PDF(Pubmed)
Abstract：
We report a rare case of ocular surface squamous neoplasia (OSSN) masquerading as pseudoepitheliomatous hyperplasia in chronic vernal keratoconjunctivitis (VKC). A 24-year-old man presented with a history of bilateral VKC since childhood with a superior limbal mass in the right eye. There was a history of use of intermittent corticosteroids in the past. He underwent impression cytology followed by excision biopsy with wide margins (no touch technique), cryotherapy and amniotic membrane transplantation. Histopathological analysis confirmed the diagnosis of OSSN with mild to moderate dysplasia. This case highlights the importance of strong clinical suspicion and detailed cytological and histopathological examination for early detection and management of OSSN.
摘要：
我们报告了一例罕见的眼表鳞状细胞瘤（OSSN）伪装成慢性春季角膜结膜炎（VKC）的假性上皮瘤增生。一名24岁男子从小就有双侧VKC病史，右眼上有角膜缘肿块。过去有使用间歇性皮质类固醇的历史。他接受了印模细胞学检查，然后进行了广泛的切缘活检（无触摸技术），冷冻和羊膜移植。组织病理学分析证实OSSN诊断为轻度至中度发育不良。此病例强调了强烈的临床怀疑和详细的细胞学和组织病理学检查对于OSSN的早期发现和管理的重要性。
