• 文章类型: Journal Article
    目的:机器人辅助手术是一种选择,进行结直肠手术的快速发展技术。此单中心分析的主要目的是比较选择性腹腔镜和机器人乙状结肠切除术治疗憩室疾病的手术创伤程度和费用。
    方法:从我们的前瞻性临床数据库中进行回顾性分析,以确定2016年1月至2020年12月在我们的三级转诊机构接受择期微创左侧结肠憩室切除术的所有年龄≥18岁的患者。
    结果:总计,83例(女31例,男52例)乙状结肠憩室炎患者行选择性微创乙状结肠切除术,其中42例接受了传统腹腔镜手术(LS)和41例机器人辅助手术(RS)。机器人辅助组(4,03mg/dL)术前和术后的平均C反应蛋白差异显着低于腹腔镜组(7.32mg/dL)(p=0.030)。同样,机器人的血红蛋白差异显著较低(p=0.039).LS组术后第一次排便发生在平均2.19天后,RS组的平均1.63天后(p=0.011)。总体费用的概述显示,机器人方法的每次手术和术后住院时间的总成本显着降低。6058€vs.6142€(p=0.014),不包括两个系统的购置和维护成本。
    结论:机器人结肠切除术治疗憩室病具有成本效益,与传统腹腔镜相比,术中创伤减少,术后C反应蛋白和血红蛋白漂移显著降低。
    OBJECTIVE: Robotic assisted surgery is an alternative, fast evolving technique for performing colorectal surgery. The primary aim of this single center analysis is to compare elective laparoscopic and robotic sigmoid colectomies for diverticular disease on the extent of operative trauma and the costs.
    METHODS: Retrospective analysis from our prospective clinical database to identify all consecutive patients aged ≥ 18 years who underwent elective minimally invasive left sided colectomy for diverticular disease from January 2016 until December 2020 at our tertiary referral institution.
    RESULTS: In total, 83 patients (31 female and 52 male) with sigmoid diverticulitis underwent elective minimally invasive sigmoid colectomy, of which 42 underwent conventional laparoscopic surgery (LS) and 41 robotic assisted surgery (RS). The mean C-reactive protein difference between the preoperative and postoperative value was significantly lower in the robotic assisted group (4,03 mg/dL) than in the laparoscopic group (7.32 mg/dL) (p = 0.030). Similarly, the robotic´s hemoglobin difference was significantly lower (p = 0.039). The first postoperative bowel movement in the LS group occurred after a mean of 2.19 days, later than after a mean of 1.63 days in the RS group (p = 0.011). An overview of overall charge revealed significantly lower total costs per operation and postoperative hospital stay for the robotic approach, 6058 € vs. 6142 € (p = 0,014) not including the acquisition and maintenance costs for both systems.
    CONCLUSIONS: Robotic colon resection for diverticular disease is cost-effective and delivers reduced intraoperative trauma with significantly lower postoperative C-reactive protein and hemoglobin drift compared to conventional laparoscopy.
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  • 文章类型: Journal Article
    背景:由于刚性手术器械的限制,传统的骨肿瘤开放手术有时会导致健康骨组织的过度切除。增加感染风险和恢复时间。
    方法:我们提出了一种具有4.5毫米直径可弯曲末端执行器的远程机器人,提供四个自由度,用于进入骨骼内部并进行肿瘤清创。临床前研究评估了有效性,临床情景,以及12个手术的可用性-6个幻影手术和6个牛骨手术。评估标准包括皮肤切口大小,骨窗大小,手术时间,去除率,转换为开放手术。
    结果:临床前研究表明,与传统的开放式刮宫术相比,机器人入路所需的切口大小和手术时间明显更短。
    结论:这项研究通过评估其临床前有效性和使用人类体模和牛骨肿瘤模型优化手术方法来验证所提出的系统的性能。
    BACKGROUND: Traditional open surgery for bone tumours sometimes has as a consequence an excessive removal of healthy bone tissue because of the limitations of rigid surgical instruments, increasing infection risk and recovery time.
    METHODS: We propose a remote robot with a 4.5-mm diameter bendable end-effector, offering four degrees of freedom for accessing the inside of the bone and performing tumour debridement. The preclinical studies evaluated the effectiveness, clinical scenario, and usability across 12 total surgeries-six phantom surgeries and six bovine bone surgeries. Evaluation criteria included skin incision size, bone window size, surgical time, removal rate, and conversion to open surgery.
    RESULTS: Preclinical studies demonstrated that the robotic approach requires significantly smaller incision size and procedure times than traditional open curettage.
    CONCLUSIONS: This study validated the performance of the proposed system by assessing its preclinical effectiveness and optimising surgical methods using human phantom and bovine bone tumour models.
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  • 文章类型: Journal Article
    骶尾部藏毛窦(SPS)是一种常见病,其特征是在骶尾部区域形成窦道或腔,通常含有头发和碎片。由于其慢性和复发性,手术管理在其治疗中起着至关重要的作用。这篇全面的综述探讨了SPS手术管理的进步和创新。回顾首先是对历史观点的概述,解剖学,和疾病的病理生理学,接下来是对当前手术技术的讨论,包括常规切除,襟翼程序,和微创方法。最近的进步,比如激光治疗,放射引导技术,和机器人辅助手术,也检查了。总结了结果研究的关键发现,包括术后疼痛管理,复发率,患者满意度。对临床实践的影响进行了讨论,强调保持最新外科技术和采用个性化治疗方法的重要性。提供了对未来研究的建议,强调需要比较不同的手术技术进行前瞻性研究,以及针对复发风险的微创方法和预测模型的研究。研究人员之间的合作,临床医生,行业合作伙伴对于推动SPS患者的创新和改善预后至关重要。
    Sacrococcygeal pilonidal sinus (SPS) is a common condition characterized by the formation of a sinus tract or cavity in the sacrococcygeal region, often containing hair and debris. Surgical management plays a crucial role in its treatment due to its chronic and recurrent nature. This comprehensive review explores the advancements and innovations in the surgical management of SPS. The review begins with an overview of the historical perspective, anatomy, and pathophysiology of the condition, followed by a discussion of current surgical techniques, including conventional excision, flap procedures, and minimally invasive approaches. Recent advancements, such as laser therapy, radiological guidance techniques, and robotic-assisted surgery, are also examined. The key findings from outcomes research are summarized, including postoperative pain management, recurrence rates, and patient satisfaction. The implications for clinical practice are discussed, emphasizing the importance of staying updated on the latest surgical techniques and adopting a personalized approach to treatment. Recommendations for future research are provided, highlighting the need for prospective studies comparing different surgical techniques, as well as research focusing on minimally invasive approaches and predictive models for recurrence risk. Collaboration among researchers, clinicians, and industry partners is essential to drive innovation and improve outcomes for patients with SPS.
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  • 文章类型: Case Reports
    我们报告了一例通过腹外缝合进行初次闭合修复的Morgagni疝。此外,我们回顾了腹腔镜修复的Morgagni疝病例,已知疝气缺损的大小,建立网格利用率的尺寸标准。一名87岁的妇女因右上腹部疼痛和呕吐来到我们医院。她没有腹部手术或外伤史。胸部X线摄影和计算机断层扫描(CT)显示Morgagni疝,胃和横结肠突出进入右胸腔。最初,由于她的年龄,对胃疝进行了内窥镜修复,这是成功的。然而,两天后她复发了,促使我们进行半紧急腹腔镜手术。腹腔镜检查显示有Morgagni缺陷,用网膜,横结肠,胃突出,胃因气腹而缩小。幸运的是,突出的器官可以很容易地重新定位到腹部,没有粘连。疝缺损测量为6x3厘米。我们用腹外缝合进行了初次闭合。未进行囊切除。手术持续98分钟。术后第1天开始口服,患者于术后第3天出院,无并发症。术后1个月胸部X线和CT扫描显示无复发,在9个月的随访检查中,患者仍无症状。根据我们的审查结果,原发性闭合是治疗小疝缺损的有效方法(经验法则:宽度,<4厘米;长度,<7厘米)。
    We report a case of a Morgagni hernia repaired by primary closure with an extra-abdominal suture. Moreover, we reviewed cases of laparoscopically repaired Morgagni hernia, in which the size of the hernia defect was known, to establish a size criterion for mesh utilization. An 87-year-old woman presented to our hospital with right upper abdominal pain and vomiting. She had no history of abdominal surgery or trauma. Chest radiography and computed tomography (CT) revealed a Morgagni hernia, with the stomach and transverse colon herniated into the right chest cavity. Initially, an endoscopic repair was performed for the herniated stomach due to her age, which was successful. However, she had a recurrence 2 days later, prompting us to perform a semi-emergent laparoscopic surgery. Laparoscopic examination revealed a Morgagni defect, with the omentum, transverse colon, and stomach herniated, with the stomach reduced by pneumoperitoneum. Fortunately, the herniated organs could be easily relocated into the abdomen with no adhesions. The hernia defect measured 6 x 3 cm. We performed primary closure with an extra-abdominal suture. No sac resection was performed. The operation lasted 98 min. Oral intake was initiated on postoperative day 1, and the patient was discharged on postoperative day 3 without complications. Chest radiography and CT scans at 1 month postoperatively showed no recurrence, and the patient remained asymptomatic at the 9-month follow-up examination. According to our review findings, primary closure is an efficient method for small hernia defects (rule of thumb: width, <4 cm; length, <7 cm).
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  • 文章类型: Journal Article
    背景:这项研究旨在实施一套可穿戴技术,以记录和分析外科医生在进行常规和机器人辅助腹腔镜手术期间的生理和人体工程学参数,比较外科手术过程中外科医生的人体工程学和压力水平。
    方法:本研究以两种不同的设置进行组织:模拟器任务和实验模型外科手术。参与的外科医生以随机方式在腹腔镜和机器人辅助手术中执行任务和外科手术。不同的可穿戴技术被用来记录外科医生的姿势,肌肉活动,手术期间的皮肤电活动和心电图信号。
    结果:模拟器研究涉及6名外科医生:3名经验丰富(>100例腹腔镜手术;36.33±13.65岁)和3名新手(<100例腹腔镜手术;29.33±8.39岁)。3名具有腹腔镜手术经验的不同外科专业的外科医生(>100例腹腔镜手术;37.00±5.29岁),但是没有手术机器人的经验,参加了实验模型研究。参与的外科医生在机器人辅助外科手术期间显示出增加的压力水平。总的来说,在机器人辅助手术中获得了改善的外科医生姿势,减少局部肌肉疲劳。
    结论:实施了一套可穿戴技术来测量和分析外科医生的生理和人体工程学参数。与传统的腹腔镜手术相比,机器人辅助手术对外科医生显示出更好的人体工程学结果。人体工程学分析使我们能够优化外科医生的表现并改善手术训练。
    BACKGROUND: This study aims to implement a set of wearable technologies to record and analyze the surgeon\'s physiological and ergonomic parameters during the performance of conventional and robotic-assisted laparoscopic surgery, comparing the ergonomics and stress levels of surgeons during surgical procedures.
    METHODS: This study was organized in two different settings: simulator tasks and experimental model surgical procedures. The participating surgeons performed the tasks and surgical procedures in both laparoscopic and robotic-assisted surgery in a randomized fashion. Different wearable technologies were used to record the surgeons\' posture, muscle activity, electrodermal activity and electrocardiography signal during the surgical practice.
    RESULTS: The simulator study involved six surgeons: three experienced (>100 laparoscopic procedures performed; 36.33 ± 13.65 years old) and three novices (<100 laparoscopic procedures; 29.33 ± 8.39 years old). Three surgeons of different surgical specialties with experience in laparoscopic surgery (>100 laparoscopic procedures performed; 37.00 ± 5.29 years old), but without experience in surgical robotics, participated in the experimental model study. The participating surgeons showed an increased level of stress during the robotic-assisted surgical procedures. Overall, improved surgeon posture was obtained during robotic-assisted surgery, with a reduction in localized muscle fatigue.
    CONCLUSIONS: A set of wearable technologies was implemented to measure and analyze surgeon physiological and ergonomic parameters. Robotic-assisted procedures showed better ergonomic outcomes for the surgeon compared to conventional laparoscopic surgery. Ergonomic analysis allows us to optimize surgeon performance and improve surgical training.
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  • 文章类型: Journal Article
    背景:Hugo™机器人辅助手术(RAS)系统是一种专为临床应用而设计的新型尖端机器人平台。然而,其在囊性肾肿瘤中的应用尚未得到彻底研究。在这种情况下,我们介绍了使用Hugo™RAS系统治疗囊性肾肿块的机器人辅助部分肾切除术(RAPN)的初步系列.方法:在2022年10月至2024年1月之间,在FondazionePoliclinico大学校园Bio-Medico进行了27例肾肿瘤的RAPN手术。我们的前瞻性委员会批准的数据集被查询为“囊性特征”(n=12)。收集围手术期数据。根据CKD-EPI公式计算eGFR。根据Clavien-Dindo分类报告术后并发症。根据EAU指南进行计算机断层扫描(CT)扫描以进行随访。Trifecta被定义为阴性手术边缘状态的共存,无Clavien-Dindo≥3级并发症,eGFR下降≤30%。结果:所有患者均成功接受了RAPN,无需转换或额外的端口放置。对接和控制台时间中位数为5.5(IQR,4-6)和79.5分钟(IQR,58-91分钟),分别。术中无并发症发生,以及乐器之间或与床边助手之间的冲突。记录了两个轻微的术后并发症(Clavien-DindoII)。出院时,血清肌酐和eGFR与术前值相当.只有一名患者(8.4%)显示出积极的手术切缘。三联成功率为91.7%。结论:使用新型Hugo™RAS系统对囊性肾肿块进行RPN可以安全有效地进行。这个机器人系统提供了令人满意的围手术期结果,保留肾功能,术后并发症低,三联率高。
    Background: The Hugo™ Robot-Assisted Surgery (RAS) system is a new cutting-edge robotic platform designed for clinical applications. Nevertheless, its application for cystic renal tumors has not yet been thoroughly investigated. In this context, we present an initial series of Robot-Assisted Partial Nephrectomy (RAPN) procedures carried out using the Hugo™ RAS system for cystic renal masses. Methods: Between October 2022 and January 2024, twenty-seven RAPN procedures for renal tumors were performed at Fondazione Policlinico Universitario Campus Bio-Medico. Our prospective board-approved dataset was queried for \"cystic features\" (n = 12). Perioperative data were collected. The eGFR was calculated according to the CKD-EPI formula. Post-operative complications were reported according to the Clavien-Dindo classification. Computed tomography (CT) scans for follow-up were performed according to the EAU guidelines. Trifecta was defined as the coexistence of negative surgical margin status, no Clavien-Dindo grade ≥ 3 complications, and eGFR decline ≤ 30%. Results: All the patients successfully underwent RAPN without the need for conversion or additional port placement. The median docking and console time were 5.5 (IQR, 4-6) and 79.5 min (IQR, 58-91 min), respectively. No intraoperative complications occurred, as well as clashes between instruments or with the bedside assistant. Two minor postoperative complications were recorded (Clavien-Dindo II). At discharge, serum creatinine and eGFR were comparable to preoperative values. Only one patient (8.4%) displayed positive surgical margins. The rate of trifecta achievement was 91.7%. Conclusions: RAPN for cystic renal masses using the novel Hugo™ RAS system can be safely and effectively performed. This robotic system provided satisfactory peri-operative outcomes, preserving renal function and displaying low postoperative complications and a high trifecta rate achievement.
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  • 文章类型: Journal Article
    尿路上皮癌的治疗随着腹腔镜或机器人手术等微创技术的引入而发展。挑战传统的开放手术方法,并导致非典型复发(AR)。AR包括端口部位转移和腹膜癌,然而,作者之间在精确分类方面仍然存在差异.AR的发病率在不同的研究中差异很大,在肌肉浸润性膀胱癌(MIBC)和上尿路上皮肿瘤(UTUC)中,范围从不到1%到超过10%。腹膜转移是MIBC患者中最常见的AR,而由于不同的手术方法,腹膜后转移在UTUC患者中普遍存在。AR表现的时间和生存结果与传统复发的时间密切相关,他们经常与之联系在一起。气腹逐渐被认为是ARs的病因,而与手术相关的危险因素越来越突出。目前与手术相关的主要原因包括手术期间肿瘤溢出和尿路侵犯,避免使用endo袋进行标本提取,和低手术经验。肿瘤分期等因素,组织学变异,和淋巴血管侵犯与ARs的风险相关,表明与肿瘤生物学密切相关。需要进一步的研究来更好地了解发病率,危险因素,特点,和AR的结果。
    The management of urothelial carcinoma has evolved with the introduction of minimally invasive techniques such as laparoscopic or robotic procedures, challenging the traditional approach of open surgery, and giving rise to atypical recurrences (ARs). ARs include port-site metastasis and peritoneal carcinomatosis, yet discrepancies persist among authors regarding their precise classification. Incidence rates of ARs vary widely across studies, ranging from less than 1% to over 10% in both muscle-invasive bladder cancer (MIBC) and upper tract urothelial tumor (UTUC). Peritoneal metastases predominate as the most common ARs in patients with MIBC, while retroperitoneal metastases are prevalent in those with UTUC due to differing surgical approaches. The timing of AR presentation and survival outcomes closely mirror those of conventional recurrences, with which they are frequently associated. Pneumoperitoneum has progressively been regarded less as the cause of ARs, while surgical-related risk factors have gained prominence. Current major surgical-related causes include tumor spillage and urinary tract violation during surgery, avoidance of endo bag use for specimen extraction, and low surgical experience. Factors such as tumor stage, histological variants, and lympho-vascular invasion correlate with the risk of ARs, suggesting a close association with tumor biology. Further studies are required to better understand the incidence, risk factors, characteristics, and outcomes of ARs.
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  • 文章类型: Journal Article
    背景:很少有原始文章描述使用单向解剖方法进行单孔胸腔镜节段切除术的围手术期结果。在这项回顾性研究中,我们评估了该手术的可行性和安全性.方法:本研究纳入了2019年2月至2022年12月在我科接受单孔胸腔镜肺段切除术的119例患者。将患者分为单向(U组,n=28)和常规(C组,n=91)夹层入路组。在单向(U)组中,优势肺血管和支气管在肺门处被横断,而没有解剖裂隙,在常规(C)组中,优势肺动脉暴露并在裂缝处分开。比较U组和C组的患者特征和围手术期结果。结果:两组之间简单和复杂节段切除术的比例在统计学上相似。手术时间较短(U组:110[轮距范围:90-140]min,C组:135[轮距范围:105-166]分钟,p=0.012),失血较少(U组:0[间隔范围:0-0]g,C组:0[轮距范围:0-50]g,U组p=0.003)比C组其他围手术期结局无显著组间差异.结论:单向解剖入路在单孔胸腔镜肺段切除术中是安全可行的,可以使手术更加顺利。
    Background: Few original articles describe the perioperative outcomes of uniportal thoracoscopic segmentectomy using a unidirectional dissection approach. In this retrospective study, we evaluated the feasibility and safety of this procedure. Methods: This study included 119 patients who underwent uniportal thoracoscopic segmentectomy in our department between February 2019 and December 2022. The patients were divided into unidirectional (group U, n = 28) and conventional (group C, n = 91) dissection approach groups. While the dominant pulmonary vessels and bronchi were transected at the hilum without dissecting a fissure in the unidirectional (U) group, the dominant pulmonary artery was exposed and divided at a fissure in the conventional (C) group. Patient characteristics and perioperative outcomes were compared between groups U and C. Results: The proportions of simple and complex segmentectomies were statistically similar between the groups. The operating time was shorter (group U: 110 [interqurtile range: 90-140] min, group C: 135 [interqurtile range: 105-166] min, p = 0.012) and there was less blood loss (group U: 0 [interqurtile range: 0-0] g, group C: 0 [interqurtile range: 0-50] g, p = 0.003) in group U than in group C. However, there were no significant intergroup differences in other perioperative outcomes. Conclusions: The unidirectional dissection approach in uniportal thoracoscopic pulmonary segmentectomy is safe and feasible and enables a smoother operation.
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  • 文章类型: Journal Article
    腹股沟疝(IHs)和破裂是马的一种相对常见的疾病,发生在小马驹(先天性)和成年(获得性)动物中。对40例进行腹腔镜手术以单独使用倒刺缝线或结合其他技术闭合VRs的患者进行了回顾性观察分析。信号,临床表现,手术,并获得随访数据。总的来说,使用倒刺缝线(单独或与其他方法结合)闭合了59个VR,6例预防性治疗,44例因获得性IH。在44例IH病例中,四个是非绞窄疝,三十岁时出现绞窄的小肠(二十八个获得性和两个先天性)。在这项研究中获得的结果表明,带倒刺缝线的腹腔镜疝修补术是一种有效且安全的外科手术,可以推荐作为治疗马腹股沟疝的标准做法。特别是当保留睾丸或保持生殖能力是优先事项时。
    Inguinal hernias (IHs) and ruptures are a relatively common condition in horses, occurring in foals (congenital) and adult (acquired) animals. A retrospective observational analysis was conducted on 40 cases that underwent laparoscopic surgery to close the VRs using barbed sutures alone or combined with other techniques. Signalment, clinical presentation, surgery, and follow-up data were obtained. In total, fifty-nine VRs were closed using barbed sutures (alone or in combination with other methods), with six cases performed prophylactically and forty-four due to acquired IH. Of the forty-four cases with IH, four were non-strangulated hernias, while thirty presented with strangulated small intestines (twenty-eight acquired and two congenital). The results obtained in this study suggest that laparoscopic hernioplasty with barbed sutures is an effective and safe surgical procedure that could be recommended as a standard practice for managing inguinal hernias in horses, particularly when sparing testicles or preserving reproductive capabilities is a priority.
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  • 文章类型: Journal Article
    背景:多门胸腔镜手术(mVATS)是手术治疗自发性气胸的标准方法。然而,单通道VATS(uVATS)已成为一种旨在将手术发病率降至最低的替代方法。这项研究旨在加强与mVATS相比,uVATS的安全性和有效性的证据。
    方法:从2004年1月至2020年12月,对接受原发性或继发性自发性气胸手术治疗的患者记录进行了资格评估。包括通过uVATS或mVATS进行胸膜切除术联合大泡切除术或根尖楔形切除术的患者。比较了通过uVATS或mVATS进行手术的患者的手术特征和术后数据。进行单变量和多变量分析以确定手术方式是否与任何并发症(主要结果)相关。主要并发症(即,Clavien-Dindo≥3),复发,延长住院时间或延长胸腔引流时间(次要结局).
    结果:共纳入212例患者。通过uVATS(n=71)和mVATS(n=141)治疗的患者气胸类型显着不同(继发性自发性;uVATS:54[76%],mVATS:79[56%];p=0.004)。两组之间的(主要)并发症和复发率没有显着差异。多变量分析显示,手术方法对主要或次要结局没有显著预测。
    结论:本研究表明,在自发性气胸的手术治疗中,uVATS在安全性和有效性方面不劣于mVATS。因此,uVATS方法有可能进一步改善自发性气胸的围手术期手术护理。
    BACKGROUND: Multiportal video-assisted thoracic surgery (mVATS) is the standard approach for the surgical treatment of spontaneous pneumothorax. However, uniportal VATS (uVATS) has emerged as an alternative aiming to minimize surgical morbidity. This study aims to strengthen the evidence on the safety and efficiency of uVATS compared to mVATS.
    METHODS: From January 2004 to December 2020, records of patients who had undergone surgical treatment for primary or secondary spontaneous pneumothorax were evaluated for eligibility. Patients who had undergone pleurectomy combined with bullectomy or apical wedge resection via uVATS or mVATS were included. Surgical characteristics and postoperative data were compared between patients who had undergone surgery via uVATS or mVATS. Univariable and multivariable analyses were performed to determine whether the surgical approach was associated with any complication (primary outcome), major complications (i.e., Clavien-Dindo ≥ 3), recurrence, prolonged hospitalization or prolonged chest drainage duration (secondary outcomes).
    RESULTS: A total of 212 patients were enrolled. Patients treated via uVATS (n = 71) and mVATS (n = 141) were significantly different in pneumothorax type (secondary spontaneous; uVATS: 54 [76%], mVATS: 79 [56%]; p = 0.004). No significant differences were observed in (major) complications and recurrence rates between both groups. Multivariable analyses revealed that the surgical approach was no significant predictor for the primary or secondary outcomes.
    CONCLUSIONS: This study indicates that uVATS is non-inferior to mVATS in the surgical treatment of spontaneous pneumothorax regarding safety and efficiency, and thus the uVATS approach has the potential for further improvements in the perioperative surgical care for spontaneous pneumothorax.
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