• 文章类型: Journal Article
    骶尾部藏毛窦(SPS)是一种常见病,其特征是在骶尾部区域形成窦道或腔,通常含有头发和碎片。由于其慢性和复发性,手术管理在其治疗中起着至关重要的作用。这篇全面的综述探讨了SPS手术管理的进步和创新。回顾首先是对历史观点的概述,解剖学,和疾病的病理生理学,接下来是对当前手术技术的讨论,包括常规切除,襟翼程序,和微创方法。最近的进步,比如激光治疗,放射引导技术,和机器人辅助手术,也检查了。总结了结果研究的关键发现,包括术后疼痛管理,复发率,患者满意度。对临床实践的影响进行了讨论,强调保持最新外科技术和采用个性化治疗方法的重要性。提供了对未来研究的建议,强调需要比较不同的手术技术进行前瞻性研究,以及针对复发风险的微创方法和预测模型的研究。研究人员之间的合作,临床医生,行业合作伙伴对于推动SPS患者的创新和改善预后至关重要。
    Sacrococcygeal pilonidal sinus (SPS) is a common condition characterized by the formation of a sinus tract or cavity in the sacrococcygeal region, often containing hair and debris. Surgical management plays a crucial role in its treatment due to its chronic and recurrent nature. This comprehensive review explores the advancements and innovations in the surgical management of SPS. The review begins with an overview of the historical perspective, anatomy, and pathophysiology of the condition, followed by a discussion of current surgical techniques, including conventional excision, flap procedures, and minimally invasive approaches. Recent advancements, such as laser therapy, radiological guidance techniques, and robotic-assisted surgery, are also examined. The key findings from outcomes research are summarized, including postoperative pain management, recurrence rates, and patient satisfaction. The implications for clinical practice are discussed, emphasizing the importance of staying updated on the latest surgical techniques and adopting a personalized approach to treatment. Recommendations for future research are provided, highlighting the need for prospective studies comparing different surgical techniques, as well as research focusing on minimally invasive approaches and predictive models for recurrence risk. Collaboration among researchers, clinicians, and industry partners is essential to drive innovation and improve outcomes for patients with SPS.
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  • 文章类型: Case Reports
    我们报告了一例通过腹外缝合进行初次闭合修复的Morgagni疝。此外,我们回顾了腹腔镜修复的Morgagni疝病例,已知疝气缺损的大小,建立网格利用率的尺寸标准。一名87岁的妇女因右上腹部疼痛和呕吐来到我们医院。她没有腹部手术或外伤史。胸部X线摄影和计算机断层扫描(CT)显示Morgagni疝,胃和横结肠突出进入右胸腔。最初,由于她的年龄,对胃疝进行了内窥镜修复,这是成功的。然而,两天后她复发了,促使我们进行半紧急腹腔镜手术。腹腔镜检查显示有Morgagni缺陷,用网膜,横结肠,胃突出,胃因气腹而缩小。幸运的是,突出的器官可以很容易地重新定位到腹部,没有粘连。疝缺损测量为6x3厘米。我们用腹外缝合进行了初次闭合。未进行囊切除。手术持续98分钟。术后第1天开始口服,患者于术后第3天出院,无并发症。术后1个月胸部X线和CT扫描显示无复发,在9个月的随访检查中,患者仍无症状。根据我们的审查结果,原发性闭合是治疗小疝缺损的有效方法(经验法则:宽度,<4厘米;长度,<7厘米)。
    We report a case of a Morgagni hernia repaired by primary closure with an extra-abdominal suture. Moreover, we reviewed cases of laparoscopically repaired Morgagni hernia, in which the size of the hernia defect was known, to establish a size criterion for mesh utilization. An 87-year-old woman presented to our hospital with right upper abdominal pain and vomiting. She had no history of abdominal surgery or trauma. Chest radiography and computed tomography (CT) revealed a Morgagni hernia, with the stomach and transverse colon herniated into the right chest cavity. Initially, an endoscopic repair was performed for the herniated stomach due to her age, which was successful. However, she had a recurrence 2 days later, prompting us to perform a semi-emergent laparoscopic surgery. Laparoscopic examination revealed a Morgagni defect, with the omentum, transverse colon, and stomach herniated, with the stomach reduced by pneumoperitoneum. Fortunately, the herniated organs could be easily relocated into the abdomen with no adhesions. The hernia defect measured 6 x 3 cm. We performed primary closure with an extra-abdominal suture. No sac resection was performed. The operation lasted 98 min. Oral intake was initiated on postoperative day 1, and the patient was discharged on postoperative day 3 without complications. Chest radiography and CT scans at 1 month postoperatively showed no recurrence, and the patient remained asymptomatic at the 9-month follow-up examination. According to our review findings, primary closure is an efficient method for small hernia defects (rule of thumb: width, <4 cm; length, <7 cm).
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  • 文章类型: Journal Article
    区域麻醉在儿科患者的术后疼痛管理中越来越受欢迎。腰痛阻滞(QLB)被认为是腹部手术中使用的围手术期疼痛管理技术之一。然而,尚未就最佳方法达成共识。
    60名年龄在1至6岁之间的儿科患者,以及美国麻醉师学会的I级和II级患者,计划腹腔镜腹股沟疝,被分配接受后入路(I组)或前入路(II组)QLB。二十四小时吗啡消耗,脸,腿,活动,哭泣,和可操纵性(FLACC)得分,镇痛持续时间,性能时间,记录与阻滞相关的并发症.
    II组显示出吗啡消耗显着降低以及镇痛持续时间更长(P=0.039*,0.020*,分别),两组的阻滞表现时间相同(P=0.080)。术后2、4、6和12小时,与I组相比,II组的FLACC评分显着降低(P=0.001*,0.012*,0.002*,0.028*,分别)。然而,二十四小时后,两组间疼痛评分具有可比性(P=0.626).此外,无阻滞相关并发症.
    在计划进行腹腔镜腹股沟疝修补术的儿科患者中,超声引导下QLB前路手术与术后吗啡消耗显著减少相关,较低的FLACC分数,与后路相比,镇痛持续时间更长。
    UNASSIGNED: Regional anaesthesia has gained popularity in managing post-operative pain in paediatric patients. Quadratus lumborum block (QLB) is recognised as one of the peri-operative pain management techniques used during abdominal surgeries. However, no consensus about the best approach has been reached.
    UNASSIGNED: Sixty paediatric patients with ages ranging from 1 to 6 as well as classification I and II of the American Society of Anesthesiologists, scheduled for laparoscopic inguinal hernia, were allocated to receive either a posterior approach (Group I) or an anterior approach (Group II) QLB. Twenty four-hour morphine consumption, the face, legs, activity, cry, and consolability (FLACC) score, duration of analgesia, performance time, and block-related complications were recorded.
    UNASSIGNED: Group II showed significantly lower morphine consumption as well as a longer duration of analgesia (P = 0.039*, 0.020*, respectively), with an equivalent period for block performance being reported in the two groups (P = 0.080). At 2, 4, 6, and 12 hours post-operatively, the FLACC scores were substantially diminished in Group II compared to Group I (P = 0.001*, 0.012*, 0.002*, 0.028*, respectively). However, at twenty-four hours, comparable pain scores were observed between both groups (P = 0.626). In addition, there were no block-related complications.
    UNASSIGNED: In paediatric patients scheduled for laparoscopic inguinal hernia repair, the ultra-sound-guided anterior approach of the QLB was associated with significantly reduced post-operative morphine consumption, a lower FLACC score, and a longer analgesia duration when compared to the posterior approach.
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  • 文章类型: Journal Article
    这项研究开发并验证了手术器械运动测量系统,用于在实际腹腔镜手术培训中进行技能评估。由于腹腔镜手术的各种优点,包括微创,该技术已被广泛使用。然而,由于外科医生短缺和工作时间有限,专家外科医生没有足够的时间为初学者提供培训。必须提高技能转移效率,迫切需要开发客观的手术技能评估方法。因此,开发了一种简单的基于运动捕获的手术器械运动测量系统,该系统可以很容易地安装在手术室中,以便在实际手术培训期间进行技能评估。基于附接到器械根部的标记物位置来计算器械的尖端位置和取向。因为这些标记的模式是个体的,该系统可以同时跟踪多个仪器并检测交换。然而,由于手术室中的许多障碍,测量数据包括噪声和异常值。在这项研究中,确定了测量精度降低对特征计算的影响。在湿实验室培训期间进行了准确性验证实验,以证明该系统能够以实际准确性测量手术器械的运动。在尸体上进行了手术训练实验,在36例腹腔镜肾癌根治术中测量了6种手术器械的运动。还开发了异常值去除和平滑方法,并将其应用于去除所获得数据中的噪声和异常值。实验期间进行的问卷调查证实,测量系统没有干扰外科手术。因此,所提出的系统能够在对手术影响最小的情况下进行可靠的测量。该系统将通过评估手术技能的技能转移来促进手术教育。
    This study developed and validated a surgical instrument motion measurement system for skill evaluation during practical laparoscopic surgery training. Owing to the various advantages of laparoscopic surgery including minimal invasiveness, this technique has been widely used. However, expert surgeons have insufficient time for providing training to beginners due to the shortage of surgeons and limited working hours. Skill transfer efficiency has to be improved for which there is an urgent need to develop objective surgical skill evaluation methods. Therefore, a simple motion capture-based surgical instrument motion measurement system that could be easily installed in an operating room for skill assessment during practical surgical training was developed. The tip positions and orientations of the instruments were calculated based on the marker positions attached to the root of the instrument. Because the patterns of these markers are individual, this system can track multiple instruments simultaneously and detect exchanges. However due to the many obstacles in the operating room, the measurement data included noise and outliers. In this study, the effect of this decrease in measurement accuracy on feature calculation was determined. Accuracy verification experiments were conducted during wet-lab training to demonstrate the capability of this system to measure the motion of surgical instruments with practical accuracy. A surgical training experiment on a cadaver was conducted, and the motions of six surgical instruments were measured in 36 cases of laparoscopic radical nephrectomy. Outlier removal and smoothing methods were also developed and applied to remove the noise and outliers in the obtained data. The questionnaire survey conducted during the experiment confirmed that the measurement system did not interfere with the surgical operation. Thus, the proposed system was capable of making reliable measurements with minimal impact on surgery. The system will facilitate surgical education by enabling the evaluation of skill transfer of surgical skills.
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  • 文章类型: Journal Article
    目的:Lu的方法用于电视胸腔镜手术(LVATS),源自UVATS,是一种新颖的VATS手术方法,并对肺癌切除术进行了微创新。这项研究的目的是阐明安全性,可行性,和这种新型手术方法的疗效。
    方法:在3月之间接受了根治性胸腔镜肺叶切除术的非小细胞肺癌(NSCLC)患者的临床资料。2021年3月2022年,回顾性收集,并分析。根据在VATS操作过程中是否应用了Lu\'s方法,患者分为LVATS组和UVATS组。使用倾向评分(PS)匹配方法通过创建两组来减少选择偏差。生成PS后,完成1:1比率和最近邻分数匹配。围手术期变量,包括手术时间,术中失血,淋巴结站解剖,总排水量,排水持续时间,术后住院时间,疼痛评分(VAS,视觉模拟评分)在术后第一天(POD1)和第三天(POD3),术后并发症的发生率,对两组进行比较。对数据进行统计学分析,P<0.05定义为有统计学意义。
    结果:共确认182例患者,其中86例患者接受LVATS和96例UVATS。在这项回顾性研究中,倾向匹配产生了62对。围手术期无死亡病例。LVATS组患者的手术时间较短(88(75,106)VS122(97,144)min,P<0.001),术中出血量少(20(20,30)VS25(20,50)ml,P=0.021),缩短切口长度(2.50(2.50,2.50)VS3.00(3.00,3.50)cm,P<0.001),和更多的排水量(460(310,660)VS345(225,600)毫升,P=0.041)高于UVATS组患者。解剖的淋巴结位置没有显着差异(5(4,5)VS5(4,5),P=0.436),排水持续时间(3(3,4)VS3(3,4)天,P=0.743),术后住院时间(4(4,5)VS4(4,6)天,P=0.608),POD1上的VAS(4(4,4)VS4(4,4),P=0.058)和POD3(3(3,4)VS4(3,4),P=0.219),术后并发症发生率(P=0.521)。
    结论:Lu\的方法是一种安全可行的方法,用于电视胸腔镜下NSCLC的肺叶切除术。这种方法可以缩短手术时间,减少切口长度和术中失血量。
    OBJECTIVE: Lu\'s approach for video-assisted thoracoscopic surgery (LVATS), which derives from UVATS, is a novel surgical approach for VATS and carries out micro-innovation for lung cancer resection. The objective of this study is to elucidate the safety, feasibility, and efficacy of this novel surgical approach.
    METHODS: The clinical data of patients with non-small cell lung cancer (NSCLC) who underwent a curative thoracoscopic lobectomy between Mar. 2021 and Mar. 2022, were retrospectively collected, and analyzed. According to whether applied Lu\'s approach during the VATS operation, patients were divided into the LVATS group and the UVATS group. The propensity score (PS) matching method was used to reduce selection bias by creating two groups. After generating the PSs, 1:1 ratio and nearest-neighbor score matching was completed. Perioperative variables, including the operation time, intraoperative blood loss, lymph node stations dissected, total drainage volume, drainage duration, postoperative hospital stay, pain score (VAS, Visual Analogue Scale) on the postoperative first day (POD1) and third day (POD3), and incidence of postoperative complications, were compared between the two groups. The data were analyzed statistically with P<0.05 defined as statistically significant.
    RESULTS: A total of 182 patients were identified, among whom 86 patients underwent LVATS and 96 UVATS. Propensity matching produced 62 pairs in this retrospective study. There were no deaths during perioperative period. Patients in the LVATS group experienced a shorter operation time (88 (75, 106) VS 122 (97, 144)min, P <0.001), less intraoperative blood loss(20 (20, 30) VS 25 (20, 50)ml, P = 0.021), shorten incision length (2.50 (2.50, 2.50) VS 3.00 (3.00, 3.50)cm, P <0.001), and more drainage volume (460 (310, 660) VS 345 (225, 600)ml, P = 0.041) than patients in the UVATS group. There was not significant difference in the lymph node stations dissected(5 (4, 5) VS 5 (4, 5), P = 0.436), drainage duration (3 (3, 4) VS 3 (3, 4)days, P = 0.743), length of postoperative hospital stay (4 (4, 5) VS 4 (4, 6)days, P = 0.608), VAS on the POD1(4 (4, 4) VS 4 (4, 4), P = 0.058)and POD3 (3 (3, 4) VS 4 (3, 4), P = 0.219), and incidence of postoperative complications (P = 0.521) between the two groups.
    CONCLUSIONS: Lu\'s approach is a safe and feasible approach for video-assisted thoracoscopic surgery for the lobectomy of NSCLC. This approach can shorten surgical time, reduce incision length and intraoperative blood loss.
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  • 文章类型: Multicenter Study
    手术技术对于确保安全的微创肾上腺切除术至关重要。由于肾上腺手术的相对罕见,在手术训练中确保足够的暴露是具有挑战性的。手术视频分析支持自动评估,专家评估,并可能成为自动化的目标。开发的本体论得到了欧洲专家共识的验证,适用于所有参与中心遇到的外科技术。在双中心录音中进行了示范演示。肾上腺切除术视频分析的标准化可以促进手术训练并实现用于自动安全警报的机器学习训练。
    Surgical technique is essential to ensure safe minimally invasive adrenalectomy. Due to the relative rarity of adrenal surgery, it is challenging to ensure adequate exposure in surgical training. Surgical video analysis supports auto-evaluation, expert assessment and could be a target for automatization. The developed ontology was validated by a European expert consensus and is applicable across the surgical techniques encountered in all participating centres, with an exemplary demonstration in bi-centric recordings. Standardization of adrenalectomy video analysis may foster surgical training and enable machine learning training for automated safety alerts.
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  • 文章类型: Case Reports
    宫颈阴道细胞学中的腺瘤体是与恶性肿瘤相关的罕见发现。一名62岁的妇女被转诊到我们的细胞学中心,患有核异型性和可疑恶性肿瘤的砂膜体。进行了完整的妇科检查,包括阴道镜检查和超声检查,无明显变化。进行宫腔镜检查以检测子宫内膜或宫颈内恶性肿瘤,子宫内膜活检显示子宫内膜和萎缩性子宫内膜。宫颈和宫颈活检均为恶性肿瘤阴性。重复宫颈阴道细胞学和人乳头瘤病毒(HPV)检测。结果提示腺癌,HPV阴性。腹腔镜子宫切除术和双侧附件卵巢切除术是由于两个宫颈阴道细胞学检查,怀疑恶性肿瘤。在子宫表面诊断出低度腹膜浆液性癌,卵巢和腹膜。进行第二次腹腔镜检查以排除其他骨盆或腹部病变,在骨盆的腹膜中发现了疾病,腹部和网膜。需要使用六个周期的卡铂和紫杉醇辅助治疗。宫颈阴道细胞学检查是一种罕见的临床情况,并且必须排除恶性肿瘤。
    Psammoma bodies in cervicovaginal cytology are a rare finding associated with malignant tumours. A 62-year-old woman was referred to our centre for cytology with nuclear atypia and psammomatous bodies suspicious of malignancy. A complete gynaecological examination was performed including colposcopy and ultrasound without significant changes. Hysteroscopy was performed to detect endometrial or endocervical malignancy, endometrial biopsy showed psammoma bodies and atrophic endometrium. Endocervical and cervical biopsies were negative for malignancy. Cervicovaginal cytology and human papillomavirus (HPV) testing were repeated. The result was suggestive of adenocarcinoma and negative for HPV. Laparoscopic hysterectomy with bilateral salpingo-oophorectomy was indicated due to two cervicovaginal cytologies with suspicion of malignancy. Low-grade peritoneal serous carcinoma was diagnosed on the surface of the uterus, ovaries and peritoneum. A second laparoscopy was performed to exclude other pelvic or abdominal lesions, and disease was found in the peritoneum of the pelvis, abdomen and omentum. Adjuvant treatment with six cycles of carboplatin and paclitaxel was indicated. Psammoma bodies in cervicovaginal cytology are a rare clinical situation, and it is mandatory to exclude malignancy.
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  • 文章类型: Journal Article
    背景:气管内插管通常与术后并发症有关,例如喉咙痛不适和声音嘶哑,降低患者满意度,延长住院时间。喉罩(LMA)在减少气管插管相关的气道并发症中起着至关重要的作用。这项荟萃分析是为了确定LMA在电视胸腔镜手术(VATS)中的有效性和安全性。
    方法:PubMed,Embase,科克伦图书馆,从开始到2023年10月5日,搜索Medline和WebofScience数据库以寻找合格的研究。使用Cochrane工具(RoB2)评估RCT的可能性偏差。我们进行了敏感性分析和亚组分析以评估结果的稳健性。
    结果:本荟萃分析纳入了7篇文献。与气管插管相比,术后住院时间差异无统计学意义(SMD=-0.47,95%CI=-0.98-0.03,P=0.06),术中最低SpO2(SMD=0.00,95%CI=-0.49-0.49,P=1.00),低氧血症(RR=1.00,95%CI=0.26-3.89,P=1.00),术中最高PetCO2(SMD=0.51,95%CI=-0.12-1.15,P=0.11),手术野满意度(RR=1.01,95%CI=0.98-1.03,P=0.61),麻醉时间(SMD=-0.10,95%CI=-0.30-0.10,P=0.31),LMA组手术时间(SMD=0.06,95%CI=-0.13~0.24,P=0.55)和失血量(SMD=-0.13,95%CI=-0.33~0.07,P=0.21)。然而,LMA与较低的喉部不适发生率(RR=0.28,95%CI=0.17-0.48,P<0.00001)和术后声音嘶哑发生率(RR=0.36,95%CI=0.16-0.81,P=0.01)相关,气管插管与术后清醒时间延长有关(SMD=-2.19,95%CI=-3.49--0.89,P=0.001)。
    结论:与气管插管相比,LMA可有效降低VATS后咽喉不适和声音嘶哑的发生率,并能加速麻醉的恢复.对于某些特定的胸外科手术,LMA似乎是气管插管的替代方法。LMA在VATS中的疗效和安全性有待进一步探讨。
    BACKGROUND: Endotracheal intubation is often associated with postoperative complications such as sore throat discomfort and hoarseness, reducing patient satisfaction and prolonging hospital stays. Laryngeal mask airway (LMA) plays a critical role in reducing airway complications related to endotracheal intubation. This meta-analysis was performed to determine the efficacy and safety of LMA in video-assisted thoracic surgery (VATS).
    METHODS: The PubMed, Embase, Cochrane Library, Medline and Web of Science databases were searched for eligible studies from inception until October 5, 2023. Cochrane\'s tool (RoB 2) was used to evaluate the possibility biases of RCTs. We performed sensitivity analysis and subgroup analysis to assess the robustness of the results.
    RESULTS: Seven articles were included in this meta-analysis. Compared with endotracheal intubation, there was no significant difference in the postoperative hospital stay (SMD = -0.47, 95% CI = -0.98-0.03, P = 0.06), intraoperative minimum SpO2 (SMD = 0.00, 95% CI = -0.49-0.49, P = 1.00), hypoxemia (RR = 1.00, 95% CI = 0.26-3.89, P = 1.00), intraoperative highest PetCO2 (SMD = 0.51, 95% CI = -0.12-1.15, P = 0.11), surgical field satisfaction (RR = 1.01, 95% CI = 0.98-1.03, P = 0.61), anesthesia time (SMD = -0.10, 95% CI = -0.30-0.10, P = 0.31), operation time (SMD = 0.06, 95% CI = -0.13-0.24, P = 0.55) and blood loss (SMD =- 0.13, 95% CI = -0.33-0.07, P = 0.21) in LMA group. However, LMA was associated with a lower incidence of throat discomfort (RR = 0.28, 95% CI = 0.17-0.48, P < 0.00001) and postoperative hoarseness (RR = 0.36, 95% CI = 0.16-0.81, P = 0.01), endotracheal intubation was found in connection with a longer postoperative awake time (SMD = -2.19, 95% CI = -3.49 - -0.89, P = 0.001).
    CONCLUSIONS: Compared with endotracheal intubation, LMA can effectively reduce the incidence of throat discomfort and hoarseness post-VATS, and can accelerate the recovery from anesthesia. LMA appears to be an alternative to endotracheal intubation for some specific thoracic surgical procedures, and the efficacy and safety of LMA in VATS need to be further explored in the future.
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  • 文章类型: Journal Article
    背景:与腹腔镜手术相比,机器人辅助治疗局部晚期癌症的潜在益处尚未得到前瞻性研究的充分证明。据推测,一个因素是缺乏严格的外科医生标准。这项研究的目的是评估具有严格的外科医生经验标准的局部晚期直肠癌患者的机器人手术结果。
    方法:设定了一项标准,要求外科医生进行超过40例机器人辅助直肠癌手术。在2020年3月至2022年5月之间,直肠癌患者(距肛门边缘12厘米或更小,cT2-T4a,cN0-N3、cM0或cT1-T4a,cN1-N3,cM0)被注册。主要终点是来自病理标本的环状切缘(CRM)阳性率。次要终点是手术结果,病理结果,术后并发症,和长期结果。
    结果:在321名注册患者中,对303进行了分析,不包括18个不合格的。诊断时:I期(n=68),阶段II(n=84)和阶段III(n=151)。56例患者采用新辅助治疗。没有转换为开放手术。直肠切除的中位控制台时间为170分钟,中位失血量为5ml。14例患者CRM阳性(4.6%)。13例患者(4.3%)观察到III-IV级术后并发症。
    结论:当使用严格的外科医生标准时,机器人辅助手术对于局部晚期直肠癌是可行的。
    BACKGROUND: The potential benefits of robotic-assisted compared with laparoscopic surgery for locally advanced cancer have not been sufficiently proven by prospective studies. One factor is speculated to be the lack of strict surgeon criteria. The aim of this study was to assess outcomes for robotic surgery in patients with locally advanced rectal cancer with strict surgeon experience criteria.
    METHODS: A criterion was set requiring surgeons to have performed more than 40 robotically assisted operations for rectal cancer. Between March 2020 and May 2022, patients with rectal cancer (distance from the anal verge of 12 cm or less, cT2-T4a, cN0-N3, cM0, or cT1-T4a, cN1-N3, cM0) were registered. The primary endpoint was the rate positive circumferential resection margin (CRM) from the pathological specimen. Secondary endpoints were surgical outcomes, pathological results, postoperative complications, and longterm outcomes.
    RESULTS: Of the 321 registered patients, 303 were analysed, excluding 18 that were ineligible. At diagnosis: stage I (n = 68), stage II (n = 84) and stage III (n = 151). Neoadjuvant therapy was used in 56 patients. There were no conversions to open surgery. The median console time to rectal resection was 170 min, and the median blood loss was 5 ml. Fourteen patients had a positive CRM (4.6%). Grade III-IV postoperative complications were observed in 13 patients (4.3%).
    CONCLUSIONS: Robotic-assisted surgery is feasible for locally advanced rectal cancer when strict surgeon criteria are used.
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  • 文章类型: Case Reports
    甲氨蝶呤(MTX)相关的淋巴增生性疾病(LPD)是与MTX治疗相关的最突出的晚期并发症之一。尽管与MTX相关的LPD表现出相对较高的结外疾病发病率,膀胱的发病率很低。本研究报告了一例与MTX相关的LPD患者,涉及膀胱肿块。一位75岁的女性患者,已经接受MTX约15年了,因发烧和血尿被转诊到医院。计算机断层扫描显示膀胱壁增厚,肾积水和淋巴结肿大。膀胱肿块的组织病理学发现导致MTX相关LPD的诊断。虽然MTX退出没有任何效果,随后的化疗导致完全缓解.尽管膀胱中与MTX相关的LPD很少见,当在MTX治疗期间观察到血尿时,应考虑与MTX相关的LPD.
    Methotrexate (MTX)-related lymphoproliferative disease (LPD) is one of the most prominent late complications associated with MTX treatment. Although MTX-related LPD exhibits a relatively high incidence of extranodal disease, the incidence of disease in a urinary bladder is very low. The present study reports the case of a patient with MTX-related LPD involving a urinary bladder mass. A 75-year-old female patient, who had been receiving MTX for ~15 years, was referred to the hospital due to fever and hematuria. A computed tomography scan revealed the thickening of the urinary bladder wall, hydronephrosis and lymph node swelling. The histopathological findings of the urinary bladder mass resulted in a diagnosis of MTX-related LPD. Although MTX withdrawal did not have any effect, the subsequent chemotherapy resulted in complete remission. Although MTX-related LPD in the bladder is rare, it is pertinent to consider MTX-related LPD when hematuria is observed during MTX therapy.
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