Imaging features

成像特征
  • 文章类型: Case Reports
    背景:异位胸膜胸腺瘤和其他胸部肿瘤之间的影像学诊断复杂性很大,同时发生的T细胞淋巴细胞增多和骨转移的情况极为罕见。
    方法:一名51岁女性因呼吸困难和胸痛入院。影像学检查,她被发现左侧弥漫性和结节性胸膜增厚,左肺塌陷,第二胸椎受压。所有病灶18F-FDGPET/CT检查均显示明显的18F-FDG摄取。此外,她的外周血中有T细胞淋巴细胞增多,淋巴结,还有骨髓.排除恶性胸膜间皮瘤(MPM)后,肺癌胸膜转移,和T细胞淋巴瘤,明确诊断为异位胸膜胸腺瘤伴T细胞淋巴细胞增多和骨转移.
    结论:医师需要扩大对异位胸膜胸腺瘤影像学特征的认识。患有T细胞淋巴细胞增多症的病例可能表现出增加的侵袭性并易于发生骨转移。
    BACKGROUND: The diagnostic complexities that arise in radiographic distinction between ectopic pleural thymoma and other thoracic neoplasms are substantial, with instances of co-occurring T-cell lymphocytosis and osseous metastasis being exceedingly rare.
    METHODS: A 51-year-old woman was admitted to our hospital with dyspnea and chest pain. Upon imaging examination, she was found to have diffuse and nodular pleural thickening on the left side, collapse of the left lung and a compression in the second thoracic vertebrae. All lesions showed significant 18F-FDG uptake on 18F-FDG PET/CT examination. Furthermore, she exhibited T-cell lymphocytosis in her peripheral blood, lymph nodes, and bone marrow. After ruling out malignant pleural mesothelioma (MPM), lung cancer with pleural metastasis, and T-cell lymphoma, the definitive diagnosis asserted was ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis.
    CONCLUSIONS: Physicians need to expand their knowledge of the imaging features of ectopic pleural thymoma. Cases with T-cell lymphocytosis may exhibit increased aggressiveness and prone to bone metastasis.
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  • 文章类型: Journal Article
    肝脏是腹部原发性和继发性癌症的常见位置。放射科医生熟悉常见的良性和恶性肝脏肿瘤的典型影像学特征;然而,许多类型的肝肿瘤很少见。由于这些病变的稀有性,它们的典型成像模式可能不容易识别,这意味着在进行侵入性活检之前,可能不会发现或建议其潜在的病理特征。在这篇评论文章中,我们讨论了罕见和罕见的多发性肝肿瘤。有些有典型的成像模式,而其他是非特异性的,只能包括在鉴别诊断中。临床病史和血清学发现通常是提示这些实体的关键;因此,还讨论了这些内容,以使放射科医生熟悉每种情况的适当临床设置。这篇文章包括每个实体的图像丰富的描述,并附有描述超声检查的附图,计算机断层扫描,每个疾病过程的磁共振成像特征。讨论中还包括了几种疾病的新疗法和预后。
    The liver is a common location for both primary and secondary cancers of the abdomen. Radiologists become familiar with the typical imaging features of common benign and malignant liver tumors; however, many types of liver tumors are encountered infrequently. Due to the rarity of these lesions, their typical imaging patterns may not be easily recognized, meaning their underlying pathologic features may not be discovered or suggested until an invasive biopsy is performed. In this review article, we discuss multiple hepatic neoplasms that are both unusual and rare. Some have typical imaging patterns, whereas others are non-specific and can only be included in the differential diagnosis. The clinical history and serologic findings are often critical in suggesting these entities; therefore, these are also discussed to familiarize the radiologist with the appropriate clinical setting of each. The article includes an image-rich description of each entity with accompanying figures describing the ultrasonography, computed tomography, and magnetic resonance imaging features of each disease process. Novel therapies and prognosis of several of the diseases are also included in the discussion.
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  • 文章类型: Journal Article
    叶状肿瘤是一种罕见的乳腺纤维上皮肿瘤,组织学分类为良性,边界线,或恶性。准确的术前诊断允许正确的手术计划和避免再次手术。
    描述叶状肿瘤的临床表现和影像学特征,并区分良性和非良性(交界性和恶性)组。
    一项回顾性研究,对57例诊断为叶状肿瘤的患者进行了术前影像学检查(乳房X线摄影,超声,或CT胸部)和组织学确认。数据收集时间为2011年6月1日至2021年9月30日。根据ACRBI-RADS词典的第5版描述了叶状肿瘤的影像学特征。为了比较两组之间的差异,学生t检验,Wilcoxon秩和检验,卡方检验,和Fisher精确检验用于统计分析。采用logistic回归分析预测非良性叶状肿瘤。
    来自57名患者,病理结果良性43例,非良性叶状肿瘤14例。良性和非良性组之间的乳房X线照相和CT特征没有区别。非良性叶状肿瘤的绝经状态具有统计学意义,整个乳房受累,肿瘤大小大于10厘米,单变量分析和异质回波。经过多变量分析,绝经后状态(奇数比值=13.79,p=0.04)和多普勒超声检查发现边缘有血管(奇数比值=16.51,p=0.019)或无血管(奇数比值=8.45,p=0.047)均显著增加非良性叶状肿瘤的可能性.
    绝经期状态、边缘血管存在或多普勒超声检查血管缺失是非良性叶状肿瘤诊断的重要预测因子。
    UNASSIGNED: Phyllodes tumor is a rare fibroepithelial neoplasm of the breast, which is classified histologically as benign, borderline, or malignant. Accurate preoperative diagnosis allows the correct surgical planning and reoperation avoidance.
    UNASSIGNED: To describe the clinical presentation and radiologic features of phyllodes tumors and differentiate between benign and non-benign (borderline and malignant) groups.
    UNASSIGNED: A retrospective study of 57 patients with a diagnosis of phyllodes tumor who had preoperative imaging (mammography, ultrasound, or CT chest) and histological confirmation. The data was collected from 1 June 2011 to 30 September 2021. The imaging features of the phyllodes tumors were described according to the 5th edition of the ACR BI-RADS lexicon. For comparing between two groups, the student t-test, Wilcoxon rank sum test, Chi-square test, and Fisher\'s exact test were used for statistical analyses. The logistic regression analysis was calculated for non-benign phyllodes tumor prediction.
    UNASSIGNED: From 57 patients, the pathologic results were benign for 43 cases and non-benign phyllodes tumors for 14 cases. There was no differentiation of mammographic and CT features between benign and non-benign groups. Non-benign phyllodes tumors had the statistical significance of menopausal status, entire breast involvement, tumor size larger than 10 cm, and heterogeneous echo on univariable analysis. After multivariable analysis, menopausal status (odd ratios=13.79, p=0.04) and presence of vessels in the rim (odd ratios=16.51, p=0.019) or absent vascularity (odd ratios=8.45, p=0.047) on doppler ultrasound were significantly increased possibility of non-benign phyllodes tumor.
    UNASSIGNED: Menopausal status and presence of vessels in the rim or absent vascularity on Doppler ultrasound were important predictors for the diagnosis of non-benign phyllodes tumor.
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  • 文章类型: Journal Article
    大多数导管原位癌(DCIS)病变早期表现为钙化,可能是良性或恶性的.DCIS和良性乳腺疾病中可疑钙化的分类组对于早期评估患者的危险因素和计划治疗方案具有重要的临床意义。
    比较DCIS和良性乳腺疾病可疑钙化的影像学特征。
    2011年6月至2020年10月在Thammasat大学医院进行了101个可疑钙化的回顾性研究。通过乳房X线照相术引导的金属丝定位手术切除钙化。根据美国放射学会第五版乳腺成像报告和数据系统词典,对可疑钙化的乳房X线特征进行了审查。为了比较两组之间的差异,学生t检验,采用Fisher精确检验和Mann-WhitneyU检验进行统计分析。对DCIS预测进行logistic回归分析。
    101例可疑钙化灶的病理结果均为DCIS(30例)和良性乳腺疾病(71例)。线性形态和节段分布与DCIS显著相关(分别为p=0.003和p=0.024)。经过多变量分析,细线性钙化仍然显著升高DCIS的风险(奇数比率,51.72[95%置信区间:2.61,1022.89],p值为0.01),然而,预测DCIS的几率在任何分布之间均无统计学差异.
    与良性乳腺疾病相比,导管原位癌钙化具有对比的形态和分布特征。钙化描述符被认为是早期诊断的重要工具,可将DCIS与其他良性乳腺疾病区分开来。
    钙化描述符被认为是早期诊断和区分DCIS与其他良性乳腺疾病的重要手段。
    UNASSIGNED: Most ductal carcinoma in situ (DCIS) lesions manifest early as calcifications, which could be benign or malignant. The classified group of suspicious calcifications among DCIS and benign breast disease is clinically important to early evaluate patient risk factors and plan treatment options.
    UNASSIGNED: To compare imaging features of suspicious calcifications between DCIS and benign breast disease.
    UNASSIGNED: A retrospective study of 101 suspicious calcifications was performed at Thammasat University Hospital from June 2011 to October 2020. The calcifications were surgically excised by mammography-guided wire localisation. The mammographic features of the suspicious calcifications were reviewed according to the fifth edition of the American College of Radiology Breast Imaging-Reporting and Data System lexicon. For comparing between two groups, the student t-test, Fisher\'s exact test and Mann-Whitney U test were used for statistical analyses. The logistic regression analysis was calculated for DCIS prediction.
    UNASSIGNED: The pathologic results of all 101 suspicious calcifications were DCIS (30 cases) and benign breast disease (71 cases). Linear morphology and segmental distribution correlated significantly with DCIS (p = 0.003 and p = 0.024, respectively). After multivariable analysis, fine linear calcification still significantly elevated the risk of DCIS (odd ratios, 51.72 [95% confidence interval: 2.61, 1022.89], p-value of 0.01), however, the odds of predicting DCIS was not statistically significant different among any distribution.
    UNASSIGNED: Ductal carcinoma in situ calcification has contrasting morphology and distribution features compared to benign breast disease. The calcification descriptor is considered an important implement for early diagnosis and distinguishes DCIS from other benign breast conditions.
    UNASSIGNED: Calcification descriptor is considered an important implement for early diagnosis and distinguishment of DCIS from other benign breast conditions.
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  • 文章类型: Journal Article
    胶质瘤是最常见的原发性脑恶性肿瘤,约占所有中枢神经系统恶性肿瘤的80%。随着分子生物学的发展,胶质瘤的分子表型已被证明与诊断和治疗过程密切相关。脑胶质瘤的分子表型在指导治疗方案、评估治疗效果和预后方面也起着重要作用。然而,由于肿瘤的异质性和与手术切除肿瘤组织相关的创伤,分子表型分析在胶质瘤中的应用是有限的。随着成像技术的发展,功能磁共振成像(MRI)能够以非侵入性和无辐射的方式提供肿瘤的结构和功能信息。MRI对颅内病变的诊断非常重要。近年来,随着肿瘤分子诊断和影像学技术的发展,使用分子表型信息和影像学程序来评估肿瘤的治疗结果已成为热点。通过回顾近20年来发表的关于胶质瘤治疗和分子分型的相关文献,并参考最新的2020年NCCN治疗指南,总结不同分子表型脑胶质瘤的影像学特点及放化疗敏感性。在这篇文章中,本文简要综述了脑胶质瘤不同分子表型的影像学特点及其与脑胶质瘤放射敏感性和化疗敏感性的关系。
    Gliomas are the most common primary malignant tumors of the brain, accounting for about 80% of all central nervous system malignancies. With the development of molecular biology, the molecular phenotypes of gliomas have been shown to be closely related to the process of diagnosis and treatment. The molecular phenotype of glioma also plays an important role in guiding treatment plans and evaluating treatment effects and prognosis. However, due to the heterogeneity of the tumors and the trauma associated with the surgical removal of tumor tissue, the application of molecular phenotyping in glioma is limited. With the development of imaging technology, functional magnetic resonance imaging (MRI) can provide structural and function information about tumors in a noninvasive and radiation-free manner. MRI is very important for the diagnosis of intracranial lesions. In recent years, with the development of the technology for tumor molecular diagnosis and imaging, the use of molecular phenotype information and imaging procedures to evaluate the treatment outcome of tumors has become a hot topic. By reviewing the related literature on glioma treatment and molecular typing that has been published in the past 20 years, and referring to the latest 2020 NCCN treatment guidelines, summarizing the imaging characteristic and sensitivity of radiotherapy and chemotherapy of different molecular phenotypes of glioma. In this article, we briefly review the imaging characteristics of different molecular phenotypes in gliomas and their relationship with radiosensitivity and chemosensitivity of gliomas.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    Urachal肿瘤在临床实践中很少见,其中脐尿管腺癌最为常见。在这项研究中,我们报道了一例罕见的脐尿管血管周围上皮样细胞瘤,以提高我们对该疾病的认识。
    一名26岁男性患者因下腹痛住院。美国在膀胱上部显示出26mm×18mm的低回声肿块。MRI显示膀胱顶部前方有不规则肿块,在中线附近。肿瘤在T1WI上表现为低信号,在T2WI上表现为异质性高信号。此外,对比增强T1加权成像显示肿瘤明显的环形增强。患者接受了脐静脉肿瘤的手术切除,随后的病理检查显示诊断为脐尿管PEComa。手术后,患者接受定期随访评估,三年半后没有观察到复发或转移的证据。
    UrachalPEComa是一种罕见的间叶性肿瘤,通过影像学和临床症状对诊断提出了挑战。明确的诊断依赖于病理和免疫组织化学分析。由于脐带血PEComa的罕见,预后评估需要长期随访和评估更多病例。
    UNASSIGNED: Urachal tumors are rare in clinical practice, among which urachal adenocarcinoma is the most common. In this study, we report a rare case of urachal perivascular epithelioid cell tumor to improve our understanding of the disease.
    UNASSIGNED: A 26-year-old male patient was hospitalized for lower abdominal pain. The US showed a hypoechoic mass measuring 26mm × 18mm in the superior aspect of the bladder. MRI showed an irregular mass located anterior to the bladder roof, near the midline. The tumor exhibited hypointense on T1WI and heterogeneous hyperintense on T2WI. Additionally, contrast-enhanced T1-weighted imaging revealed obvious ring enhancement of the tumor. The patient underwent surgical resection of the urachal tumor, with subsequent pathological examination revealing a diagnosis of urachal PEComa. Following surgery, the patient underwent regular follow-up assessments, with no evidence of recurrence or metastasis observed after three and a half years.
    UNASSIGNED: Urachal PEComa is a rare mesenchymal tumor that presents challenges in diagnosis through imaging and clinical symptoms. Definitive diagnosis relies on pathological and immunohistochemical analysis. Due to the rarity of urachal PEComa, prognosis assessment necessitates long-term follow-up and evaluation of more cases.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    肺上皮样血管内皮瘤(PEH)是一种罕见的血管肿瘤,其早期诊断仍然具有挑战性。本研究旨在全面分析PEH的成像特征,并建立预测PEH的模型。
    对我们中心的PEH患者(n=25)和已发表病例(n=71)的影像学表现进行了回顾性和汇总分析。分别。提取相关计算机断层扫描(CT)图像,并将其用于构建深度学习模型,以识别PEH并与其他疾病区分。
    在这项研究中,双侧多发结节/肿块(n=19)似乎更常见,大多数结节小于2cm。除了常见的类型和功能,混合型(n=4)和孤立结节(n=4)的模式,还观察到点状钙化(5/25)和淋巴结肿大(10/25)。胸腔积液的存在与PEH的不良预后相关。深度学习模型,受试者工作特征曲线下面积(AUC)为0.71[95%置信区间(CI):0.69-0.72],训练集和测试集的区分精度分别为100%和74%。
    这项研究证实了PEH中成像发现的异质性,并显示了几种以前未描述的类型和特征。当前基于CT的深度学习模型具有临床应用潜力,未来需要进一步探索。
    UNASSIGNED: Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumour, and its early diagnosis remains challenging. This study aims to comprehensively analyse the imaging features of PEH and develop a model for predicting PEH.
    UNASSIGNED: Retrospective and pooled analyses of imaging findings were performed in PEH patients at our center (n=25) and in published cases (n=71), respectively. Relevant computed tomography (CT) images were extracted and used to build a deep learning model for PEH identification and differentiation from other diseases.
    UNASSIGNED: In this study, bilateral multiple nodules/masses (n=19) appeared to be more common with most nodules less than 2 cm. In addition to the common types and features, the pattern of mixed type (n=4) and isolated nodules (n=4), punctate calcifications (5/25) and lymph node enlargement were also observed (10/25). The presence of pleural effusion is associated with a poor prognosis in PEH. The deep learning model, with an area under the receiver operating characteristic curve (AUC) of 0.71 [95% confidence interval (CI): 0.69-0.72], has a differentiation accuracy of 100% and 74% for the training and test sets respectively.
    UNASSIGNED: This study confirmed the heterogeneity of the imaging findings in PEH and showed several previously undescribed types and features. The current deep learning model based on CT has potential for clinical application and needs to be further explored in the future.
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  • 文章类型: Journal Article
    多毛症是一种相对常见的疾病,影响约5%至15%的女性。它的定义是女性的终毛过度生长,主要影响依赖雄激素的地区,比如脸,腹部,臀部,和大腿。多毛症可以由多种病因引起,通常不会危及生命。然而,在某些情况下,多毛症可能是更严重的潜在病理的指标,比如肿瘤,这可能需要通过成像进一步阐明。在腹部和骨盆内,肾上腺和卵巢病变是首要考虑因素。本手稿的目的是回顾多毛症的各种腹内和骨盆内原因的病因和影像学特征。
    Hirsutism is a relatively common disorder which affects approximately 5% to 15% of women. It is defined by excessive growth of terminal hair in women, which primarily affects areas dependent on androgens, such as the face, abdomen, buttocks, and thighs. Hirsutism can be caused by a variety of etiologies, which are most often not lifethreatening. However, in some cases, hirsutism can be an indicator of more serious underlying pathology, such as a neoplasm, which may require further elucidation with imaging. Within the abdomen and pelvis, adrenal and ovarian pathologies are the primary consideration. The goal of this manuscript is to review the etiologies and imaging features of various intra-abdominal and intra-pelvic causes of hirsutism.
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