PDF(Pubmed)
Abstract：
UNASSIGNED: Vernal Keratoconjunctivitis (VKC) has been determined to be highly prevalent in countries within the tropical climate region. However, little evidence from studies conducted within this region has been put forward to support this claim.
UNASSIGNED: To determine the prevalence and risk factors of VKC among a Ghanaian clinical cohort.
UNASSIGNED: A 3-year case-control study was conducted in a tertiary eye care institution, and medical records of patients who had been diagnosed of VKC between 2018 and 2021 were reviewed.
UNASSIGNED: Medical records of 3800 patients were reviewed. Some 359 cases of VKC were identified, with a population prevalence rate of 9.45%. Males comprised 57.1% of the population with VKC, with a male-to-female ratio of 1.33:1. The disease was more prevalent (40.8%) in children (≤17 years), and the overall odds of incidence decreased by 10% for a unit increase in age. Age and sex-adjusted models revealed significant positive associations between Keratoconus [aOR = 40.760, 95% CI -5.948 to 339.937], Rhinitis [cOR = 5.183, 95% CI -2.074 to 12.022] and VKC. However, the incidence of VKC was relatively less expressive among pterygium cases [cOR = 0.315, 95% CI -0.077 to 0.846].
UNASSIGNED: VKC is highly prevalent among children and is often associated with comorbidities of atopic origin that exacerbate the impact of the disease among this vulnerable population. It is imperative that clinicians provide holistic care for children with VKC.
UNASSIGNED: To determine the prevalence and risk factors of VKC among a Ghanaian clinical cohort.
UNASSIGNED: A 3-year case-control study was conducted in a tertiary eye care institution, and medical records of patients who had been diagnosed of VKC between 2018 and 2021 were reviewed.
UNASSIGNED: Medical records of 3800 patients were reviewed. Some 359 cases of VKC were identified, with a population prevalence rate of 9.45%. Males comprised 57.1% of the population with VKC, with a male-to-female ratio of 1.33:1. The disease was more prevalent (40.8%) in children (≤17 years), and the overall odds of incidence decreased by 10% for a unit increase in age. Age and sex-adjusted models revealed significant positive associations between Keratoconus [aOR = 40.760, 95% CI -5.948 to 339.937], Rhinitis [cOR = 5.183, 95% CI -2.074 to 12.022] and VKC. However, the incidence of VKC was relatively less expressive among pterygium cases [cOR = 0.315, 95% CI -0.077 to 0.846].
UNASSIGNED: VKC is highly prevalent among children and is often associated with comorbidities of atopic origin that exacerbate the impact of the disease among this vulnerable population. It is imperative that clinicians provide holistic care for children with VKC.
摘要：
■已确定春季角膜结膜炎（VKC）在热带气候地区的国家中非常普遍。然而,在该地区进行的研究中，很少有证据支持这一说法。
■确定加纳临床队列中VKC的患病率和危险因素。
■一项为期3年的病例对照研究是在一家三级眼科护理机构进行的，我们回顾了2018年至2021年间诊断为VKC的患者的医疗记录.
■回顾了3800例患者的病历。确定了约359例VKC，人群患病率为9.45%。男性占VKC人口的57.1％，男女比例为1.33:1。该疾病在儿童（≤17岁）中更为普遍（40.8％），随着年龄单位的增长，总体发病率下降了10%。年龄和性别调整模型显示圆锥角膜之间存在显著正相关[aOR=40.760,95%CI-5.948至339.937],鼻炎[cOR=5.183，95%CI-2.074至12.022]和VKC。然而,VKC在翼状胬肉病例中的表达相对较低[cOR=0.315,95%CI-0.077~0.846].
VKC在儿童中非常普遍，并且通常与特应性起源的合并症有关，这些合并症加剧了该疾病在该脆弱人群中的影响。临床医生必须为VKC儿童提供全面护理。
■确定加纳临床队列中VKC的患病率和危险因素。
■一项为期3年的病例对照研究是在一家三级眼科护理机构进行的，我们回顾了2018年至2021年间诊断为VKC的患者的医疗记录.
■回顾了3800例患者的病历。确定了约359例VKC，人群患病率为9.45%。男性占VKC人口的57.1％，男女比例为1.33:1。该疾病在儿童（≤17岁）中更为普遍（40.8％），随着年龄单位的增长，总体发病率下降了10%。年龄和性别调整模型显示圆锥角膜之间存在显著正相关[aOR=40.760,95%CI-5.948至339.937],鼻炎[cOR=5.183，95%CI-2.074至12.022]和VKC。然而,VKC在翼状胬肉病例中的表达相对较低[cOR=0.315,95%CI-0.077~0.846].
VKC在儿童中非常普遍，并且通常与特应性起源的合并症有关，这些合并症加剧了该疾病在该脆弱人群中的影响。临床医生必须为VKC儿童提供全面护理。
