Nutritional Requirements

营养要求
  • 文章类型: Journal Article
    Prader-Willi综合征(PWS)是一种罕见的疾病,其特征是在整个生命周期中发生不同的营养阶段,从失败到茁壮成长到饮食过度。如果不受控制,能量摄入和消耗之间的不平衡导致肥胖的发展以及发病率和死亡率的增加.尽管准确的营养评估所需能量的措施至关重要,证据显得稀疏和异质;因此,这篇综述的目的是研究可用的文献,在PWS患者中使用各种方法预测或测量能量消耗。寻求提供有关静息能量消耗或基础代谢率的方法和结果的研究。完成了叙述性综合,以介绍研究特征和结果。确定能量需求的方法包括预测方程和间接量热法。年龄之间的差异,生长激素治疗,空腹状态,以及提出结果的措施限制了适当总结和确定能源支出趋势。间接量热法被认为是最准确的方法;然而,它并非在所有设置中广泛可用。鼓励进一步的研究,以支持有效和可靠的预测方程的发展,这将更好地告知和提高临床实践的效率,支持PWS的人。
    Prader-Willi syndrome (PWS) is a rare disorder characterised by varying nutritional phases that occur throughout the lifespan, ranging from failure to thrive to hyperphagia. If uncontrolled, the imbalance between energy intake and expenditure results in obesity development and increased morbidity and mortality risk. Although measures of energy requirements for accurate nutrition assessment are vital, the evidence appears sparse and heterogeneous; hence, the aim of this review was to examine the available literature on energy expenditure predicted or measured using various methods in individuals with PWS. Studies were sought that presented methods and results on resting energy expenditure or basal metabolic rate. A narrative synthesis was completed to present the study characteristics and results. Methods of determining energy requirements included predictive equations and indirect calorimetry. Differences amongst ages, growth hormone therapy, fasting status, and measures in which results were presented were limitations to appropriately summarising and identifying trends in energy expenditure. Indirect calorimetry was identified as the most accurate method; however, it is not widely available in all settings. Further research is encouraged to support the development of valid and reliable predictive equations that will better inform and improve the efficiency of clinical practice in supporting people with PWS.
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  • 文章类型: Journal Article
    美式足球运动员遵循传统建议消耗大量动物来源的蛋白质,以最大限度地提高肌肉发育和运动表现。这与饮食指南相反,建议减少肉类摄入量和增加植物性食物的消费,以促进健康和降低慢性病的风险。尚未研究完全基于植物的饮食满足美式足球运动员营养需求的能力。这项建模研究将饮食数据从一个大的队列中进行缩放,这些数据遵循完全基于植物的饮食,以满足职业美式足球运动员的能量需求,以确定蛋白质是否,亮氨酸,和微量营养素需求的身体表现和健康得到满足。坎宁安方程用于估计卡路里需求。然后将来自复临安息日会健康研究2的营养素摄入量缩放到该卡路里水平。蛋白质值范围为1.6-2.2克/千克/天,亮氨酸值范围为3.8-4.1克/餐,每天四餐,因此,达到并超过理论上最大化肌肉质量的水平,肌肉力量,和肌肉蛋白质合成,分别。以植物为基础的饮食规模,以满足职业美式足球运动员的能源需求满足蛋白质,亮氨酸,以及肌肉发育和运动表现所需的微量营养素。这些发现表明,完全基于植物的饮食可以弥合美式足球运动员预防慢性病的饮食建议与运动表现之间的差距。
    American football players consume large quantities of animal-sourced protein in adherence with traditional recommendations to maximize muscle development and athletic performance. This contrasts with dietary guidelines, which recommend reducing meat intake and increasing consumption of plant-based foods to promote health and reduce the risk of chronic disease. The capacity of completely plant-based diets to meet the nutritional needs of American football players has not been studied. This modeling study scaled dietary data from a large cohort following completely plant-based diets to meet the energy requirements of professional American football players to determine whether protein, leucine, and micronutrient needs for physical performance and health were met. The Cunningham equation was used to estimate calorie requirements. Nutrient intakes from the Adventist Health Study 2 were then scaled to this calorie level. Protein values ranged from 1.6-2.2 g/kg/day and leucine values ranged from 3.8-4.1 g/meal at each of four daily meals, therefore meeting and exceeding levels theorized to maximize muscle mass, muscle strength, and muscle protein synthesis, respectively. Plant-based diets scaled to meet the energy needs of professional American football players satisfied protein, leucine, and micronutrient requirements for muscle development and athletic performance. These findings suggest that completely plant-based diets could bridge the gap between dietary recommendations for chronic disease prevention and athletic performance in American football players.
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  • 文章类型: Journal Article
    背景:肺运动康复的有限益处与满足能量和蛋白质需求有关。
    目的:目的是提高膳食摄入量,以满足肺康复计划后的需求并保持变化。
    方法:这项单臂干预研究包括对营养的多学科关注和在五个城市中心进行为期10周的肺运动康复期间进行的三次个人饮食咨询。数据在基线(P0)收集,在干预结束时(P1)和两个城市在干预后三个月(P2)。
    结果:在111名参与者中,(平均年龄70.8(±9))99(89%)完成了康复,包括三个单独的饮食咨询。发现包括体重指数和运动能力在内的身体成分差异很大。蛋白质摄入量从64(±22g)(P0)提高到88(±25g)(P1)(p<0.001),能量摄入量从1676(±505kcal)(P0)提高到1941(±553kcal)(p<0.001)(P1),肌肉质量指数从10.6(±3.2)(P0)提高到10.9(±3.2)(P1)(p=1)的重复次数(六分钟步行试验中的距离从377.2(±131.2m)(P0)提高到404.1(±128.6m)(P1)(p<0.001)。两个城市完成了为期三个月的后续行动。对于那些,饮食改善保持稳定,包括蛋白质的摄入。
    结论:在多专业的努力中包括三次饮食咨询与改善个性化饮食摄入有关,以及身体功能。三个月后,福利几乎保持不变。功能的改进不能完全用改进的摄入量来解释。
    BACKGROUND: Limited benefit of pulmonary exercise rehabilitation has been associated with fulfilment of energy and protein requirements.
    OBJECTIVE: The aim was to enhance dietary intake towards requirements and to maintain changes after a pulmonary rehabilitation program.
    METHODS: This single arm intervention study included multidisciplinary focus on nutrition and three sessions of individual dietary counselling during a 10-week pulmonary exercise rehabilitation in five municipalities centers. Data were collected at baseline (P0), at the end of intervention (P1) and for two municipalities at three months post intervention (P2).
    RESULTS: Of the 111 included participants, (mean age 70.8 (±9)) 99 (89%) completed the rehabilitation including the three individual dietary counselling\'s. A very large variation in body composition including body mass index and exercise abilities was found. Protein intake improved from 64 (±22 g) (P0) to 88 (±25 g) (P1) (p < 0.001) and energy intake from 1676 (±505 kcal) (P0) to 1941 (±553 kcal) (p < 0.001) (P1) and Muscle Mass Index increased from 10.6 (±3.2) (P0) to 10.9 (±3.2) (P1) (p = 0.007); number of 30 s chair stand test improved from 10.9 (±2.8) repetitions (P0) to 14.1 (±4.3) repetitions (P1) (p < 0.001), distance in six-minut walking test improved from 377.2 (±131.2 m) (P0) to 404.1 (±128.6 m) (P1) (p < 0.001). Two municipalities completed the three months follow-up. For those, dietary improvements remained stable, including protein intake.
    CONCLUSIONS: Including three sessions of dietary counselling in a multi-professional effort was associated with improved individualized dietary intake, as well as physical function. Benefits remained almost unchanged after three months. Improvements in function could not be fully explained by improved intakes.
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  • 文章类型: Journal Article
    牛肉是优质蛋白质和多种微量营养素的重要来源,包括铁,锌,B族维生素。我们使用5868名老年人的24小时饮食回忆数据确定了牛肉摄入量及其与营养素摄入量及其充足性的关系。通常的食物摄入量是使用国家癌症研究所的方法确定的,并估计了低于估计平均需求或高于足够摄入量的人口百分比。高比例的老年人不符合维生素D的营养建议(96%),胆碱(96%),维生素E(84%),钾(70%),钙(63%),镁(60%),维生素C(46%),维生素A(39%),锌(21%),维生素B6(19%),和叶酸(15%)。大约68%的老年人是牛肉消费者,平均摄入量为56克/天。牛肉消费者的能量摄入量较高(p<0.05),蛋白质,钙,铁,磷,硒,钠,锌,硫胺素,核黄素,烟酸,维生素B12和胆碱,和更高的(P<0.05)比例满足蛋白质的营养建议,钙,铜,锌,硫胺素,叶酸,和维生素B12比非消费者。消费者的新鲜,地面,根据牛肉的类型,加工牛肉的摄入量通常较高,许多营养素的不足较低。总之,老年人通常从他们的饮食中营养充足性差,虽然牛肉消费者的营养摄入量较高,某些关键营养素充足,通常可以从牛肉或与牛肉一起食用的食物中获得。
    Beef is an important source of high-quality protein and several micronutrients, including iron, zinc, and B vitamins. We determined beef intake and its relationship with intakes of nutrients and their adequacy using 24 h dietary recall data from 5868 older adults. Usual intakes from foods were determined using the National Cancer Institute method, and the percent of the population below the estimated average requirement or above adequate intake was estimated. A high percentage of older adults did not meet nutrient recommendations for vitamin D (96%), choline (96%), vitamin E (84%), potassium (70%), calcium (63%), magnesium (60%), vitamin C (46%), vitamin A (39%), zinc (21%), vitamin B6 (19%), and folate (15%). About 68% of older adults were beef consumers with a mean intake of 56 g/day. Beef consumers had higher (p < 0.05) intakes of energy, protein, calcium, iron, phosphorus, selenium, sodium, zinc, thiamin, riboflavin, niacin, vitamin B12, and choline, and a higher (p < 0.05) proportion met nutrient recommendations for protein, calcium, copper, zinc, thiamin, folate, and vitamin B12 than non-consumers. Consumers of fresh, ground, and processed beef also had generally higher intakes and lower inadequacies of many nutrients depending on the beef type. In conclusion, older adults generally had poor nutrient adequacy from their diets, while beef consumers had higher nutrient intakes and adequacy for certain key nutrients, which are inherently generally available from beef or from foods consumed with beef.
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  • 文章类型: Systematic Review
    了解糖的摄入量与饮食质量之间的关系可以为公共卫生建议提供信息。本系统综述综合了有关2岁或2岁以上的一般健康人群中糖摄入量与饮食质量之间关联的最新文献。我们在2010年至2022年的数据库中搜索了任何设计的研究,这些设计检查了日常饮食中定量糖摄入量与饮食指数(DI)或微量营养素摄入量之间的关联。对不同的糖类型和饮食质量指标进行了分析。我们将DI结果转换为Pearson的r相关性,并对有或没有游离或添加糖成分的指数进行分组,以促进交叉研究比较。Meta分析被认为是不恰当的。从13869条筛选记录中,我们纳入了27项横断面研究.NUQUEST偏倚风险评级为中性(n=18项研究)或较差(n=9),由于研究设计,GRADE方法的证据强度非常低。大多数研究报告了添加和游离糖与饮食质量指标(r范围从-0.13到-0.42)和公共卫生关注的营养素(纤维,维生素D,钙,钾),而与总糖的关联是混合的。由于横断面研究设计,这些发现的临床相关性尚不清楚.需要进行前瞻性研究以最大程度地减少混淆并告知因果关系。
    Understanding the relationship between the intake of sugars and diet quality can inform public health recommendations. This systematic review synthesized recent literature on associations between sugar intake and diet quality in generally healthy populations aged 2 years or older. We searched databases from 2010 to 2022 for studies of any design examining associations between quantified sugar intake in the daily diet and dietary indexes (DIs) or micronutrient intakes. Different sugar types and diet quality measures were analyzed separately. We converted DI results to Pearson\'s r correlations and grouped indexes with or without a free or added sugar component to facilitate cross-study comparisons. Meta-analysis was deemed inappropriate. From 13,869 screened records, we included 27 cross-sectional studies. NUQUEST risk of bias ratings were neutral (n = 18 studies) or poor (n = 9), and strength of evidence by the GRADE approach was very low due to study design. Most studies reported negative associations for added and free sugars with diet quality indexes (r ranging from -0.13 to -0.42) and nutrients of public health concern (fiber, vitamin D, calcium, potassium), while associations with total sugars were mixed. Due to cross-sectional study designs, the clinical relevance of these findings is unclear. Prospective studies are needed to minimize confounding and inform causal relationships.
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  • 文章类型: Journal Article
    微量营养素在人类健康中起着关键作用,参与能量代谢,豁免权,细胞功能,增长,和发展。由于多种因素,所有年龄段的个体都会出现微量营养素的缺乏,包括饮食不足,疾病状态,和超重/肥胖。印度医学研究理事会(ICMR)国家营养研究所(NIN)印度人营养需求专家组(2023年)的指南规定了大量营养素和微量营养素的推荐膳食配额(RDA)。此外,健康的饮食对整体健康至关重要,应该是解决微量营养素缺乏的第一步。当饮食不足时,可以提供微量营养素补充剂来补偿。召集了印度医生专家小组,以制定在印度人口中补充微量营养素的途径。本共识声明承认,不同人群对特定微量营养素的需求各不相同,并确保这些微量营养素的充足摄入可以改善健康结果。小组为饮食不足时的饮食习惯和微量营养素补充提供了建议。在初级保健一级解决微量营养素缺乏症可以预防慢性缺乏症及其后果。这份共识声明可以作为医生监测和解决缺陷的入门书,从而帮助个人保持健康。
    Micronutrients play a key role in human health, being involved in energy metabolism, immunity, cellular functioning, growth, and development. Deficiencies in micronutrients occur in individuals of all ages due to several factors, including inadequate diets, disease states, and overweight/obesity. Guidelines from the Indian Council of Medical Research (ICMR) National Institute of Nutrition (NIN) Expert Group on Nutrient Requirements for Indians (2023) have specified the Recommended Dietary Allowances (RDA) for macronutrients and micronutrients. In addition, a healthy diet is crucial for overall health and should be the first step toward addressing micronutrient deficiencies. When diet is inadequate, micronutrient supplements can be provided to compensate. An expert panel of Indian doctors was convened to develop a pathway toward micronutrient supplementation among the Indian population. This Consensus Statement recognizes that different populations have varying needs for specific micronutrients, and ensuring adequate intake of such micronutrients can improve health outcomes. The panel provided recommendations for dietary practices and micronutrient supplementation when diet is inadequate. Addressing micronutrient deficiencies at the primary care level can prevent chronic deficiencies and their consequences. This Consensus Statement can serve as a primer for physicians to monitor and address deficiencies and thus help individuals maintain their health.
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  • 文章类型: Journal Article
    微量营养素(MN),即微量元素和维生素,是必需的有机分子,在饮食中需要相对少量的任何形式的营养(口服,肠内,肠胃外)。在所有慢性疾病中,应考虑MN耗尽或缺乏的可能性,尤其是那些会干扰摄入的,消化,或肠道吸收。低社会经济地位和食物匮乏被认为是全球MN缺乏的最普遍原因。多模式治疗的老年患者,以及有长期菜单限制的患者,与疾病相关的营养不良以及多种MN缺陷的高风险,需要仔细的具体跟进。监测MN血液水平以及CRP的重要性对于最佳护理至关重要。药物相互作用也被强调。在依赖医学营养治疗的慢性病患者中,提供足够的MN剂量的饮食参考摄入量(DRI)并监测其充足性属于护理标准.
    Micronutrients (MN), i.e. trace elements and vitamins, are essential organic molecules, which are required in the diet in relatively small amounts in any form of nutrition (oral, enteral, parenteral). The probability of MN depletion or deficiencies should be considered in all chronic illnesses, especially in those that can interfere with intake, digestion, or intestinal absorption. Low socio-economic status and food deprivation are recognized as the most prevalent reasons for MN deficiencies world-wide. Elderly multimorbid patients with multimodal therapy, as well as patients with long-lasting menu restrictions, are at high risk for both disease related malnutrition as well as multiple MN deficiencies, needing careful specific follow-up. The importance of monitoring MN blood levels along with CRP is essential for optimal care. Drug interactions are also highlighted. In patients with chronic conditions depending on medical nutrition therapy, the provision of adequate dietary reference intakes (DRI) of MN doses and monitoring of their adequacy belongs to standard of care.
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  • 文章类型: Journal Article
    运动营养是运动表现的重要组成部分。本研究的目的是调查美国大学体育协会大学运动员的运动营养知识,并评估自我报告的对能量和大量营养素摄入的感知需求。次要目的是评估与正念饮食相关的身体和情感感知的意识。
    参与者包括NCAAI部(DI,n=45),II(DII,n=31),和III(DIII,n=47)运动员。运动员完成了旨在评估运动营养知识的经过验证的问卷,并被问及有关其感知的饮食能量和大量营养素需求的问题。每日能量摄入值使用40、50和60kcal/kg/天的推荐相对能量摄入值计算,中度,和高活动水平,分别。使用4、6和8g/kg/天计算碳水化合物建议,蛋白质推荐使用1.4、1.6和1.8g/kg/天的相对摄入量计算,和脂肪建议是根据预测的每日总能量需求的相对百分比计算的,相当于每日能量的15%、25%和30%。此外,运动员填写了一份问卷,以评估有关饮食习惯的正念。
    总的来说,运动员在营养问卷中正确回答了45.5±13.5%的问题,男性运动员(48.6±13.6%)和女性运动员(43.6±13.2%;p=0.044)之间存在显着差异,以及在DI运动员得分(38.8±14.1%)和DII运动员(47.7±11.4%;p=0.002)之间观察到的显着差异,DI运动员和DIII运动员(51.71±11.83%;p=<0.001)。所有运动员都显著(p<0.001)低估了每日能量摄入需求(女性,2,112±575千卡/天;男性,3,283±538千卡/天)。男性运动员(65.1±6.5)的正念饮食习惯总分明显高于女性运动员(60.9±9.5;p=0.009)。
    第一部分,II,和III大学运动员的运动营养知识较差,在运动营养知识问卷中,与II级和III级运动员相比,I级运动员的得分较低。来自各级大学运动的运动员低估了他们的能量和大量营养素需求。女性和男性运动员在注意饮食习惯方面的差异也很明显。
    UNASSIGNED: Sports nutrition is an impactful component to sports performance. The purpose of the current study was to investigate the sports nutrition knowledge of National Collegiate Athletic Association collegiate athletes and assess self-reported perceived requirements for energy and macronutrient intake. A secondary aim was to evaluate the awareness of physical and emotional perceptions associated with mindful eating.
    UNASSIGNED: Participants included NCAA Division I (DI, n = 45), II (DII, n = 31), and III (DIII, n = 47) athletes. Athletes completed a validated questionnaire designed to assess sports nutrition knowledge and were asked questions about their perceived dietary energy and macronutrient requirements. Daily energy intake values were calculated using a recommended relative energy intake value of 40, 50, and 60 kcal/kg/day for low, moderate, and high activity levels, respectively. Carbohydrate recommendations were calculated using 4, 6, and 8 g/kg/day, protein recommendations were calculated using relative intakes of 1.4, 1.6, and 1.8 g/kg/day, and fat recommendations were calculated from a relative percentage of total predicted daily energy requirements, equating to 15, 25, and 30% of daily energy. Additionally, athletes completed a questionnaire to assess mindfulness regarding eating habits.
    UNASSIGNED: Overall, athletes answered 45.5 ± 13.5% of questions correctly on the nutrition questionnaire with significant differences observed between male (48.6 ± 13.6%) and female athletes (43.6 ± 13.2%; p = 0.044), as well as significant differences observed between DI athlete scores (38.8 ± 14.1%) and DII athletes (47.7 ± 11.4%; p = 0.002), and DI athletes and DIII athletes (51.71 ± 11.83%; p =  <0.001). All athletes significantly (p < 0.001) underestimated daily energy intake requirements (female, 2,112 ± 575 kcal/day; male, 3,283 ± 538 kcal/day). The mindfulness eating habits total score was significantly higher in male athletes (65.1 ± 6.5) compared to female athletes (60.9 ± 9.5; p = 0.009).
    UNASSIGNED: Division I, II, and III collegiate athletes have poor sports nutrition knowledge, with Division I athletes having exhibited lower scores compared to Division II and III athletes on the sports nutrition knowledge questionnaire. Athletes from all levels of collegiate sports underestimated their energy and macronutrient requirements. Differences in mindful eating habits among female and male athletes were also evident.
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  • 文章类型: Journal Article
    六十多年来,营养科学提供了发达的,同行评审的营养建议,以支持狗和猫的健康。这些指南是根据新的科学有效研究和适当的同行评审进行更新的。最近围绕健康问题的监管和科学立场导致了围绕矿物质营养的快速监管行动的强烈意见和愿望。但科学证据有限且相互矛盾。宠物食品研究所的营养专家聚集在一起,共同撰写了一篇关于建立狗和猫的矿物质耐受性的复杂性的文章,以说明定义矿物质耐受性的局限性。本讨论涵盖了如何确定矿物需求,包括遇到的机会和陷阱。科学委员会必须审查并澄清进行矿物质营养研究的任何拟议变化,这些变化可能会影响完整和平衡的食品和周围的法规。重要的是要澄清矿物质营养研究中的多个问题以及对数据进行彻底评估的必要性,同时避免任意和潜在有害的指南。
    狗和猫的寿命更长,更健康,在某种程度上,营养信息的科学发展。这些信息使许多新型食品的建立,对待,和促进生命的补充剂,健康,和宠物的享受。有几个组织通过科学委员会提供了对营养数据的有用审查,帮助确定所有宠物食品的安全和健康标准。对于那些想要了解更多关于宠物营养的人来说,这些都是现成的。对于许多营养素来说,有一个大型的信息数据库来帮助构建产品。称为宏观或微观/痕量矿物质的营养素(例如,钠,钾,锌,铜,等。)通常拥有更有限的信息。最近,关于宠物健康与矿物质营养相关的强烈观点已经被分享和有力地传达,没有足够的科学研究来支持这些假设。这导致了错误信息,关注,和恐惧。保护伴侣动物的健康,并就狗和猫的营养福利向监管机构提供协助,科学小组来自工业界,政府,和学术界来审查,批准,挑战营养指南。本概述为读者提供了建立狗和猫的安全矿物质耐受性所需的严谨性。
    For over six decades, nutritional science has provided well-developed, peer-reviewed nutrient recommendations to support the health of dogs and cats. These guidelines are updated based on new scientifically valid research and appropriate peer-review. Recent regulatory and scientific positions around health issues have resulted in strong opinions and desires for rapid regulatory action surrounding mineral nutrition, but with limited and conflicting scientific evidence. Pet Food Institute nutrition experts have come together to jointly author an article on the complexities of establishing mineral tolerances of dogs and cats to illustrate the limitations in defining mineral tolerances. This discussion covers how mineral requirements were determined, including the opportunities and pitfalls encountered. Scientific councils must review and clarify any proposed changes in conducting mineral nutrition research that might impact complete and balanced foods and surrounding regulations. It is important to clarify the multiple issues in mineral nutrition research and the necessity for thorough evaluation of data while avoiding arbitrary and potentially harmful guidelines.
    Dogs and cats are living longer and healthier lives due, in part, to the scientific development of nutritional information. This information has allowed the building of many new types of foods, treats, and supplements that promote life, health, and enjoyment by the pet. There are several organizations that have provided helpful reviews of nutritional data through scientific councils that help identify safe and healthy criteria for all pet food products. These are readily available for those who want to learn more about pet nutrition. For many nutrients, there is a large database of information to help build products. Nutrients that are called macro- or micro-/trace minerals (e.g., sodium, potassium, zinc, copper, etc.) often have more limited information. Recently, strong opinions about pet health as related to mineral nutrition have been shared and robustly communicated without adequate scientific research to support the hypotheses. This has led to misinformation, concerns, and fear. To safeguard the health of companion animals and provide assistance to regulatory bodies regarding the nutritional welfare of dogs and cats, scientific panels have come together from industry, government, and academia to review, approve, and challenge nutritional guidelines. This overview provides the reader context into the rigor needed to establish safe mineral tolerances for dogs and cats.
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  • 文章类型: Journal Article
    微量营养素(MN),即微量元素和维生素,在任何形式的营养中都是饮食中相对少量的必需成分,危重病人的特殊需求。危重病的特征是存在炎症和氧化应激。MNs紧密参与抗氧化剂和免疫防御。此外,一些条件,和处理导致含有MNs的生物流体大量损失:因此,需要肾脏替代疗法的急性肾损伤,急性肠衰竭,严重的烧伤和创伤是身体储存急性耗尽的高风险,和缺乏。MN要求增加到标准DRI之上。血液水平解释因炎症而变得复杂:一些生物标志物有助于状态确定。由于危重疾病的严峻挑战,它的最重要的是覆盖需要维持生物体的内源性免疫和抗氧化防御,和修复组织的能力。提出了切实可行的策略。
    Micronutrients (MN), i.e. trace elements and vitamins, are essential components of the diet in relatively small amounts in any form of nutrition, with special needs in critically ill patients. Critical illness is characterised by the presence of inflammation and oxidative stress. MNs are tightly involved in antioxidant and immune defences. In addition, some conditions, and treatments result in large losses of biological fluids containing MNs: therefore, acute renal injury requiring renal replacement therapy, acute intestinal failure, and major burns and trauma are at high risk of acute depletion of body stores, and of deficiency. MN requirements are increased above standard DRI. Blood level interpretation is complicated by inflammation: some biomarkers assist the status determination. Due to the acute challenges of critical illness, it of utmost importance to cover the needs to maintain the organism\'s endogenous immune and antioxidant defences, and capacity to repair tissues. Practical strategies are proposed.
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