Underweight

体重不足
  • 文章类型: Journal Article
    从游牧到久坐的生活方式的转变带来了饮食的变化,而营养不足是定居的牧区家庭中的地方性疾病。本研究旨在探讨影响发育迟缓的潜在因素,体重不足,在马萨比特县浪费6-59个月的孩子,肯尼亚。在六个捕获牧区的病房进行了横断面家庭调查,农牧,和城市生计实践。采用多级抽样方法,394名6-59个月的儿童在得到看护者书面同意的情况下参加。在数据收集过程中使用了预先测试的问卷和人体测量法。人口特征被总结为手段和比例,而卡方和方差分析用于评估变量之间的关联。后向逻辑回归用于探索发育迟缓的预测因素,体重不足,浪费,分别。结果表明,年龄Z得分的平均身高,Z年龄体重评分,身高Z评分和体重分别为-1.51、1.54和1.02。发育迟缓的患病率,体重不足,浪费是38.1%,23.0%,和18.5%,分别。孩子的年龄,饮用水源,废物处理是影响儿童发育迟缓的主要因素。总之,与世界卫生组织建议的截止值相比,营养不良的患病率较高.水源卫生,和照顾者的收入是儿童营养不良的一些主要预测因素。发展机构需要把重点放在饮用水的供应上,使用厕所设施,除了在牧区护理人员中进行关于卫生补充喂养做法的营养教育。
    The transition from nomadism to sedentary lifestyle has introduced changes in diets and undernutrition is endemic among settled pastoral households. This study aimed to investigate the underlying factors affecting stunting, underweight, and wasting of children aged 6-59 months in Marsabit County, Kenya. A cross-sectional household survey was conducted in six wards capturing pastoral, agro-pastoral, and urban livelihood practices. Using multistage sampling method, 394 children aged 6-59 months participated with written consent from the caregivers. A pretested questionnaire and anthropometric measures were used during data collection. Population characteristics were summarized into means and proportions, while chi-square and analysis of variance were used to evaluate associations between variables. Backward logistic regressions were used to explore predictors of stunting, underweight, and wasting, respectively. The results showed that the mean Height for Age Z-score, Weight for Age Z-score, and Weight for Height Z-score were -1.51, 1.54, and 1.02, respectively. The prevalence of stunting, underweight, and wasting was 38.1%, 23.0%, and 18.5%, respectively. The age of child, source of drinking water, and waste disposal were some of the main factors influencing stunting among children. In conclusion, the prevalence of undernutrition was high compared to the World Health Organization recommended cutoffs. Water sources hygiene, and caregiver\'s income were some of the main predictors of undernutrition among children. Development agencies need to focus on the supply of potable water, access to toilet facilities, in addition to nutrition education on hygienic complementary feeding practices among pastoral caregivers.
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  • 文章类型: Journal Article
    埃塞俄比亚是撒哈拉以南非洲国家之一,育龄妇女体重不足很高,它是低出生体重的诱因,早产,并降低对感染的抵抗力。可怜的水,卫生,和卫生(WASH)和被致病微生物污染的饮用水导致营养不良。因此,这项研究旨在评估ArbaMinch健康和人口监测站(HDSS)的育龄妇女WASH与体重不足之间的关系,埃塞俄比亚南部。在ArbaMinchHDSS进行了一项基于社区的横断面研究,南埃塞俄比亚,2022年4月至5月。育龄妇女被纳入研究。使用预测试问卷和检查表收集数据。通过调整社会人口统计学特征,进行多变量分析以评估WASH指标与女性体重不足状况的关联。使用具有95%置信区间的调整赔率比(AOR)来评估该关联。育龄妇女体重过轻和超重/肥胖的患病率分别为7.82%(95%CI:5.60,10.81)和12.32%(95%CI:9.50,15.83),分别。厕所卫生和使用与体重不足显着相关。与使用不清洁厕所或没有厕所设施的人相比,使用清洁厕所的人体重不足的几率为0.43(95%CI:0.20,0.92)。使用清洁厕所设施与育龄妇女体重不足呈负相关。从WASH组件中,厕所的利用和保持厕所清洁使用需要专注于降低育龄妇女体重不足的风险。
    Ethiopia is one of the sub-Saharan African countries where underweight among women of reproductive age is high, and it is predisposing to low birth weight, preterm birth, and reduced resistance to infections. Poor water, sanitation, and hygiene (WASH) and drinking water polluted with disease-causing microorganisms lead to undernutrition. Therefore, this study aimed to assess the association between WASH and underweight among women of reproductive age at Arba Minch Health and Demographic Surveillance Site (HDSS), Southern Ethiopia. A community-based cross-sectional study was conducted at Arba Minch HDSS, South Ethiopia, from April to May 2022. Women of reproductive age were included in the study. Data were collected using a pre-tested questionnaire and checklist. Multivariate analysis was conducted to assess the association separately for WASH indicators with underweight status of the women by adjusting for sociodemographic characteristics. Adjusted Odds Ratio (AOR) with a 95% confidence interval was used to assess the association. The prevalence of underweight and overweight/obesity among women of reproductive age was 7.82% (95% CI: 5.60, 10.81) and 12.32% (95% CI: 9.50, 15.83), respectively. Latrine hygiene and use were significantly associated with being underweight. The odds of being underweight among those who use clean latrine were 0.43 (95% CI: 0.20, 0.92) compared to those who use unclean latrine or do not have toilet facilities. The utilization of clean latrine facilities is negatively associated with being underweight among women of reproductive age. From WASH components, latrine utilization and keeping the latrine clean to use need to get focused on reducing the risk of being underweight among women of reproductive age.
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  • 文章类型: Journal Article
    巴基斯坦营养不良的双重负担(DBM)是影响上学儿童的日益关注的问题,以同一人群中营养不良和营养不良并存为标志。主要影响因素包括饮食习惯的转变,社会经济地位,以及快速城市化导致的生活方式变化。关注木尔坦,巴基斯坦,该研究旨在评估体重不足和超重学生的比例,同时确定与这种发病率相关的危险因素和社会人口统计学特征。目的是指导未来的健康干预措施,以应对这一多维健康挑战。材料与方法本研究,采用描述性横断面研究设计,通过访谈和人体测量从女青少年学生那里收集数据。从代表不同城市和农村环境的综合学校名单中随机选择了300名参与者。测量参与者的体重和身高以计算他们的体重指数(BMI),将它们归类为体重不足,正常体重,和超重群体。通过访谈问卷收集相关危险因素。使用IBMSPSSStatisticsforWindows分析收集的数据,26.0版(2019年发布;IBMCorp.,Armonk,纽约,美国),结果根据社会经济分层,饮食,和社会心理因素,并在不同的体重类别中进行比较。结果该研究收集了300名学生的数据,揭示了社会经济地位之间的相关性,饮食习惯,BMI。父母的职业显著影响营养状况,劳动者的子女主要属于正常和体重不足的类别。诸如快餐和牛奶或乳制品消费的频率等饮食习惯与营养状况显着相关。同伴或老师对体重和户外运动参与的评论等心理社会因素也影响了学生的营养状况。然而,家庭收入等因素,视频游戏时间,宠物在家中的存在与营养状况没有显着关联。结论这项研究说明了社会经济地位之间的多方面联系,饮食习惯,木尔坦学童的体重指数,巴基斯坦,强调全面干预的必要性。
    Introduction The double burden of malnutrition (DBM) in Pakistan is a rising concern affecting school-going children, marked by coexisting under- and over-nutrition within the same population. Key influences include shifts in dietary habits, socioeconomic status, and lifestyle changes due to rapid urbanization. With a focus on Multan, Pakistan, the study seeks to assess the proportion of underweight and overweight students while identifying the risk factors and sociodemographic characteristics associated with this incidence. The aim is to guide future health interventions addressing this multidimensional health challenge. Materials and methods This study, adopting a descriptive cross-sectional research design, collected data from female teenage students through interviews and anthropometric measurements. A total of 300 participants were randomly selected from a comprehensive school list representing diverse urban and rural settings. Participants\' weight and height were measured to calculate their body mass index (BMI), categorizing them into underweight, normal weight, and overweight groups. The relevant risk factors were collected through an interview questionnaire. Collected data were analyzed using IBM SPSS Statistics for Windows, Version 26.0 (Released 2019; IBM Corp., Armonk, New York, United States), with the results stratified according to socioeconomic, dietary, and psychosocial factors and compared across different weight categories. Results The study collected data from 300 students, revealing a correlation between socioeconomic status, dietary habits, and BMI. Parental occupation significantly affected nutritional status, with children of laborers primarily falling within normal and underweight categories. Dietary habits like frequency of fast food and milk or dairy consumption showed notable associations with nutritional status. Psychosocial factors such as peer or teacher comments about weight and outdoor sports participation also influenced the students\' nutritional status. However, factors like family income, video game hours, and the presence of pets at home did not show significant associations with nutritional status. Conclusions The study illustrates a multi-faceted association between socioeconomic status, dietary habits, and BMI among schoolchildren in Multan, Pakistan, emphasizing the need for comprehensive interventions.
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  • 文章类型: Journal Article
    背景不发达国家的儿童免疫计划可以改善儿童的生长和营养状况,防止生长延迟,同时保护儿童免受传染病和满足生长规范。本研究旨在评估疫苗接种状况对扩大免疫接种中心12-18个月儿童人体测量指标的影响,并比较具有完整和不完整疫苗接种状况的儿童的人体测量指标。方法这项研究是在KalaShahKaku的农村卫生中心进行的,巴基斯坦,从2023年11月到2023年12月。纳入12-18个月的儿童,并记录他们的疫苗接种情况。身高和体重使用世界卫生组织生长图测量。数据采用描述性统计、卡方检验和Fisher精确检验进行分析。P值<0.05被认为是统计学上显著的。结果本研究访问疫苗接种部位的110名儿童的平均年龄为16.36个月±2.415。有28名(25.5%)发育迟缓的儿童。在研究中,17.6(16%)参与者体重不足,和15.95(14.5%)被浪费。孩子们,79%的人接受了所有推荐的疫苗接种。在疫苗接种和营养状况之间发现统计学上显著(p<0.05)的关联。结论本研究强调了疫苗接种在促进儿童健康和营养方面的重要意义。降低发育迟缓的风险,并确保公平获得疫苗接种服务和全面的医疗保健干预措施。这有助于减轻营养不良负担,促进最佳生长。促进全球健康和发展目标。
    Background Childhood immunization programs in underdeveloped nations can improve children\'s growth and nutritional status and prevent growth delays while protecting against infectious diseases and meeting growth norms. This study aimed to assess the impact of vaccination status on the anthropometric indices of children aged 12-18 months at an Expanded Programme on Immunization vaccination center and compare the anthropometric indices of growth in children with complete and incomplete vaccination statuses. Methodology This study was conducted at the rural health center in Kala Shah Kaku, Pakistan, from November 2023 to December 2023. Children aged 12-18 months were enrolled and their vaccination status was recorded. Height and weight were measured using World Health Organization growth charts. The data were analyzed using descriptive statistics and chi-square and Fisher\'s exact tests. A p-value <0.05 was considered statistically significant. Results The mean age of the 110 children who visited the vaccination site for this study was 16.36 months ± 2.415. There were 28 (25.5%) stunted children. In the study, 17.6 (16%) participants were underweight, and 15.95 (14.5%) were wasted. Of the children, 79% had received all recommended vaccinations. A statistically significant (p < 0.05) association was found between vaccination and nutritional status. Conclusions This study emphasizes the significance of vaccination in promoting child health and nutrition, reducing stunting risk, and ensuring equitable access to vaccination services and comprehensive healthcare interventions. This can help mitigate the malnutrition burden and promote optimal growth, contributing to global health and development goals.
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  • 文章类型: Journal Article
    加纳脑瘫(CP)儿童的营养流行病学知识有限,因此需要进行全面调查,以提高对该人群营养不良的认识。
    我们旨在描述加纳CP儿童营养不良的流行病学。
    该研究使用了作为加纳CP登记册(GCPR)一部分收集的数据。GCPR是对加纳18岁以下CP儿童的基于机构的监测。在2018年10月至2020年4月之间,N=455名患有CP的儿童进行了登记。收集了关于(I)体重的数据,长度或高度,CP儿童的中上臂围;(ii)社会人口统计学特征;(iii)运动类型和地形,粗大运动功能分类系统水平(GMFCS);(iv)相关损伤;(v)每个孩子的教育和康复状况。进行描述性和双变量分析。
    评估时注册儿童的平均和标准偏差年龄为5.9±4.1岁,42.1%为女性。三分之二的儿童有≥一种形式的营养不良(体重不足或体重严重不足:38.9%,发育不良或严重发育不良:51.2%,瘦或严重瘦:23.8%)。在调整后的分析中,低母亲教育,GMFCS-IV,语言障碍和癫痫显著增加了参与儿童营养不良的几率(分别为aOR:2.6[95%CI:1.3-5.4];2.2[95%CI:1.0-4.8];2.0[95%CI:1.1-3.6];2.9[95%CI:1.1-7.5]).
    高营养不良率表明加纳迫切需要营养干预措施和转化研究,以改善儿童的营养状况并预防不良结局。
    我们的研究为加纳CP儿童制定指南和循证干预措施提供了重要的数据和框架。
    UNASSIGNED: Limited knowledge on nutritional epidemiology in Ghanaian children with Cerebral Palsy (CP) necessitates a comprehensive investigation for an improved understanding of malnutrition in this population.
    UNASSIGNED: We aimed to describe the epidemiology of malnutrition among children with CP in Ghana.
    UNASSIGNED: The study used data collected as part of the Ghana CP Register (GCPR). The GCPR is an institution-based surveillance of children with CP aged < 18 years in Ghana. Between October 2018 and April 2020, N = 455 children with CP were registered. Data were collected on (i) weight, length or height, mid-upper-arm-circumference of children with CP; (ii) socio-demographic characteristics; (iii) motor type and topography, gross motor function classification system level (GMFCS); (iv) associated impairments; (v) educational and rehabilitation status for each child. Descriptive and bivariate analyses were performed.
    UNASSIGNED: Mean and standard deviation age of the registered children at assessment was 5.9 ± 4.1 years, and 42.1% were female. Two-thirds of the children had ≥ one form of undernutrition (underweight or severely underweight: 38.9%, stunted or severely stunted: 51.2%, thin or severely thin: 23.8%). In the adjusted analysis, low maternal education, GMFCS-IV, speech impairment and epilepsy significantly increased the odds of undernutrition among participating children (aOR: 2.6 [95% CI:1.3-5.4]; 2.2 [95% CI:1.0-4.8]; 2.0 [95% CI:1.1-3.6]; 2.9 [95% CI:1.1-7.5] respectively).
    UNASSIGNED: The high malnutrition rate indicates an urgent need for nutrition interventions and translational research to improve nutritional status and prevent adverse outcomes among children with CP in Ghana.
    UNASSIGNED: Our study contributes important data and a framework to develop guidelines and evidence-based interventions for children with CP in Ghana.
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  • 文章类型: Journal Article
    背景:儿童的营养状况是其整体健康和福祉的关键指标。公共卫生仍然面临营养不良的挑战,尤其是在全球的发展中国家。在卢旺达,约33%的五岁以下儿童患有慢性营养不良。许多因素,比如贫穷,文盲,糟糕的WASH做法,不当的儿童喂养做法,医疗保健不足,是营养不良的主要原因。这项研究旨在评估婴儿和幼儿的喂养方式,WASH,粮食安全,以及他们与卢旺达西部和南部省份五岁以下儿童营养状况的关系。
    方法:采用基于社区的横断面研究设计,研究了影响Karongi439个家庭五岁以下儿童营养状况的因素,Nyabihu,和卢旺达尼亚马加贝地区。这项研究评估了贫血,发育迟缓,体重不足,浪费指标,并使用SPSS25版对收集的数据进行分析。
    结果:研究结果表明,在接受调查的儿童中,29.2%(128)被确定为发育不良,5.9%(26)体重不足,2.3%(10)患有消瘦症,20.9%(31)有贫血。与这些情况相关的因素包括较大的家庭规模[AOR=2.108;95%CI(1.016-4.371)],与发育迟缓呈正相关。此外,来自户主60岁以上家庭的儿童更有可能表现出发育迟缓[AOR=4.809;95%CI(1.513,15.283)].此外,家庭饮食多样性评分高与体重过轻呈正相关[AOR=6.061;95%CI(1.535,23.942)].
    结论:家庭特征,如大小,饮食多样性,户主的年龄影响儿童的营养状况。改善这些条件将提高儿童的营养状况。
    BACKGROUND: The state of a child\'s nutrition is a critical indicator of their overall health and wellbeing. Public health still faces challenges from undernutrition, especially in developing nations across the globe. In Rwanda, around 33% of children aged under five years suffer from chronic undernutrition. Many factors, such as poverty, illiteracy, poor WASH practices, improper child feeding practices, and insufficient healthcare, are the leading causes of undernutrition. The study aims to assess infant and young child feeding practices, WASH, food security, and their association with the nutritional status of children under five years in Rwanda\'s Western and Southern provinces.
    METHODS: A community-based cross-sectional study design was applied to study factors affecting the nutritional status of children under five years in 439 households in the Karongi, Nyabihu, and Nyamagabe districts of Rwanda. The study assessed anemia, stunting, underweight, and wasting indicators, and collected data was analyzed using SPSS version 25.
    RESULTS: The study findings indicate that among the children surveyed, 29.2% (128) were identified as stunted, 5.9% (26) were underweight, 2.3% (10) suffered from wasting, and 20.9% (31) had anemia. Factors associated with these conditions included larger household size [AOR = 2.108; 95% CI (1.016-4.371)], positively associated with stunting. Additionally, children from households where the head was above 60 years old were more likely to exhibit stunting [AOR = 4.809; 95% CI (1.513, 15.283)]. Furthermore, a high household dietary diversity score was positively linked to being underweight [AOR = 6.061; 95% CI (1.535,23.942)].
    CONCLUSIONS: Household characteristics like size, dietary diversity, and the age of the household head affect children\'s nutritional status. Improving these conditions would enhance children\'s nutritional status.
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  • 文章类型: Journal Article
    全球营养不良被认为是一个主要的健康和营养问题。营养不良导致全球约45%的儿童死亡。印度儿童体重不足的患病率是世界上最高的。我们的儿童还承受着营养不良的双重负担。
    了解印度北部农村社区六个月至三岁儿童营养不良的患病率和决定因素。
    一项针对Ludhiana地区农村地区6个月至3岁儿童的社区横断面研究,方法和材料:从30,000名人口中确定了6个月至3岁年龄段的662名儿童,并将其纳入研究。关于这些孩子的所有相关信息都是从家庭文件夹中收集的。使用改良的UdaiPareek量表(MUP)评估社会经济地位。
    将收集的数据输入MSExcel中,并使用SPSS版本26和WHOAnthroSurveyAnalyzer进行分析。
    在662名儿童中,16%体重不足。2-3岁类别中几乎50%的儿童体重不足。研究人群中发育迟缓的患病率为20.7%,超重的患病率为4.8%。低社会经济地位儿童体重不足的患病率高于高社会经济地位儿童(P=0.000)。出生顺序与体重不足病例增加之间存在显着关联(P=0.000)。
    儿童营养不良的原因是复杂的,涉及多种因素。需要大力监测,以便及早发现2-3岁儿童的营养不良情况。孕产妇教育的改善将改善儿童的营养状况。
    UNASSIGNED: Worldwide malnutrition is identified as a major health and nutrition problem. Undernutrition contributes to an estimated 45% of child deaths globally. The prevalence of underweight among children in India is among the highest in the world. Our children also bear a tremendous double burden of malnutrition.
    UNASSIGNED: To find out the prevalence and determinants of malnutrition among six months to three-year-old children in the rural community of Northern India.
    UNASSIGNED: A community-based cross-sectional study conducted among children aged six months to three years in a rural area of Ludhiana district, Methods and Material: A total of 662 children in the age group of six months to three years from a population of 30,000 were identified and included in the study. All the relevant information regarding these children was collected from family folders. Socioeconomic status was assessed using the modified Udai Pareek scale (MUP).
    UNASSIGNED: The data collected was entered in MS Excel and was analyzed using SPSS version 26 and WHO Anthro Survey Analyzer.
    UNASSIGNED: Out of 662 children, 16% were underweight. Almost 50% of the children in the two-three years category were underweight. The prevalence of stunting in the study population was 20.7% and that of overweight was 4.8%. The prevalence of underweight was higher in children of low socioeconomic status than in children from upper socioeconomic status (P = 0.000). There was a significant association between birth order and increasing cases of underweight (P = 0.000).
    UNASSIGNED: The causes of malnutrition in children are complex and involve multiple factors. There is a need for vigorous monitoring for early detection of malnutrition for children aged two-three years. The improvement of maternal education will improve the nutritional status of the child.
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  • 文章类型: Journal Article
    背景:有大量研究解释了女性就业和家庭财富状况对减少营养不良的单独影响。然而,我们的研究揭示了产妇就业和家庭财富对巴基斯坦3岁以下儿童营养不良的综合影响.
    方法:使用来自2017-2018年巴基斯坦人口与健康调查的1093名三岁以下儿童的样本,采用二元逻辑模型来评估影响儿童营养不良的因素。
    结果:我们的结果表明,居住在某些地区(巴基斯坦)的特定年龄(3岁)的儿童和最近的腹泻发作增加了营养不良的风险。相反,中等和高等教育,获得改善的水源,和卫生设施降低了巴基斯坦三岁以下儿童营养不良的机会。孕产妇就业与家庭财富之间的相互作用表明,孕产妇就业显着降低了发育迟缓的风险,体重不足,在平均水平中浪费,富有,最富有的家庭;然而,它没有促进贫困家庭和贫困家庭的儿童营养。值得注意的是,不管母亲是否受雇,富有和富有的财富地位降低了发育迟缓的风险,体重不足,和浪费。
    结论:在克服营养不良方面,孕产妇就业对中等收入家庭的贡献显著。然而,在富裕和最富有的家庭中,与孕产妇就业相比,财富地位发挥了更重要的作用。这表明,虽然就业在家庭资源中起着支持作用,财富状况总体上在减少营养不良方面更具影响力。
    BACKGROUND: There is an abundance of studies explaining the separate impact of female employment and household wealth status in reducing malnutrition. However, our study has unraveled the combined impact of maternal employment and household wealth on undernutrition among children under three in Pakistan.
    METHODS: Using a sample of 1093 children under three years of age from the Pakistan Demographic and Health Survey 2017-2018, a binary logistic model was employed to gauge factors influencing the children\'s undernutrition.
    RESULTS: Our results indicated that children up to a certain age (three years old) with residence in certain regions (Pakistan) and recent episodes of diarrhea had an increased risk of undernutrition. Conversely, secondary and higher maternal education, access to improved water sources, and sanitation facilities lowered the chances of undernutrition in children under three in Pakistan. The interaction between maternal employment and household wealth showed that maternal employment significantly lowered the risk of stunting, being underweight, and wasting among the average, rich, and richest households; however, it did not contribute to child nutrition among the poorer and poor households. Notably, regardless of whether the mother was employed, the wealth status of being rich and richest reduced the risk of stunting, being underweight, and wasting.
    CONCLUSIONS: In overcoming undernutrition, maternal employment significantly contributed to middle-income households. However, in the richer and richest households, the wealth status played a more crucial role compared to the maternal employment. This indicates that while employment plays a supportive role in household resources, the wealth status is overall more influential in reducing undernutrition.
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  • 文章类型: Journal Article
    表征中国RA患者与美国患者的BMI,并检查其与中国患者关节损伤的关系。
    首先对来自真实世界中国RA人群的1318名患者进行性别分层,然后分别与1999-2018年美国国家健康和营养检查调查的一名美国RA患者进行年龄匹配。BMI数据,我们收集了纳入时的双侧手部X线照片和危险因素,但没有美国患者的X线照片.采用Logistic回归分析评估中国患者BMI与影像学关节损伤(RJD)的相关性。
    中国患者的BMI[(加权)中位数为21.8vs29.8kg/m2;P<0.001]和体重不足的患病率(15.2%vs1.1%;P<0.05)明显低于美国患者。中国体重过轻患者(BMI<18.5)的改良总Sharp评分(中位数17vs10)和关节间隙狭窄(JSN)子评分(中位数6vs2)(均P<0.05)高于正常体重患者(BMI≥18.5-<24)。在控制了混淆之后,连续BMI与RJD[校正患病率比值比(OR)0.90(95%CI0.85,0.96)]和JSN[校正患病率OR0.92(95%CI0.87,0.96)]呈横断面负相关;体重过轻与正常体重与RJD[校正患病率OR2.14(95%CI1.37,3.35)]和JSN[校正患病率OR1.77(95%CI1.10,2.84)相关.
    低BMI和体重过轻与中国RA患者的关节损伤相关,尤其是JSN,提示识别体重不足患者并关注体重增加以防止关节损伤的临床重要性。
    UNASSIGNED: To characterize BMI in Chinese patients with RA vs US patients and examine its association with joint damage in Chinese patients.
    UNASSIGNED: Each of the 1318 patients from a real-world Chinese RA population was first stratified by gender and then individually age-matched with one American RA patient from the US National Health and Nutritional Examination Survey 1999-2018. Data on BMI, bilateral hand radiographs and risk factors at enrolment were collected but radiographs were unavailable for the American patients. Logistic regression was used to evaluate the association of BMI with radiographic joint damage (RJD) in Chinese patients.
    UNASSIGNED: Chinese patients had a significantly lower BMI [(weighted) median 21.8 vs 29.8 kg/m2; P < 0.001] and a higher prevalence of being underweight (15.2% vs 1.1%; P < 0.05) than their American counterparts. Underweight Chinese patients (BMI <18.5) had higher modified total Sharp scores (median 17 vs 10) and joint space narrowing (JSN) subscores (median 6 vs 2) (both P < 0.05) than normal-weight patients (BMI ≥18.5-<24). After controlling for confounding, continuous BMI was cross-sectionally negatively associated with RJD [adjusted prevalence odds ratio (OR) 0.90 (95% CI 0.85, 0.96)] and JSN [adjusted prevalence OR 0.92 (95% CI 0.87, 0.96)]; being underweight vs normal weight was associated with RJD [adjusted prevalence OR 2.14 (95% CI 1.37, 3.35)] and JSN [adjusted prevalence OR 1.77 (95% CI 1.10, 2.84)].
    UNASSIGNED: Low BMI and being underweight were cross-sectionally associated with joint damage in Chinese RA patients, especially JSN, suggesting the clinical importance of identifying underweight patients and focusing on weight gain to prevent joint damage.
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  • 文章类型: Journal Article
    妊娠糖尿病(GDM)影响全球近15%的妊娠,并且在全球范围内呈上升趋势。虽然这种增长被认为主要来自超重和肥胖,正常和体重不足的女性也会受到影响,特别是在低收入和中等收入国家。然而,非超重女性的GDM仍未得到充分研究。因此,我们调查了全球正常和体重不足女性的患病率.
    在OvidMEDLINE进行了全面的文献检索,OvidEmbase,科克伦图书馆检索的研究根据预定义的纳入/排除标准筛选合格性。提取体重指数(BMI)正常和体重不足的女性的GDM患病率,平均患病率是在全球范围内计算的,世界卫生组织区域,和国家。在可用时描述妊娠结局。
    共纳入145项研究。非超重女性(BMI<25kg/m2)的GDM全球平均患病率为7.3%,体重不足女性(BMI<18.5kg/m2)为5.0%。非超重女性的GDM患病率在亚洲最高(平均12.1%),在非洲地区最低(0.7%)。患病率最高的国家是越南(21.1%),芬兰(19.8%),波兰(19.3%),孟加拉国(18.65%),和中国(17.7%)。非超重GDM女性出生的大胎龄婴儿(LGA)的全球平均患病率为9.9%,低于GDM普通人群的平均患病率(14%)。
    GDM比以前认识到的非超重女性更常见,尤其是在亚洲,但在欧洲国家也是如此。与之前报道的所有GDM女性相比,非超重GDM女性的LGA婴儿患病率较低,尽管有关妊娠结局的数据有限。这些发现挑战了建议限制GDM管理体重增加的指南。应紧急对未超重女性GDM的病理生理学和并发症进行进一步研究,以告知适当的管理指南并支持最佳的妊娠结局。
    UNASSIGNED: Gestational diabetes (GDM) affects nearly 15% of pregnancies worldwide and is increasing globally. While this growth is thought to be primarily from overweight and obesity, normal and underweight women are affected as well, particularly in low and middle-income countries. However, GDM in non-overweight women remains understudied. Thus, we examined the prevalence among normal and underweight women globally.
    UNASSIGNED: A comprehensive literature search was performed in Ovid MEDLINE, Ovid EMBASE, and The Cochrane Library. Studies retrieved were screened for eligibility against predefined inclusion/exclusion criteria. Prevalence of GDM among women with normal and underweight body mass index (BMI) was extracted, and average prevalence was calculated globally, by World Health Organization region, and by country. Pregnancy outcomes were described when available.
    UNASSIGNED: A total of 145 studies were included. The average global prevalence of GDM among non-overweight women (BMI <25 kg/m2) was 7.3% and among underweight women (BMI <18.5 kg/m2) was 5.0%. GDM prevalence in non-overweight women was highest in Asia (average 12.1%) and lowest in the African region (0.7%). The countries with the highest prevalence were Vietnam (21.1%), Finland (19.8%), Poland (19.3%), Bangladesh (18.65%), and China (17.7%). The average global prevalence of large for gestational age infants (LGA) born to non-overweight women with GDM was 9.9%, which is lower than the average prevalence in the general population with GDM (14%).
    UNASSIGNED: GDM is more common than previously recognized in non-overweight women, particularly in Asia, but also in European countries. Non-overweight women with GDM had lower prevalence of LGA babies compared to prior reported prevalence in all women with GDM, though data on pregnancy outcomes was limited. These findings challenge guidelines that recommend restriction of weight gain for GDM management. Further research on the pathophysiology and complications of GDM in women who are not overweight should be urgently conducted to inform appropriate management guidelines and support optimal pregnancy outcomes.
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