PDF(Pubmed)
Abstract：
BACKGROUND: The diagnostic complexities that arise in radiographic distinction between ectopic pleural thymoma and other thoracic neoplasms are substantial, with instances of co-occurring T-cell lymphocytosis and osseous metastasis being exceedingly rare.
METHODS: A 51-year-old woman was admitted to our hospital with dyspnea and chest pain. Upon imaging examination, she was found to have diffuse and nodular pleural thickening on the left side, collapse of the left lung and a compression in the second thoracic vertebrae. All lesions showed significant 18F-FDG uptake on 18F-FDG PET/CT examination. Furthermore, she exhibited T-cell lymphocytosis in her peripheral blood, lymph nodes, and bone marrow. After ruling out malignant pleural mesothelioma (MPM), lung cancer with pleural metastasis, and T-cell lymphoma, the definitive diagnosis asserted was ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis.
CONCLUSIONS: Physicians need to expand their knowledge of the imaging features of ectopic pleural thymoma. Cases with T-cell lymphocytosis may exhibit increased aggressiveness and prone to bone metastasis.
METHODS: A 51-year-old woman was admitted to our hospital with dyspnea and chest pain. Upon imaging examination, she was found to have diffuse and nodular pleural thickening on the left side, collapse of the left lung and a compression in the second thoracic vertebrae. All lesions showed significant 18F-FDG uptake on 18F-FDG PET/CT examination. Furthermore, she exhibited T-cell lymphocytosis in her peripheral blood, lymph nodes, and bone marrow. After ruling out malignant pleural mesothelioma (MPM), lung cancer with pleural metastasis, and T-cell lymphoma, the definitive diagnosis asserted was ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis.
CONCLUSIONS: Physicians need to expand their knowledge of the imaging features of ectopic pleural thymoma. Cases with T-cell lymphocytosis may exhibit increased aggressiveness and prone to bone metastasis.
摘要：
背景：异位胸膜胸腺瘤和其他胸部肿瘤之间的影像学诊断复杂性很大，同时发生的T细胞淋巴细胞增多和骨转移的情况极为罕见。
方法：一名51岁女性因呼吸困难和胸痛入院。影像学检查,她被发现左侧弥漫性和结节性胸膜增厚，左肺塌陷，第二胸椎受压。所有病灶18F-FDGPET/CT检查均显示明显的18F-FDG摄取。此外，她的外周血中有T细胞淋巴细胞增多,淋巴结,还有骨髓.排除恶性胸膜间皮瘤（MPM）后，肺癌胸膜转移，和T细胞淋巴瘤，明确诊断为异位胸膜胸腺瘤伴T细胞淋巴细胞增多和骨转移.
结论：医师需要扩大对异位胸膜胸腺瘤影像学特征的认识。患有T细胞淋巴细胞增多症的病例可能表现出增加的侵袭性并易于发生骨转移。
方法：一名51岁女性因呼吸困难和胸痛入院。影像学检查,她被发现左侧弥漫性和结节性胸膜增厚，左肺塌陷，第二胸椎受压。所有病灶18F-FDGPET/CT检查均显示明显的18F-FDG摄取。此外，她的外周血中有T细胞淋巴细胞增多,淋巴结,还有骨髓.排除恶性胸膜间皮瘤（MPM）后，肺癌胸膜转移，和T细胞淋巴瘤，明确诊断为异位胸膜胸腺瘤伴T细胞淋巴细胞增多和骨转移.
结论：医师需要扩大对异位胸膜胸腺瘤影像学特征的认识。患有T细胞淋巴细胞增多症的病例可能表现出增加的侵袭性并易于发生骨转移。
