目的:过敏性结膜炎(AC)通常与干眼有关。本研究旨在评估不同亚组AC患者干眼的患病率。
方法:这种观察,横断面研究,在印度北部一个三级中心的眼科进行,包括132例AC患者。根据眼表疾病指数(OSDI)诊断干眼症(DED)。Schirmer\'stest,和泪膜破裂时间(TFBUT)。
结果:发现AC患者干眼的患病率在31%和36%之间。关于OSDI评分,20.45%的患者有轻度,18.18%中度,31.81%的人有严重的DED等级,分别。常年性过敏性结膜炎(PAC)患者的平均OSDI评分明显更高(29.82±12.41),其次是季节性过敏性结膜炎(SAC)(25.35±12.88),春季角膜结膜炎(VKC)患者最少(13.60±8.63)(p<0.0001),分别。在45.45%的PAC中发现TFBUT小于10s,SAC的30.43%,20%的VKC患者,分别。三组间平均TFBUT差异无统计学意义(p=0.683)。在45.45%的PAC中观察到<10mm的Schirmer试验值,SAC的43.47%,10%的VKC患者,分别。
结论:本研究揭示了AC患者中DED的高患病率。在不同类型的AC患者中,PAC的DED百分比最高,其次是SAC,而VKC最少,分别。
Allergic conjunctivitis (AC) is commonly associated with dry eye. This
study was conducted to assess the prevalence of dry eye in different subsets of AC patients.
This observational, cross-sectional
study, conducted in the Department of Ophthalmology of a tertiary center in north India, included 132 patients of AC. The diagnosis of dry eye disease (DED) was made on the basis of Ocular Surface Disease Index (OSDI), Schirmer\'s test, and tear film break-up time (TFBUT).
The prevalence of dry eye in AC patients was found to range between 31% and 36%. On OSDI scoring, 20.45% of patients had mild, 18.18% moderate, and 31.81% had a severe grade of DED, respectively. The mean OSDI score was noted to be significantly higher in patients with perennial allergic conjunctivitis (PAC) (29.82 ± 12.41), followed by seasonal allergic conjunctivitis (SAC) (25.35 ± 12.88), and least in the patients of vernal keratoconjunctivitis (VKC) (13.60 ± 8.63) (p < 0.0001), respectively. The TFBUT was found to be less than 10 s in 45.45% of PAC, 30.43% of SAC, and 20% of VKC patients, respectively. The difference between the mean TFBUT among the three groups was statistically insignificant (p = 0.683). Schirmer\'s test value of <10 mm was observed in 45.45% of PAC, 43.47% of SAC, and 10% of VKC patients, respectively.
This
study revealed a high prevalence of DED in patients with AC. Among the different types of AC patients, PAC had the highest percentage of DED followed by SAC and least in VKC, respectively.