PDF(Pubmed)
Abstract：
UNASSIGNED: Most ductal carcinoma in situ (DCIS) lesions manifest early as calcifications, which could be benign or malignant. The classified group of suspicious calcifications among DCIS and benign breast disease is clinically important to early evaluate patient risk factors and plan treatment options.
UNASSIGNED: To compare imaging features of suspicious calcifications between DCIS and benign breast disease.
UNASSIGNED: A retrospective study of 101 suspicious calcifications was performed at Thammasat University Hospital from June 2011 to October 2020. The calcifications were surgically excised by mammography-guided wire localisation. The mammographic features of the suspicious calcifications were reviewed according to the fifth edition of the American College of Radiology Breast Imaging-Reporting and Data System lexicon. For comparing between two groups, the student t-test, Fisher\'s exact test and Mann-Whitney U test were used for statistical analyses. The logistic regression analysis was calculated for DCIS prediction.
UNASSIGNED: The pathologic results of all 101 suspicious calcifications were DCIS (30 cases) and benign breast disease (71 cases). Linear morphology and segmental distribution correlated significantly with DCIS (p = 0.003 and p = 0.024, respectively). After multivariable analysis, fine linear calcification still significantly elevated the risk of DCIS (odd ratios, 51.72 [95% confidence interval: 2.61, 1022.89], p-value of 0.01), however, the odds of predicting DCIS was not statistically significant different among any distribution.
UNASSIGNED: Ductal carcinoma in situ calcification has contrasting morphology and distribution features compared to benign breast disease. The calcification descriptor is considered an important implement for early diagnosis and distinguishes DCIS from other benign breast conditions.
UNASSIGNED: Calcification descriptor is considered an important implement for early diagnosis and distinguishment of DCIS from other benign breast conditions.
UNASSIGNED: To compare imaging features of suspicious calcifications between DCIS and benign breast disease.
UNASSIGNED: A retrospective study of 101 suspicious calcifications was performed at Thammasat University Hospital from June 2011 to October 2020. The calcifications were surgically excised by mammography-guided wire localisation. The mammographic features of the suspicious calcifications were reviewed according to the fifth edition of the American College of Radiology Breast Imaging-Reporting and Data System lexicon. For comparing between two groups, the student t-test, Fisher\'s exact test and Mann-Whitney U test were used for statistical analyses. The logistic regression analysis was calculated for DCIS prediction.
UNASSIGNED: The pathologic results of all 101 suspicious calcifications were DCIS (30 cases) and benign breast disease (71 cases). Linear morphology and segmental distribution correlated significantly with DCIS (p = 0.003 and p = 0.024, respectively). After multivariable analysis, fine linear calcification still significantly elevated the risk of DCIS (odd ratios, 51.72 [95% confidence interval: 2.61, 1022.89], p-value of 0.01), however, the odds of predicting DCIS was not statistically significant different among any distribution.
UNASSIGNED: Ductal carcinoma in situ calcification has contrasting morphology and distribution features compared to benign breast disease. The calcification descriptor is considered an important implement for early diagnosis and distinguishes DCIS from other benign breast conditions.
UNASSIGNED: Calcification descriptor is considered an important implement for early diagnosis and distinguishment of DCIS from other benign breast conditions.
摘要：
■大多数导管原位癌（DCIS）病变早期表现为钙化，可能是良性或恶性的.DCIS和良性乳腺疾病中可疑钙化的分类组对于早期评估患者的危险因素和计划治疗方案具有重要的临床意义。
■比较DCIS和良性乳腺疾病可疑钙化的影像学特征。
■2011年6月至2020年10月在Thammasat大学医院进行了101个可疑钙化的回顾性研究。通过乳房X线照相术引导的金属丝定位手术切除钙化。根据美国放射学会第五版乳腺成像报告和数据系统词典，对可疑钙化的乳房X线特征进行了审查。为了比较两组之间的差异，学生t检验，采用Fisher精确检验和Mann-WhitneyU检验进行统计分析。对DCIS预测进行logistic回归分析。
■101例可疑钙化灶的病理结果均为DCIS（30例）和良性乳腺疾病（71例）。线性形态和节段分布与DCIS显著相关(分别为p=0.003和p=0.024)。经过多变量分析，细线性钙化仍然显著升高DCIS的风险(奇数比率，51.72[95%置信区间：2.61，1022.89]，p值为0.01)，然而,预测DCIS的几率在任何分布之间均无统计学差异.
■与良性乳腺疾病相比，导管原位癌钙化具有对比的形态和分布特征。钙化描述符被认为是早期诊断的重要工具，可将DCIS与其他良性乳腺疾病区分开来。
■钙化描述符被认为是早期诊断和区分DCIS与其他良性乳腺疾病的重要手段。
■比较DCIS和良性乳腺疾病可疑钙化的影像学特征。
■2011年6月至2020年10月在Thammasat大学医院进行了101个可疑钙化的回顾性研究。通过乳房X线照相术引导的金属丝定位手术切除钙化。根据美国放射学会第五版乳腺成像报告和数据系统词典，对可疑钙化的乳房X线特征进行了审查。为了比较两组之间的差异，学生t检验，采用Fisher精确检验和Mann-WhitneyU检验进行统计分析。对DCIS预测进行logistic回归分析。
■101例可疑钙化灶的病理结果均为DCIS（30例）和良性乳腺疾病（71例）。线性形态和节段分布与DCIS显著相关(分别为p=0.003和p=0.024)。经过多变量分析，细线性钙化仍然显著升高DCIS的风险(奇数比率，51.72[95%置信区间：2.61，1022.89]，p值为0.01)，然而,预测DCIS的几率在任何分布之间均无统计学差异.
■与良性乳腺疾病相比，导管原位癌钙化具有对比的形态和分布特征。钙化描述符被认为是早期诊断的重要工具，可将DCIS与其他良性乳腺疾病区分开来。
■钙化描述符被认为是早期诊断和区分DCIS与其他良性乳腺疾病的重要手段。
