■缺血性中风仍然是全球死亡率和发病率的主要因素。本研究旨在提供缺血性卒中患病率的最新评估。发病率,死亡率,和1990年至2021年的残疾调整寿命年(DALYs),特别侧重于将患病率调查与其他措施一起纳入。分析按性别分层,年龄,和全球社会人口指数(SDI),区域,和国家层面。
■这项研究的数据来自2021年全球疾病负担,受伤,和风险因素研究(GBD)。量化时间模式并评估缺血性卒中患病率(ASPR)的年龄标准化率趋势,发病率(ASIR),死亡率(ASDR),和DALYs,估计的年度百分比变化(EAPC)是在研究期间计算的。分析按性别分类,20个年龄类别,21个GBD地区,204个国家/地区,和5个SDI五分位数。R统计软件包V4.4.2用于统计分析和绘图说明。
■2021年,缺血性卒中的全球负担仍然很大,共有69,944,884.8例,每100,000个人的ASPR为819.5例(95%UI:760.3-878.7)。ASIR为每100,000人中92.4人(95%UI:79.8-105.8),而ASDR为每100,000人中44.2人(95%UI:39.3-47.8)。此外,年龄标准化DALY率为837.4/100,000(95%UI:763.7-905).区域,中高SDI的地区表现出最大的ASPR,ASIR,ASDR,和年龄标准化的DALY率,而高SDI地区的发病率最低。地理空间,撒哈拉以南非洲南部的ASPR最高,而东欧的ASIR最高。在东欧观察到最大的ASDR和年龄标准化的DALY率,中亚,以及北非,和中东。在国家中,加纳的ASPR最高,北马其顿拥有最高的ASIR和ASDR。此外,北马其顿还表现出最高的年龄标准化DALY率。
■具有中高和中SDI的地区继续经历ASPR升高,ASIR,ASDR和年龄标准化的DALY率。在撒哈拉以南非洲南部观察到最高的缺血性卒中负担,中亚,东欧,和中东。
■无。
UNASSIGNED: Ischemic stroke remains a major contributor to global mortality and morbidity. This study aims to provide an updated assessment of rates in ischemic stroke prevalence, incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021, specifically focusing on including prevalence investigation alongside other measures. The analysis is stratified by sex, age, and socio-demographic index (SDI) at global, regional, and national levels.
UNASSIGNED: Data for this study was obtained from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). To quantify temporal patterns and assess trends in age-standardized rates of ischemic stroke prevalence (ASPR), incidence (ASIR), mortality (ASDR), and DALYs, estimated annual percentage changes (EAPCs) were computed over the study period. The analyses were disaggregated by gender, 20 age categories, 21 GBD regions, 204 nations/territories, and 5 SDI quintiles. R statistical package V 4.4.2 was performed for statistical analyses and plot illustrations.
UNASSIGNED: In 2021, the global burden of ischemic stroke remained substantial, with a total of 69,944,884.8 cases with an ASPR of 819.5 cases per 100,000 individuals (95% UI: 760.3-878.7). The ASIR was 92.4 per 100,000 people (95% UI: 79.8-105.8), while the ASDR was 44.2 per 100,000 persons (95% UI: 39.3-47.8). Additionally, the age-standardized DALY rate was 837.4 per 100,000 individuals (95% UI: 763.7-905). Regionally, areas with high-middle SDI exhibited the greatest ASPR, ASIR, ASDR, and age-standardized DALY rates, whereas high SDI regions had the lowest rates. Geospatially, Southern Sub-Saharan Africa had the highest ASPR, while Eastern Europe showed the highest ASIR. The greatest ASDR and age-standardized DALY rates were observed in Eastern Europe, Central Asia, as well as North Africa, and the Middle East. Among countries, Ghana had the highest ASPR, and North Macedonia had both the highest ASIR and ASDR. Furthermore, North Macedonia also exhibited the highest age-standardized DALY rate.
UNASSIGNED: Regions with high-middle and middle SDI continued to experience elevated ASPR, ASIR, ASDR and age-standardized DALY rates. The highest ischemic stroke burden was observed in Southern Sub-Saharan Africa, Central Asia, Eastern Europe, and the Middle East.
UNASSIGNED: None.