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  • 文章类型: Journal Article
    1985年,KWOH教授首次将机器人引入神经外科。从那以后,立体定向框架的进步,射线成像和神经导航导致了经典立体定向机器人的主导地位。使用学术数据库和搜索代理进行了全面的检索,以获取专业信息,截止日期是六月,2024.这表明许多新兴技术正在走到最前沿,包括震颤过滤,运动缩放,避障,力传感,为高效率做出了重大贡献,高精度,微创,和机器人辅助神经外科手术的确切疗效。这些技术已应用于创新的磁共振兼容神经外科机器人,比如Neuroarm和Neurobot,实时图像引导手术。尽管取得了这些进步,主要挑战被认为是空间方面的磁共振兼容性,材料,驾驶,和成像。未来的研究方向预计将集中在(1)机器人精确感知;(2)人工智能;和(3)远程手术的进步。
    In 1985, Professor KWOH first introduced robots into neurosurgery. Since then, advancements of stereotactic frames, radiographic imaging and neuronavigation have led to the dominance of classic stereotactic robots. A comprehensive retrieval was performed using academic databases and search agents to acquire professional information, with a cutoff date of June, 2024. This reveals a multitude of emerging technologies are coming to the forefront, including tremor filtering, motion scaling, obstacle avoidance, force sensing, which have made significant contributions to the high efficiency, high precision, minimally invasive, and exact efficacy of robot-assisted neurosurgery. Those technologies have been applied in innovative magnetic resonance-compatible neurosurgical robots, such as Neuroarm and Neurobot, with real-time image-guided surgery. Despite these advancements, the major challenge is considered as magnetic resonance compatibility in terms of space, materials, driving, and imaging. Future research directions are anticipated to focus on (1) robotic precise perception; (2) artificial intelligence; and (3) the advancement of telesurgery.
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  • 文章类型: Journal Article
    本研究介绍了一种通过卷积神经网络(CNN)优化点配置来增强机器人路径规划和导航的新方法。面对精确区域覆盖的挑战以及传统遍历和智能算法的低效率(例如,遗传算法,粒子群优化)在点布局中,提出了一种基于CNN的优化模型。该模型不仅解决了具有高斯分布特征的点配置中的速度和准确性问题,而且显着提高了机器人高效导航和高精度覆盖指定区域的能力。我们的方法从定义覆盖指数开始,然后是一个优化模型,该模型将多边形图像特征与高斯分布的可变性集成在一起。所提出的CNN模型使用从系统点配置生成的数据集进行训练,然后预测增强导航的最佳布局。我们的方法在测试数据集上实现了<8%的实验结果误差。结果验证了该模型在实现机器人系统高效、准确的路径规划方面的有效性。
    This study introduces a novel approach for enhancing robotic path planning and navigation by optimizing point configuration through convolutional neural networks (CNNs). Faced with the challenge of precise area coverage and the inefficiency of traditional traversal and intelligent algorithms (e.g., genetic algorithms, particle swarm optimization) in point layout, we proposed a CNN-based optimization model. This model not only tackles the issues of speed and accuracy in point configuration with Gaussian distribution characteristics but also significantly improves the robot\'s capability to efficiently navigate and cover designated areas with high precision. Our methodology begins with defining a coverage index, followed by an optimization model that integrates polygon image features with the variability of Gaussian distribution. The proposed CNN model is trained with datasets generated from systematic point configurations, which then predicts optimal layouts for enhanced navigation. Our method achieves an experimental result error of <8% on the test dataset. The results validate effectiveness of the proposed model in achieving efficient and accurate path planning for robotic systems.
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  • 文章类型: Journal Article
    结直肠癌是世界上最常见的癌症之一。虽然结肠镜检查是一种有效的筛查技术,引导内窥镜通过结肠检测息肉是一项挑战.观察到的表面的3D图可以增强对未筛选的结肠组织的识别并用作训练平台。然而,从视频片段重建冒号仍然很困难。基于学习的方法有望成为强大的替代方案,但需要大量的数据集。建立基准数据集,2022年EndoVis子挑战SimCol3D旨在促进结肠镜检查期间数据驱动的深度和姿势预测。该挑战赛作为MICCAI2022的一部分在新加坡举行。来自世界各地的六个团队以及来自学术界和工业界的代表参加了三个子挑战:合成深度预测,合成姿势预测,和真实姿势预测。本文描述了挑战,提交的方法,和他们的结果。我们表明,从合成结肠镜检查图像的深度预测是鲁棒可解决的,而姿态估计仍然是一个悬而未决的研究问题。
    Colorectal cancer is one of the most common cancers in the world. While colonoscopy is an effective screening technique, navigating an endoscope through the colon to detect polyps is challenging. A 3D map of the observed surfaces could enhance the identification of unscreened colon tissue and serve as a training platform. However, reconstructing the colon from video footage remains difficult. Learning-based approaches hold promise as robust alternatives, but necessitate extensive datasets. Establishing a benchmark dataset, the 2022 EndoVis sub-challenge SimCol3D aimed to facilitate data-driven depth and pose prediction during colonoscopy. The challenge was hosted as part of MICCAI 2022 in Singapore. Six teams from around the world and representatives from academia and industry participated in the three sub-challenges: synthetic depth prediction, synthetic pose prediction, and real pose prediction. This paper describes the challenge, the submitted methods, and their results. We show that depth prediction from synthetic colonoscopy images is robustly solvable, while pose estimation remains an open research question.
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  • 文章类型: Journal Article
    背景:精确微创闭合复位是微创内固定的前提。本文旨在探讨机器人辅助骨折复位系统(RAFR)在骨盆骨折治疗中的安全性和有效性,并分析其临床优势和存在的问题。
    方法:RAFR系统根据患者的术前三维(3D)CT扫描智能设计了最佳复位路径和目标位置。复位机械臂根据预先计划的复位路径自动地复位受影响的半骨盆。
    结果:平均剩余位移为6.65±3.59mm。根据Matta的标准,有7个优秀的,10好,3公平,优良率为85%。术后无并发症发生。
    结论:在我们的研究中,RAFR系统可以对大多数不稳定骨盆骨折患者进行准确、微创的闭合复位,能达到良好的骨折复位质量和近期疗效。
    BACKGROUND: Precise and minimally invasive closed reduction is the premise of minimally invasive internal fixation. This paper aims to explore the safety and efficacy of a robot-assisted fracture reduction system (RAFR) in the treatment of pelvic fractures and to analyze its clinical advantages and existing problems.
    METHODS: The RAFR system intelligently designed the optimal reduction path and target position based on a preoperative three-dimensional(3D) CT scan of the patient. The reduction robotic arm automatically reduced the affected hemipelvis according to the pre-planned reduction path.
    RESULTS: The average residual displacement was the 6.65 ± 3.59 mm. According to Matta\'s criteria, there were 7 excellent, 10 good, and 3 fair, and the excellent and good rate was 85%. No postoperative complications occurred.
    CONCLUSIONS: In our study, the RAFR system could complete accurate and minimally invasive closed reduction for most patients with unstable pelvic fractures, which could achieve good fracture reduction quality and short-term efficacy.
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  • 文章类型: Journal Article
    背景:肝胆管结石是一种复杂的疾病,在手术治疗中带来了挑战和困难。三维可视化技术结合荧光成像技术(3DVT-FI)可实现术前准确评估和术中实时导航。然而,肝胆管结石患者的3DVT-FI围手术期结局尚未见报道.我们旨在评估3DVT-FI治疗肝胆管结石的疗效。
    方法:对肝胆外科128例肝胆管结石病患者进行回顾性分析,珠江医院,2017年1月至2022年12月。其中,50例患者行3DVT-FI肝切除术(3DVT-FI组),78例患者行常规肝切除术,无3DVT-FI(CH组)。操作数据,术后肝功能指标,比较两组并发症发生率及结石残留情况。
    结果:两组患者术前基线资料差异无统计学意义(p>0.05)。与CH组相比,3DVT-FI组术中出血量较低(140.00±112.12vs.225.99±186.50mL,p=0.001),术中输血率较低(8.0%vs.23.1%,p=0.027)。术后并发症的总发生率没有显着差异(22.0%vs.35.9%,p=0.096)。3DVT-FI组有较低的即刻残余结石率(16.0%vs.34.6%,p=0.021)。3DVT-FI组无围手术期死亡,CH组有1例围手术期死亡。
    结论:3DVT-FI在手术安全性方面可能具有显著的益处,减少术中出血和减少结石残留物在肝切除术治疗肝胆管结石。
    Hepatolithiasis is a complex condition that poses challenges and difficulties in surgical treatment. Three-dimensional visualization technology combined with fluorescence imaging (3DVT-FI) enables accurate preoperative assessment and real-time intraoperative navigation. However, the perioperative outcomes of 3DVT-FI in hepatolithiasis have not been reported. We aim to evaluate the efficacy of 3DVT-FI in the treatment of hepatolithiasis.
    A retrospective analysis was performed on 128 patients who underwent hepatectomy for hepatolithiasis at the Department of Hepatobiliary Surgery, Zhujiang Hospital, between January 2017 and December 2022. Among them, 50 patients underwent hepatectomy using 3DVT-FI (3DVT-FI group), while 78 patients underwent conventional hepatectomy without 3DVT-FI (CH group). The operative data, postoperative liver function indices, complication rates and stone residue were compared between the two groups.
    There were no significant differences in preoperative baseline data between the two groups (p > 0.05). Compared with the CH group, the 3DVT-FI group exhibited lower intraoperative blood loss (140.00 ± 112.12 vs. 225.99 ± 186.50 mL, p = 0.001), and a lower intraoperative transfusion rate (8.0% vs. 23.1%, p = 0.027). The overall incidence of postoperative complications did not differ significantly (22.0% vs. 35.9%, p = 0.096). The 3DVT-FI group was associated with a lower immediate residual stone rate (16.0% vs. 34.6%, p = 0.021). There were no perioperative deaths in the 3DVT-FI group, while one perioperative death occurred in the CH group.
    The 3DVT-FI may offer significant benefits in terms of surgical safety, reduced intraoperative bleeding and decreased stone residue during hepatectomy for hepatolithiasis.
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  • 文章类型: Journal Article
    这项研究旨在评估利用手术指南的可行性,通过数字医疗技术设计,在眼眶外侧减压手术中。方法:总计,18例甲状腺相关眼病(TAO),纳入2018年9月至2022年8月在南昌大学附属眼科医院接受眼眶平衡减压手术的患者。所有TAO患者均行眼眶CT扫描,和Mimics21.0软件根据CT数据重建轨道的三维模型。采用3-matic13.0软件设计眼眶外侧减压手术截骨导向板,坚持手术有效性和安全性的标准。手术定位导向器采用GeomagicWrap21.0设计。一旦打印,手术导管用低温等离子体灭菌,并在手术过程中应用。在使用手术导航系统治疗的9名患者中,术中出现脑脊液漏并发症3例,和两个表现出沿着侧壁的骨去除不足。相比之下,在接受手术指南治疗的九名患者中,术中未观察到脑脊液漏或侧壁骨切除不足的证据,突出两个队列之间的统计学显著差异(p=0.046).对于患有严重TAO的患者,术后最佳矫正视力(BCVA)和眼球突出的改善显着。手术指南,采用数字医疗技术设计,已被证明是眼眶外侧减压手术的有效和安全的辅助工具。它不仅有助于减少术中并发症的发生率,同时也提高了手术的准确性和安全性。这些改进为临床实践中这一领域的持续探索提供了强有力的支持。
    This study aimed to assess the feasibility of utilizing a surgical guide, designed through digital medical technology, in lateral orbital decompression surgery. METHODS: In total, 18 patients with thyroid-associated ophthalmopathy (TAO), who underwent orbital balance decompression surgery at the Affiliated Eye Hospital of Nanchang University between September 2018 and August 2022, were included. Orbital CT scanning was performed on all patients with TAO, and Mimics 21.0 software was used to reconstruct a three-dimensional model of the orbit based on the CT data. The osteotomy guide plate for lateral orbital decompression surgery was designed using 3-matic 13.0 software, adhering to the criteria of surgical effectiveness and safety. The surgical positioning guide was designed using Geomagic Wrap 21.0. Once printed, the surgical guide was sterilized with low-temperature plasma and applied during surgery. Of the nine patients treated using a surgical navigation system, three cases experienced cerebrospinal fluid leakage complications during the procedure, and two exhibited inadequate bone removal along the lateral wall. In contrast, among the nine patients treated with surgical guides, no intraoperative cerebrospinal fluid leakage or evidence of insufficient lateral wall bone removal was observed, highlighting a statistically significant distinction between the two cohorts (p = 0.046). Postoperative improvements were notable in best-corrected visual acuity (BCVA) and exophthalmos for patients afflicted with extremely severe TAO. The surgical guide, designed with digital medical technology, has been shown to be an effective and secure auxiliary tool in lateral orbital decompression surgery. It not only aids in reducing the incidence of intraoperative complications, but also enhances the accuracy and safety of surgery. These improvements offer robust support for continued exploration in this field within clinical practice.
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  • 文章类型: Journal Article
    背景与目的:青少年特发性脊柱侧凸(AIS)是一种普遍存在的三维脊柱疾患,具有多因素的发病机理,包括遗传学和环境因素。治疗选择包括非手术和手术治疗。手术干预在畸形矫正方面显示出积极的结果,疼痛缓解,和改善心脏和肺功能。手术并发症,包括过度失血和神经功能缺损,在2.27-12%的病例中报告。导航辅助技术,比如O形臂系统,一直是最近的焦点,精度更高。本研究旨在评估O形臂导航辅助下AIS患者一期后路器械融合的结果和并发症。材料和方法:这项回顾性研究评估了55例AIS患者(12-28岁),他们在2016年6月至2023年8月期间接受了由O-arm导航支持的一期后方器械矫正。我们检查了放射学手术结果(初始矫正率,校正率损失,最后一次随访纠正率)和并发症作为主要结果。患者的特点,术中失血,操作时间,融合水平的数量,并记录了螺杆密度。结果:73例患者中,55符合纳入标准。平均年龄16.67岁,以女性为主(78.2%)。手术结果显示出实质性的初始校正(58.88%)和在最后一次随访中持续的积极放射学影响(56.56%)。围手术期并发症,包括主要和次要,发生在18.18%的病例中。两名患者经历了严重的并发症。失血量(509.46mL)和手术时间(402.13min)与文献范围相当。趋势分析表明,在研究期间,手术时间和失血量有所改善。结论:O形臂导航辅助的一期后路器械对于AIS矫正手术证明是可靠的,实现显著和持续的积极放射学结果,更低的校正损失,减少术中失血,和没有植入物相关的并发症。尽管面临挑战,我们的研究证明了这种手术方法的有效性和成熟度.
    Background and Objectives: Adolescent idiopathic scoliosis (AIS) is a prevalent three-dimensional spinal disorder, with a multifactorial pathogenesis, including genetics and environmental aspects. Treatment options include non-surgical and surgical treatment. Surgical interventions demonstrate positive outcomes in terms of deformity correction, pain relief, and improvements of the cardiac and pulmonary function. Surgical complications, including excessive blood loss and neurologic deficits, are reported in 2.27-12% of cases. Navigation-assisted techniques, such as the O-arm system, have been a recent focus with enhanced precision. This study aims to evaluate the results and complications of one-stage posterior instrumentation fusion in AIS patients assisted by O-arm navigation. Materials and Methods: This retrospective study assesses 55 patients with AIS (12-28 years) who underwent one-stage posterior instrumentation correction supported by O-arm navigation from June 2016 to August 2023. We examined radiological surgical outcomes (initial correction rate, loss of correction rate, last follow-up correction rate) and complications as major outcomes. The characteristics of the patients, intraoperative blood loss, operation time, number of fusion levels, and screw density were documented. Results: Of 73 patients, 55 met the inclusion criteria. The average age was 16.67 years, with a predominance of females (78.2%). The surgical outcomes demonstrated substantial initial correction (58.88%) and sustained positive radiological impact at the last follow-up (56.56%). Perioperative complications, including major and minor, occurred in 18.18% of the cases. Two patients experienced a major complication. Blood loss (509.46 mL) and operation time (402.13 min) were comparable to the literature ranges. Trend analysis indicated improvements in operation time and blood loss over the study period. Conclusions: O-arm navigation-assisted one-stage posterior instrumentation proves reliable for AIS corrective surgery, achieving significant and sustained positive radiological outcomes, lower correction loss, reduced intraoperative blood loss, and absence of implant-related complications. Despite the challenges, our study demonstrates the efficacy and maturation of this surgical approach.
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  • 文章类型: Journal Article
    J形转弯交叉口是一种新颖的道路设计,可减少交叉口的冲突点,通过限制高速公路对面的小路的直线穿越和左转运动。交叉路口设计的新颖性可能导致驾驶员的错误和不满。这项研究检查了幼稚或首次驾驶员在首次和早期接触新颖的交叉路口设计时最初如何导航J转弯。36名以往J型转弯经验和知识有限的参与者参加了一项模拟研究,以检查他们在平衡的三个模拟J型转弯交叉路口接受J型转弯和左转弯导航性能的情况,每个具有三个标牌级别之一。结果显示,参与者犯了稍微频繁的小错误(例如,低效的车道选择)和明显更多的主要错误(例如,错过U形转弯)在第一个J形转弯曝光期间,这些误差在随后的曝光期间趋于下降,而中度严重错误(例如,危险的变道)略有增加。模拟驾驶暴露后,参与者的J转弯接受度显着下降。在经历重大严重错误的参与者中,J-turn接受度的下降幅度更大;然而,更频繁的小错误与接受度增加相关.标牌级别对错误影响不大,但参与者更喜欢改进标志或道路标记来指导穿越运动。这项工作表明,应利用先进的教育计划和社区活动来为驾驶员准备如何导航J转弯,而不是仅依靠J转弯暴露来提高驾驶员的表现和接受度。
    The J-turn intersection is a novel roadway design which decreases the points of conflict at an intersection, by restricting straight crossing and left-turning movements from the minor road across the highway. The novelty of the intersection design may lead to driver errors and dissatisfaction. This study provides an examination of how naïve or first-time drivers may initially navigate J-turns during their first and early exposures to the novel intersection design. Thirty-six participants with limited previous experience and knowledge of J-turns participated in a simulation study to examine their acceptance of J-turns and left turning navigational performance at three simulated J-turn intersections in counterbalanced order, each featuring one of three signage levels. Results revealed participants committed slightly more frequent minor errors (e.g., inefficient lane selection) and significantly more major errors (e.g., missed U-turn) during the first J-turn exposure and these errors tended to decline during subsequent exposures, while moderate severity errors (e.g., risky lane change) slightly increased. Participants\' J-turn acceptance significantly declined following simulated driving exposure. The decline in J-turn acceptance was found to be greater among participants who experienced major severity errors; however, more frequent minor errors were associated with increased acceptance. Signage level had little effect on errors, but participants preferred improved signage or on-road markings to guide crossing movements. This work suggests that advanced educational programs and community initiatives should be utilized to prepare drivers for how to navigate J-turns rather than only rely on J-turn exposure to improve driver performance and acceptance.
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  • 文章类型: Journal Article
    目的:探讨锥形束CT(CBCT)标记和融合图像引导技术在数字减影血管造影(DSA)图像中无血管外漏的肾脏破裂出血病例中应用的可行性。
    方法:这是一项回顾性病例对照研究,包括43例因肾破裂出血和难以止血而接受经导管动脉栓塞的患者。将患者分为两组:CBCT组(在血管造影中没有观察到血管外漏的病例)和对照组(在血管造影中具有清晰可识别的目标血管的病例)。收集并分析基线特征和临床结果。
    结果:结果显示,对照组和CBCT组在手术时间和术中输血方面没有统计学上的显着差异(P>.05)。该研究表明,与对照组相比,CBCT组的肉眼血尿改善率明显更高(P<0.05)。CBCT组显示血红蛋白增加较大,肌酐增加较小。对照组临床成功率为87.5%,CBCT组为90.9%(P>.05)。
    结论:标记和融合图像引导技术在没有造影剂血管外漏的肾脏破裂出血病例中是有用的。技术是安全的,可行,而且有效,我们认为它优于纯粹的DSA指导。
    结论:建议使用标记和融合图像引导技术来克服介入过程中无法检测到目标血管的挑战。该技术被认为是不劣于纯DSA引导的介入程序,其中目标血管是清楚可识别的。
    OBJECTIVE: To explore the feasibility of using marking and fusion image-guided technique with cone-beam CT (CBCT) in cases of kidney ruptured haemorrhage without extravascular leakage in digital subtraction angiography (DSA) images.
    METHODS: This is a retrospective case-control study that included 43 patients who underwent transcatheter arterial embolization for kidney ruptured haemorrhage and difficult haemostasis. The patients were divided into two groups: the CBCT group (cases without extravascular leakage observed in angiography) and the control group (cases with clearly identifiable target vessels in angiography). The baseline characteristics and clinical outcomes were collected and analysed.
    RESULTS: The results showed no statistically significant differences in the duration of the procedure and intraoperative blood transfusion between the control and CBCT groups (P > .05). The study clarified that the CBCT group had a significantly higher rate of improvement of gross haematuria compared to the control group (P < .05). The CBCT group showed a greater increase in haemoglobin and a lesser increase in creatinine. The clinical success rates were 87.5% in the control group and 90.9% in the CBCT group (P > .05).
    CONCLUSIONS: The marking and fusion image-guided technique is useful in cases of kidney ruptured haemorrhage without extravascular leakage of contrast agent. The technique is safe, feasible, and effective, and we believe it is superior to purely DSA-guidance.
    CONCLUSIONS: The use of the marking and fusion image-guided technique is recommended to overcome the challenge of undetectable target vessels during interventional procedures. This technique is considered as non-inferior to purely DSA-guided interventional procedures where the target vessels are clearly identifiable.
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  • 文章类型: Randomized Controlled Trial
    目的:计算机导航在关节炎膝关节全膝关节置换术(TKA)中的价值仍存在争议。这项研究的目的是评估与更新的对准原理相关的导航TKA的价值。
    方法:这项前瞻性随机对照试验连续纳入38例患者(76膝),并随机分配到两组。记录人口统计学数据和围手术期数据。膝关节冠状面排列(CPAK)分类用于对膝关节排列表型进行分类。测量影像学结果并进一步进行亚组分析。使用患者报告的结果测量(PROM)评估临床结果。记录手术相关并发症。
    结果:体质比对TKA后CPAK表型的分布与天然队列相当,而机械排列的TKA将表型分布从I型和II型显著改变为V型和IV型。最终植入物的定位在组间是不同的,体质对齐的TKA具有较大的cTCA(P=0.004),接合线倾角(P=.006),关节线距离(P=.033)和较小的sFCA(P=.013)。亚组分析表明,在导航TKA中,组件定位的实际精度更高,尤其是畸形>10°的膝关节(P<.05)。体质匹配组患者术后3个月HSS评分较高(P=0.002)。导航组中的一名患者因轻微创伤而遭受股骨针部位骨折。
    结论:计算机导航TKA允许恢复体质对齐,并最大限度地减少软组织释放,与机械对齐相比,这可能与更好的早期结果相关。
    OBJECTIVE: The value of computer navigation in total knee arthroplasty (TKA) for arthritic knees continues to be debated. The purpose of this study was to evaluate the value of navigated TKA associated with updated alignment philosophy.
    METHODS: This prospective randomized controlled trial enrolled 38 consecutive patients (76 knees) and were randomly assigned to both groups. The demographic data and perioperative data were recorded. The coronal plane alignment of the knee (CPAK) classification was used to classify knee alignment phenotypes. Radiographic outcomes were measured and subgroup analysis was further performed. Clinical outcomes were evaluated using patient-reported outcome measures (PROMs). Surgery-related complications were recorded.
    RESULTS: The distribution of CPAK phenotypes following constitutional aligned TKA was equivalent to the native cohort, whereas the mechanical aligned TKA dramatically altered the phenotype distribution from type I and type II to type V and type IV. Final implant positioning was different between groups, with constitutional aligned TKA having larger cTCA (P = .004), joint line obliquity (P = .006), joint line distance (P = .033) and smaller sFCA (P = .013). Subgroup analysis showed higher actual accuracy of component positioning was achieved in navigated TKA, especially in knees with deformity of > 10° (P < .05). Patients reported higher HSS score at three months postoperatively in constitutional aligned group (P = .002). One patient in navigated group suffered femoral pin site fracture caused by a minor trauma.
    CONCLUSIONS: Computer navigated TKA allows for restoration of constitutional alignment and minimizes soft tissue release, which when compared to mechanical alignment may be associated with superior early outcomes.
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