未经证实:中风是全球范围内致残和死亡的主要原因。关于抑郁症之间的关系有很多争论,焦虑,失眠,感知压力,和缺血性中风。此外,没有关于情绪调节功效的研究,这对于健康的情感和社会适应性的各个组成部分至关重要,正在进行。据我们所知,这是MENA地区的第一项研究,揭示了这些疾病与卒中风险之间的关系,旨在确定是否抑郁,焦虑,失眠,压力,而情绪应对方式可能是缺血性脑卒中发生的危险因素,并进一步探讨两种特定类型的情绪调节能力(认知重评和表达抑制)作为这些心理疾病与缺血性脑卒中风险关系的可能调节者。作为次要目标,我们试图确定这些预先存在的疾病如何影响卒中严重程度.
UNASSIGNED:这是一项病例对照调查研究,涉及在贝鲁特和黎巴嫩山的医院和康复中心收治的113名临床诊断为缺血性中风的黎巴嫩住院患者,和451名没有中风临床症状的性别匹配志愿者作为对照,从与病例相同的医院招募或在门诊就诊,治疗与中风或短暂性脑缺血发作无关的疾病或治疗,以及住院患者的访客或亲属(2020年4月至2021年4月)。数据是通过填写匿名纸质问卷收集的。
未经评估:根据回归模型的结果,抑郁症(AOR:1.232,95CI:1.008-1.506),感知压力(AOR:1.690,95CI:1.413-2.022),较低的教育水平(AOR:0.335,95CI:0.011-10.579),已婚(aOR:3.862,95CI:1.509-9.888)与缺血性卒中风险增加相关.适度分析显示,表达抑制对抑郁之间的关系有显著的调节作用,焦虑,感知压力,失眠,缺血性中风的风险,导致中风发生率的风险增加。相比之下,认知重新评估通过调节缺血性卒中风险与以下独立变量之间的关联显著降低缺血性卒中风险:感知压力和失眠.另一方面,我们的多项回归模型显示,与从未发生过卒中的人相比,卒中前期抑郁(aOR:1.088,95%CI:0.747~1.586)和感知压力(aOR:2.564,95%CI:1.604~4.100)患者发生中重度/重度卒中的几率显著更高.
未经评估:尽管有一些限制,我们的研究结果表明,抑郁或有压力的人更有可能发生缺血性卒中。因此,对抑郁和感知压力的原因和影响的更多研究可能为有助于降低卒中风险的预防策略提供新的方向.由于中风前抑郁和感知压力也被发现与中风严重程度密切相关,未来的研究应该评估卒中前抑郁之间的关系,感知压力,和中风严重程度,以更深入地了解这些变量之间的复杂相互作用。最后,这项研究揭示了情绪调节在抑郁关系中的作用,焦虑,感知压力,失眠,和缺血性中风。
UNASSIGNED: Stroke is a leading cause of disability and death worldwide. There are numerous debates regarding the relationship between depression, anxiety, insomnia, perceived stress, and ischemic stroke. Moreover, no research on the efficacy of emotion regulation, which is critical for various components of healthy affective and social adaptability, is being conducted. To the best of our knowledge, this is the first study in the MENA region to shed light on the relationship between these conditions and stroke risk, aiming to determine whether depression, anxiety, insomnia, stress, and the way of coping with emotions may be risk factors for ischemic stroke occurrence and to further investigate the ability of two specific types of emotion regulation (cognitive reappraisal and expressive suppression) as possible moderators of the relationship between these psychological diseases and ischemic stroke risk. As a secondary objective, we sought to determine how these pre-existing conditions affect stroke severity levels.
UNASSIGNED: This is a
case-control survey study involving 113 Lebanese inpatients with a clinical diagnosis of ischemic stroke admitted in hospitals and rehabilitation centers in Beirut and Mount Lebanon, and 451 gender-matched volunteers without clinical signs of stroke as controls recruited from the same hospitals as the cases or attending outpatient clinics for illnesses or treatments unconnected to stroke or transient ischemic attack, as well as visitors or relatives of inpatients (April 2020-April 2021). Data was collected by filling out an anonymous paper-based questionnaire.
UNASSIGNED: According to the outcomes of the regression model, depression (aOR: 1.232, 95%CI: 1.008-1.506), perceived stress (aOR: 1.690, 95%CI: 1.413-2.022), a lower educational level (aOR: 0.335, 95%CI: 0.011-10.579), and being married (aOR: 3.862, 95%CI: 1.509-9.888) were associated with an increased risk of ischemic stroke. The moderation analysis revealed that expressive suppression had a significant moderating effect on the relationship between depression, anxiety, perceived stress, insomnia, and ischemic stroke risk, resulting in an increased risk of stroke incidence. In contrast, cognitive reappraisal significantly reduced the risk of ischemic stroke by moderating the association between ischemic stroke risk and the following independent variables: perceived stress and insomnia. On the other hand, our multinomial regression model revealed that the odds of moderate to severe/severe stroke were significantly higher in people with pre-stroke depression (aOR: 1.088, 95% CI: 0.747-1.586) and perceived stress (aOR: 2.564, 95% CI: 1.604-4.100) compared to people who had never had a stroke.
UNASSIGNED: Despite several limitations, the findings of our study suggest that people who are depressed or stressed are more likely to have an ischemic stroke. Consequently, additional research into the causes and effects of depression and perceived stress may provide new directions for preventive strategies that can help reduce the risk of stroke. Since pre-stroke depression and perceived stress were also found to be strongly correlated with stroke severity, future studies should evaluate the association between pre-stroke depression, perceived stress, and stroke severity to gain a deeper understanding of the complex interaction between these variables. Lastly, the study shed new light on the role of emotion regulation in the relationship between depression, anxiety, perceived stress, insomnia, and ischemic stroke.