Perceived stress

感知压力
  • 文章类型: Journal Article
    当前的专业护理教育计划对临床实践采取各种极大的关注,以提供护理学生。
    为了评估护理学院护生在临床实践中的压力发生率和相关因素以及应对策略,和课莫大学,埃塞俄比亚,2024.
    在2024年1月1日至12日之间进行了基于设施的横截面设计研究。学生总数为421人。使用已验证的工具收集数据,并使用Epi-dataVersion3.1输入,并导出到SPSSVersion25进行分析。进行了二元逻辑回归,将p值<.05的变量纳入多变量分析。AOR和95%CI在p值<0.05时宣布具有统计学意义。
    压力和应对策略的患病率分别为58.4%(95%CI[53.6-62.8])和52.0%(95%CI[47.3-56.5])。男性,私人常规,和指导老师的指导与压力显着相关。19-24岁年龄组,等级低,住在大学宿舍,临床工作人员指导,指导员指导,询问不清楚的问题与应对策略显著相关。
    十分之六的护生有压力。作为男性,作为一个私人,和家人住在一起,和指导老师指导与压力显着相关。因此,管理与性别有关的问题,参加常规节目,住在大学宿舍,指导学生可以减轻临床实践中的压力负担。十分之五的护生有良好的应对策略。年龄较低的年龄组,等级低,住在大学宿舍,临床工作人员指导,指导员指导,向指导老师询问不清楚的问题与应对策略显着相关。因此,提高成绩,住在大学宿舍,临床工作人员和指导员指导,询问不清楚的问题可能会增强应对策略。
    UNASSIGNED: The current professional nursing education program adopts various great attention for clinical practice to supply nursing students.
    UNASSIGNED: To assess the prevalence and associated factors of stress and coping strategies of nursing students during clinical practice in the school of nursing, Wachemo University, Ethiopia, 2024.
    UNASSIGNED: A facility-based cross-sectional design study was conducted between January 1 and 12/2024. The total number of students was 421. Data were collected using the validated tool and entered using Epi-data Version 3.1 and exported to SPSS Version 25 for analysis. Binary logistic regression was done, and variables with a p-value of <.05 were taken into the multivariable analysis. Statistically significant was declared at a p-value of <.05 with AOR and 95% CI.
    UNASSIGNED: The prevalence of stress and coping strategies was 58.4% with 95% CI [53.6-62.8] and 52.0% with 95% CI [47.3-56.5] respectively. Male gender, private regular, and instructor guide were significantly associated with stress. Age group 19-24 years, having low grades, living in a university dorm, clinical staff guiding, instructor guiding, and asking unclear issues were significantly associated with coping strategies.
    UNASSIGNED: About six in ten nursing students have stress. Being male gender, being a private, living with families, and instructor guide are significantly associated with stress. Therefore, managing gender-related issues, attending regular programs, living in a university dorm, and guiding the students might reduce the burden of stress during clinical practice. About five in ten nursing students have good coping strategies. Being age group of lower years old, having low grades, living in a university dorm, clinical staff guiding, instructor guiding, and asking the instructor about unclear issues were significantly associated with coping strategies. Therefore, improving grades, living in a university dorm, clinical staff and instructor guidance, and asking about unclear issues might enhance coping strategies.
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  • 文章类型: Journal Article
    婴儿期和幼儿期睡眠紊乱会对父母的睡眠产生不利影响,从而影响父母的幸福感。然而,关于儿童睡眠问题和行为睡眠干预作为治疗如何影响产妇主观幸福感的研究很少。
    本研究旨在探讨有睡眠问题的儿童母亲的主观幸福感的发生率,以及实施两种行为睡眠干预措施是否改变了他们的幸福感。
    这项研究是在社区环境中进行的,父母自愿与南非的睡眠咨询公司联系。
    使用来自南非119位自愿接触睡眠咨询公司的母亲的数据,采用前测后测设计来调查生活满意度的变化,影响,夫妻满意,在实施睡眠干预后约3周,感觉到压力和抑郁。
    结果表明,有睡眠问题的孩子的母亲经历了中等到高的生活满意度和积极影响,尽管存在中度负面影响,夫妻满意度、压力和轻度抑郁提示主观幸福感可能下降。
    研究结果表明,通过父母在场的睡眠干预措施实施逐渐灭绝和灭绝可能会提高生活满意度,影响,压力和抑郁,但不能在短期内满足夫妻。
    这项研究有助于了解睡眠不足对母亲主观幸福感的影响,并提供了有关两种睡眠干预措施对改善母亲主观幸福感的益处的初步证据。
    UNASSIGNED: Disturbed sleep during infancy and early childhood can have a detrimental effect on parental sleep and consequently parental well-being. However, there is a paucity of research on how perceived child sleep problems and behavioural sleep interventions as treatment influence maternal subjective well-being.
    UNASSIGNED: This study aimed to explore the incidence of subjective well-being in mothers of children with sleep problems and whether implementing two behavioural sleep interventions changed their well-being.
    UNASSIGNED: The research was conducted in a community setting, with parents voluntarily approaching a sleep consultancy based in South Africa.
    UNASSIGNED: Using data from 119 mothers voluntarily approaching a sleep consultancy in South Africa, a pre-test-post-test design was employed to investigate changes in life satisfaction, affect, couple satisfaction, perceived stress and depression approximately 3 weeks after implementation of a sleep intervention.
    UNASSIGNED: Results indicate that mothers of children with sleep problems experienced moderate to high life satisfaction and positive affect although the presence of moderate negative affect, couple satisfaction and stress and mild depression suggest possible decreased subjective well-being.
    UNASSIGNED: Findings suggest implementation of graduated extinction and extinction with parental presence sleep interventions may improve life satisfaction, affect, stress and depression but not couple satisfaction in the short-term.
    UNASSIGNED: This study contributes towards understanding the effect of sleep loss on the subjective well-being of mothers and provides preliminary evidence regarding the benefits of two sleep interventions for improving maternal subjective well-being.
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  • 文章类型: Journal Article
    尽管有许多论文专注于工作中的正念,在常见的基于正念的压力减少(MBSR)计划中,我们关于流量体验和压力作为工作中最佳功能和幸福感指标的知识如何随着时间的推移而发展。从流动和压力的交易模型中,我们认为,在训练期间建立正念不仅会减少压力,还会增加心流体验。因此,我们研究了情绪衰竭的调节作用,放大了正念的有益效果。
    在准实验研究中,91名参与者在8周内每周完成问卷。实验组的46名参与者参加了MBSR计划,而45名参与者是非活动对照组的一部分。
    正念和流量随着时间的推移显示出显着的线性增加,而应力表现出线性下降。那些参加MBSR训练的人报告说,正念增加了,积极和消极地预测了流动和压力的轨迹,分别。情绪疲惫放大了正念轨迹对流动和压力轨迹的影响。
    这些发现表明,正念不仅可以减轻压力,还可以促进自我流动的体验,特别是对于长期枯竭的个体。然而,需要更多的研究来复制这些结果,并解决当前研究的局限性,包括准实验设计,使用自我报告措施,以及研究期间的辍学。
    UNASSIGNED: Despite numerous papers focusing on mindfulness at work, our knowledge about how flow experience and stress as indicators of optimal functioning and wellbeing at work evolve over time during the common mindfulness-based stress reduction (MBSR) program remains limited. Drawing from the transactional model of flow and stress, we argue that a build-up of mindfulness over the training duration not only leads to a decrease in stress but also an increase in flow experience. Thereby, we examine the moderating role of emotional exhaustion amplifying the beneficial effects of mindfulness.
    UNASSIGNED: In a quasi-experimental study, 91 participants completed weekly questionnaires over the course of 8 weeks. Forty six participants in the experimental group took part in the MBSR program, while 45 participants were part of an inactive control group.
    UNASSIGNED: Mindfulness and flow showed a significant linear increase over time, whereas stress exhibited a linear decrease. Those who participated in the MBSR training reported an increase in mindfulness that positively and negatively predicted the trajectories of flow and stress, respectively. Emotional exhaustion amplified the effects of the trajectory of mindfulness on the trajectories of flow and stress.
    UNASSIGNED: These findings suggest that mindfulness can not only reduce stress but can also foster the autotelic experience of flow, especially for chronically depleted individuals. However, more research is necessary to replicate these results and address the limitations of the current study, including the quasi-experimental design, the use of self-report measures, as well as the dropout during the study period.
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  • 文章类型: Journal Article
    年轻人的睡眠不好很普遍,然而中介变量在很大程度上是研究不足的,利用客观睡眠措施的相关工作有限。本研究调查了感知压力和沉思在年轻人特质正念与主观和客观睡眠质量之间的关系中的中介作用。
    总共170名健康成年人(18-37岁,M=20.8,SD=2.9)自我报告了特质正念,感知压力,和沉思。主要(N=140)和次要(N=30)样本均完成了匹兹堡睡眠质量指数(PSQI)以评估主观睡眠质量。次级样本(N=30)还提供了睡眠日记,以及评估客观睡眠质量的腕部肌动数据。进行了中介分析,以感知压力和沉思为中介,评估特质正念对睡眠质量的影响。
    特征正念与更好的主观睡眠质量呈正相关;这完全由感知压力介导,b=-0.08,95%CI[-.12,-0.06]。沉思与主观睡眠质量呈负相关,但不能介导特质正念与睡眠质量之间的关系,b=-0.01,95%CI[-.03,0.02]。只有特质正念与基于日记的睡眠评分相关,并且没有一项测量与基于肌动描记术的睡眠质量相关。
    这项研究表明,在年轻人中,感知压力是特质正念与主观睡眠质量之间关系的重要媒介,而不是沉思。这些发现对基于正念的治疗方法有意义,以解决年轻人中睡眠障碍的高患病率。在文献中增加机械细节。
    UNASSIGNED: Poor sleep among young adults is prevalent, yet the mediating variables are largely understudied, and there is limited relevant work utilizing objective sleep measures. The present study investigated the mediating effects of perceived stress and rumination in the relationship between trait mindfulness and subjective and objective sleep quality in young adults.
    UNASSIGNED: A total of 170 healthy adults (aged 18-37, M = 20.8, SD = 2.9) self-reported on trait mindfulness, perceived stress, and rumination. The primary (N = 140) and secondary (N = 30) samples both completed the Pittsburgh Sleep Quality Index (PSQI) to assess subjective sleep quality. The secondary sample (N = 30) additionally provided sleep diaries, as well as wrist-worn actigraphy data for assessing objective sleep quality. A mediation analysis was conducted to assess the effect of trait mindfulness on sleep quality with perceived stress and rumination as mediators.
    UNASSIGNED: Trait mindfulness was positively associated with better subjective sleep quality; this was fully mediated by perceived stress, b = -0.08, 95% CI [-.12, -0.06]. Rumination was negatively associated with subjective sleep quality but did not mediate the relationship between trait mindfulness and sleep quality, b = -0.01, 95% CI [-.03, 0.02]. Only trait mindfulness was correlated with diary-based sleep ratings, and none of the measures were associated with actigraphy-based sleep quality.
    UNASSIGNED: This study indicates that perceived stress is an important mediator in the relationship between trait mindfulness and subjective sleep quality among young adults, rather than rumination. These findings have implications for mindfulness-based therapeutic approaches to address the high prevalence of sleep disorders among young adults, adding mechanistic detail to the literature.
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  • 文章类型: Journal Article
    背景:家庭环境对年轻人的人格发展及其对生活满意度的评估具有重大影响。感知压力与生活满意度有关,但是这种关系也受到家庭环境的影响。本研究分析了大学生感知压力对生活满意度的影响以及家庭氛围的中介作用。
    方法:本研究招募了920名大学生。使用的仪器包括感知压力量表,对生活的满意度量表,和家庭社会气候量表,收集社会教育信息。
    结果:结果表明,感知压力对冲突和暴力的家庭气候都有显著的积极影响,而生活满意度受到这些负面家庭气候的负面影响。此外,支持性和凝聚力的家庭气候,除了表达感情和意见的困难,被发现对生活满意度有显著的积极影响。
    结论:这些发现强调了家庭系统在塑造个体状况方面的重要性,以及家庭系统如何调节压力与生活满意度之间的关系。
    BACKGROUND: The family environment has a significant influence on the personality development of young people and their assessment of life satisfaction. Perceived stress is related to life satisfaction, but this relationship is also influenced by the family context. The present study analysed the impact of perceived stress on life satisfaction and the mediating role of family climate in university students.
    METHODS: A sample of 920 university students was recruited for this study. The instruments used included the Perceived Stress Scale, the Satisfaction with Life Scale, and the Family Social Climate Scale, and socioeducational information was collected.
    RESULTS: The results indicate that perceived stress had a significant and positive effect on both conflictive and violent family climates, while life satisfaction was negatively impacted by these negative family climates. Additionally, supportive and cohesive family climates, along with difficulty expressing feelings and opinions, were found to have significant positive effects on life satisfaction.
    CONCLUSIONS: These findings highlight the importance of the family system in shaping individual conditions and how it can regulate the relationship between stress and life satisfaction.
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  • 文章类型: Journal Article
    在不断发展的教育环境中,大学教师经常发现自己处于无数压力源的十字路口,从机构需求到个人挑战。了解影响他们压力感知和应对机制的因素是至关重要的,不仅仅是为了他们的幸福,也是对整体教育质量的传授。这项研究试图调查性别之间错综复杂的关系,婚姻状况,机构隶属关系,以及它们对感知压力的集体影响,压力评估,高校教师的应对策略。300名大学教师的样本,根据性别平均分配,订婚了。使用包括感知压力量表(PSS)在内的工具,压力评估措施(SAM),简短的COPE,本研究的分析使用独立样本t检验和皮尔逊乘积矩相关来得出见解。研究结果表明,在压力感知和评估方面存在明显的性别差异,女教师表现出更高的水平。婚姻状况是压力和应对的重要调节因素,与未婚老师相比,已婚老师描绘了细微差别的压力,并通过报告的应对策略进行了评估。此外,在私营和政府机构的教师之间观察到感知压力和应对的显著差异,私人机构的教师表现出更高的压力水平。这项研究强调了巴基斯坦高校教师压力经历的多面性,受个人和制度决定因素的混合影响。这些见解对于旨在提高教师的福祉和效率的机构至关重要。然而,鉴于研究的特定文化背景,必须更加全球化,比较研究,确保全球教师的整体支持机制。
    In the evolving landscape of education, college teachers often find themselves at the crossroads of myriad stressors, ranging from institutional demands to personal challenges. Understanding the factors that influence their stress perceptions and coping mechanisms is pivotal, not just for their well-being, but also for the overall quality of education imparted. This study sought to investigate the intricate relationships between gender, marital status, institutional affiliation, and their collective impacts on perceived stress, stress appraisal, and coping strategies among college teachers. A sample of 300 college teachers, evenly split with reference to gender, was engaged. Employing tools including Perceived Stress Scale (PSS), Stress Appraisal Measure (SAM), and Brief COPE, the analysis of the study used independent samples t-test and Pearson Product Moment Correlation to derive insights. Findings revealed pronounced gender disparities in stress perception and appraisal, with women teachers manifesting heightened levels. Marital status emerged as a significant modulator of stress and coping, with married teachers depicting nuanced stress and its appraisal with reported coping strategies compared to their unmarried peers. Furthermore, a significant variance in perceived stress and coping was observed between teachers of private and governmental institutions, with private institution teachers displaying elevated stress levels. The study underscores the multifaceted nature of stress experiences among college teachers in Pakistan, influenced by a blend of personal and institutional determinants. These insights are pivotal for institutions aiming to enhance the well-being and effectiveness of their teachers. However, given the specific cultural context of the study, there is an imperative for more global, comparative research, ensuring holistic support mechanisms for teachers worldwide.
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  • 文章类型: Journal Article
    背景:脑膜瘤是最常见的原发性脑肿瘤,起源于脑膜-围绕大脑和脊髓的保护膜。脑膜瘤的几个充分研究的危险因素包括性别,年龄,辐射暴露,遗传因素,和荷尔蒙因素。此外,一个人的心理情绪状态对其整体健康和心理健康的影响,特别是压力,目前是一个重要和相关的讨论话题。
    目的:本病例对照研究旨在研究感知压力之间的关联,慢性压力,和成年患者的脑膜瘤。
    结果:研究包括病例,其中包括经组织学证实的脑膜瘤的成年患者,和控制,由无脑癌病史的成年患者组成。数据收集涉及使用三种类型的问卷。第一份问卷侧重于患者的个人信息,地理因素,和生活习惯。另外两份问卷“感知压力量表”和“慢性压力量表”用于评估感知压力和慢性压力。询问是由神经科医生进行的。使用MicrosoftExcel和Stata14进行数据分析。总的来说,148份问卷完成并纳入分析。参与者的平均年龄为45.60±13.90岁。两组中女性人数都超过男性。与没有脑膜瘤的患者相比,诊断为脑膜瘤的患者具有更高的感知高压力水平(p=.045)。没有脑膜瘤诊断的受访者报告说,在一般和环境问题上有更多的慢性压力(p=.004),财务问题(p=.006),工作(p<.001),无就业(p=.008),爱情与婚姻(p<.001),隔离(p<.001),和住所(p<.001)。脑膜瘤患者,然而,与无脑膜瘤患者相比,慢性应激较少。
    结论:这项研究显示,在我们的研究样本中,应激和脑膜瘤之间没有明显的联系。有必要进行更大样本量的匹配病例对照方法的进一步研究,以彻底评估压力在脑膜瘤患者中的潜在作用。
    BACKGROUND: Meningiomas are the most common type of primary brain tumor, originating from the meninges - the protective membranes that surround the brain and spinal cord. Several well-studied risk factors for meningiomas include gender, age, radiation exposure, genetic factors, and hormonal factors. Moreover, the influence of a person\'s psycho-emotional stateon their overall health and mental well-being, specifically stress, iscurrently a significant and relevant topic of discussion.
    OBJECTIVE: This case-control study aimed to study the association between perceived stress, chronic stress, and meningioma in adult patients.
    RESULTS: The study included cases, which comprised adult patients with histologically confirmed meningioma, and controls, consisting of adult patients with no history of brain cancer. Data collection involved the use of three types of questionnaires. The first questionnaire focused on patients\' personal information, geographic factors, and lifestyle habits. Two additional questionnaires \"The Perceived Stress Scale\" and \"The Chronic Stress Scale\" were employed to assess perceived stress and chronic stress. The questioning was conducted by a neurologist. Microsoft Excel and Stata 14 were used for the data analysis. Overall, 148 questionnaires were completed and included in the analyses. The average age of participants was 45.60 ± 13.90 years. Females outnumbered males in both groups. Patients with meningioma diagnosis had a higher level of perceived high stress compared to those without meningioma (p = .045). Respondents without a diagnosis of meningioma have reported having more chronic stress in general and ambient problems (p = .004), financial issues (p = .006), work (p < .001), non-employment (p = .008), love and marriage (p < .001), isolation (p < .001), and residence (p < .001). Patients with meningioma, however, had less chronic stress compared to meningioma-free patients.
    CONCLUSIONS: This study revealed no discernible connection between stress and meningioma within our study sample. Further research with matched case-control methodology with a larger sample size is warranted to thoroughly evaluate the potential role of stress in patients with meningioma.
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  • 文章类型: Journal Article
    慢性病对生活质量(QOL)和心理健康有负面影响。关于Brugada综合征(BrS)这一主题的相关数据有限。我们评估了BrS诊断对患者及其亲属与健康相关的QOL和心理状况的影响。
    患有BrS的患者及其亲属在诊断时(T0)接受了心理评估,诊断后1年和2年(T1和T2)使用心理QOL问卷,焦虑,抑郁症,压力,创伤后应激,和弹性资源。
    纳入了61名患者和39名亲属。与对照组相比,患者的身体生活质量增加(54.1±6.5vs.50.1±8.0,p=0.014),降低精神生活质量(43.2±11.8vs.49.6±9.1,p=0.018)和焦虑增加(9.9±6.6vs.T0时6.9±7.7,p=0.024);韧性评分降低(3.69±0.40vs.T1时3.96±0.55,p=0.008);弹性降低(3.69±0.35vs.3.96±0.55,p=0.019)和增加的焦虑评分(16.4±12.8vs.在T2时6.9±7.7,p=0.006)。亲戚表现出更高的压力(17.63±3.77vs.12.90±6.0,p=0.02)在T0和更高的焦虑评分在T0(13.5±7.6vs.6.9±7.7,p<0.001),T1(12.0±8.7vs.6.9±7.7,p=0.005),和T2(16.4±12.8vs.6.9±7.7,p=0.006)比对照组。在T0时,女性性别与患者的不良心理生活质量评分显着独立相关(比值比=0.10;95%置信区间=0.05-0.94;p=0.04)。
    BrS的诊断会损害患者及其亲属的生活质量和心理状况。诊断时,女性与患者的精神生活质量差独立相关。
    UNASSIGNED: Chronic diseases have a negative impact on quality of life (QOL) and psychological health. There are limited related data regarding this topic in Brugada syndrome (BrS). We evaluated the effects of the diagnosis of BrS on health-related QOL and psychological status among patients and their relatives.
    UNASSIGNED: Patients with BrS and their relatives underwent psychological evaluation at diagnosis (T0), 1 and 2 years after diagnosis (T1 and T2) using questionnaires on mental QOL, anxiety, depression, stress, post-traumatic stress, and resilience resources.
    UNASSIGNED: Sixty-one patients and 39 relatives were enrolled. Compared with controls, patients showed increased physical QOL (54.1 ± 6.5 vs. 50.1 ± 8.0, p = 0.014), reduced mental QOL (43.2 ± 11.8 vs. 49.6 ± 9.1, p = 0.018) and increased anxiety (9.9 ± 6.6 vs. 6.9 ± 7.7, p = 0.024) at T0; reduced resilience scores (3.69 ± 0.40 vs. 3.96 ± 0.55, p = 0.008) at T1; and reduced resilience (3.69 ± 0.35 vs. 3.96 ± 0.55, p = 0.019) and increased anxiety scores (16.4 ± 12.8 vs. 6.9 ± 7.7, p = 0.006) at T2. Relatives presented higher stress (17.63 ± 3.77 vs. 12.90 ± 6.0, p = 0.02) at T0 and higher anxiety scores at T0 (13.5 ± 7.6 vs. 6.9 ± 7.7, p < 0.001), T1 (12.0 ± 8.7 vs. 6.9 ± 7.7, p = 0.005), and T2 (16.4 ± 12.8 vs. 6.9 ± 7.7, p = 0.006) than controls. Female sex was significantly independently associated with worse mental QOL scores in patients at T0 (odds ratio = 0.10; 95% confidence interval = 0.05-0.94; p = 0.04).
    UNASSIGNED: The diagnosis of BrS impairs the QOL and psychological status of patients and their relatives. Female sex is independently associated with worse mental QOL in patients at diagnosis.
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  • 文章类型: Journal Article
    尽管有越来越多的证据表明肠道-大脑参与了精神疾病,功能数据仍然有限,以及其他微生物生态位的分析,例如阴道微生物群,缺乏与心理健康的关系。这项研究的目的是调查在患有精神疾病的临床诊断人群中观察到的肠道微生物组和心理健康之间的联系是否扩展到经历压力和抑郁症状的健康女性。此外,这项研究根据心理症状的水平检查了肠道微生物群的功能途径。此外,该研究旨在探讨未进行精神病诊断的年轻女性阴道微生物组和心理健康参数之间的潜在相关性.
    在这项横断面研究中,160名健康的丹麦女性(年龄在18-40岁之间)填写了经过验证的量表问卷,以测量压力和抑郁的症状以及饮食摄入的频率。在月经周期开始时收集粪便和阴道微生物群样品,并且还在周期第8-12天和第18-22天收集阴道样品。进行肠道和阴道微生物组的鸟枪宏基因组分析。使用京都基因和基因组百科全书(KEGG)进行功能分析,并在粪便样品中分析56个肠道脑模块。
    大肠杆菌属肠道中的相对丰度,副杆菌属,在抑郁症状升高的女性中,志贺氏菌较高。具有高感知压力的女性表现出大肠杆菌丰度增加的趋势,志贺氏菌,还有Blautia.其中,潜在致病属,埃希氏菌和志贺氏菌与神经活性通路的改变相关,如谷氨酸能,GABAeric,多巴胺能,和犬尿氨酸途径。阴道病症状在报告高水平压力和抑郁症状的女性中更为普遍。
    这项研究的结果支持了即使在健康的年轻女性中,微生物群对神经活性通路的影响的概念。这表明,针对肠道微生物组可能是未来精神病学干预的一种有希望的方法。
    UNASSIGNED: Despite mounting evidence of gut-brain involvement in psychiatric conditions, functional data remain limited, and analyses of other microbial niches, such as the vaginal microbiota, are lacking in relation to mental health. This aim of this study was to investigate if the connections between the gut microbiome and mental health observed in populations with a clinical diagnosis of mental illness extend to healthy women experiencing stress and depressive symptoms. Additionally, this study examined the functional pathways of the gut microbiota according to the levels of psychological symptoms. Furthermore, the study aimed to explore potential correlations between the vaginal microbiome and mental health parameters in young women without psychiatric diagnoses.
    UNASSIGNED: In this cross-sectional study, 160 healthy Danish women (aged 18-40 years) filled out questionnaires with validated scales measuring symptoms of stress and depression and frequency of dietary intake. Fecal and vaginal microbiota samples were collected at the beginning of the menstrual cycle and vaginal samples were also collected at cycle day 8-12 and 18-22. Shotgun metagenomic profiling of the gut and vaginal microbiome was performed. The Kyoto Encyclopedia of Genes and Genomes (KEGG) was used for functional profiling and 56 Gut Brain Modules were analyzed in the fecal samples.
    UNASSIGNED: The relative abundance in the gut of the genera Escherichia, Parabacteroides, and Shigella was higher in women with elevated depressive symptoms. Women with high perceived stress showed a tendency of increased abundance of Escherichia, Shigella, and Blautia. Amongst others, the potentially pathogenic genera, Escherichia and Shigella correlate with alterations in the neuroactive pathways such as the glutamatergic, GABAeric, dopaminergic, and Kynurenine pathways. Vaginosis symptoms were more prevalent in women reporting high levels of stress and depressive symptoms.
    UNASSIGNED: The findings of this study support the concept of a microbiota-associated effect on the neuroactive pathways even in healthy young women. This suggest, that targeting the gut microbiome could be a promising approach for future psychiatric interventions.
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  • 文章类型: Journal Article
    背景:医护人员(HCWs)在工作中经常面临多种压力源,尤其是那些上夜班的人。经历过痛苦的医护人员可能会发现很难采用压力管理方法,即使他们意识到压力和应对过程的影响。因此,可能需要进行个性化干预,以帮助陷入困境的医护人员弥合压力管理中的"知识-实践"差距,并有效缓解压力症状.
    目的:这项研究的主要目的是比较复杂的交互式多模式干预(CIMI)与自我指导的压力管理干预对陷入困境的HCW的压力症状的影响,以生理(心率变异性)衡量,心理(感知压力,精神痛苦,和主观幸福),和睡眠障碍(疲劳和嗜睡)指标。
    方法:我们进行了非随机,中国2家综合医院的对照研究。这项研究的参与者是245名HCWs,他们至少满足了抑郁症三个维度中的一个,焦虑,和应力量表。所有符合条件的个体都需要完成问卷并佩戴24小时Holter设备,以确定基线和干预后心率变异性指标的压力生理迹象。TheCIMI组接受了为期12周的在线干预,包括4个组成部分-移动压力管理指导,基于网络的微信社交网络,个性化反馈,还有一个护士教练,而对照组仅接受自我指导干预.
    结果:经过12周的干预,与基线水平相比,CIMI组的感知压力量表(PSS)评分显著降低(均差[MD]-5.31,95%CI-6.26至-4.37;P<.001).干预前后PSS评分的变化在CIMI组和对照组之间显示出显着差异(d=-0.64;MD-4.03,95%CI-5.91至-2.14;P<.001),效果是中等的。在生理测量方面,对照组(MD-9.56,95%CI-16.9至-2.2;P=.01)和CIMI组(MD-8.45,95%CI-12.68至-4.22;P<.001)均显示在正常临床范围内正常-正常间期(SDNN)的标准差显著降低;两组间无显著差异(d=0.03;MD1.11,95%CI-7.38~9.59;P=.80)。
    结论:TheCIMI是改善睡眠障碍的有效干预措施,以及部分痛苦的医护人员的心理压力措施。研究结果提供了客观的证据,为开发一种可适应和可访问的移动压力管理干预措施,但其长期影响应在未来的研究中进行研究。
    背景:ClinicalTrials.govNCT05239065;https://clinicaltrials.gov/ct2/show/NCT05239065。
    BACKGROUND: Health care workers (HCWs) frequently face multiple stressors at work, particularly those working night shifts. HCWs who have experienced distress may find it difficult to adopt stress management approaches, even if they are aware of the effects of stress and coping processes. Therefore, an individualized intervention may be required to assist distressed HCWs in bridging the \"knowledge-practice\" gap in stress management and effectively alleviating stress symptoms.
    OBJECTIVE: The main objective of this research was to compare the effects of a complex interactive multimodal intervention (CIMI) to self-guided stress management interventions on stress symptoms of distressed HCWs, as measured by physiological (heart rate variability), psychological (perceived stress, mental distress, and subjective happiness), and sleep disorder (fatigue and sleepiness) indicators.
    METHODS: We conducted a nonrandomized, controlled study in 2 Chinese general hospitals. The participants in this study were 245 HCWs who fulfilled at least 1 of the 3 dimensions on the Depression, Anxiety, and Stress Scale. All eligible individuals were required to complete a questionnaire and wear a 24-hour Holter device to determine the physiological signs of stress as indexed by heart rate variability at both baseline and after the intervention. The CIMI group received a 12-week online intervention with 4 components-mobile stress management instruction, a web-based WeChat social network, personalized feedback, and a nurse coach, whereas the control group simply received a self-guided intervention.
    RESULTS: After a 12-week intervention, the Perceived Stress Scale (PSS) scores reduced significantly in the CIMI group (mean difference [MD] -5.31, 95% CI -6.26 to -4.37; P<.001) compared to the baseline levels. The changes in PSS scores before and after the intervention exhibited a significant difference between the CIMI and control groups (d=-0.64; MD -4.03, 95% CI -5.91 to -2.14; P<.001), and the effect was medium. In terms of physiological measures, both the control group (MD -9.56, 95% CI -16.9 to -2.2; P=.01) and the CIMI group (MD -8.45, 95% CI -12.68 to -4.22; P<.001) demonstrated a significant decrease in the standard deviation of normal-to-normal intervals (SDNN) within the normal clinical range; however, there were no significant differences between the 2 groups (d=0.03; MD 1.11, 95% CI -7.38 to 9.59; P=.80).
    CONCLUSIONS: The CIMI was an effective intervention for improving sleep disorders, as well as parts of the psychological stress measures in distressed HCWs. The findings provide objective evidence for developing a mobile stress management intervention that is adaptable and accessible to distressed HCWs, but its long-term effects should be investigated in future research.
    BACKGROUND: ClinicalTrials.gov NCT05239065; https://clinicaltrials.gov/ct2/show/NCT05239065.
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