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Abstract：
BACKGROUND: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder with varied clinical courses and prognoses, not only did the patients suffer from physical impairment, but also various physical and psychiatric comorbidities. Growing evidence have suggested that mental disorders in SLE patients, can lead to various adverse consequences.
OBJECTIVE: To explored the features and influencing factors of mental health in patients with SLE and clarifying the correlations between mental health and personality characteristics and perceived social support. The results would provide a basis for psychological intervention in patients with SLE.
METHODS: The clinical data of 168 patients with SLE admitted at the First Affiliated Hospital of Hainan Medical University between June 2020 and June 2022 were collected. Psychological assessment and correlation analysis were conducted using the Symptom Checklist-90 (SCL-90) and Perceived Social Support Scale, and the collected data were compared with the national norms in China. The relevant factors influencing mental health were identified by statistical analysis. A general information questionnaire, the Revised Life Orientation Test, and Short-Form 36-Item Health Survey were employed to assess optimism level and quality of life (QoL), respectively.
RESULTS: Patients with SLE obtained higher scores for the somatization, depression, anxiety, and phobic anxiety subscales than national norms (P < 0.05). A correlation was identified between total social support and total SCL-90 score or each subscale (P < 0.05). The factors significantly affecting patients\' mental health were hormone dosage and disease activity index (DAI) (P < 0.05). The average optimism score of patients with SLE was 14.36 ± 4.42, and 30 cases were in the middle and lower levels. A positive correlation was found between optimism level and QoL scores.
CONCLUSIONS: Patients with SLE develop psychological disorders at varying degrees, which are significantly influenced by hormone dosage and DAI. Patients\' mental health should be closely monitored during clinical diagnosis and treatment and provided adequate support in establishing positive, healthy thinking and behavior patterns and improving their optimism level and QoL.
OBJECTIVE: To explored the features and influencing factors of mental health in patients with SLE and clarifying the correlations between mental health and personality characteristics and perceived social support. The results would provide a basis for psychological intervention in patients with SLE.
METHODS: The clinical data of 168 patients with SLE admitted at the First Affiliated Hospital of Hainan Medical University between June 2020 and June 2022 were collected. Psychological assessment and correlation analysis were conducted using the Symptom Checklist-90 (SCL-90) and Perceived Social Support Scale, and the collected data were compared with the national norms in China. The relevant factors influencing mental health were identified by statistical analysis. A general information questionnaire, the Revised Life Orientation Test, and Short-Form 36-Item Health Survey were employed to assess optimism level and quality of life (QoL), respectively.
RESULTS: Patients with SLE obtained higher scores for the somatization, depression, anxiety, and phobic anxiety subscales than national norms (P < 0.05). A correlation was identified between total social support and total SCL-90 score or each subscale (P < 0.05). The factors significantly affecting patients\' mental health were hormone dosage and disease activity index (DAI) (P < 0.05). The average optimism score of patients with SLE was 14.36 ± 4.42, and 30 cases were in the middle and lower levels. A positive correlation was found between optimism level and QoL scores.
CONCLUSIONS: Patients with SLE develop psychological disorders at varying degrees, which are significantly influenced by hormone dosage and DAI. Patients\' mental health should be closely monitored during clinical diagnosis and treatment and provided adequate support in establishing positive, healthy thinking and behavior patterns and improving their optimism level and QoL.
摘要：
背景：系统性红斑狼疮（SLE）是一种异质性自身免疫性疾病，具有不同的临床病程和预后，患者不仅身体受损，还有各种身体和精神合并症。越来越多的证据表明，SLE患者的精神障碍，会导致各种不良后果。
目的：探讨SLE患者的心理健康特点及影响因素，阐明心理健康与人格特征、领悟社会支持的相关性。研究结果可为SLE患者的心理干预提供依据。
方法：收集2020年6月至2022年6月海南医科大学第一附属医院收治的168例SLE患者的临床资料。采用症状自评量表(SCL-90)和领悟社会支持量表进行心理评估和相关分析,并将收集的数据与中国国家标准进行了比较。对影响心理健康的相关因素进行统计分析。一般信息问卷，修订后的生活方向测试，和简短的36项健康调查被用来评估乐观水平和生活质量(QoL)，分别。
结果：SLE患者躯体化评分较高，抑郁症,焦虑,和恐惧焦虑分量表优于国家常模(P<0.05)。总社会支持与SCL-90总分或各分量表之间存在相关性(P<0.05)。激素剂量和疾病活动指数（DAI）是影响患者心理健康的主要因素（P<0.05）。SLE患者乐观平均得分为14.36±4.42分,30例处于中、下水平。乐观水平与QoL得分呈正相关。
结论：SLE患者有不同程度的心理障碍，受激素剂量和DAI的显著影响。在临床诊断和治疗期间，应密切监测患者的心理健康，并在建立积极的支持方面提供足够的支持，健康的思维和行为模式，提高他们的乐观水平和生活质量。
目的：探讨SLE患者的心理健康特点及影响因素，阐明心理健康与人格特征、领悟社会支持的相关性。研究结果可为SLE患者的心理干预提供依据。
方法：收集2020年6月至2022年6月海南医科大学第一附属医院收治的168例SLE患者的临床资料。采用症状自评量表(SCL-90)和领悟社会支持量表进行心理评估和相关分析,并将收集的数据与中国国家标准进行了比较。对影响心理健康的相关因素进行统计分析。一般信息问卷，修订后的生活方向测试，和简短的36项健康调查被用来评估乐观水平和生活质量(QoL)，分别。
结果：SLE患者躯体化评分较高，抑郁症,焦虑,和恐惧焦虑分量表优于国家常模(P<0.05)。总社会支持与SCL-90总分或各分量表之间存在相关性(P<0.05)。激素剂量和疾病活动指数（DAI）是影响患者心理健康的主要因素（P<0.05）。SLE患者乐观平均得分为14.36±4.42分,30例处于中、下水平。乐观水平与QoL得分呈正相关。
结论：SLE患者有不同程度的心理障碍，受激素剂量和DAI的显著影响。在临床诊断和治疗期间，应密切监测患者的心理健康，并在建立积极的支持方面提供足够的支持，健康的思维和行为模式，提高他们的乐观水平和生活质量。
