influencing factors

影响因素
  • 文章类型: Journal Article
    本研究旨在评估心脏病患者运动恐惧症的全球患病率和潜在影响因素。在PubMed进行了全面搜索,Embase,WebofScience,PsycINFO,和Scopus数据库,以确定报告截至2024年1月心脏病患者运动恐惧症患病率及其影响因素的研究。采用随机效应模型来汇总患病率。通过亚组分析调查异质性来源,虽然运动恐惧症在不同地区的患病率存在差异,心脏病的类型,和性别进行了评估。此外,对运动恐惧症的影响因素进行了定性分析.这项研究纳入了来自六个国家的15项研究,14人提供了运动恐惧症患病率的数据,9人探索了其潜在的影响因素。研究结果表明,心脏病患者中运动恐惧症的总体患病率为61.0%(95%CI49.4-72.6%)。亚组分析显示,中上收入国家的患病率为71.8%(95%CI66.2-77.4%)。而在高收入国家,这一比例为49.9%(95%CI30.2-69.5%)。冠心病患者的患病率,心力衰竭,房颤为63.2%(95%CI45.2-81.3%),69.2%(95%CI57.6-80.8%),和71.6%(95%CI67.1-76.1%),分别。性别明智,男女运动恐惧症的患病率没有显着差异(52.2%vs.51.8%)。总共确定了24个潜在的运动恐惧症影响因素,受教育程度,月收入,焦虑,运动自我效能感是最受认可的。心脏病患者的运动恐惧症患病率很高,并且受多种因素的影响。必须尽早实施有针对性的预防措施,以减轻该人群中运动恐惧症的发生率。
    This study aims to assess the global prevalence of kinesiophobia and the potential influencing factors among patients with heart disease. A comprehensive search was conducted in PubMed, Embase, Web of Science, PsycINFO, and Scopus databases to identify studies reporting on the prevalence of kinesiophobia and its influencing factors in heart disease patients up to January 2024. A random-effects model was employed to aggregate prevalence rates. Heterogeneity sources were investigated through subgroup analysis, while differences in the prevalence of kinesiophobia across regions, types of heart disease, and gender were evaluated. Additionally, a qualitative analysis of the factors influencing kinesiophobia was performed. This research incorporated 15 studies from six countries, with 14 providing data on the prevalence of kinesiophobia and nine exploring its potential influencing factors. The findings indicated that the overall prevalence of kinesiophobia among heart disease patients was 61.0% (95% CI 49.4-72.6%). Subgroup analysis revealed that the prevalence in upper-middle-income countries was 71.8% (95% CI 66.2-77.4%), while it stands at 49.9% (95% CI 30.2-69.5%) in high-income countries. The prevalence rates among patients with coronary artery disease, heart failure, and atrial fibrillation were 63.2% (95% CI 45.2-81.3%), 69.2% (95% CI 57.6-80.8%), and 71.6% (95% CI 67.1-76.1%), respectively. Gender-wise, no significant difference was observed in the prevalence of kinesiophobia between men and women (52.2% vs. 51.8%). A total of 24 potential influencing factors of kinesiophobia were identified, with education level, monthly income, anxiety, and exercise self-efficacy being the most recognized. The prevalence of kinesiophobia in patients with heart disease is notably high and is influenced by a multitude of factors. Early implementation of targeted preventive measures is imperative to mitigate the incidence of kinesiophobia in this population.
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  • 文章类型: Journal Article
    运动恐惧症表示患者对身体活动或运动的过度和非理性的担忧,源于对疼痛损伤或再损伤的敏感性。心脏康复在心血管疾病患者的二级预防范围中起着关键作用,运动构成了这个方案的基石。然而,运动恐惧症的出现带来了巨大的挑战,降低患者对心脏康复方案的依从性,尤其是那些患有慢性心力衰竭的人。为了支持该队列中基于运动的康复计划,必须彻底理解诱发运动恐惧症的多方面因素。这篇综述试图描述慢性心力衰竭患者的运动恐惧症触发因素的流行证据和患病率。同时为未来的探索确定研究空白。
    采用范围审查方法,我们的调查收集了来自不同学术数据库的数据,包括Embase,PubMed,Scopus,CINAHL,WebofScience,Medline,Sinomed,CNKI,王凡,和VIP。
    经过全面评估,最终纳入9项符合纳入标准的研究。
    我们的研究结果强调了慢性心力衰竭患者运动恐惧症的明显患病率,主要受社会人口因素影响,心理和认知因素,疾病和治疗因素,以及生活方式和行为。有了这些见解,未来的干预措施可以量身定做,以减轻运动恐惧症的水平,在慢性心力衰竭患者中加强参与以运动为中心的心脏康复工作。
    UNASSIGNED: Kinesiophobia denotes an excessive and irrational apprehension towards physical activity or exercise among patients, stemming from a perception of susceptibility to painful injury or re-injury. Cardiac rehabilitation stands pivotal in the secondary prevention spectrum for individuals with cardiovascular ailments, with exercise constituting a cornerstone of this regimen. However, the emergence of kinesiophobia poses a formidable challenge, diminishing patient adherence to cardiac rehabilitation protocols, particularly among those grappling with chronic heart failure. To bolster exercise-based rehabilitation initiatives in this cohort, a thorough comprehension of the multifaceted factors precipitating kinesiophobia is imperative. This review endeavors to delineate prevailing evidence and prevalence concerning kinesiophobia triggers in chronic heart failure patients, while pinpointing research lacunae for future exploration.
    UNASSIGNED: Employing a scoping review methodology, our investigation culled data from diverse scholarly databases, including Embase, PubMed, Scopus, CINAHL, Web of Science, Medline, Sinomed, CNKI, Wangfan, and VIP.
    UNASSIGNED: After thorough evaluation, 9 studies that met the inclusion criteria were ultimately incorporated.
    UNASSIGNED: Our findings underscore a notable prevalence of kinesiophobia in chronic heart failure patients, predominantly influenced by socio-demographic factors, psychological and cognitive factors, disease and treatment factors, as well as lifestyle and behavior. Armed with these insights, future interventions can be tailored to mitigate kinesiophobia levels, fostering enhanced engagement in exercise-centric cardiac rehabilitation endeavors among patients grappling with chronic heart failure.
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  • 文章类型: Journal Article
    背景:患者体验在提高临床有效性和患者安全性方面起着至关重要的作用。确定影响患者体验的因素并提高医疗质量非常重要。
    目的:确定影响患者在医院病房体验的因素。
    方法:我们进行了包括六个数据库的系统综述;它们是PubMed,CINAHL,Embase,PsycInfo,ProQuest,还有Cochrane.如果符合纳入标准,则纳入研究。使用JBI检查表进行质量评估。我们使用生态模型的5个领域来组织和综合我们的发现,以全面了解影响该问题的多层次因素。
    结果:共纳入138项研究,并确定了164个因素。这些因子被整合到6个结构域中。除了一个(调查相关因素)以外的所有领域都可以映射到生态框架的属性上:内省,人际关系,机构,社区,和公共政策层面的因素。所有因素都对患者体验有混合影响。内部水平是指患者的个体特征。人际层面是指患者和医疗保健提供者之间的互动,例如护士所花费的照顾时间。制度层面是指组织特征,操作规则和条例,如医院规模和认证。社区层面是指组织之间的关系,机构,和限定边界内的信息网络,例如位于较大人口区域的医院。公共政策层面是指地方、state,国家,以及全球法律和政策,包括健康保险政策。第六个领域,调查相关因素,被添加到框架中,并包括调查响应率和调查响应时间等因素。
    结论:影响患者体验的因素是全面的,从内省到公共政策。提供者应采用整体和综合的观点来评估患者的体验,并制定针对具体情况的干预措施,以提高护理质量。PROSPERO注册号CRD42023401066。
    BACKGROUND: Patient experience plays an essential role in improving clinical effectiveness and patient safety. It\'s important to identify factors influencing patient experience and to improve quality of healthcare.
    OBJECTIVE: To identify factors that influence patient experience in hospital wards.
    METHODS: We conducted a systematic review including six databases; they were PubMed, CINAHL, Embase, PsycInfo, ProQuest, and Cochrane. Studies were included if they met the inclusion criteria. The JBI checklist was used to perform quality appraisal. We used 5 domains of the ecological model to organize and synthesize our findings to comprehensively understand the multi-level factors influencing the issue.
    RESULTS: A total of 138 studies were included, and 164 factors were identified. These factors were integrated into 6 domains. All domains but one (survey-related factors) could be mapped onto the attributes of the ecological framework: intrapersonal, interpersonal, institutional, community, and public policy level factors. All factors had mixed effect on patient experience. The intrapersonal level refers to individual characteristics of patients. The interpersonal level refers to interactions between patients and healthcare providers, such as the caring time spent by a nurse. The institutional level refers to organizational characteristics, rules and regulations for operations, such as hospital size and accreditation. The community level refers to relationships among organizations, institutions, and informational networks within defined boundaries, such as a hospital located in a larger population area. Public policy level refers to local, state, national, and global laws and policies, including health insurance policies. The sixth domain, survey-related factors, was added to the framework and included factors such as survey response rate and survey response time.
    CONCLUSIONS: The factors influencing patient experience are comprehensive, ranging from intrapersonal to public policy. Providers should adopt a holistic and integrated perspective to assess patient experience and develop context-specific interventions to improve the quality of care. PROSPERO REGISTRATION NUMBER CRD42023401066.
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  • 文章类型: Journal Article
    壳聚糖,一种源自几丁质的多功能氨基多糖生物聚合物,对各种病原微生物具有广谱抗微生物活性,包括革兰氏阴性菌和革兰氏阳性菌,以及真菌。由于它在药物中无处不在,食物,化妆品,化学品,和庄稼,它是一种有效的抗菌剂。然而,壳聚糖的抗菌性能受多种因素的影响,在文献中进行了广泛的研究和报道。这篇综述论文的目的是全面掌握壳聚糖及其衍生物的作用机制和确定变量的抗菌活性。本文首先提供了壳聚糖及其抗菌性能的简要背景,其次是了解作用机制和影响其活性的因素的重要性。“
    Chitosan, a versatile amino polysaccharide biopolymer derived from chitin, exhibits broad-spectrum antimicrobial activity against various pathogenic microorganisms, including gram-negative and gram-positive bacteria, as well as fungi. Due to its ubiquitous use in medications, food, cosmetics, chemicals, and crops, it is an effective antibacterial agent. However, the antimicrobial performance of chitosan is influenced by multiple factors, which have been extensively investigated and reported in the literature. The goal of this review paper is to present a thorough grasp of the mechanisms of action and determining variables of chitosan and its derivatives\' antibacterial activity. The article begins by providing a brief background on chitosan and its antimicrobial properties, followed by the importance of understanding the mechanism of action and factors influencing its activity\".
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  • 文章类型: Systematic Review
    背景:复杂的健康干预措施(CHIs)越来越多地用于公共卫生,临床研究和教育,以减轻全球疾病负担。众多的理论,已经开发了模型和框架(TMF)来支持CHI的实施。本系统综述旨在确定和批评与实施的三个特征有关的理论框架;适应性,可扩展性和可持续性(ASaS)。通过拆除组成理论,分析他们的组成部分概念,然后探索影响每个理论的因素,审查小组希望在实施CHIs时提供对注意事项的增强理解。
    方法:这篇评论搜索了PubMedMEDLINE,CINAHL,WebofScience,和谷歌学者研究复杂健康干预措施的TMF。叙事综合被用来检查可能影响适应性的因素,复杂健康干预措施的可扩展性和可持续性。
    结果:从五个数据库中检索到总共9763项研究(PubMed,MEDLINE,CINAHL,WebofScience,和谷歌学者)。删除重复项并应用资格标准后,35篇论文有资格入选。影响因素可以在外部环境(社会政治环境;领导资金,组织间网络),内部环境;(客户倡导;组织特征),干预特征(监督,监测和评估),和桥接因素(个人采用者或提供者特征)。
    结论:这项审查证实,已确定的TMFS通常不包括适应性的三个组成部分,可扩展性,和可持续性。目前的方法侧重于高收入国家或通用的“全世界”方法,很少有针对低收入和中等收入国家的框架。该评论为进一步探索适应性提供了起点,可扩展性和可持续性,在中低收入背景下。
    背景:未注册。
    BACKGROUND: Complex health interventions (CHIs) are increasingly used in public health, clinical research and education to reduce the burden of disease worldwide. Numerous theories, models and frameworks (TMFs) have been developed to support implementation of CHIs. This systematic review aims to identify and critique theoretical frameworks concerned with three features of implementation; adaptability, scalability and sustainability (ASaS). By dismantling the constituent theories, analysing their component concepts and then exploring factors that influence each theory the review team hopes to offer an enhanced understanding of considerations when implementing CHIs.
    METHODS: This review searched PubMed MEDLINE, CINAHL, Web of Science, and Google Scholar for research investigating the TMFs of complex health interventions. Narrative synthesis was employed to examine factors that may influence the adaptability, scalability and sustainability of complex health interventions.
    RESULTS: A total of 9763 studies were retrieved from the five databases (PubMed, MEDLINE, CINAHL, Web of Science, and Google Scholar). Following removal of duplicates and application of the eligibility criteria, 35 papers were eligible for inclusion. Influencing factors can be grouped within outer context (socio-political context; leadership funding, inter-organisational networks), inner context; (client advocacy; organisational characteristics), intervention characteristics (supervision, monitoring and evaluation), and bridging factors (individual adopter or provider characteristics).
    CONCLUSIONS: This review confirms that identified TMFS do not typically include the three components of adaptability, scalability, and sustainability. Current approaches focus on high income countries or generic \"whole world\" approaches with few frameworks specific to low- and middle-income countries. The review offers a starting point for further exploration of adaptability, scalability and sustainability, within a low- and middle-income context.
    BACKGROUND: Not registered.
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  • 文章类型: Journal Article
    许多抗生素通过废水释放到自然环境中。随着抗生素使用量的逐年增加,它对环境的有害影响正在升级。解决环境可持续性和人类健康需要对抗生素去除的显著关注。近年来,磁性生物炭(MBC)由于其优异的吸附和催化降解能力,在水处理中获得了广泛的应用。抗生素如磺胺甲恶唑(SMX),四环素(TC),环丙沙星(CIP),和其他通常表现出的MBC吸附能力范围为5mg/g至900mg/g。此外,MBC通常在60分钟内去除超过90%的这些抗生素。抗生素去除的有效性受到各种制备和修饰方法的显着影响。此外,磁性的结合使材料能够多次回收和重复使用,从而降低消费成本。本文讨论了使用MBC去除抗生素的最新研究。已经观察到,原材料和制备程序的选择的变化显着影响抗生素的去除,而涉及抗生素去除的机制仍然模棱两可。此外,已经注意到去除过程可能导致二次污染和高制备成本。因此,这篇综述全面概述了MBC在去除废水中抗生素的利用,包括修改等方面,准备,去除机制,以及影响去除的因素,并为抗生素开发提供建议。目的是为研究人员提供一个清晰的理解,以推进MBC材料领域。
    Numerous antibiotics are being released into the natural environment through wastewater. As antibiotic usage increases annually, its detrimental impact on the environment is escalating. Addressing environmental sustainability and human health requires significant attention towards antibiotic removal. In recent years, magnetic biochar (MBC) has gained widespread application in water treatment due to its exceptional adsorption and catalytic degradation capabilities. Antibiotics such as sulfamethoxazole (SMX), tetracycline (TC), ciprofloxacin (CIP), and others commonly exhibit an adsorption capacity by MBC ranging from 5 mg/g to 900 mg/g. Moreover, MBC typically removes over 90% of these antibiotics within 60 min. The effectiveness of antibiotic removal is significantly influenced by various preparation and modification methods. Furthermore, the incorporation of magnetism enables the material to be recycled and reused multiple times, thereby reducing consumption costs. This article discusses recent studies on antibiotic removal using MBC. It has been observed that variations in the selection of raw material and preparation procedures significantly affect antibiotic removal, while the mechanisms involved in antibiotic removal remain ambiguous. Additionally, it has been noted that the removal process may lead to secondary pollution and high preparation costs. Therefore, this review comprehensively outlines the utilization of MBC in the removal of antibiotics from wastewater, including aspects such as modification, preparation, removal mechanism, and factors influencing removal, and providing recommendations for antibiotic development. The aim is to offer researchers a clear understanding to advance the field of MBC materials.
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  • 文章类型: Systematic Review
    背景:《世界跌倒预防和管理指南》推荐多因素跌倒风险评估和多领域干预措施。为了成功实施这些干预措施,重要的是要了解影响实施的决定因素。
    方法:在2021年12月3日对该系统综述进行了文献检索,并于2023年4月3日在五个数据库中进行了更新:PubMed(包括MEDLINE),EMBASE(通过Embase.com),Cochrane中央对照试验登记册(通过Cochrane图书馆),WebofScience核心合集和CINAHL(通过EBSCO)。如果研究报告了影响社区老年人实施多因素跌倒风险评估和/或多领域干预措施的决定因素,则包括研究。社论,意见文件,针对一个人群(如帕金森)的系统评价和研究被排除.两名研究人员独立筛选了标题上的文章,摘要和全文。基于敏感性分析评价质量。“实践决定因素综合综合清单”用于对决定因素进行分类。
    结果:纳入29项研究。决定因素分为障碍(n=40)和促进因素(n=35)。必要资源的可用性是报告最多的决定因素。其他通常报告的决定因素是知识,老年人和医疗保健专业人员的意图/信念和动机,将干预措施融入当前的实践,通信,团队和推荐流程以及财务(DIS)激励。
    结论:确定障碍和促进因素对于选择适合具体情况的实施策略至关重要,并提高多因素跌倒风险评估和/或多领域干预措施的吸收和有效性。
    BACKGROUND: Multifactorial falls risk assessment and multidomain interventions are recommended by the World guidelines for falls prevention and management. To successfully implement these interventions, it is important to understand determinants influencing the implementation.
    METHODS: A literature search was conducted for this systematic review on the 3 December 2021 and updated on the 3 April 2023 in five databases: PubMed (including MEDLINE), EMBASE (via Embase.com), Cochrane Central Register of Controlled Trials (via Cochrane Library), Web of Science Core Collection and CINAHL (via EBSCO). Studies were included if they reported on determinants influencing the implementation of a multifactorial falls risk assessment and/or multidomain interventions in community-dwelling older people. Editorials, opinion papers, systematic reviews and studies focusing on one population (e.g. Parkinson) were excluded. Two researchers independently screened the articles on title, abstract and full text. The quality was evaluated based on a sensitivity analysis. \'The Comprehensive Integrated Checklist of Determinants of practice\' was used to categorise the determinants.
    RESULTS: Twenty-nine studies were included. Determinants were classified as barriers (n = 40) and facilitators (n = 35). The availability of necessary resources is the most reported determinant. Other commonly reported determinants are knowledge, intention/beliefs and motivation at the levels of older people and healthcare professionals, fitting of the intervention into current practice, communication, team and referral processes and financial (dis)incentives.
    CONCLUSIONS: Mapping of the barriers and facilitators is essential to choose implementation strategies tailored to the context, and to enhance the uptake and effectiveness of a multifactorial falls risk assessment and/or multidomain interventions.
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  • 文章类型: Journal Article
    再生水中药物和个人护理产品(PPCPs)的存在带来了持续的挑战,因为它们在灌溉期间渗入绿地土壤,导致逐步积累,带来相当大的生态风险。土壤中PPCPs积累的模拟和预测是主动生态风险管理的关键。然而,大多数研究工作主要集中在土壤中PPCPs的垂直运输机制上,忽略了将垂直和横向运输现象结合在一起的整体观点,除了积累动力学。为了解决这个差距,这项研究引入了一个全面的概念模型,该模型封装了垂直和横向运输的双重过程,再加上PPCPs在土壤环境中的积累。以绿地土壤的独特特性为基础,我们深入研究了控制PPCPs垂直和横向迁移的决定因素。此外,我们整合了现有的污染物传输模拟方法,旨在建立一个准确预测绿地土壤中PPCPs积累的综合模型。这种见解对于推断保护绿地土壤所需的再生水的排放阈值至关重要。为制定合理的灌溉策略提供信息,预测未来的环境风险。它为城市中水回用和污染控制领域更明智的决策提供了关键的理论基础。
    The presence of pharmaceuticals and personal care products (PPCPs) in reclaimed water introduces an ongoing challenge as they infiltrate green space soils during irrigation, leading to a gradual buildup that poses considerable ecological risks. The simulation and forecasting of PPCPs accumulation in soil are pivotal for proactive ecological risk management. However, the majority of research efforts have predominantly concentrated on the vertical transport mechanisms of PPCPs in the soil, neglecting a holistic perspective that integrates both vertical and lateral transport phenomena, alongside accumulation dynamics. To address this gap, this study introduces a comprehensive conceptual model that encapsulates the dual processes of vertical and lateral transport, coupled with accumulation of PPCPs in the soil environment. Grounded in the distinctive properties of green space soils, we delve into the determinants governing the vertical and lateral migration of PPCPs. Furthermore, we consolidate existing simulation methodologies for contaminant transport, aiming to establish a comprehensive model that accurately predicts PPCPs accumulation in green space soils. This insight is critical for deducing the emission threshold of reclaimed water necessary for the protection of green space soils, informing the formulation of rational irrigation strategies, and anticipating future environmental risks. It provides a critical theoretical basis for more informed decision-making in the realm of urban water reuse and pollution control.
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  • 文章类型: Journal Article
    有机磷酸酯(OPEs)是广泛使用的商业添加剂,但是它们的环境持久性和毒性引起了人们的严重关注,需要相关的修复策略。尽管有各种现有的OPE去除技术,迫切需要对它们进行全面筛查,以指导进一步的研究。这篇综述全面概述了用于从土壤和水中去除OPEs的技术,包括它们的相关影响因素,去除机制/降解途径,和实际应用。在对最新文献进行分析的基础上,我们得出的结论是(1)用于净化OPEs的方法包括吸附,水解,光解,高级氧化工艺(AOPs),活性污泥法,和微生物降解;(2)催化剂/添加剂的数量/特性等因素,pH值,无机离子浓度,和天然有机物(NOM)影响OPE的去除;(3)主要降解机制涉及活性氧(ROS)(包括•OH和SO4•-)诱导的氧化,降解途径包括水解,羟基化,氧化,脱氯,脱烷基化;(5)pH值的干扰,无机离子和NOM的存在可能会限制处理过程中的完全矿化,影响OPE去除技术的实际应用。这篇综述为现有和潜在的OPE去除方法提供了指导,为开发更有效,更环保的技术来处理土壤和水中的OPEs提供了理论基础和创新思路。
    Organophosphate esters (OPEs) are widely used commercial additives, but their environmental persistence and toxicity raise serious concerns necessitating associated remediation strategies. Although there are various existing technologies for OPE removal, comprehensive screening for them is urgently needed to guide further research. This review provides a comprehensive overview of the techniques used to remove OPEs from soil and water, including their related influencing factors, removal mechanisms/degradation pathways, and practical applications. Based on an analysis of the latest literature, we concluded that (1) methods used to decontaminate OPEs include adsorption, hydrolysis, photolysis, advanced oxidation processes (AOPs), activated sludge processes, and microbial degradation; (2) factors such as the quantity/characteristics of the catalysts/additives, pH value, inorganic ion concentration, and natural organic matter (NOM) affect OPE removal; (3) primary degradation mechanisms involve oxidation induced by reactive oxygen species (ROS) (including •OH and SO4•-) and degradation pathways include hydrolysis, hydroxylation, oxidation, dechlorination, and dealkylation; (5) interference from the pH value, inorganic ion and the presence of NOM may limit complete mineralization during the treatment, impacting practical application of OPE removal techniques. This review provides guidance on existing and potential OPE removal methods, providing a theoretical basis and innovative ideas for developing more efficient and environmentally friendly techniques to treat OPEs in soil and water.
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  • 文章类型: Journal Article
    背景:前列腺癌(PCa)治疗的摄取决定了病程,但受到几个因素的影响。这篇综述评估了影响尼日利亚PCa治疗吸收的因素,以期为提高治疗接受和PCa结局的政策和其他干预方法提供证据。
    方法:从Webofscience的电子数据库中检索到的相关文章的综述,PubMed,谷歌学者,非洲期刊在线和Hinari使用相关关键字进行。相关研究也是从已确定研究的书目参考文献中提取的。同行评审发表的文章报告了从2000吨2023年开始吸收或利用PCa治疗方案的任何相关因素,被认为是合格的,并提取了最相关的报告并将其纳入本综述。
    结果:观察到PCa治疗方案的摄取取决于几个因素,这些因素可以归类为经济因素,系统相关和患者相关因素。其中包括治疗方案的可用性,有针对性的选项的可用性,成本和财务限制,与系统相关的障碍,资金缺口和缺乏保险,患者的信念和感知,获得放射治疗服务和PCa筛查。
    结论:一些影响因素对PCa治疗的及时摄取构成障碍。向相关利益攸关方征求旨在减少或防止这些障碍的政策和战略。
    BACKGROUND: The uptake of prostate cancer (PCa) treatment determines the disease course, but is influenced by several factors. This review assessed the factors that influence the uptake of PCa treatments in Nigeria, with a view to providing evidence for policies and other interventional approaches that enhance treatment uptake and PCa outcomes.
    METHODS: A review of relevant articles retrieved from electronic databases of Web of science, PubMed, Google scholar, African Journals online and Hinari was performed using relevant keywords. Relevant studies were also extracted from the bibliographic references of the identified studies. Peer-reviewed published articles that reported any associated factor to the uptake or utilisation of PCa treatment options from 2000 to 2023 were considered eligible, and the most pertinent reports were extracted and incorporated into this review.
    RESULTS: The uptake of PCa treatment options was observed to be dependent on several factors which could be grouped as economic, system-related and patient-related factors. Among these were the availability of treatment options and targeted therapies, cost and financial constraints, system-related barriers, funding gaps and lack of insurance coverage, patients\' beliefs and perceptions, access to radiotherapy services and access to PCa screening.
    CONCLUSIONS: Several influencing factors posed barriers to the timely uptake of PCa treatment. Policies and strategies aimed at reducing or preventing these barriers are solicited from relevant stakeholders.
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