influencing factors

影响因素
  • 文章类型: Journal Article
    沟渠侵蚀是与土地退化和生态系统安全相关的严重全球环境问题。研究沟渠的影响因素并确定敏感性对环境可持续性具有重要意义。这项研究评估了空间分布,影响因素,四川省孙水河流域冲沟的易感性,中国西南地区。应用卫星图像支持的频率比率方法和具有不同影响因素的沟渠清单数据集(1614个沟渠头点)来评估沟渠的分布和敏感性。此外,沟壑头部点被分组到一个训练集(70%,1130点)和一个测试集(30%,484分)。空间分布结果表明,大部分冲沟位于盆地的中上部,以中等海拔(2100-3300米)为特征,陡坡(11.63-27.34°),废弃的农田,和坎比索尔斯的土壤,较少的冲沟位于以较低海拔为特征的下部,缓坡,植被覆盖率低。土地利用和土地覆盖对敏感性的影响显著大于其他因素,预测率为33.9,尤其是耕地弃置,而冲沟的发生也更经常发生在西南向的斜坡上。沟渠易感性突出表明,研究区域受影响非常低,低,中度,高,对这些沟渠的敏感性非常高,覆盖面积约16%,23%,32%,26%,分别占流域总量的3%,这表明61%的研究区域容易受到沟壑侵蚀。中度到高度敏感性位于上部和中部,与流域内冲沟的空间分布一致,并且在盆地的下部和上部都分布着非常高的敏感性(3%)。这些结果对土壤流失治理具有重要意义,土地规划,西南山区流域综合管理。
    Gully erosion is a serious global environmental problem associated with land degradation and ecosystem security. Examining the influencing factors of gullies and determining susceptibility hold significance in environmental sustainability. The study evaluates the spatial distribution, influencing factors, and susceptibility of gullies in the Sunshui River Basin in Sichuan Province, Southwest China. The frequency ratio method supported by satellite images and the gully inventory dataset (1614 gully head points) with different influencing factors were applied to assess the distribution and susceptibility of gullies. Additionally, gully head points were grouped into a training set (70%, 1130 points) and a test set (30%, 484 points). Spatial distribution results indicated that most gullies are located in the middle and upper part of the basin, characterized by moderate elevation (2100-3300 m), steep slopes (11.63-27.34°), abandoned farmland, and Cambisols soil, and fewer gullies are located in lower part characterized by lower elevation, gentle slopes, and low vegetation coverage. Land use and land cover influence on susceptibility is significantly greater than other factors with a prediction rate of 33.9, especially farmland abandonment, while the occurrence of gullies is also more often on southwest-orientated slopes. Gully susceptibility highlighted that the study area affected by the very low, low, moderate, high, and very high susceptibilities to these gullies covered an area of about 16%, 23%, 32%, 26%, and 3% of the total basin respectively, which indicates 61% of the study area is susceptible to gully erosion. Moderate to high susceptibility is situated in the upper and middle part, consistent with the spatial distribution of gullies in the basin, and very high susceptibility (3%) is distributed in both the lower and upper parts of the basin. These results have important implications for soil loss control, land planning, and integrated watershed management in the mountainous areas of Southwest China.
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  • 文章类型: Journal Article
    目的:通过志愿动机和自我效能感的系列多重中介模型,探讨主动性人格对护士社会责任感的影响机制。
    方法:对横断面和基于调查的研究进行进一步分析。
    方法:2023年6月,对来自四家医院的722名中国护士进行了一项研究。使用主动性人格量表收集数据,自我效能感量表,志愿者动机量表和护士社会责任感量表。采用结构方程模型分析了护士社会责任感与其相关因素之间的关系。
    结果:结构方程模型显示出良好的模型拟合。积极主动的人格,自我效能感和志愿者动机可以直接影响护士的社会责任感(β=.12,β=.04,β=.50,p<.05)。根据连锁调解效果的检验,通过自我效能感(Z=2.33,p<.05)和志愿者动机(Z=7.32,p<.05)的单一中介路径以及通过两个变量的连续中介路径(Z=3.33,p<.05),主动性人格是显着的。
    结论:主动人格可以激发护士的社会责任感。因此,促使护士更加积极主动,可以有效增强护士的社会责任感。
    本研究是在加强流行病学观察研究报告(STROBE)横断面研究清单之后报告的。
    本研究探讨了流行病结束时影响护士社会责任感的机制。该结果可能有助于维持高水平的护士社会责任的长期影响,并有助于为突发公共卫生事件建立常备劳动力。
    OBJECTIVE: To explore the mechanism of proactive personality influence on nurses\' sense of social responsibility through a serial multiple mediation model of volunteering motivation and self-efficacy.
    METHODS: Further analysis of a cross-sectional and survey-based study.
    METHODS: In June 2023, a study was conducted with 722 Chinese nurses from four hospitals. Data were collected using the Proactive Personality Scale, the Self-Efficacy Scale, the Motivation to Volunteer Scale and the Nurses\' Sense of Social Responsibility Scale. Structural equation modelling was used to analyse the relationship between nurses\' sense of social responsibility and its correlative factors.
    RESULTS: Structural equation modelling showed a good model fit. Proactive personality, self-efficacy and motivation to volunteer can directly influence nurses\' sense of social responsibility (β = .12, β = .04, β = .50, p < .05). According to the test of chained mediation effects, proactive personality was significant through a single mediation path of self-efficacy (Z = 2.33, p < .05) and motivation to volunteer (Z = 7.32, p < .05) and through successive mediation paths of both variables (Z = 3.33, p < .05).
    CONCLUSIONS: A proactive personality can motivate nurses\' social responsibility. Therefore, prompting nurses to be more proactive can effectively enhance nurses\' sense of social responsibility.
    UNASSIGNED: This study was reported following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies.
    UNASSIGNED: This study explored the mechanisms influencing nurses\' sense of social responsibility at the end of the epidemic. The results may inform the maintenance of high levels of long-term effects of nurses\' social responsibility and shed light on building a standing workforce for public health emergencies.
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  • 文章类型: Journal Article
    在人类健康风险评估中,估计水果中农药残留生物可及性对饮食暴露的影响是一项复杂的任务。这项研究调查了香蕉和芒果中十种常用和检测到的农药的生物可及性,以及影响它的因素,使用体外模型。在胃和肠阶段,在pH值为2.5和6.5时观察到最高的生物可及性,分别。大多数农药的生物可及性随着固液比的增加而显着降低。蛋白质和四种膳食成分(碳水化合物,蛋白质,脂质,和膳食纤维)可以显着降低农药的生物可得性9.89-48.32%(p<0.05)。四个人群在口腔和胃部阶段的生物可及性遵循成人/老人>儿童>婴儿的顺序,由于α-淀粉酶和胃蛋白酶的浓度降低。与芒果中的农药(11.68-87.57%)相比,香蕉中的农药通常表现出更高的生物可及性(18.65-82.97%)。生物可及性与目标农药的LogP值呈负相关,而生物可及性与初始农药浓度之间没有明确的关系。将生物可获得的农药浓度纳入风险评估可以将饮食风险估计值降低11.85-79.57%。根据生物可及性评估人类暴露于农药将大大提高风险评估的准确性。
    Estimating the impact of pesticide residue bioaccessibility in fruits on dietary exposure is a complex task in human health risk assessment. This research investigated the bioaccessibility of ten commonly used and detected pesticides in bananas and mangoes, as well as the factors influencing it, using an in vitro model. The highest bioaccessibility was observed at pH levels of 2.5 and 6.5 in the gastric and intestinal stages, respectively. Bioaccessibility decreased significantly with increasing solid/liquid ratios for most pesticides. The consumption of protein and four dietary components (carbohydrates, protein, lipids, and dietary fiber) could significantly reduce pesticide bioaccessibility by 9.89-48.32% (p < 0.05). Bioaccessibility in oral and gastric stages among four populations followed the order of adults/the elderly > children > infants, due to decreasing concentrations of α-amylase and pepsin. Pesticides in bananas generally exhibited a higher bioaccessibility (18.65-82.97%) compared to that in mangoes (11.68-87.57%). Bioaccessibility showed a negative correlation with the Log P values of the target pesticide, while no clear relationship was found between bioaccessibility and initial pesticide concentrations. Incorporating bioaccessible pesticide concentrations into risk assessments could lower dietary risk estimates by 11.85-79.57%. Assessing human exposure to pesticides based on bioaccessibility would greatly improve the accuracy of the risk assessment.
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  • 文章类型: Journal Article
    总的来说,2022年,德国约有6.31亿只肉鸡被屠宰。该评估包括大约的数据。2022年在德国运输的1.98亿只不同年龄和品种的肉鸡(占2022年所有肉鸡运输病例的31%)。这项研究的目的是分析2022年1月至2023年5月期间德国肉鸡运输(n=14,054)到屠宰场的死亡(DOA)率和可能的影响因素。因此,每次运输的动物总量之间的关系,运输的持续时间和距离,运输笼中的计划放养密度,统计评估了每日平均温度,一天中的时间和运输季节以及DOA率。结果显示平均DOA率为0.09%(SD0.09)。在中午(11:00至17:00)进行的运输显示出比在其他时间(一天分成6小时间隔)的运输更高的DOA率(p<0.05)。平均DOA率最高(0.10%)出现在秋季,接着是冬天,而春季和夏季的运输导致最低的DOA率(p<0.05)。总而言之,与其他欧洲国家的研究数据相比,德国相对较低的DOA率(%)表明其肉鸡运输的良好标准。
    In total, around 631 million broilers were slaughtered in Germany in 2022. This evaluation included data of approx. 198 million broilers of different ages and breeds that were transported in Germany in 2022 (31% of all cases of broiler chicken transport in 2022). The aim of this study was to analyze German broiler chicken transport (n = 14,054) to the slaughterhouse between January 2022 and May 2023 with regard to the dead-on-arrival (DOA) rate and the possible influencing factors. Therefore, the relation between the total amount of animals per transport, the duration and distance of the transport, the planned stocking density in the transport cages, the average daily temperature and time of day and season of the transport as well as the DOA rate were statistically evaluated. The results showed a mean DOA rate of 0.09% (SD 0.09). Transport conducted at midday (11:00 to 17:00) showed higher DOA rates (p < 0.05) than transport at other times (day split into 6 h intervals). The highest mean DOA rate (0.10%) was found in the fall, followed by the winter, while transport in the spring and summer resulted in the lowest DOA rate (p < 0.05). All in all, the relatively low DOA rate (%) in Germany indicates the good standard of their broiler transport compared to available data from research in other European countries.
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  • 文章类型: Journal Article
    具有百年历史的美拉德反应继续引起食品科学与技术领域研究人员的兴趣,和健康和医学科学。本章旨在简化和更新这个高度复杂的,多方面的话题。胺对羰基的简单亲核攻击引起一系列平行和随后的反应,同时发生,导致大量低质量和高质量的化合物。最近的研究集中在:(1)α-二羰基化合物的形成和转化,高反应性中间体,这些中间体对于开发所需的食品颜色和风味至关重要,但也导致有害的高级糖基化终产物(AGEs)的产生;(2)阐明不同食物中黑色素的结构及其对人体健康的有益影响;(3)AGEs对人体健康的有害影响。考虑到MR既有积极的后果,也有消极的后果,他们的控制强调前者并减轻后者,还正在认真研究使用现代技术和技术。
    The century old Maillard reactions continue to draw the interest of researchers in the fields of Food Science and Technology, and Health and Medical Sciences. This chapter seeks to simplify and update this highly complicated, multifaceted topic. The simple nucleophilic attack of an amine onto a carbonyl group gives rise to a series of parallel and subsequent reactions, occurring simultaneously, resulting into a vast array of low and high mass compounds. Recent research has focused on: (1) the formation and transformation of α-dicarbonyl compounds, highly reactive intermediates which are essential in the development of the desired color and flavor of foods, but also lead to the production of the detrimental advanced glycation end products (AGEs); (2) elucidation of the structures of melanoidins in different foods and their beneficial effects on human health; and (3) harmful effects of AGEs on human health. Considering that MRs have both positive and negative consequences, their control to accentuate the former and to mitigate the latter, is also being conscientiously investigated with the use of modern techniques and technology.
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  • 文章类型: Journal Article
    作为快速城市化的新产物,城市建设用地的蔓延可以客观反映城市土地利用效率,这对我国新城市建设具有重要意义。本研究旨在总结我国城市建设用地的扩张模式和利用效率现状,扩张的速度和趋势,并揭示导致建设用地扩张差异化分配的关键因素。也可为其他建设用地快速扩张的国家提供土地管理经验。结果显示如下。(1)我国建设用地扩张呈现"点-线-面"的演变格局,形成点状聚集的变化阶段,线性级数和平面展布。(2)我国建设用地呈现出无序扩散的特点,低利用率和低输出效率。扩张速度呈现东高西低的明显特征,主要集中在长江三角洲,珠江三角洲和京津冀城市群。上海,北京,深圳和广州的建设用地使用强度最高。在山东半岛和东部沿海地区,建设用地强度普遍较高。在新疆和西藏,建设用地利用强度相对较低。(3)城市经济水平,人口规模,产业结构,外资和土地政策对建设用地扩张的空间分布有显著影响。
    As a new product of rapid urbanization, the sprawl of urban construction land can objectively reflect urban land use efficiency, which is of great significance to China\'s new urban construction. This study aimed to summarize the expansion patterns and utilization efficiency of urban construction land in China from the perspectives of the status, speed and trends of expansion, and to uncover the key factors that lead to the differential distribution of the expansion of construction land. It can also provide land management experience for other countries with rapid expansion of construction land. The results show the following. (1) The expansion of China\'s construction land presents a \"point-line-plane\" pattern of evolution, forming changing stages of point-like aggregation, linear series and planar spread. (2) China\'s construction land shows the characteristics of disorderly spread, a low utilization rate and low output efficiency. The speed of expansion presents clear characteristics of being high in the east and low in the west, mostly concentrated in the Yangtze River Delta, Pearl River Delta and the Beijing-Tianjin-Hebei urban agglomeration. Shanghai, Beijing, Shenzhen and Guangzhou have the highest intensity of construction land use. In Shandong Peninsula and eastern coastal areas, the intensity of the construction land use is generally high. In Xinjiang and Xizang, the intensity of construction land use is relatively low. (3) The urban economic level, population size, industrial structure, foreign investment and land policies have significant effects on the spatial distribution of the expansion of construction land.
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  • 文章类型: Journal Article
    目的:探讨中国抚养孙子女的老年人抑郁症的潜在特征,并分析人群不同剖面特征的差异及其影响因素。
    方法:本研究采用2018年中国健康与退休纵向研究(CHARLS)。通过横断面研究,潜在轮廓分析用于分析抚养孙辈的老年人中抑郁症的潜在分类,并使用有序的多分类逻辑回归分析来评估每个因素对其不同分类的影响。
    结果:养育有抑郁症状的孙辈的1271名老年人分为三类:低水平抑郁症(55.4%),中度抑郁症(31.2%),和高度抑郁(13.4%)。有序多分类Logistic结果显示:性别,婚姻状况,养老保险,身体健康状况,生活满意度,IADL和IADL是抚养孙子女的老年人抑郁症状潜在分类的预测因子(P<0.05)。
    结论:在未来的初级保健中,在抚养孙辈的老年人中,针对不同的抑郁亚组提供有针对性的干预措施将更有意义.
    OBJECTIVE: To explore the latent profile of depression in older adults raising grandchildren in China, and to analyze the differences in the characteristics of the different profiles of the population and the factors influencing them.
    METHODS: This study utilized the 2018 China Health and Retirement Longitudinal Study (CHARLS). Through a cross-sectional study, the latent profile analysis was used to analyze the potential classification of depression among older adults raising grandchildren, and using ordered multi-categorical logistic regression analyses to assess the effects of each factor on their different classifications.
    RESULTS: The 1271 older adults raising grandchildren with depression symptoms were divided into three categories: low-level depression (55.4%), moderate-level depression (31.2%), and high-level depression (13.4%). Ordered multi-categorical Logistic results showed: Gender, marital status, pension insurance, physical health status, life satisfaction, and IADL were predictors of latent profile classification of depression symptoms in older adults raising grandchildren (P < 0.05).
    CONCLUSIONS: In the future of primary care, it will be more meaningful to provide targeted interventions for different subgroups of depression in older adults raising grandchildren.
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  • 文章类型: Journal Article
    背景:缩短院前急救医疗服务(EMS)响应时间对于挽救生命,降低突发疾病患者的死亡率和致残率至关重要。
    方法:利用重庆市主城区120调度指挥中心2021年救护车出行数据,分别对院前EMS响应时间和各构成进行描述性分析,然后采用logistic回归分析探讨影响因素。
    结果:重庆市主城区院前EMS响应时间中位数为14.52分钟,平均值是16.14分钟.44.89%的院前EMS响应时间超过15分钟。在高峰时段和高人口密度地区,响应时间更有可能超过此阈值。相反,在夜班期间观察到超过15分钟的较低概率,夏季和秋季,以及应急站密度高的地区。33.28%的制备时间大于3分钟,夜班和人口密度高的地区更有可能超过3分钟,而夏季和秋季,高人均国内生产总值地区的准备时间超过3分钟的可能性较低。45.52%的旅行时间大于11分钟,在高峰时段,夏天和秋天,人均GDP高的地区旅行时间可能超过11分钟,而夜班和急救站密度高的地区旅行时间超过11分钟的可能性较低。
    结论:影响院前EMS反应时间的主要因素是变化,交通场景,季节,人均GDP,应急站密度,和人口密度。相关部门可以设计有效的干预措施,通过资源分配和部门协调来减少响应时间,员工培训和工作安排优化,以及公众参与和教育,从而提高院前急救医疗服务的效率。
    BACKGROUND: Shortening the prehospital emergency medical services (EMS) response time is crucial for saving lives and lowering mortality and disability rates in patients with sudden illnesses.
    METHODS: Descriptive analyses of prehospital EMS response time and each component were conducted separately using ambulance trip data from the 120 Dispatch Command Centre in the main urban area of Chongqing in 2021, and then logistic regression analyses were used to explore the influencing factors.
    RESULTS: The median prehospital EMS response time in the main urban area of Chongqing was 14.52 minutes, and the mean was 16.14 minutes. 44.89% of prehospital EMS response time exceeded 15 minutes. Response time was more likely to surpass this threshold during peak hours and in high population density areas. Conversely, lower probabilities of exceeding 15 minutes were observed during the night shift, summer and autumn seasons, and areas with a high density of emergency station. 33.28% of preparation time was greater than 3 minutes, with the night shift and high population density areas more likely to be greater than 3 minutes, while the summer and autumn seasons, and high GDP per capita areas had a lower likelihood of having preparation time greater than 3 minutes. 45.52% of travel time was greater than 11 minutes, with peak hours, summer and autumn, and high GDP per capita areas more likely to had travel time greater than 11 minutes, while night shift and high emergency station density areas had a lower likelihood of travel time greater than 11 minutes.
    CONCLUSIONS: The primary factors influencing prehospital EMS response time were shifts, traffic scenarios, seasons, GDP per capita, emergency station density, and population density. Relevant departments can devise effective interventions to reduce response time through resource allocation and department coordination, staff training and work arrangement optimisation, as well as public participation and education, thereby enhancing the efficiency of prehospital emergency medical services.
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  • 文章类型: Journal Article
    背景:系统性红斑狼疮(SLE)是一种异质性自身免疫性疾病,具有不同的临床病程和预后,患者不仅身体受损,还有各种身体和精神合并症。越来越多的证据表明,SLE患者的精神障碍,会导致各种不良后果。
    目的:探讨SLE患者的心理健康特点及影响因素,阐明心理健康与人格特征、领悟社会支持的相关性。研究结果可为SLE患者的心理干预提供依据。
    方法:收集2020年6月至2022年6月海南医科大学第一附属医院收治的168例SLE患者的临床资料。采用症状自评量表(SCL-90)和领悟社会支持量表进行心理评估和相关分析,并将收集的数据与中国国家标准进行了比较。对影响心理健康的相关因素进行统计分析。一般信息问卷,修订后的生活方向测试,和简短的36项健康调查被用来评估乐观水平和生活质量(QoL),分别。
    结果:SLE患者躯体化评分较高,抑郁症,焦虑,和恐惧焦虑分量表优于国家常模(P<0.05)。总社会支持与SCL-90总分或各分量表之间存在相关性(P<0.05)。激素剂量和疾病活动指数(DAI)是影响患者心理健康的主要因素(P<0.05)。SLE患者乐观平均得分为14.36±4.42分,30例处于中、下水平。乐观水平与QoL得分呈正相关。
    结论:SLE患者有不同程度的心理障碍,受激素剂量和DAI的显著影响。在临床诊断和治疗期间,应密切监测患者的心理健康,并在建立积极的支持方面提供足够的支持,健康的思维和行为模式,提高他们的乐观水平和生活质量。
    BACKGROUND: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder with varied clinical courses and prognoses, not only did the patients suffer from physical impairment, but also various physical and psychiatric comorbidities. Growing evidence have suggested that mental disorders in SLE patients, can lead to various adverse consequences.
    OBJECTIVE: To explored the features and influencing factors of mental health in patients with SLE and clarifying the correlations between mental health and personality characteristics and perceived social support. The results would provide a basis for psychological intervention in patients with SLE.
    METHODS: The clinical data of 168 patients with SLE admitted at the First Affiliated Hospital of Hainan Medical University between June 2020 and June 2022 were collected. Psychological assessment and correlation analysis were conducted using the Symptom Checklist-90 (SCL-90) and Perceived Social Support Scale, and the collected data were compared with the national norms in China. The relevant factors influencing mental health were identified by statistical analysis. A general information questionnaire, the Revised Life Orientation Test, and Short-Form 36-Item Health Survey were employed to assess optimism level and quality of life (QoL), respectively.
    RESULTS: Patients with SLE obtained higher scores for the somatization, depression, anxiety, and phobic anxiety subscales than national norms (P < 0.05). A correlation was identified between total social support and total SCL-90 score or each subscale (P < 0.05). The factors significantly affecting patients\' mental health were hormone dosage and disease activity index (DAI) (P < 0.05). The average optimism score of patients with SLE was 14.36 ± 4.42, and 30 cases were in the middle and lower levels. A positive correlation was found between optimism level and QoL scores.
    CONCLUSIONS: Patients with SLE develop psychological disorders at varying degrees, which are significantly influenced by hormone dosage and DAI. Patients\' mental health should be closely monitored during clinical diagnosis and treatment and provided adequate support in establishing positive, healthy thinking and behavior patterns and improving their optimism level and QoL.
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  • 文章类型: Journal Article
    背景:老年白血病患者的心理问题日益突出,患者在诊断后可能面临污名化。然而,关于这些患者所经历的病耻感以及可能导致病耻感的因素的研究有限。
    目的:了解老年白血病患者确诊后的病耻感,并分析其影响因素。
    方法:使用问卷调查获得的临床数据进行回顾性分析,采访,和2020年6月至2023年6月衡阳医学院收治的老年白血病患者的病历。获得的数据包括参与者的基本人口统计信息,病史,白血病类型,白血病家族史,家庭月平均收入,养老金,和隐瞒疾病的倾向。社会影响量表(SIS)的中文版,感知社会支持量表(PSSS),焦虑自评量表(SAS),和抑郁自评量表(SDS)用于评估与病耻感相关的指标,社会支持,和心理健康状况。采用皮尔逊相关系数分析各量表得分之间的关系强度和方向,回归分析探讨老年白血病患者确诊后病耻感的相关因素。
    结果:分析了120例65-80岁白血病患者的数据。SIS和PSSS总分分别为43.60±4.07和37.06±2.87。SAS评分为58.35±8.32,SDS评分为60.58±5.97。老年白血病患者病耻感与社会支持呈负相关(r=-0.691,P<0.05),与焦虑、抑郁呈正相关(r=0.506、0.382,P<0.05)。年龄,教育水平,吸烟状况,家庭月平均收入,养老金,和隐瞒疾病的倾向与参与者的病耻感水平显着相关(P<0.05)。年龄,吸烟状况,社会支持,焦虑,抑郁是老年白血病患者确诊后污名化的预测因素(均P<0.05),决定系数(R2)为0.644,调整后的R2为0.607。
    结论:老年患者在被诊断为白血病后通常会经历污名化。年龄等因素,吸烟状况,社会支持,和心理健康可能会影响老年患者报告的耻辱经历。
    BACKGROUND: Psychological problems are becoming increasingly prominent among older patients with leukemia, with patients potentially facing stigmatization after diagnosis. However, there is limited research on the stigma experienced by these patients and the factors that may contribute to it.
    OBJECTIVE: To investigate the stigma faced by older patients after being diagnosed with leukemia and to analyze the potential influencing factors.
    METHODS: A retrospective analysis was conducted using clinical data obtained from questionnaire surveys, interviews, and the medical records of older patients with leukemia admitted to the Hengyang Medical School from June 2020 to June 2023. The data obtained included participants\' basic demographic information, medical history, leukemia type, family history of leukemia, average monthly family income, pension, and tendency to conceal illness. The Chinese versions of the Social Impact Scale (SIS), Perceived Social Support Scale (PSSS), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) were used to assess indicators related to stigma, social support, and mental health status. We used Pearson\'s correlation coefficient to analyze the strength and direction of the relationship between the scores of each scale, and regression analysis to explore the factors related to the stigma of older patients with leukemia after diagnosis.
    RESULTS: Data from 120 patients with leukemia aged 65-80 years were analyzed. The total score on the SIS and PSSS was 43.60 ± 4.07 and 37.06 ± 2.87, respectively. The SAS score was 58.35 ± 8.32 and the SDS score was 60.58 ± 5.97. The stigma experienced by older leukemia patients was negatively correlated with social support (r = -0.691, P < 0.05) and positively correlated with anxiety and depression (r = 0.506, 0.382, P < 0.05). Age, education level, smoking status, average monthly family income, pension, and tendency to conceal illness were significantly associated with the participants\' level of stigma (P < 0.05). Age, smoking status, social support, anxiety, and depression were predictive factors of stigmatization among older leukemia patients after diagnosis (all P < 0.05), with a coefficient of determination (R2) of 0.644 and an adjusted R2 of 0.607.
    CONCLUSIONS: Older patients commonly experience stigmatization after being diagnosed with leukemia. Factors such as age, smoking status, social support, and psychological well-being may influence older patients\' reported experience of stigma.
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