Mimicking

模仿
  • 文章类型: Journal Article
    现代神经影像学方法并不能完全排除颅内动脉瘤的误诊,这可能导致与并发症风险相关的不必要的手术。然而,错误诊断的动脉瘤的手术干预非常罕见。这项研究的目的是证明两个假阳性动脉瘤的临床病例,并对致力于假阳性动脉瘤的发生率和病因的文献进行系统回顾,确定与假阳性动脉瘤相关的危险因素。在两个数据库(PubMed和WebofScience)中使用关键字“模仿颅内动脉瘤”进行文献检索,“表现为颅内动脉瘤”,“颅内动脉瘤假阳性”,并进行了“神经外科手术”。在两个数据库中的初始搜索中共发现了243篇论文。最终分析包括16篇论文(包括20例患者)。有10个女人和10个男人。假阳性动脉瘤的最常见位置是大脑中动脉(MCA)的分叉。在后循环中,在基底动脉上发现了假阳性动脉瘤,或者在椎-基底交界处.颅内动脉瘤假性诊断的主要原因包括动脉闭塞伴血管残端形成,漏斗加宽,开窗术,动脉夹层,造影剂外渗,和静脉静脉曲张.总之,总结我们的分析结果,我们可以说,假阳性动脉瘤的手术干预在血管神经外科中是一个被低估的问题。尽管发表的临床观察非常罕见,对假阳性动脉瘤进行错误手术干预的实际频率未知.
    Modern neuroimaging methods do not completely rule out false diagnoses of intracranial aneurysms which can lead to an unwarranted operation associated with risks of complications. However, surgical interventions for falsely diagnosed aneurysms are quite rare. The purpose of this study is to demonstrate two clinical cases of false-positive aneurysms and a systematic review of the literature dedicated to the incidence and etiology of false-positive aneurysms, identifying risk factors associated with false-positive aneurysms. A literature search in two databases (PubMed and Web of Science) using keywords \"mimicking an intracranial aneurysm\", \"presenting as an intracranial aneurysm\", \"false positive intracranial aneurysms\", and \"neurosurgery\" was conducted. A total of 243 papers were found in the initial search in two databases. Sixteen papers (including 20 patients) were included in the final analysis. There were 10 women and 10 men. The most common location of false-positive aneurysms was the bifurcation of the middle cerebral artery (MCA). In the posterior circulation, false-positive aneurysms were identified either on the basilar artery, or at the vertebro-basilar junction. The main causes of false intracranial aneurysm diagnosis included artery occlusion with vascular stump formation, infundibular widening, fenestration, arterial dissection, contrast extravasation, and venous varix. In conclusion, summarizing the results of our analysis, we can say that surgical interventions for false-positive aneurysms are an underestimated problem in vascular neurosurgery. Despite extremely rare published clinical observations, the actual frequency of erroneous surgical interventions for false-positive aneurysms is unknown.
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  • 文章类型: Case Reports
    血吸虫病,一种寄生虫病,是由血吸虫属的血吸虫引起的。神经血吸虫病是最严重的血吸虫病,当宿主的大脑和脊髓对卵子的沉积作出反应时,导致神经症状.神经血吸虫病引起各种体征和症状,比如脊髓病,神经根病,颅内压升高.
    一名来自埃塞俄比亚的12岁儿童,下肢进行性无力,持续2个月。除了弱点,患者下肢也有刺痛感和麻木。此外,他有膀胱和肠失禁。脊柱MRI显示有粘液乳头状室管膜瘤的征象,但组织病理学结果显示血吸虫病。术后,患者的下肢无力(手指闪烁)略有改善。然而,他的节制能力没有改善。
    曼氏血吸虫感染最常见的神经系统表现是脊髓病,其中包括亚急性脊髓病和急性横贯性脊髓炎。马尾和延髓圆锥是最常受影响的区域。
    当脊柱血吸虫病表现为模仿脊柱肿瘤时,它提出了一个复杂的临床挑战,需要一个全面的跨学科方法,以确保准确的诊断和有效的治疗。这是当务之急的保健医生,以提高他们的知识和这种罕见的寄生虫感染的认识,特别是在流行的地区。
    UNASSIGNED: Schistosomiasis, a parasitic disease, is caused by blood flukes from the schistosoma genus. Neuroschistosomiasis is the most severe form of schistosomiasis, which occurs when the host\'s brain and spinal cord react to the deposition of eggs, leading to neurological symptoms. Neuroschistosomiasis causes various signs and symptoms, such as myelopathy, radiculopathy, and elevated intracranial pressure.
    UNASSIGNED: A 12-year-old child from Ethiopia who presented with progressive weakness in his lower extremities that has been ongoing for 2 months. Alongside the weakness, the patient also experienced tingling sensations and numbness in his lower extremities. Additionally, he had bladder and bowel incontinence. Spinal MRI showed signs suggestive of myxopapillary ependymoma, but the histopathology result showed schistosomiasis. Postoperatively, the patient had a slight improvement in terms of lower extremity weakness (flickering of the digits). However, there was no improvement in his continence ability.
    UNASSIGNED: The most common neurological manifestation of Schistosoma mansoni infection is myelopathy, which includes subacute myeloradiculopathy and acute transverse myelitis. The cauda equina and conus medullaris are the areas most frequently affected.
    UNASSIGNED: When spinal schistosomiasis presents itself as a mimicking spinal tumour, it poses a complex clinical challenge that necessitates a comprehensive interdisciplinary approach to ensure accurate diagnosis and effective treatment. It is imperative for healthcare practitioners to enhance their knowledge and awareness of this uncommon parasitic infection, particularly in regions where it is prevalent.
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  • 文章类型: Case Reports
    毛细血管瘤,通常在皮肤和粘膜组织中发现,很少在脊髓内遇到,提出了重大的诊断挑战。我们报告了一名66岁女性患者的脊髓圆锥硬膜内髓外毛细血管瘤的罕见病例。由于存在囊性形成和壁结节增强,因此根据MRI发现,我们的初步诊断倾向于囊性血管母细胞瘤。然而,手术探查和随后的病理检查显示病变为毛细血管血管瘤。就作者所知,该病例可能是首次有文献记载的脊髓毛细血管瘤,其模拟囊性血管母细胞瘤。
    Capillary hemangiomas, usually found in skin and mucosal tissues, are rarely encountered within the spinal cord, presenting a significant diagnostic challenge. We report a rare case of intradural extramedullary capillary hemangioma at the conus medullaris in a 66-year-old female patient. Our initial diagnosis leaned towards a cystic hemangioblastoma based on MRI findings due to the presence of cystic formation with an enhanced mural nodule. However, surgical exploration and subsequent pathological examination revealed the lesion as a capillary hemangioma. To the authors\' knowledge, this case may represent the first documented instance of a spinal capillary hemangioma that mimics a cystic hemangioblastoma.
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  • 文章类型: Journal Article
    术后腹部粘连通常发生在腹部手术后;可以构建模仿腹膜组织的屏障膜以防止腹部粘连。为此,丝纤蛋白(SF)片用聚乙烯醇(PVA)和琼脂糖(AGA)以100:0、70:30、50:50、30:70和0:100的PVA:AGA比率涂覆,以产生复合抗粘附屏障,并允许我们确定合适的涂覆比率。膜的特征在于它们的分子组织,结构,和形态学使用傅里叶变换红外光谱仪(FT-IR),差示扫描量热仪(DSC),和扫描电子显微镜(SEM),分别。膜的物理和机械性能及其生物学性能(即,成纤维细胞增殖和侵袭)在体外测试。每个膜都显示出光滑和粗糙的表面特征。以100:0、70:30、50:50和30:70的比例涂覆有PVA:AGA的膜比涂覆有0:100PVA:AGA的膜表现出更多的-OH和酰胺III部分,从而影响了结构组织,降解,和成纤维细胞活力。0:100PVA:AGA涂层降解最快。涂覆有100:0和70:30PVA:AGA的屏障膜显示出减少的成纤维细胞增殖和附着。用70:30PVA:AGA涂覆的膜表现出稳定的外观,并且在潮湿条件下没有卷曲。因此,涂覆有70:30PVA:AGA的SF片材显示出作为用于进一步开发的抗粘附屏障膜的前景。
    Postoperative abdominal adhesions often occur after abdominal surgery; barrier membranes which mimic peritoneal tissue can be constructed to prevent abdominal adhesions. To this end, silk fibroin (SF) sheets were coated with polyvinyl alcohol (PVA) and agarose (AGA) at PVA:AGA ratios of 100:0, 70:30, 50:50, 30:70, and 0:100 to create a composite anti-adhesive barrier and allow us to identify a suitable coating ratio. The membranes were characterized in terms of their molecular organization, structure, and morphology using Fourier transform Infrared spectrometer (FT-IR), differential scanning calorimeter (DSC), and scanning electron microscope (SEM), respectively. The physical and mechanical properties of the membranes and their biological performance (i.e., fibroblast proliferation and invasion) were tested in vitro. Each membrane showed both smooth and rough surface characteristics. Membranes coated with PVA:AGA at ratios of 100:0, 70:30, 50:50, and 30:70 exhibited more -OH and amide III moieties than those coated with 0:100 PVA:AGA, which consequently affected structural organization, degradation, and fibroblast viability. The 0:100 PVA:AGA-coated degraded the fastest. Barrier membranes coated with 100:0 and 70:30 PVA: AGA demonstrated reduced fibroblast proliferation and attachment. The membrane coated with 70:30 PVA:AGA exhibited a stable appearance, and did not curl under wet conditions. Therefore, SF sheets coated with 70:30 PVA:AGA show promise as anti-adhesive barrier membranes for further development.
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  • 文章类型: Case Reports
    尽管气道异物吸入(FBA)在任何年龄段都很常见,肺部未识别和保留的异物可能导致严重的并发症,如肺脓肿或支气管扩张。在极少数情况下,FBA可能与许多其他疾病(例如哮喘,肿瘤,肺嗜酸性粒细胞增多)。这里,我们报道了一个罕见的9岁男孩错过FBA的病例,其胸部CT扫描提示左下叶有空洞性病变,模仿先天性肺气道畸形(CPAM)。然而,令人惊讶的是,柔性支气管镜检查发现花生滞留在左下叶的外侧基底段,随后由镊子取回,避免了不必要的手术肺叶切除术。因此,FBA可以模仿其他疾病(例如CPAM),并且可能需要高度怀疑和额外的诊断技术(例如柔性支气管镜)来区分它们。此外,在儿童呼吸道疾病的鉴别诊断中,即使没有误吸史,也应考虑FBA。
    Although airway foreign body aspiration (FBA) is a common occurrence in any age group, unrecognized and retained foreign bodies in lungs may result in severe complications, such as lung abscess or bronchiectasis. In rare cases, FBA may present with similar clinical features as many other diseases (e.g. asthma, tumor, pulmonary eosinophilia). Here, we report a rare case of missed FBA in a nine-year-old boy, whose chest CT scan was suggestive of a cavitary lesion in the left lower lobe mimicking congenital pulmonary airway malformation (CPAM). However, surprisingly, flexible bronchoscopy revealed a peanut lodged in the lateral basal segment of left lower lobe, which was subsequently retrieved by a forceps and avoided unnecessary surgical lobectomy. Therefore, FBA can mimic other disorders (e.g. CPAM), and a high index of suspicion and additional diagnostic techniques (e.g. flexible bronchoscopy) may be required to distinguish them. Additionally, FBA should be considered in the differential diagnosis of respiratory disorders in children even lack of aspiration history.
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  • 文章类型: Case Reports
    SARS-CoV-2感染是一种主要影响上呼吸道和肺的大流行。它可能导致已知的炎性风湿性疾病的再激活和/或各种肉芽肿性疾病的开始。坏死性结节性肉芽肿病(NSG)是一种罕见的疾病,可与恶性肿瘤混淆,肉芽肿性多血管炎,和结节病.在此,我们报道了SARS-CoV-2感染后NSG的发展,该感染模仿肉芽肿性血管炎。
    SARS-CoV-2 infection is a pandemic that affects predominantly upper airways and lungs. It may lead to reactivation of known inflammatory rheumatic diseases and/or initiation of various granulomatous disorders. Necrotising sarcoid granulomatosis (NSG) is a rare condition that can be confused with malignancy, granulomatosis with polyangiitis, and sarcoidosis. Herein we reported the development of NSG following a SARS-CoV-2 infection which mimicked granulomatosis with polyangiitis.
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  • 文章类型: Case Reports
    肺错构瘤是最常见的切除的肺良性肿瘤。间充质囊性亚型是由多个囊肿和结节组成的罕见且经常双侧发生的变体。在这里,我们介绍了一名无症状的70岁女性,其右肺门区域有一个大的,主要是囊性的生长。胸部计算机断层扫描和氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像将其起源追溯到右中叶。总体特征提示原发性肺癌或其他囊性肺病。因为经支气管肺活检未能建立组织学诊断,右中叶切除术采用胸腔镜手术.大体手术标本有一个单个且相当大(8.0×4.0cm)的囊性病变,其中包含多个黄白色结节。最终诊断为间叶囊性和软骨样错构瘤。这个特殊的案例值得注意,考虑到最初与原发性肺癌的临床相似。
    Pulmonary hamartoma is the most commonly resected benign neoplasm of lung. The mesenchymal cystic subtype is a rare and often bilaterally occurring variant composed of multiple cysts and nodules. Herein, we present an asymptomatic 70-year-old woman with a large and mostly cystic growth of right hilar region. Computed tomography of the chest and fluorodeoxyglucose positron emission tomography/computed tomography imaging traced its origins to right middle lobe. Overall features suggested primary lung cancer or perhaps other cystic lung disease.Because transbronchial lung biopsy failed to establish a histologic diagnosis, right middle lobectomy was undertaken by video-assisted thoracoscopic surgery. The gross surgical specimen harbored a single and sizeable (8.0 × 4.0 cm) cystic lesion containing multiple yellow-white nodules. A diagnosis of mesenchymal cystic and chondroid hamartoma was ultimately rendered. This particular case is noteworthy, given the initial clinical resemblance to primary lung cancer.
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  • 文章类型: Case Reports
    怀疑为恶性肿瘤的病变需要由多学科团队管理。放射学和病理学诊断方式的利用可确保正确的诊断,从而确保及时的干预。

    变形杆菌是革兰氏阴性棒。它是一种高度能动的细菌,属于肠杆菌科。由P引起的肺部感染和肺炎极为罕见,并且发生在患有慢性衰弱或慢性肺部疾病的患者中。
    一位65岁的老妇人出现干咳,劳累时呼吸困难,持续4个月的胸痛。她接受了包括抗生素在内的多种药物治疗,但症状没有得到任何缓解。进行胸部计算机断层扫描,报告左肺上叶有多个相关肺结节。印象是转移性肺部疾病合并急性感染。因此,对患者进行了重新评估,并进行了诊断性支气管镜检查,包括多次支气管内活检和支气管肺泡灌洗.革兰氏染色显示革兰氏阴性杆菌,细菌鉴定为奇异假单胞菌。
    怀疑为恶性肿瘤的肿块性病变应在多个医学学科的参与下进行处理,以确保正确和及时的诊断。这是为了避免管理失误。
    UNASSIGNED: Lesions that are suspected for malignancy need be managed by a multidisciplinary team. Utilization of radiological as well as pathological diagnostic modalities ensures correct diagnosis and thus timely intervention.
    UNASSIGNED:
    UNASSIGNED: Proteus mirabilis is a Gram-negative rod. It is a highly motile bacterium that belongs to the Enterobacteriaceae. Lung infection and pneumonia caused by p. mirabilis is extremely rare and occurs in patients with chronic debilitation or chronic lung disease.
    UNASSIGNED: A 65-year-Old Woman presented with dry cough, dyspnoea on exertion, and chest pain of 4 months\' duration. She received multiple medications including antibiotics but without any resolution of her symptoms. Computed Tomography scan of the chest was performed reported a tumor in the upper lobe of the left lung with multiple associated pulmonary nodules. The impression was that of metastatic lung disease with superimposed acute infection. Accordingly, the patient was reevaluated and a diagnostic bronchoscopy with multiple endobronchial biopsies and broncho-alveolar lavage was done. The gram stain showed Gram-Negative Bacilli and the bacteria identified P. mirabilis.
    UNASSIGNED: Mass lesions suspected for malignancy should be managed with involvement of multiple medical disciplines, to ensure correct and timely diagnosis. This is to avoid miss-management.
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  • 文章类型: Case Reports
    骨样骨瘤是一种良性骨肿瘤,通常起源于长骨的干phy端和干hy端区域。疼痛往往是首发症状,它可以模仿许多疾病。在这里,我们报告了一名36岁的男性患者,他主诉腰痛向右肢放射一年.在病人的病史中,物理治疗,富血小板血浆,普瑞巴林,使用了度洛西汀,唯一的好处是吲哚美辛。要求对股骨进行X光检查,磁共振成像证实了骨样骨瘤的诊断。尽管进行了治疗,但应牢记骨样骨瘤作为持续性疼痛的鉴别诊断。
    Osteoid osteoma is a benign bone tumor that commonly arises from the metaphyseal and diaphyseal regions of long bones. Pain is often the first symptom, and it can mimic many diseases. Herein, we report a 36-year-old male patient who presented with complaints of lower back pain radiating to the right extremity for a year. In the patient\'s history, physical therapy, platelet-rich plasma, pregabalin, and duloxetine were used, with the only benefit from indomethacin. An X-ray of the femur was requested, and the diagnosis of osteoid osteoma was confirmed by magnetic resonance imaging. Osteoid osteoma should be kept in mind as a differential diagnosis of persistent pain despite treatment.
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  • 文章类型: Case Reports
    一名61岁女性在体检中出现右心房肿块。左心超声造影显示右心房有一块32*23mm大小的肿块,附着在房间隔上;有一定程度的活动和变形。MRI显示右心房邻近房间隔约35*22毫米的肿块,被诊断为右心房粘液瘤。术中TEE显示肿块位于靠近下腔静脉的房间隔中,自发回声与肿块内的高回声图像形成对比。在体外循环下切除病灶。病理检查显示充盈缺损为房间隔血源性囊肿伴钙化。
    A 61-year-old female presented with right atrial mass during physical examination. Contrast-enhanced left heart echocardiography revealed a mass with the size of 32*23 mm in the right atrium, attached to the atrial septum; there was a certain degree of activity and deformation. MRI showed a mass of about 35*22 mm in the right atrium adjacent to the atrial septum, which was diagnosed with right atrial myxoma. Intraoperative TEE showed that the mass was located in the atrial septum close to the inferior vena cava and spontaneous echo contrast with hyperechoic images within the mass. The lesion was resected under cardiopulmonary bypass. Pathological examination revealed that the filling defect was an atrial septal hematogenous cyst with calcification.
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