PDF(Pubmed)
Abstract：
BACKGROUND: Meningiomas are the most common type of primary brain tumor, originating from the meninges - the protective membranes that surround the brain and spinal cord. Several well-studied risk factors for meningiomas include gender, age, radiation exposure, genetic factors, and hormonal factors. Moreover, the influence of a person\'s psycho-emotional stateon their overall health and mental well-being, specifically stress, iscurrently a significant and relevant topic of discussion.
OBJECTIVE: This case-control study aimed to study the association between perceived stress, chronic stress, and meningioma in adult patients.
RESULTS: The study included cases, which comprised adult patients with histologically confirmed meningioma, and controls, consisting of adult patients with no history of brain cancer. Data collection involved the use of three types of questionnaires. The first questionnaire focused on patients\' personal information, geographic factors, and lifestyle habits. Two additional questionnaires \"The Perceived Stress Scale\" and \"The Chronic Stress Scale\" were employed to assess perceived stress and chronic stress. The questioning was conducted by a neurologist. Microsoft Excel and Stata 14 were used for the data analysis. Overall, 148 questionnaires were completed and included in the analyses. The average age of participants was 45.60 ± 13.90 years. Females outnumbered males in both groups. Patients with meningioma diagnosis had a higher level of perceived high stress compared to those without meningioma (p = .045). Respondents without a diagnosis of meningioma have reported having more chronic stress in general and ambient problems (p = .004), financial issues (p = .006), work (p < .001), non-employment (p = .008), love and marriage (p < .001), isolation (p < .001), and residence (p < .001). Patients with meningioma, however, had less chronic stress compared to meningioma-free patients.
CONCLUSIONS: This study revealed no discernible connection between stress and meningioma within our study sample. Further research with matched case-control methodology with a larger sample size is warranted to thoroughly evaluate the potential role of stress in patients with meningioma.
OBJECTIVE: This case-control study aimed to study the association between perceived stress, chronic stress, and meningioma in adult patients.
RESULTS: The study included cases, which comprised adult patients with histologically confirmed meningioma, and controls, consisting of adult patients with no history of brain cancer. Data collection involved the use of three types of questionnaires. The first questionnaire focused on patients\' personal information, geographic factors, and lifestyle habits. Two additional questionnaires \"The Perceived Stress Scale\" and \"The Chronic Stress Scale\" were employed to assess perceived stress and chronic stress. The questioning was conducted by a neurologist. Microsoft Excel and Stata 14 were used for the data analysis. Overall, 148 questionnaires were completed and included in the analyses. The average age of participants was 45.60 ± 13.90 years. Females outnumbered males in both groups. Patients with meningioma diagnosis had a higher level of perceived high stress compared to those without meningioma (p = .045). Respondents without a diagnosis of meningioma have reported having more chronic stress in general and ambient problems (p = .004), financial issues (p = .006), work (p < .001), non-employment (p = .008), love and marriage (p < .001), isolation (p < .001), and residence (p < .001). Patients with meningioma, however, had less chronic stress compared to meningioma-free patients.
CONCLUSIONS: This study revealed no discernible connection between stress and meningioma within our study sample. Further research with matched case-control methodology with a larger sample size is warranted to thoroughly evaluate the potential role of stress in patients with meningioma.
摘要：
背景：脑膜瘤是最常见的原发性脑肿瘤，起源于脑膜-围绕大脑和脊髓的保护膜。脑膜瘤的几个充分研究的危险因素包括性别，年龄,辐射暴露,遗传因素,和荷尔蒙因素。此外，一个人的心理情绪状态对其整体健康和心理健康的影响，特别是压力，目前是一个重要和相关的讨论话题。
目的：本病例对照研究旨在研究感知压力之间的关联，慢性压力，和成年患者的脑膜瘤。
结果：研究包括病例，其中包括经组织学证实的脑膜瘤的成年患者，和控制，由无脑癌病史的成年患者组成。数据收集涉及使用三种类型的问卷。第一份问卷侧重于患者的个人信息，地理因素,和生活习惯。另外两份问卷“感知压力量表”和“慢性压力量表”用于评估感知压力和慢性压力。询问是由神经科医生进行的。使用MicrosoftExcel和Stata14进行数据分析。总的来说,148份问卷完成并纳入分析。参与者的平均年龄为45.60±13.90岁。两组中女性人数都超过男性。与没有脑膜瘤的患者相比，诊断为脑膜瘤的患者具有更高的感知高压力水平（p=.045）。没有脑膜瘤诊断的受访者报告说，在一般和环境问题上有更多的慢性压力（p=.004），财务问题（p=.006），工作（p<.001），无就业（p=.008），爱情与婚姻（p<.001），隔离（p<.001），和住所（p<.001）。脑膜瘤患者,然而,与无脑膜瘤患者相比，慢性应激较少。
结论：这项研究显示，在我们的研究样本中，应激和脑膜瘤之间没有明显的联系。有必要进行更大样本量的匹配病例对照方法的进一步研究，以彻底评估压力在脑膜瘤患者中的潜在作用。
目的：本病例对照研究旨在研究感知压力之间的关联，慢性压力，和成年患者的脑膜瘤。
结果：研究包括病例，其中包括经组织学证实的脑膜瘤的成年患者，和控制，由无脑癌病史的成年患者组成。数据收集涉及使用三种类型的问卷。第一份问卷侧重于患者的个人信息，地理因素,和生活习惯。另外两份问卷“感知压力量表”和“慢性压力量表”用于评估感知压力和慢性压力。询问是由神经科医生进行的。使用MicrosoftExcel和Stata14进行数据分析。总的来说,148份问卷完成并纳入分析。参与者的平均年龄为45.60±13.90岁。两组中女性人数都超过男性。与没有脑膜瘤的患者相比，诊断为脑膜瘤的患者具有更高的感知高压力水平（p=.045）。没有脑膜瘤诊断的受访者报告说，在一般和环境问题上有更多的慢性压力（p=.004），财务问题（p=.006），工作（p<.001），无就业（p=.008），爱情与婚姻（p<.001），隔离（p<.001），和住所（p<.001）。脑膜瘤患者,然而,与无脑膜瘤患者相比，慢性应激较少。
结论：这项研究显示，在我们的研究样本中，应激和脑膜瘤之间没有明显的联系。有必要进行更大样本量的匹配病例对照方法的进一步研究，以彻底评估压力在脑膜瘤患者中的潜在作用。
