■治疗慢性眼部疾病如春季角膜结膜炎(VKC)的挑战之一,青光眼,眼表疾病是患者坚持局部用药。为了支持正确的滴眼液滴注,已经开发了用于单剂量和常规多剂量容器的多种递送助剂。
■要评估Dropaid™单剂量,设计用于单剂量容器的滴眼液递送辅助装置,对VKC患者的30名父母和护理人员进行了可用性研究.在评估将单个滴眼液从单剂量容器挤压到儿科医疗假人眼睛上的能力之后,使用11点Likert量表对各种特征进行评估:从“非常困难”(-5)到“非常容易”(5)。
■大多数参与者对打开单剂量单位(SDU)的任务进行了评分,准备,并将Dropayed™单剂量装置定位为“非常容易”。当从容器中提供单个滴眼液时,87%的参与者将Dropayed™单剂量装置评为“非常容易”或“容易”,中位数评分为+5.0(四分位数间距[IQR],4.0-5.0)。为了便于使用,84%的人认为分娩辅助工具要么“非常容易”,要么“容易”,中位数分数为+4.0(IQR,3.0-5.0)。大多数参与者(93%)将Dropayed™单剂量评为“非常舒适”或“舒适”,中位数为+5.0(IQR,4.0-5.0)。
■Dropaid™单剂量递送辅助设备在应用的所有阶段都表现出快速学习和易用性,包括打开容器,滴眼液给药,和处理的舒适性。尽管设计用于单剂量容器,以帮助VKC患者滴注滴眼液,Dropayed™单剂量可以在一系列其他眼部疾病(如青光眼和干眼)中提供更广泛的应用。
UNASSIGNED: One of the challenges of treating chronic ocular diseases like vernal keratoconjunctivitis (VKC), glaucoma, and ocular surface disease is patient adherence to topical medication. To support correct eye drop instillation, a variety of delivery aids have been developed for both single-dose and conventional multi-dose containers.
UNASSIGNED: To evaluate Dropaid™ Single-dose, an eye drop delivery aid designed for single-dose containers, a usability study was conducted on 30 parents and caregivers of patients with VKC. After assessing the ability to squeeze a single eye drop from the single-dose container onto the eye of a pediatric medical dummy, the delivery aid was evaluated using an 11-point Likert scale on a variety of characteristics: from \"very difficult\" (-5) to \"very easy\" (+5).
UNASSIGNED: The majority of participants rated the task of opening the single-dose units (SDUs), preparing, and positioning the Dropaid™ Single-dose device as \"very easy\". When providing a single eye drop from the container, 87% of participants rated the Dropaid™ Single-dose device as either \"very easy\" or \"easy\", with a median rating score of +5.0 (interquartile range [IQR], 4.0-5.0). For general ease of use, 84% considered the delivery aid as either \"very easy\" or \"easy\", with a median score of +4.0 (IQR, 3.0-5.0). Most participants (93%) rated Dropaid™ Single-dose as either \"very comfortable\" or \"comfortable\" to hold, with a median score of +5.0 (IQR, 4.0-5.0).
UNASSIGNED: The Dropaid™ Single-dose delivery aid demonstrated rapid learning and ease of use across all stages of application, including opening the container, eye drop administration, and handling comfort. Although designed for use with single-dose containers to help eye drop instillation in patients with VKC, Dropaid™ Single-dose may provide a wider utility across a range of other ocular diseases such as glaucoma and dry eye.