PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to quantify the global cardiovascular disease (CVD) burden attributable to diet high in sugar-sweetened beverages (SSB) among adults aged 60 years and older using data from the Global Burden of Disease (GBD) Study 2019.
UNASSIGNED: We extracted data on CVD mortality, disability-adjusted life-years (DALYs), and risk-factor exposures from the GBD 2019 study for people aged 60 and older. Age-period-cohort models were used to estimate the overall annual percentage change in mortality and DALY rate (net drift, % per year), mortality and DALY rate for each age group from 1990 to 2019 (local drift, % per year), longitudinal age-specific rate corrected for period bias (age effect), and mortality and Daly rate for each age group from 1990 to 2019 (local drift, % per year). And period/cohort relative risk (period/cohort effect).
UNASSIGNED: Between 1990 and 2019, global age-standardized CVD mortality (ASMR) and disability-adjusted life years (DALY) rates attributable to high SSB intake decreased, with larger reductions in high-SDI regions. ASMR declined from 19.5 to 13 per 100,000 (estimated annual percentage change (EAPC): -1.46%) and ASDR declined from 345.8 to 220.6 per 100,000 (EAPC: -1.66%). Age-period-cohort analysis showed CVD deaths and DALYs increased exponentially with age, peaking at 85-89 years. Period effects indicated declining CVD mortality and DALY rates since 1999, especially in higher-SDI regions. Cohort effects demonstrated consistent risk declines across successive generations born between 1900 and 1959. Predictions suggest continuing decreases through 2045 globally, but slower declines in lower-SDI regions.
UNASSIGNED: In conclusion, this comprehensive assessment of global CVD burden among older adults attributable to high SSB intake highlights major achievements but also persistent areas needing attention. Favorable declining mortality and DALY rate trends reflect substantial progress in CVD control amid population growth and aging.
UNASSIGNED: We extracted data on CVD mortality, disability-adjusted life-years (DALYs), and risk-factor exposures from the GBD 2019 study for people aged 60 and older. Age-period-cohort models were used to estimate the overall annual percentage change in mortality and DALY rate (net drift, % per year), mortality and DALY rate for each age group from 1990 to 2019 (local drift, % per year), longitudinal age-specific rate corrected for period bias (age effect), and mortality and Daly rate for each age group from 1990 to 2019 (local drift, % per year). And period/cohort relative risk (period/cohort effect).
UNASSIGNED: Between 1990 and 2019, global age-standardized CVD mortality (ASMR) and disability-adjusted life years (DALY) rates attributable to high SSB intake decreased, with larger reductions in high-SDI regions. ASMR declined from 19.5 to 13 per 100,000 (estimated annual percentage change (EAPC): -1.46%) and ASDR declined from 345.8 to 220.6 per 100,000 (EAPC: -1.66%). Age-period-cohort analysis showed CVD deaths and DALYs increased exponentially with age, peaking at 85-89 years. Period effects indicated declining CVD mortality and DALY rates since 1999, especially in higher-SDI regions. Cohort effects demonstrated consistent risk declines across successive generations born between 1900 and 1959. Predictions suggest continuing decreases through 2045 globally, but slower declines in lower-SDI regions.
UNASSIGNED: In conclusion, this comprehensive assessment of global CVD burden among older adults attributable to high SSB intake highlights major achievements but also persistent areas needing attention. Favorable declining mortality and DALY rate trends reflect substantial progress in CVD control amid population growth and aging.
摘要：
■本研究旨在使用全球疾病负担（GBD）研究2019年的数据，量化60岁及以上成年人高糖饮料（SSB）的全球心血管疾病（CVD）负担。
■我们提取了有关CVD死亡率的数据，残疾调整寿命年(DALYs)，以及来自GBD2019研究的60岁及以上人群的风险因素暴露。使用年龄-时期-队列模型来估计死亡率和DALY率的总体年度百分比变化(净漂移，每年%)，1990年至2019年各年龄组的死亡率和死亡率(局部漂移，每年%)，校正周期偏差(年龄效应)的纵向特定年龄比率，以及1990年至2019年各年龄组的死亡率和戴利率(局部漂移，%/年)。和周期/队列相对风险(周期/队列效应)。
■在1990年至2019年期间，由于高SSB摄入量而导致的全球年龄标准化CVD死亡率（ASMR）和残疾调整寿命年（DALY）下降。高SDI地区的降幅更大。ASMR从19.5降至13/100,000（估计年度百分比变化（EAPC）：-1.46％），ASDR从345.8降至220.6/100,000（EAPC：-1.66％）。年龄时期队列分析显示，CVD死亡和DALYs随年龄呈指数增长，在85-89年达到顶峰。经期影响表明，自1999年以来，CVD死亡率和DALY率下降，特别是在SDI较高的地区。队列效应表明，在1900年至1959年间出生的连续几代人中，风险持续下降。预测表明，到2045年，全球将继续下降，但在SDI较低的地区下降速度较慢。
■总而言之，这项对由高SSB摄入量引起的老年人全球CVD负担的综合评估突出了重大成就,但也突出了需要关注的持续领域.有利的死亡率下降和DALY率趋势反映了在人口增长和老龄化期间CVD控制的实质性进展。
■我们提取了有关CVD死亡率的数据，残疾调整寿命年(DALYs)，以及来自GBD2019研究的60岁及以上人群的风险因素暴露。使用年龄-时期-队列模型来估计死亡率和DALY率的总体年度百分比变化(净漂移，每年%)，1990年至2019年各年龄组的死亡率和死亡率(局部漂移，每年%)，校正周期偏差(年龄效应)的纵向特定年龄比率，以及1990年至2019年各年龄组的死亡率和戴利率(局部漂移，%/年)。和周期/队列相对风险(周期/队列效应)。
■在1990年至2019年期间，由于高SSB摄入量而导致的全球年龄标准化CVD死亡率（ASMR）和残疾调整寿命年（DALY）下降。高SDI地区的降幅更大。ASMR从19.5降至13/100,000（估计年度百分比变化（EAPC）：-1.46％），ASDR从345.8降至220.6/100,000（EAPC：-1.66％）。年龄时期队列分析显示，CVD死亡和DALYs随年龄呈指数增长，在85-89年达到顶峰。经期影响表明，自1999年以来，CVD死亡率和DALY率下降，特别是在SDI较高的地区。队列效应表明，在1900年至1959年间出生的连续几代人中，风险持续下降。预测表明，到2045年，全球将继续下降，但在SDI较低的地区下降速度较慢。
■总而言之，这项对由高SSB摄入量引起的老年人全球CVD负担的综合评估突出了重大成就,但也突出了需要关注的持续领域.有利的死亡率下降和DALY率趋势反映了在人口增长和老龄化期间CVD控制的实质性进展。
