Plastic covers have been used to prevent environmental constraints negatively affecting sweet cherry production in Southern Chile. However, less information is available on agronomic practices and their effects on fruit quality in sweet cherry covered orchards. Thus, in this study, we evaluated the impact of fruit load regulation on cherries\' antioxidant-related parameters and the quality and condition at harvest and postharvest in sweet cherry (Prunus avium) cv. Regina that was cultivated under a plastic cover in Southern Chile. For this, four fruit load treatments were manually applied-(i) 100% fruit load (the control), (ii) 80% fruit load, (iii) 60% fruit load, and (iv) 40% fruit load-in a commercial sweet cherry orchard for two seasons (2021/2022 and 2022/2023). The results revealed that the yield and fruit load were not significantly different between the treatments. Interestingly, the 60% and 40% fruit loads increased the fresh weight, fruit size, and firmness (20.3%) compared to the control (the 100% fruit load) during both seasons. Likewise, the 60% and 40% fruit load treatments exhibited the highest fruit size distribution of 30 mm, while the 100 and 80% fruit load treatments showed the highest fruit distribution with fruit sizes between 28 mm and 24 mm. The total soluble solids (TSSs) did not vary among the fruit load treatments, while a significant increase was found in the titratable acidity (TA) in the 60 and 40% fruit load treatments during both seasons. No significant differences in antioxidant activity (AA) and total phenols (TPHs) among the treatments were observed during both seasons. Overall, the results revealed that the fruit load treatments, mainly 40%, increased the fruit weight and firmness and reduced pitting in fruits by 39.4% at postharvest. Thus, fruit thinning might be an important agronomical practice to regulate fruit load, positively affecting fruit quality at harvest and during postharvest storage in sweet cherry cv. Regina cultivated under a plastic cover. However, more biochemical and molecular studies are needed to elucidate the mechanism involved in this improvement.

The pitting qualities of lymphoedema tissue change with disease progression. However, little is known about the underlying tissue response to the pitting test or the tissue characteristics that enhance or resist indentation. The pitting test is currently unstandardised, and the influence of test technique on pitting outcomes is unknown. Understanding how tissue reacts to applied pressure will build evidence for the standardisation of the pitting test. Ninety pitting test sites from fifteen women with unilateral breast cancer-related lymphoedema were evaluated using high-frequency ultrasound (HFUS), bioelectrical impedance spectroscopy (BIS), and limb volume measures. Three sites on each lymphoedema and non-lymphoedema arm were subject to a 60-s (s) staged pitting test, with changes in tissue features captured with ultrasound imaging before, throughout, and after the pitting test. Pitting qualities of tissues varied greatly, with lymphoedema sites pitting more frequently (p < 0.001) with greater depth (p < 0.001) and requiring a longer recovery time (p = 0.002) than contralateral unaffected tissue. Pitting is not solely attributable to oedema volume. Non-structural and structural characteristics of dermal and subcutaneous layers also influence tissue responses to sustained pressure. To enhance the validity and reliability of pitting assessment, a 60 s staged pitting test with an observation of tissue recovery is recommended for lymphoedema presentations.

BACKGROUND: Previous studies identified corrosion between the modular tibial components of total knee arthroplasty devices. However, gaps persist. Compared to the hip, damage modes that occur within taper junctions in the knee remain poorly understood. In this study, we investigated corrosion on total knee arthroplasty components with titanium-titanium junctions. We asked the following question: under typical in vivo cyclic loading conditions, will the same alloy damage modes from total knee arthroplasty devices resemble those documented in the hip?
METHODS: A total of 50 paired titanium alloy tibial baseplates and stems were collected and semiquantitatively analyzed using Goldberg corrosion scoring. To characterize damage, a subsection of moderately and severely corroded components was sectioned and imaged using scanning electron and digital optical microscopy.
RESULTS: Of the 100 device components, 95% showed visual evidence of corrosion. The initial contact area between the stem and bore generally occurred 3 mm from the stem taper base. Scanning electron microscopy revealed 4 damage modes, including oxide film formation, crevice corrosion, selective dissolution, and pitting.
CONCLUSIONS: Each of the damage modes identified in modular titanium-titanium tibial junctions was previously reported by total hip arthroplasty retrieval studies. Cumulatively, our results suggest that mechanically assisted crevice corrosion promoted this damage in vivo.

Today, there are many diagnostic methods and advanced measurement techniques enabling the correct diagnosis and assessment of the type and degree of wear of cogwheels (gears, pumps, etc.). The present study presents an analysis of the surface defects of a cogwheel of an oil pump prototype (3PW-BPF-24). The test object operated for a certain number of hours under controlled operating and environmental parameters. The damage to the surface layer was caused by fatigue phenomena and previous thermo-chemical treatment. On the basis of the significant percentage share (~30%) of residual austenite in the volume of the diffusion layer, a hypothetical conclusion was drawn about the suboptimal parameters of the thermo-chemical treatment process (in relation to the chemical composition of the analyzed pinion). A large number of research studies indicate that the significant presence of residual austenite causes a decrease in tooth surface hardness, the initiation of brittle cracks, a sharp decrease in fatigue strength, an increase in brittleness and a tendency to develop surface layer cracks during operation. High-resolution 3D scans of randomly selected pitting defects were used in the detailed study of the present work. It was indicated that the analysis of the morphology of surface defects allowed some degree of verification of the quality of the heat/chemical treatment. The martensitic transformation of residual austenite under controlled (optimum) repeated heat treatment conditions could significantly improve the durability of the pinion (cogwheel). In the case analyzed, the preferred treatment was the low-temperature treatment. The paper concludes with detailed conclusions based on the microscopic and macroscopic investigations carried out.

Background: Alopecia areata (AA) is a common form of non-scarring alopecia characterized by acute hair loss. Nail involvement, though not always present, can occur in AA patients. Nail changes are more frequent in severe forms of AA and in children. Methods: Literature related to nail changes in AA was comprehensively reviewed after a search on the PubMed database without time restrictions in order to identify common clinical presentations and associated factors to aid clinicians with the correct evaluation and management of these dystrophies. Results: Nail changes in AA include pitting, trachyonychia, leukonychia, red lunula, and miscellaneous alterations such as longitudinal ridging and brittle nails. Nail changes are usually asymptomatic but, nevertheless, sometimes cosmetically disfiguring and can be associated with a reduced quality of life and impaired daily activities. Conclusions: Nail changes in AA may precede or follow hair loss and can occur as an isolated finding. Diagnosis may require a biopsy for definitive identification. Spontaneous improvement is possible, particularly in children, and treatment is not always necessary. Further research is, however, needed to establish a consensus on treatment approaches according to age and severity.

Objective: Lower extremity edema is characteristic of C3 chronic venous disease. We developed a new clinical and duplex ultrasound (DUS) methodology for the detection and quantification of leg edema and prospectively evaluated its usefulness. Methods: Forty-seven venous patients (94 legs) were evaluated for ankle edema using an Edema RulerTM and DUS using a modified Suehiro grading scale. Results: Interobserver reliability for the use of the Edema RulerTM was 0.985 (p < .001) and 0.883 (p < .001) for the Modified Suehiro Grade. The Edema RulerTM had stronger significant correlations with Edema rVCSS (0.842; p < .001) compared to DUS: (0.474;p < .001) with Edema rVCSS. There were significant differences between the edema pitting depth in CEAP classification of C1 and C2 compared to C3, C4a, and C4c. DUS analysis only had significant differences between CEAP classification C2 and C4a. Conclusions: The Edema RulerTM provides a quantitative measurement of lower extremity edema with high reliability which can be easily integrated into clinical practice. While both methods had good inter-observer reliability, the Edema RulerTM had stronger correlations to Edema rVCSS and showed significant differences in pitting depths between lower CEAP scores (C1-2) compared to higher CEAP scores (C3-4c).

The present work evaluates the effect of Co content on the microstructure and corrosion performance of Al-Co alloys of various compositions (2-32 wt% Co), fabricated by flux-assisted stir casting. A preliminary investigation on the effect of heat treatment (600 °C, up to 72 h) on the microstructure and corrosion behavior of Al-20 wt% Co and Al-32 wt% Co was also conducted. The Al- (2-10) wt% Co alloys were composed of acicular Al9Co2 particles uniformly dispersed in an Al matrix. The Al-20 wt% Co and Al-32 wt% Co alloys additionally contained Al13Co4 blades enveloped in Al9Co2 wedges. Heat treatment of Al-20 wt% Co and Al-32 wt% Co led to a significant reduction in the volume fraction of Al13Co4 and a decrease in hardness. Al-Co alloys with high Co content (10-32 wt% Co) exhibited greater resistance to localized corrosion in 3.5 wt% NaCl, but lower resistance to general corrosion compared to the (0-5 wt% Co) alloys. Heat treatment led to a slight increase in the corrosion resistance of the Al-Co alloys. The microstructure of the produced alloys was analyzed and correlated with the corrosion performance. Finally, corrosion mechanisms were formulated.

Lower extremity edema is a symptom of chronic venous disease and venous insufficiency. However, clinical evaluations rely on the qualitative evaluation of the pitting depth, which is neither well-defined nor quantitative. We created a novel three-dimensionally printed edema ruler as a quantitative method to measure pitting depth. Twenty-five patients (50 legs) with chronic venous disease were evaluated for ankle edema using the edema ruler. The results demonstrate excellent intraclass correlation for both single (0.944, P < .001) and average (0.971, P < .001) measurements. The edema ruler is a noninvasive, useful, and objective tool for the clinical measurement of lower extremity edema.

BACKGROUND: The prevalence and clinical characteristics of different etiologies of peripheral edema in dogs are unknown.
OBJECTIVE: To determine the prevalence of different etiologies of peripheral edema, describe clinical characteristics that vary among etiologies, and report survival times.
METHODS: Five hundred twenty-seven dogs with peripheral edema.
METHODS: Retrospective medical record review. Differences in clinical variables among etiology groups were assessed by Kruskal-Wallis testing with post hoc pairwise Dunn\'s testing and Chi-square testing with Monte Carlo simulation.
RESULTS: The most common etiologies of peripheral edema in dogs were vasculitis (n = 193, 37%), lymphatic/venous obstruction (LVO; 114, 22%), and hypoalbuminemia (94, 18%). Right-sided congestive heart failure (R-CHF) was uncommon (25, 5%). Edema was localized in 377 (72%) dogs and generalized in 142 (27%) dogs, and hypoalbuminemia was more likely to cause generalized edema compared to LVO or vasculitis (P < .0001). Concurrent abdominal effusion (155, 29%) was more common than pleural (77, 15%) or pericardial (12, 2%) effusion. Abdominal and pleural effusion occurred more commonly in dogs with hypoalbuminemia or R-CHF compared to LVO or vasculitis (P < .0001).
CONCLUSIONS: Distribution of edema, concurrent cavitary effusions, and clinicopathological data can help predict the underlying etiology of peripheral edema in dogs.

The hydrocarbon industry constantly requires a better understanding of stainless-steel welding metallurgy. Despite the fact that gas metal arc welding (GMAW) is one of the most commonly employed welding processes in the petrochemical industry, the process is characterized by the presence of a high number of variables to control in order to obtain components that are dimensionally repeatable and satisfy the functional requirements. In particular, corrosion is still a phenomenon that highly affects the performance of the exposed materials, and special attention must be paid when welding is applied. In this study, the real operating conditions of petrochemical industry were reproduced through an accelerated test in a corrosion reactor at 70 °C for 600 h, exposing robotic GMAW samples free of defects with suitable geometry. The results show that, even if duplex stainless steels are characterized for being more corrosion resistant than other stainless steels, under these conditions it was possible to identify microstructural damage. In detail was found that the corrosion properties were strongly related to the heat input during welding and that the best corrosion properties can be obtained with the higher heat input.