背景:与轻微软组织挫伤相关的非创伤性肺脂肪栓塞死亡,手术,癌症化疗,血液病等已有报道。患者通常表现为非典型表现和快速恶化,使诊断和治疗变得困难。然而,目前尚无针灸治疗后肺脂肪栓塞死亡病例。这个案例强调了针灸疗法引起的应激,轻微的软组织损伤,在肺脂肪栓塞中起重要作用。此外,这表明在这种情况下,肺脂肪栓塞作为针灸疗法的并发症,需要认真对待,尸检应用于确定脂肪栓塞的来源。
方法:患者为72岁女性,银针治疗后出现头晕和疲劳。尽管进行了治疗和复苏,但她的血压显着下降,并在2小时后死亡。进行了全身尸检和组织病理学检查(H&E和苏丹Ⅲ染色)。在下背部皮肤中观察到超过30个针孔。在皮下脂肪组织的针孔周围可见局灶性出血。微观上,在间质肺动脉和肺泡壁毛细血管中观察到许多脂肪栓塞,除了心脏的血管,肝脏,脾脏和甲状腺。肺部显示充血和水肿。死亡原因被确定为肺脂肪栓塞。
结论:本文建议高度警惕银针针灸疗法后肺脂肪栓塞的危险因素和并发症。在尸检中,应该注意的是,应该检查外周动脉系统和从非损伤部位引流的静脉系统是否有脂肪栓塞的形成,这可以帮助区分创伤后和非创伤肺脂肪栓塞。
BACKGROUND: Death from nontraumatic pulmonary fat embolism associated with minor soft tissue contusion, surgery, cancer chemotherapy, hematologic disorders and so on has been reported. Patients often present with atypical manifestations and rapid deterioration, making diagnosis and treatment difficult. However, there are no reported cases of death from pulmonary fat embolism after acupuncture therapy. This
case emphasizes that the stress induced by acupuncture therapy, a mild soft tissue injury, plays an important role in pulmonary fat embolism. In addition, it suggests that in such cases, pulmonary fat embolism as a complication of acupuncture therapy needs to be taken seriously, and autopsy should be used to identify the source of fat emboli.
METHODS: The patient was 72 years old female and experienced dizziness and fatigue after
silver-needle acupuncture therapy. She experienced a significant drop in blood pressure and died 2 h later despite treatment and resuscitation. A systemic autopsy and histopathology examination (H&E and Sudan Ⅲ staining) were performed. More than 30 pinholes were observed in the lower back skin. Focal hemorrhages were seen surrounding the pinholes in the subcutaneous fatty tissue. Microscopically, numerous fat emboli were observed in the interstitial pulmonary arteries and alveolar wall capillaries, in addition to the vessels of the heart, liver, spleen and thyroid gland. The lungs showed congestion and edema. The cause of death was identified as pulmonary fat embolism.
CONCLUSIONS: This article suggests that high vigilance for risk factors and the complication of pulmonary fat embolism following
silver-needle acupuncture therapy should be exercised. In postmortem examinations, it should be pay attention that the peripheral arterial system and the venous system draining from non-injured sites should be examined for the formation of fat emboli, which can help distinguish posttraumatic and nontraumatic pulmonary fat embolism.