特定的,临床医生应该保持高度怀疑,特别是在有危险因素的患者中,当其他可能解释症状的诊断被排除时.
    BACKGROUND: Pediatric pulmonary embolism (PE) is a rare event associated with significant morbidity and mortality. Awareness of clinical presentation and practices unique to children may aid clinicians in prompt identification and treatment.
    OBJECTIVE: To describe the incidence, risk factors, clinical presentation, diagnostic and therapeutic practices, and short-term outcomes of pediatric PE.
    METHODS: We conducted a 3-year national surveillance study through the Canadian Pediatric Surveillance Program. Over 2800 pediatric specialists and subspecialists were contacted monthly from 2020 to 2022 and requested to report all new cases of PE in patients up to 18 years of age. Case-specific data were obtained through voluntary completion of a detailed questionnaire.
    RESULTS: Fifty-eight cases (78% female, n = 45) were reported (2.4 cases per million children), with rates highest in adolescents 15 to 18 years (6.6 cases per million). Detailed information, available for 31 (53%) cases, documented at least 1 risk factor in 28 (90%) cases; 24 (77%) patients presented with 2 or more symptoms. Computed tomography pulmonary angiography was used for diagnostic confirmation in 25 (81%) cases. Anticoagulation was initiated in 24 (77%) of 31 cases; fewer than 5 patients underwent thrombolysis or surgical interventions. Of 28 patients who received therapeutic interventions, 8 (29%) experienced treatment-related complications. Fewer than 5 mortalities were reported.
    CONCLUSIONS: Pediatric PE is a rare event, with female adolescents at the highest risk. Although the presentation is often nonspecific, clinicians should maintain a high index of suspicion, particularly in patients with risk factors and when other diagnoses that may explain symptoms have been excluded.
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