目的:将Cantion-N®与日常实践中使用的直接修复材料的性能进行比较(例如,树脂基复合材料/RBC,玻璃离聚物水泥/GIC,生物活性树脂,银汞合金)通过系统综述研究。
方法:审查遵循了PRISMA-NMA的建议,审查方案发表在osf.io/ybde8.搜索是在PubMed/MEDLINE进行的,Scopus,WebofScience,Embase,丁香花,和SciELO数据库,以及在灰色文献(开放灰色,Proquest,和佩里奥迪科斯CAPES)。包括具有体外实验设计的研究,该设计评估了与其他修复材料相比的Cention-N的特征和性能。使用RoBDEMAT工具评估纳入研究的偏倚风险,使用ReviewManager5.4和MetaInsightV3工具进行荟萃分析。
结果:本综述共纳入85项研究,其中79项进行了荟萃分析。分析了直接修复材料的几个特点,包括物理(颜色变化,转换程度,硬度,微泄漏,聚合速率,粗糙度,水溶性,水吸附),机械(与牙本质的粘结强度,抗压强度,径向抗拉强度,弯曲模量,抗弯强度,载荷断裂,磨损),和生物(碱化效应,抗菌活性,钙和氟化物释放)特性。
结论:与红细胞相比,Cention-N具有相似的物理机械性能,而是比GIC更强的行为。尽管Cantion-N具有碱解石性质,GIC仍可能从所有直接修复材料中表现出最大的氟化物释放能力。与其他几种传统使用的材料相比,这篇综述证实了Cantion-N的适当行为,确认其适用于永久修复腐烂或骨折的牙齿。
OBJECTIVE: To compare the performance of Cention-N® with direct restorative materials used at the daily practice (e.g., resin-based composites/RBC, glass ionomer cements/GIC, bioactive resins, silver amalgam) via a systematic
review study.
METHODS: The
review followed the PRISMA-NMA recommendations, and the protocol of the
review was published at osf.io/ybde8. The search was conducted in PubMed/MEDLINE, Scopus, Web of Science, Embase, Lilacs, and SciELO databases, as well as in the grey literature (Open Grey, Proquest, and Periódicos CAPES). Studies with an in vitro experimental design evaluating the characteristics and properties of Cention-N in comparison to other restorative materials were included. The risk of bias of included studies was assessed using the RoBDEMAT tool, and meta-analyses were conducted using
Review Manager 5.4 and MetaInsight V3 tools.
RESULTS: A total of 85 studies were included in the
review, from which 79 were meta-analyzed. Several characteristics of direct restorative materials were analyzed, including physical (color change, degree of conversion, hardness, microleakage, polymerization rate, roughness, water solubility, water sorption), mechanical (bond strength to dentin, compressive strength, diametral tensile strength, flexural modulus, flexural strength, load-to-fracture, wear), and biological (alkalinizing effect, antibacterial activity, calcium and fluoride release) properties.
CONCLUSIONS: Cention-N presented similar physico-mechanical properties compared to RBCs, but a stronger behavior than GICs. Despite the Alkasite nature of Cention-N, GICs may still demonstrate the greatest fluoride releasing ability from all direct restorative materials. This
review confirmed the adequate behavior of Cention-N when compared to several other more traditionally used materials, confirming its applicability for the permanent restoration of decayed or fractured teeth.