• 文章类型: Journal Article
    背景:目前,研究比较不同端口达芬奇机器人辅助手术下肺癌解剖切除的短期术后结局。本报告旨在比较三端口和四端口达芬奇机器人辅助胸腔镜手术治疗肺癌根治术的效果。
    方法:回顾性收集2020年1月至2021年10月我院收治的非小细胞肺癌患者171例,并采用达芬奇机器人胸腔镜手术进行肺癌根治术,分为三孔组(n=97)和四孔组(n=74)。一般临床资料,分别比较两组患者围手术期资料和生活质量。
    结果:171例患者均手术成功。与四端口组相比,三端口组在年龄方面具有可比的基线特征,性别,肿瘤位置,肿瘤大小,慢性病史,病理类型,和病理分期。三端口组手术时间也较短,术中失血少,下胸管引流量,术后住院时间较短,但差异无统计学意义(P>0.05)。术后24、48和72h视觉模拟疼痛评分在三端口组降低(p<0.001)。两组患者的住院费用差异无统计学意义(P=0.664)。总淋巴结清扫数(P>0.05)及术后呼吸道并发症(P>0.05)。
    结论:在非小细胞肺癌中,三端口机器人辅助胸腔镜手术是安全有效的,并且取得了比四端口机器人辅助胸腔镜手术更好的效果。
    BACKGROUND: At present, research comparing the short-term postoperative outcomes of anatomical resection in lung cancer under different ports of da Vinci robot-assisted surgery is insufficient. This report aimed to compare the outcomes of three-port and four-port da Vinci robot-assisted thoracoscopic surgery for radical dissection of lung cancer.
    METHODS: 171 consecutive patients who presented to our hospital from January 2020 to October 2021 with non-small cell lung cancer and treated with da Vinci robot-assisted thoracoscopic surgery for radical resection of lung cancer were retrospectively collected and divided into the three-port group (n = 97) and the four-port group (n = 74). The general clinical data, perioperative data and life quality were individually compared between the two groups.
    RESULTS: All the 171 patients successfully underwent surgeries. Compared to the four-port group, the three-port group had comparable baseline characteristics in terms of age, sex, tumor location, tumor size, history of chronic disease, pathological type, and pathological staging. The three-port group also had shorter operation time, less intraoperative blood loss, lower chest tube drainage volume, shorter postoperative hospitalization stay durations, but showed no statistically significant difference (P > 0.05). Postoperative 24, 48 and 72 h visual analogue scale pain scores were lower in the three-port group (p < 0.001). No significant difference was observed between the two groups in the hospitalization costs (P = 0.664), number or stations of total lymph node dissected (p > 0.05) and postoperative respiratory complications (P > 0.05).
    CONCLUSIONS: The three-port robot-assisted thoracoscopic surgery is safe and effective and took better outcomes than the four-port robot-assisted thoracoscopic surgery in non-small cell lung cancer.
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  • 文章类型: Case Reports
    背景:原发性肺脑膜瘤(PPM)是一种非常罕见的起源于肺内脑膜的肿瘤。尽管与中枢神经系统(CNS)相似,PPM由于其不经常发生而提出了独特的诊断挑战和治疗考虑。
    方法:本病例报告描述了一名73岁的男性,他接受了胸部计算机断层扫描(CT)检查,显示右下叶后基底段有肿块,提示约30-40毫米大小的低度恶性肿瘤。单孔电视胸腔镜手术(VATS)通过局部病灶切除(肺楔形切除术)切除肿块。术中冰冻切片病理提示低度恶性上皮性肿瘤,导致最大肺功能保留的决定,考虑到病人的高龄。手术团队选择了局部切除以确保阴性切缘。组织病理学分析证实了上皮样PPM的诊断,甚至在PPM病例中也是一种罕见的亚型(世界卫生组织[WHO]I级)。患者术后9天出院,无并发症发生,术后1个月恢复正常日常活动。PPM的稀有性排除了标准化的治疗方案,以手术切除为主要方法。然而,由于证据有限,辅助治疗的疗效仍不确定.
    结论:本病例报告有助于更好地理解PPM,并强调对这种罕见实体进行全面诊断评估和个体化治疗计划的重要性。
    BACKGROUND: Primary pulmonary meningioma (PPM) is an exceedingly rare neoplasm originating in the meninges within the lung. Despite sharing similarities with its central nervous system (CNS) counterparts, PPM presents unique diagnostic challenges and therapeutic considerations owing to its infrequent occurrence.
    METHODS: This case report describes a 73-year-old male who underwent chest computed tomography (CT), which revealed a mass in the posterior basal segment of the right lower lobe, suggestive of a low-grade malignant tumor approximately 30-40 mm in size. Single-port video-assisted thoracoscopic surgery (VATS) was performed to resect the mass via localized lesion excision (lung wedge resection). Intraoperative frozen section pathology indicated a low-grade malignant epithelial tumor, leading to a decision for maximal lung function preservation, considering the patient\'s advanced age. The surgical team opted for a localized excision to ensure negative margins. Histopathological analysis confirmed the diagnosis of epithelioid PPM, a rare subtype even among PPM cases (World Health Organization [WHO] Grade I). The patient was discharged 9 days after surgery without complications and resumed normal daily activities 1 month postoperatively. The rarity of PPM precludes a standardized treatment protocol, with surgical resection as the primary approach. However, the efficacy of adjunctive therapies remains uncertain due to limited evidence.
    CONCLUSIONS: This case report contributes to a better understanding of PPM and emphasizes the importance of a comprehensive diagnostic evaluation and individualized treatment planning for this rare entity.
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  • 文章类型: Journal Article
    目的:急性阑尾炎是小儿外科急腹症最常见的原因之一。目的观察综合快速康复护理在腹腔镜阑尾切除术(LA)患儿围手术期的应用效果。
    方法:回顾性选择2022年1月至2023年1月在我院行LA的200例阑尾炎患儿作为研究对象。根据护理模式,分为对照组(n=100)和观察组(n=100)。对照组采用常规护理干预,观察组采用综合快速康复护理干预。围手术期指标(手术时间、术后首次排气时间,住院时间)记录并比较两组。6h采用视觉模拟量表(VAS)对两组进行评分,12h,24h,手术后48小时,对患儿的疼痛程度进行定量评价。血清应激反应指数(皮质醇(Cor),去甲肾上腺素(NE),测定两组促肾上腺皮质激素(ACTH)水平。术后并发症的发生率,改善术后生活质量,比较两组患者的护理满意度。
    结果:手术时间,术后首次排气时间,观察组住院时间明显短于对照组(p<0.05),6h各时间点观察组患者的VAS评分均低于对照组,12h,24h,术后48h(p<0.05)。手术后一小时,血清Cor,NE,两组患者的ACTH水平明显高于术前,观察组的水平明显低于对照组(p<0.05)。治疗后,两组患者的生活质量评分均明显高于治疗前,且观察组患者的生活质量评分明显高于对照组(p<0.05)。观察组术后并发症发生率为3.00%(3/100),显著低于对照组(13.00%(13/100))(χ2=6.793,p=0.009)。观察组的护理满意度为95.00%(95/100),显著高于对照组(79.00%(79/100))(χ2=11.317,p=0.001)。
    结论:综合快速康复护理管理模式是一种能有效缓解LA对阑尾炎患儿应激反应及疼痛影响的干预措施。能有效降低术后并发症的发生率,提高患者的护理满意度,让阑尾炎患儿在手术后尽快康复,并能改善患者的生活质量。有助于提高整体临床疗效,处理工艺操作简单,相对安全可靠,具有很高的使用价值,值得在临床治疗中进一步推广。
    OBJECTIVE: Acute appendicitis is one of the most common causes of acute abdomen in pediatric surgery. The purpose of this study was to observe the effects of integrated rapid rehabilitation nursing in children with laparoscopic appendectomy (LA) during the perioperative period.
    METHODS: A total of 200 children with appendicitis who underwent LA in our hospital from January 2022 to January 2023 were retrospectively selected as the study subjects. According to the nursing mode, they were divided into a control group (n = 100) and an observation group (n = 100). The control group was treated with routine nursing intervention, and the observation group was treated with an integrated rapid rehabilitation nursing intervention. Perioperative indices (operation time, first postoperative exhaust time, length of hospital stay) were recorded and compared between the two groups. The visual analog scale (VAS) was used to score the two groups at 6 h, 12 h, 24 h, and 48 h after surgery, and the pain degree of the children was quantitatively evaluated. The levels of serum stress response indices (cortisol (Cor), norepinephrine (NE), and adrenocorticotropic hormone (ACTH)) in the two groups were measured. The incidence of postoperative complications, improvement of postoperative quality of life, and nursing satisfaction were compared between the two groups.
    RESULTS: The operation time, first postoperative exhaust time, and hospitalization time in the observation group were significantly shorter than those in the control group (p < 0.05), and the VAS scores of the patients in the observation group were lower than those in the control group at each time point of 6 h, 12 h, 24 h, and 48 h after surgery (p < 0.05). One hour after surgery, the serum Cor, NE, and ACTH levels of the two groups of patients were significantly higher than those before surgery, and the levels for the observation group were significantly lower than those of the control group (p < 0.05). After treatment, the quality of life scores of patients in both groups was significantly higher than before treatment, and the quality of life scores of patients in the observation group was significantly higher than that of the control group (p < 0.05). The postoperative complication rate of the observation group was 3.00% (3/100), which was significantly lower than that of the control group (13.00% (13/100)) (χ2 = 6.793, p = 0.009). The nursing satisfaction of the observation group was 95.00% (95/100), which was significantly higher than that of the control group (79.00% (79/100)) (χ2 = 11.317, p = 0.001).
    CONCLUSIONS: The integrated rapid rehabilitation nursing management mode is an intervention that can effectively alleviate the effects of LA on stress reactions and pain in children with appendicitis. It can effectively reduce the incidence of postoperative complications and improve the patient\'s nursing satisfaction, allowing children with appendicitis to recover as soon as possible after surgery, and can improve patients\' quality of life. It helps to improve the overall clinical efficacy, and the treatment process is simple to operate, relatively safe and reliable, has high use value, and is worthy of further promotion in clinical treatment.
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  • 文章类型: Journal Article
    目的:Lu的方法用于电视胸腔镜手术(LVATS),源自UVATS,是一种新颖的VATS手术方法,并对肺癌切除术进行了微创新。这项研究的目的是阐明安全性,可行性,和这种新型手术方法的疗效。
    方法:在3月之间接受了根治性胸腔镜肺叶切除术的非小细胞肺癌(NSCLC)患者的临床资料。2021年3月2022年,回顾性收集,并分析。根据在VATS操作过程中是否应用了Lu\'s方法,患者分为LVATS组和UVATS组。使用倾向评分(PS)匹配方法通过创建两组来减少选择偏差。生成PS后,完成1:1比率和最近邻分数匹配。围手术期变量,包括手术时间,术中失血,淋巴结站解剖,总排水量,排水持续时间,术后住院时间,疼痛评分(VAS,视觉模拟评分)在术后第一天(POD1)和第三天(POD3),术后并发症的发生率,对两组进行比较。对数据进行统计学分析,P<0.05定义为有统计学意义。
    结果:共确认182例患者,其中86例患者接受LVATS和96例UVATS。在这项回顾性研究中,倾向匹配产生了62对。围手术期无死亡病例。LVATS组患者的手术时间较短(88(75,106)VS122(97,144)min,P<0.001),术中出血量少(20(20,30)VS25(20,50)ml,P=0.021),缩短切口长度(2.50(2.50,2.50)VS3.00(3.00,3.50)cm,P<0.001),和更多的排水量(460(310,660)VS345(225,600)毫升,P=0.041)高于UVATS组患者。解剖的淋巴结位置没有显着差异(5(4,5)VS5(4,5),P=0.436),排水持续时间(3(3,4)VS3(3,4)天,P=0.743),术后住院时间(4(4,5)VS4(4,6)天,P=0.608),POD1上的VAS(4(4,4)VS4(4,4),P=0.058)和POD3(3(3,4)VS4(3,4),P=0.219),术后并发症发生率(P=0.521)。
    结论:Lu\的方法是一种安全可行的方法,用于电视胸腔镜下NSCLC的肺叶切除术。这种方法可以缩短手术时间,减少切口长度和术中失血量。
    OBJECTIVE: Lu\'s approach for video-assisted thoracoscopic surgery (LVATS), which derives from UVATS, is a novel surgical approach for VATS and carries out micro-innovation for lung cancer resection. The objective of this study is to elucidate the safety, feasibility, and efficacy of this novel surgical approach.
    METHODS: The clinical data of patients with non-small cell lung cancer (NSCLC) who underwent a curative thoracoscopic lobectomy between Mar. 2021 and Mar. 2022, were retrospectively collected, and analyzed. According to whether applied Lu\'s approach during the VATS operation, patients were divided into the LVATS group and the UVATS group. The propensity score (PS) matching method was used to reduce selection bias by creating two groups. After generating the PSs, 1:1 ratio and nearest-neighbor score matching was completed. Perioperative variables, including the operation time, intraoperative blood loss, lymph node stations dissected, total drainage volume, drainage duration, postoperative hospital stay, pain score (VAS, Visual Analogue Scale) on the postoperative first day (POD1) and third day (POD3), and incidence of postoperative complications, were compared between the two groups. The data were analyzed statistically with P<0.05 defined as statistically significant.
    RESULTS: A total of 182 patients were identified, among whom 86 patients underwent LVATS and 96 UVATS. Propensity matching produced 62 pairs in this retrospective study. There were no deaths during perioperative period. Patients in the LVATS group experienced a shorter operation time (88 (75, 106) VS 122 (97, 144)min, P <0.001), less intraoperative blood loss(20 (20, 30) VS 25 (20, 50)ml, P = 0.021), shorten incision length (2.50 (2.50, 2.50) VS 3.00 (3.00, 3.50)cm, P <0.001), and more drainage volume (460 (310, 660) VS 345 (225, 600)ml, P = 0.041) than patients in the UVATS group. There was not significant difference in the lymph node stations dissected(5 (4, 5) VS 5 (4, 5), P = 0.436), drainage duration (3 (3, 4) VS 3 (3, 4)days, P = 0.743), length of postoperative hospital stay (4 (4, 5) VS 4 (4, 6)days, P = 0.608), VAS on the POD1(4 (4, 4) VS 4 (4, 4), P = 0.058)and POD3 (3 (3, 4) VS 4 (3, 4), P = 0.219), and incidence of postoperative complications (P = 0.521) between the two groups.
    CONCLUSIONS: Lu\'s approach is a safe and feasible approach for video-assisted thoracoscopic surgery for the lobectomy of NSCLC. This approach can shorten surgical time, reduce incision length and intraoperative blood loss.
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  • 文章类型: Journal Article
    背景:气管内插管通常与术后并发症有关,例如喉咙痛不适和声音嘶哑,降低患者满意度,延长住院时间。喉罩(LMA)在减少气管插管相关的气道并发症中起着至关重要的作用。这项荟萃分析是为了确定LMA在电视胸腔镜手术(VATS)中的有效性和安全性。
    方法:PubMed,Embase,科克伦图书馆,从开始到2023年10月5日,搜索Medline和WebofScience数据库以寻找合格的研究。使用Cochrane工具(RoB2)评估RCT的可能性偏差。我们进行了敏感性分析和亚组分析以评估结果的稳健性。
    结果:本荟萃分析纳入了7篇文献。与气管插管相比,术后住院时间差异无统计学意义(SMD=-0.47,95%CI=-0.98-0.03,P=0.06),术中最低SpO2(SMD=0.00,95%CI=-0.49-0.49,P=1.00),低氧血症(RR=1.00,95%CI=0.26-3.89,P=1.00),术中最高PetCO2(SMD=0.51,95%CI=-0.12-1.15,P=0.11),手术野满意度(RR=1.01,95%CI=0.98-1.03,P=0.61),麻醉时间(SMD=-0.10,95%CI=-0.30-0.10,P=0.31),LMA组手术时间(SMD=0.06,95%CI=-0.13~0.24,P=0.55)和失血量(SMD=-0.13,95%CI=-0.33~0.07,P=0.21)。然而,LMA与较低的喉部不适发生率(RR=0.28,95%CI=0.17-0.48,P<0.00001)和术后声音嘶哑发生率(RR=0.36,95%CI=0.16-0.81,P=0.01)相关,气管插管与术后清醒时间延长有关(SMD=-2.19,95%CI=-3.49--0.89,P=0.001)。
    结论:与气管插管相比,LMA可有效降低VATS后咽喉不适和声音嘶哑的发生率,并能加速麻醉的恢复.对于某些特定的胸外科手术,LMA似乎是气管插管的替代方法。LMA在VATS中的疗效和安全性有待进一步探讨。
    BACKGROUND: Endotracheal intubation is often associated with postoperative complications such as sore throat discomfort and hoarseness, reducing patient satisfaction and prolonging hospital stays. Laryngeal mask airway (LMA) plays a critical role in reducing airway complications related to endotracheal intubation. This meta-analysis was performed to determine the efficacy and safety of LMA in video-assisted thoracic surgery (VATS).
    METHODS: The PubMed, Embase, Cochrane Library, Medline and Web of Science databases were searched for eligible studies from inception until October 5, 2023. Cochrane\'s tool (RoB 2) was used to evaluate the possibility biases of RCTs. We performed sensitivity analysis and subgroup analysis to assess the robustness of the results.
    RESULTS: Seven articles were included in this meta-analysis. Compared with endotracheal intubation, there was no significant difference in the postoperative hospital stay (SMD = -0.47, 95% CI = -0.98-0.03, P = 0.06), intraoperative minimum SpO2 (SMD = 0.00, 95% CI = -0.49-0.49, P = 1.00), hypoxemia (RR = 1.00, 95% CI = 0.26-3.89, P = 1.00), intraoperative highest PetCO2 (SMD = 0.51, 95% CI = -0.12-1.15, P = 0.11), surgical field satisfaction (RR = 1.01, 95% CI = 0.98-1.03, P = 0.61), anesthesia time (SMD = -0.10, 95% CI = -0.30-0.10, P = 0.31), operation time (SMD = 0.06, 95% CI = -0.13-0.24, P = 0.55) and blood loss (SMD =- 0.13, 95% CI = -0.33-0.07, P = 0.21) in LMA group. However, LMA was associated with a lower incidence of throat discomfort (RR = 0.28, 95% CI = 0.17-0.48, P < 0.00001) and postoperative hoarseness (RR = 0.36, 95% CI = 0.16-0.81, P = 0.01), endotracheal intubation was found in connection with a longer postoperative awake time (SMD = -2.19, 95% CI = -3.49 - -0.89, P = 0.001).
    CONCLUSIONS: Compared with endotracheal intubation, LMA can effectively reduce the incidence of throat discomfort and hoarseness post-VATS, and can accelerate the recovery from anesthesia. LMA appears to be an alternative to endotracheal intubation for some specific thoracic surgical procedures, and the efficacy and safety of LMA in VATS need to be further explored in the future.
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  • 文章类型: Journal Article
    目的比较机器人直肠癌手术(RRCS)和腹腔镜直肠癌手术(LRCS)对患者泌尿和性功能的保护作用。我们在PubMed进行了系统的搜索,WebofScience,科克伦图书馆,和Embase用于比较RRCS和LRCS对泌尿功能和性功能的影响的研究。国际前列腺症状评分(IPSS)使用国际勃起功能指数(IIEF-5)和女性性功能指数(FSFI)的五项版本评估患者的排尿功能和性功能。共有13项研究包括1964名患者,包括3项随机对照试验,5项回顾性队列研究,3项前瞻性队列研究,和2项倾向得分匹配的研究。959例患者接受了RRCS,1005例患者接受了LRCS。IPSS评分的统计学分析表明,术后3、6和12个月,RRCS组的排尿功能明显优于LRCS组[平均差异(MD),-1.06,95%CI-1.85至-0.28;和MD,-0.96,95%CI-1.60至-0.32;和MD,-1.09,95%CI-1.72至-0.46]。IIEF-5评分的统计学分析表明,在术后3、6和12个月,RRCS组的男性性功能明显优于LRCS组(MD,1.76,95%CI0.80至2.72;和MD,1.83,95%CI0.34至3.33;和MD,1.05,95%CI0.09至2.01)。FSFI评分的统计分析表明,术后6个月和12个月,RRCS组的女性性功能明显优于LRCS组(MD,2.86;95%CI1.38至4.35;和MD,4.19;95%CI1.85至6.54)。RRCS比LRCS更有利于保持直肠癌患者的泌尿和性功能。
    The purpose of the study was to compare the protective effects of robotic rectal cancer surgery (RRCS) and laparoscopic rectal cancer surgery (LRCS) on urinary and sexual function of patients. We conducted a systematic search in the PubMed, Web of Science, Cochrane Library, and Embase for studies comparing the impact of RRCS and LRCS on urinary function and sexual function. The International Prostate Symptom Score (IPSS), the five-item version of the International Index of Erectile Function (IIEF-5) and the Female Sexual Function Index(FSFI) were used to evaluate the urinary function and sexual function of patients. A total of 13 studies comprising 1964 patients were included in this meta-analysis, including 3 randomized controlled trials, 5 retrospective cohort studies, 3 prospective cohort studies, and 2 propensity score-matched studies. Nine hundred and fifty-nine patients underwent RRCS and 1005 patients underwent LRCS. Statistical analysis of the IPSS scores indicated urinary function was significantly better in the RRCS group than in the LRCS group at 3, 6 and 12 months postoperatively [mean difference (MD), - 1.06, 95% CI - 1.85 to - 0.28; and MD, - 0.96, 95% CI - 1.60 to - 0.32; and MD, - 1.09, 95% CI - 1.72 to - 0.46]. Statistical analysis of the IIEF-5 scores indicated male sexual function was significantly better in the RRCS group than in the LRCS group at 3, 6 and 12 months postoperatively (MD, 1.76, 95% CI 0.80 to 2.72; and MD, 1.83, 95% CI 0.34 to 3.33; and MD, 1.05, 95% CI 0.09 to 2.01). Statistical analysis of the FSFI scores indicated female sexual function was significantly better in the RRCS group than in the LRCS group at 6 and 12 months postoperatively (MD, 2.86; 95% CI 1.38 to 4.35; and MD, 4.19; 95% CI 1.85 to 6.54). RRCS is more favorable than LRCS in preserving the urinary and sexual function of patients with rectal cancer.
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  • 文章类型: Journal Article
    观察中药联合六子觉运动对早期肺癌术后患者生理症状及生活质量(QoL)的临床疗效。
    将一百八十三名接受电视胸腔镜手术(VATS)的肺癌患者分为中药治疗组(CM)或对照组(非中药治疗,NC),其中73人接受了中草药和六子爵疗法,110未接受中医综合治疗。使用1:2比例的倾向评分匹配(PSM)方法来平衡基线特征并评估CM在改善术后症状和QoL方面的功效。
    咳嗽,呼吸困难,胸痛,疲劳是VATS术后最常见的临床症状。除了胸痛,均与手术范围相关(P<0.05)。PSM之后,在匹配的队列中确定了165名患者,和性别的协变量,年龄,手术部位,两组间手术范围平衡(P>.05)。在全球健康状况领域,CM的QoL改善大于NC(6.06±15.83vs-1.06±14.68,P=.005)。就症状而言,咳嗽改善(1.69±3.15vs0.38±2.63,P=.006),爬楼梯时呼吸困难(-10.30±16.82vs-1.82±17.97,P=.004),CM的疼痛(-0.76±1.32vs-0.08±1.31,P=.002)优于NC。
    中医综合治疗(TCM)可以在VATS治疗癌症后的生理康复中提供治疗益处。
    UNASSIGNED: To observe the clinical efficacy of Chinese herbal medicine combined with Liuzijue exercise on the physiological symptoms and quality of life (QoL) in postoperative patients with early-stage lung cancer.
    UNASSIGNED: One hundred and eighty-three lung cancer patients who underwent video-assisted thoracoscopic surgery (VATS) were categorize into either a traditional Chinese medicine treatment group (CM) or a control group (non-traditional Chinese medicine treatment, NC), among whom 73 underwent Chinese herbal medicine and Liuzijue therapy, while 110 underwent no comprehensive treatment with traditional Chinese medicine. The propensity score matching (PSM) method with a 1:2 ratio was used to balance the baseline characteristics and evaluate the efficacy of CM in improving postoperative symptoms and QoL.
    UNASSIGNED: Cough, dyspnea, chest pain, and fatigue were the most common clinical symptoms after VATS. Except for chest pain, they were all correlated with the scope of operation (P < .05). After PSM, 165 patients were identified in the matched cohort, and the covariates of gender, age, operative site, and scope of operation were balanced between the 2 groups (P > .05). In the domain of global health status, the improvement in QoL in CM was greater than that in NC (6.06 ± 15.83 vs -1.06 ± 14.68, P = .005). In terms of symptoms, improvements in cough (1.69 ± 3.15 vs 0.38 ± 2.63, P = .006), dyspnea during climbing stairs (-10.30 ± 16.82 vs -1.82 ± 17.97, P = .004), and pain (-0.76 ± 1.32 vs -0.08 ± 1.31, P = .002) in CM were better than in NC.
    UNASSIGNED: Comprehensive treatment with traditional Chinese medicine (TCM) can provide therapeutic benefits in physiological rehabilitation after VATS for cancer.
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  • 文章类型: Case Reports
    这项研究检查了吲哚菁绿(ICG)荧光成像在腹腔镜下通过腹部入路辅助小儿腹膜后肿瘤切除术中的适用性。该研究于2023年5月至9月在广州妇女儿童医学中心进行,包括3例儿科病例,使用ICG荧光成像对其进行腹腔镜腹膜后肿瘤切除术.在每种情况下,ICG在手术前静脉内给药(0.3mg/kg),通过实时荧光成像实现重要血管结构的可视化。套管针的放置是通过“四孔”技术从健康侧在70度侧卧位引导的。手术成功完成,没有任何并发症。患者的病理分析确定了1例胚胎型Wilms肿瘤,一个没有N-MYC基因扩增的成熟型神经节神经母细胞瘤,和一个成熟的囊性畸胎瘤.研究结果表明,通过精心选择患者和熟练的手术执行,ICG荧光成像在儿童腹腔镜腹膜后肿瘤切除术中的应用是安全有效的。这种方法大大提高了关键血管的可视化,从而提高手术安全性。
    This study examined the applicability of indocyanine green (ICG) fluorescence imaging to assist the laparoscopic resection of retroperitoneal tumors in pediatric patients via an abdominal approach. Conducted prospectively at the Guangzhou Women and Children\'s Medical Center from May to September 2023, the research included three pediatric cases, for whom laparoscopic retroperitoneal tumor resections were performed utilizing ICG fluorescence imaging. In each case, ICG was intravenously administered (0.3 mg/kg) prior to surgery, enabling the visualization of vital vascular structures through real-time fluorescence imaging. The trocar\'s placement was guided by a \"four-hole\" technique from the healthy side in a 70-degree lateral decubitus position. The operations were accomplished successfully without any complications. Pathological analysis of the patients identified one case of Wilms tumor of the embryonal type, one ganglioneuroblastoma of the mature type without N-MYC gene amplification, and one mature cystic teratoma. The findings suggest that with careful patient selection and skilled surgical execution, the utilization of ICG fluorescence imaging in the laparoscopic resection of retroperitoneal tumors is both safe and effective in children. This approach significantly improves the visualization of critical blood vessels, thus enhancing surgical safety.
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  • 文章类型: English Abstract
    Surgery is the main means of achieving cure for colorectal cancer. Minimally invasive surgery, represented by laparoscopy and robotic surgery, has gradually become the mainstream approach for colorectal cancer at present. At the same time, the concept of surgery has appeared from simply emphasizing oncological radical treatment to emphasizing both radical treatment and function preservation. The quality control of colorectal cancer surgery includes the qualification admission system and assessment system, surgical approaches and indications, key surgical techniques (correct plain extension, lymph node dissection and resection range, nerve protection and function preservation, digestive tract reconstruction, and intraoperative prevention and treatment of complications). Unified and standardized quality control of surgery is not only a key factor in determining patient prognosis and quality of life, but also an important prerequisite for ensuring the accuracy of clinical trial.
    手术是结直肠癌获得根治的主要手段。以腹腔镜和机器人手术为代表的微创外科治疗已逐渐成为现阶段结直肠肿瘤手术的主流方式。与此同时,功能保留手术治疗理念的兴起,使人们从单纯强调肿瘤学根治转变为强调根治与器官功能保护两者并重的治疗目的。结直肠肿瘤手术实施的质量化控制包括手术资质准入制度、考核制度、手术方式和指征、手术关键技术(正确层面拓展、淋巴结清扫区域和切除范围、神经保护与功能保留以及消化道重建和术中并发症防治)等。统一规范的手术实施质量控制不仅是决定患者预后和生活质量的关键因素,也是确保相关临床研究结论准确性的重要前提。.
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  • 文章类型: English Abstract
    This study aims to explore the possibility and bottleneck of clinical translation for an artificial intelligence (AI) diagnosis system for bladder cancer based on cystoscopy.We retrospectively collected videos of 101 bladder cancer patients from January to November 2023, at Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Among these patients, with a median age of 63 years and 81.0% were male. The bladder cancer AI diagnosis system was utilized for diagnosis, and the accuracy of diagnoses from the videos was assessed. Additionally, a surgical evaluation scale was formulated to evaluate the quality of the videos, simulating clinical usage.The final test results showed a system sensitivity of 97.8%, a positive predictive value of 81.7%, specificity of 54.2%, and a negative predictive value of 92.3%. Furthermore, the surgical evaluation scale scores ranged from 3.96 to 4.69, indicating the feasibility of clinical application for this system.This study further quantitatively validated the accuracy of an artificial intelligence system using cystoscopy videos and assessed the potential for clinical application.
    本研究主要探讨基于膀胱镜的膀胱癌人工智能诊断系统(CAIDS)临床转化的可能性及瓶颈问题。回顾性收集2023年1~11月中山大学孙逸仙纪念医院的101例膀胱癌患者膀胱镜视频,患者年龄中位数为63岁,其中男性占比81.0%(82/101)。使用CAIDS进行诊断,并对视频的诊断准确性进行评估。同时制定手术评价量表,基于量表对视频质量进行评估,以模拟临床使用。使用膀胱镜视频来定量验证人工智能系统的准确性。最终测试结果系统灵敏度为97.8%,阳性预测值为81.7%,特异度54.2%,阴性预测值为92.3%。此外,手术评价量表评分在3.96~4.69,表明该系统具有临床推广的可行性。.
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