Abstract：
Objective: Lower extremity edema is characteristic of C3 chronic venous disease. We developed a new clinical and duplex ultrasound (DUS) methodology for the detection and quantification of leg edema and prospectively evaluated its usefulness. Methods: Forty-seven venous patients (94 legs) were evaluated for ankle edema using an Edema RulerTM and DUS using a modified Suehiro grading scale. Results: Interobserver reliability for the use of the Edema RulerTM was 0.985 (p < .001) and 0.883 (p < .001) for the Modified Suehiro Grade. The Edema RulerTM had stronger significant correlations with Edema rVCSS (0.842; p < .001) compared to DUS: (0.474;p < .001) with Edema rVCSS. There were significant differences between the edema pitting depth in CEAP classification of C1 and C2 compared to C3, C4a, and C4c. DUS analysis only had significant differences between CEAP classification C2 and C4a. Conclusions: The Edema RulerTM provides a quantitative measurement of lower extremity edema with high reliability which can be easily integrated into clinical practice. While both methods had good inter-observer reliability, the Edema RulerTM had stronger correlations to Edema rVCSS and showed significant differences in pitting depths between lower CEAP scores (C1-2) compared to higher CEAP scores (C3-4c).
摘要：
目的：下肢水肿是C3慢性静脉疾病的特征性表现。我们开发了一种新的临床和双工超声（DUS）方法，用于检测和定量腿部水肿，并前瞻性评估了其有效性。方法：使用改良的Suehiro分级量表，使用EdemaRulerTM和DUS评估了47例静脉患者（94条腿）的踝关节水肿。结果：对于改良的Suehiro等级，使用EdemaRulerTM的观察者间可靠性为0.985（p<.001）和0.883（p<.001）。与具有EdemarVCSS的DUS：（0.474；p<.001）相比，EdemaRulerTM与EdemarVCSS（0.842；p<.001）具有更强的显着相关性。CEAP分级C1和C2的水肿点蚀深度与C3、C4a相比有显著差异,C4cDUS分析仅在CEAP分类C2和C4a之间有显著差异。结论：EdmaRulerTM提供了一种高可靠性的下肢水肿定量测量方法，可以很容易地融入临床实践。虽然这两种方法都有很好的观察者间可靠性，EdemaRulerTM与EdemarVCSS有更强的相关性,与较高的CEAP评分(C3-4c)相比,较低的CEAP评分(C1-2)在凹陷深度上有显著差异.
