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  • 文章类型: Journal Article
    在自然环境中,感官系统在电机输出的闭环中运行,由此,行动塑造了随后的感官体验。这方面的一个主要例子是所需的感觉运动处理,以对准一个人的行进方向,或航向,以一个人的目标,我们称之为转向的行为。在转向中,电机输出工作,以消除航向和目标之间的误差,修改过程中的后续错误。行为的闭环性质使得确定确定性和非确定性过程如何对行为做出贡献具有挑战性。我们通过应用非参数来克服这一点,在两个实验环境中,对通过虚拟环境操纵的猴子的行为数据进行基于线性核的分析。在给定的背景下,结果与以前的工作一致,将变换描述为二阶线性系统。经典的,例如,这样的二阶模型的参数与肢体的物理特性(诸如通常被假定为近似恒定的粘度和刚度)相关联。相比之下,我们发现,在这些和其他参数中,各个任务的拟合内核差异很大,提示神经和生物力学过程中上下文相关的变化。我们还将残差拟合到一个简单的噪声模型中,发现噪声的形式在环境和动物中都高度保守。引人注目的是,装配的噪音也与以前在人类转向任务中发现的噪音非常匹配。总之,这项工作提出了一种基于内核的分析,该分析表征了闭环感觉运动任务的确定性和非确定性组件的上下文依赖性。
    我们使用非参数系统识别技术来评估确定性和非确定性贡献对闭环行为的上下文依赖性。经典方法假定感觉输入和运动输出之间的固定转换。这里,我们揭示了行为背景下测量的感觉运动转换的强烈变化。相比之下,转换中的噪声在上下文中表现出一致的形式,主题,和物种。一起,这项工作演示了上下文如何影响闭环行为的系统和随机组件。
    In natural circumstances, sensory systems operate in a closed loop with motor output, whereby actions shape subsequent sensory experiences. A prime example of this is the sensorimotor processing required to align one\'s direction of travel, or heading, with one\'s goal, a behavior we refer to as steering. In steering, motor outputs work to eliminate errors between the direction of heading and the goal, modifying subsequent errors in the process. The closed-loop nature of the behavior makes it challenging to determine how deterministic and nondeterministic processes contribute to behavior. We overcome this by applying a nonparametric, linear kernel-based analysis to behavioral data of monkeys steering through a virtual environment in two experimental contexts. In a given context, the results were consistent with previous work that described the transformation as a second-order linear system. Classically, the parameters of such second-order models are associated with physical properties of the limb such as viscosity and stiffness that are commonly assumed to be approximately constant. By contrast, we found that the fit kernels differed strongly across tasks in these and other parameters, suggesting context-dependent changes in neural and biomechanical processes. We additionally fit residuals to a simple noise model and found that the form of the noise was highly conserved across both contexts and animals. Strikingly, the fitted noise also closely matched that found previously in a human steering task. Altogether, this work presents a kernel-based analysis that characterizes the context-dependence of deterministic and non-deterministic components of a closed-loop sensorimotor task.
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  • 文章类型: Journal Article
    行人在非约束环境中的行为很难预测。在可穿戴机器人技术中,这构成了挑战,由于下肢外骨骼和活动矫形器等设备需要支持不同的步行活动,包括水平行走和爬楼梯。虽然固定的运动轨迹可以很容易地支持,这些活动之间的切换很难预测。此外,预计未来几年对这些设备的需求将上升。在这项工作中,我们提出了一种用于可穿戴机器人的云软件系统,基于地理制图技术和人类活动识别(HAR)。该系统旨在通过提供事后的信息来为周围的行人提供上下文。该系统已部分实现和测试。结果表明,这是一个可行的概念,具有很大的可扩展性前景。
    The behavior of pedestrians in a non-constrained environment is difficult to predict. In wearable robotics, this poses a challenge, since devices like lower-limb exoskeletons and active orthoses need to support different walking activities, including level walking and climbing stairs. While a fixed movement trajectory can be easily supported, switches between these activities are difficult to predict. Moreover, the demand for these devices is expected to rise in the years ahead. In this work, we propose a cloud software system for use in wearable robotics, based on geographical mapping techniques and Human Activity Recognition (HAR). The system aims to give context to the surrounding pedestrians by providing hindsight information. The system was partially implemented and tested. The results indicate a viable concept with great extensibility prospects.
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  • 文章类型: Journal Article
    归巢通常是动物行为和空间生态的关键方面。迁移被认为是一种野生动物管理策略,可以减少人与野生动物的对抗,但是如果动物试图回到它们原来的捕获位置,这种策略可能不会有效。将动物从可能发生人与野生动物互动的地点转移是一种广泛但有争议的解决冲突的干预措施。在印度,蛇通常是这种易位的主体,但是,与居民蛇相比,关于易位蛇行为的信息很少。印度蟒蛇(蟒蛇),印度次大陆最大的食肉动物之一,被IUCN列为濒临威胁。我们对Moyar河谷的14只成年印度蟒蛇的运动进行了为期两年的无线电追踪研究(2018年12月至2020年12月),在Sathyamangalam和Mudumalai老虎保护区内。14条蟒蛇中有11条从捕获地点转移了0.28-55.7公里,虽然3条蟒蛇没有易位:6条易位短距离(距离捕获<5公里;范围0.28-4.67公里),2个被转移到中等距离(距捕获位置9-11公里),和3个被转移到长距离(从捕获位置21-55.7公里)。六只蛇中的四只短距离移动,都回到了原始捕获位置的500米以内,并且所有6个返回超过60%的转移距离到初始捕获位置。在两条中等距离的蛇中,两者都回到了捕获地点的1.1公里范围内(~90%的距离)。三只长距离易位的蛇都没有成功返回其捕获地点。在释放的前2个月内,移位的蟒蛇的净移动距离比常驻蛇大。基于这些结果,长距离易位可能是一种有效的策略,以尽量减少人与蟒蛇的冲突,而短距离或中距离易位不太可能成功。然而,需要对易位蛇的长期存活以及可以防止释放后直接异常运动行为的软释放方法进行更多研究。
    Homing is often a critical aspect of an animal\'s behavioural and spatial ecology. Translocation is considered to be a wildlife management strategy that could reduce human-wildlife confrontation, but this strategy may not be effective if animals attempt to home to their original capture location. Translocation of animals from sites where possible human-wildlife interaction occurs is a widespread but controversial intervention to resolve conflicts. In India, snakes are often the subject of such translocations, but there is a paucity of information on the behaviour of translocated snakes compared to resident snakes. The Indian python (Python molurus), one of the largest carnivores in the Indian subcontinent, is classified as Near Threatened by the IUCN. We conducted a two-year radio-tracking study (December 2018 to December 2020) on the movements of 14 adult Indian pythons in the Moyar River Valley, within the Sathyamangalam and Mudumalai Tiger Reserves. Eleven of the 14 pythons were translocated 0.28-55.7 kms from their capture locations, while 3 pythons were not translocated: 6 were translocated short distances (<5 km from capture; range 0.28-4.67 kms), 2 were translocated to medium distances (9-11 kms from capture location), and 3 were translocated to long distances (21-55.7 kms from capture location). Four of the six snakes translocated short distances all returned to within 500 m of their original capture locations, and all 6 returned over 60 % of the translocated distance to the initial capture location. Of the two snakes translocated medium distances, both returned to within 1.1 km of the capture location (∼90 % of the distance home). None of the three snakes that were translocated long distances successfully returned to their capture locations. Translocated pythons exhibited greater net movement distances than resident snakes within the first 2 months of release. Based on these results, long-distance translocation may be an effective strategy to minimize human-python conflict, while short or medium distance translocation is unlikely to be successful. However, more research is needed about the long-term survival of translocated snakes as well as soft-release methodologies that could prevent aberrant movement behaviour directly following release.
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  • 文章类型: Journal Article
    使用从步行者携带的智能手机记录的惯性数据的寻路系统具有提高盲人行人的移动性独立性的巨大潜力。用于定位的行人航位推算(PDR)算法需要估计步行者的步长。先前的工作表明,通过使用简单的机器学习算法处理智能手机记录的惯性数据,可以可靠地预测步长。然而,这项先前的工作只考虑了有视力的步行者,其步态可能与使用长手杖或导盲犬的盲人步行者不同。在这项工作中,我们表明,在盲人步行者上进行测试时,根据来自有视力的步行者的数据训练的步长估计网络表现不佳,并且使用来自盲人步行者的数据进行重新训练可以显着提高步长预测的准确性。
    Wayfinding systems using inertial data recorded from a smartphone carried by the walker have great potential for increasing mobility independence of blind pedestrians. Pedestrian dead-reckoning (PDR) algorithms for localization require estimation of the step length of the walker. Prior work has shown that step length can be reliably predicted by processing the inertial data recorded by the smartphone with a simple machine learning algorithm. However, this prior work only considered sighted walkers, whose gait may be different from that of blind walkers using a long cane or a dog guide. In this work, we show that a step length estimation network trained on data from sighted walkers performs poorly when tested on blind walkers, and that retraining with data from blind walkers can dramatically increase the accuracy of step length prediction.
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  • 文章类型: Journal Article
    当导航到一个地方时,学到了什么,这个问题一直是相当多的辩论的主题。流行观点强调认知结构(例如,地图)或联想学习,它在空间导航任务中形成了测量(例如,莫里斯水任务[MWT]),以选择不能捕获单个动物精确行为的粗略措施。我们在MWT中以高时间分辨率(30Hz)分析了15只大鼠(每次60次试验)的导航路径,并利用动态时间扭曲来量化动物内部和动物之间路径的相似性。道路基本上是直接的,然而次优,并包括在训练早期建立的每只动物特有的速度和轨迹的变化。从试验到试验,个体大鼠从相同的释放点执行相似的路径,这与其他大鼠执行的路径以及同一大鼠从其他释放点执行的路径不同。这些观察表明,对于MWT中的每个释放点,大鼠学习从试验到试验执行相似的路径序列。偶尔自发偏离既定的,独特的行为顺序,导致导航精度的严重中断。我们讨论了序列导航行为对理解行为与空间神经信号之间关系的潜在影响,例如位置细胞,网格单元格,和头部方向细胞。
    在线版本包含补充材料,可在10.1007/s40614-024-00402-8获得。
    The question of What is learned when navigating to a place is reinforced has been the subject of considerable debate. Prevailing views emphasize cognitive structures (e.g., maps) or associative learning, which has shaped measurement in spatial navigation tasks (e.g., the Morris water task [MWT]) toward selection of coarse measures that do not capture precise behaviors of individual animals. We analyzed the navigation paths of 15 rats (60 trials each) in the MWT at high temporal resolution (30Hz) and utilized dynamic time warping to quantify the similarity of paths within and between animals. Paths were largely direct, yet suboptimal, and included changes in speed and trajectory that were established early in training and unique to each animal. Individual rats executed similar paths from the same release point from trial to trial, which were distinct from paths executed by other rats as well as paths performed by the same rat from other release points. These observations suggest that rats learn to execute similar path sequences from trial to trial for each release point in the MWT. Occasional spontaneous deviations from the established, unique behavioral sequence, resulted in profound disruption in navigation accuracy. We discuss the potential implications of sequence navigation behaviors for understanding relations between behavior and spatial neural signals such as place cells, grid cells, and head direction cells.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s40614-024-00402-8.
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  • 文章类型: Journal Article
    海洋动物和跨洋鸟类的导航精度为使用地磁场(GMF)实现能够确定其在地球上的绝对位置的战略性真正自主水下航行器(AUV)提供了灵感。没有船舶参考声学基线系统的帮助。监督机器学习算法应用于从NOAA世界磁模型获得的GMF强度数据,在印度洋中部的印度矿物勘探区内900平方公里,分辨率为50米,考虑到商用磁力计的灵敏度。据确定,对于配备有检测灵敏度为0.1nT的磁力计的AUV,用先验GMF数据训练的监督随机森林回归和决策树算法,可以在2D平面中以绝对平均位置精度为AUV提供轨迹引导,参考最初使用GPS和水下声学定位辅助的组合导航系统的最后已知位置。圆形误差(CEP50)可能为53m和56m,分别。被证明是可行的GPS替代导航系统的标量GMF异常导航可以扩展到具有倾斜和倾斜矢量的更大区域,作为唯一标识符。
    The navigational accuracy of sea animals and trans-ocean birds provides inspiration in using geo-magnetic field (GMF) for realizing strategic truly autonomous underwater vehicles (AUV) capable of determining their absolute position on earth, without the aid of ship-referenced acoustic baseline systems. Supervised Machine Learning algorithms are applied on the GMF intensity data obtained from NOAA World Magnetic Model for a 900 km2 within the Indian mineral exploratory area in the Central Indian Ocean, with a resolution of 50 m, considering the sensitivity of commercially available magnetometers. It is identified that, for AUVs equipped with magnetometers with a detection sensitivity of 0.1 nT, the supervisory random forest regression and decision tree algorithm trained with priori GMF data, could provide trajectory guidance to AUVs with an absolute mean position accuracy in 2D plane, with reference to the last known position from Integrated Navigation system aided initially with GPS and with acoustic positioning in underwater. Circular Error Probable (CEP 50) of 53 m and 56 m, respectively. The scalar GMF anomaly navigation demonstrated to be a viable GPS-alternative navigation system could be extended to larger areas with inclination and declination vectors, as unique identifiers.
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  • 文章类型: Journal Article
    存在许多技术和技术用于组件定位的术中评估,腿长度,和全髋关节置换术的偏移,但比较数据有限。我们对现有文献进行了系统回顾,以评估术中评估组件位置以及腿长和偏移的准确性的技术和技术范围。精度,手术时间,成本,以及与临床结果的关系。
    对1974年至2023年的Embase和Medline数据库进行了全面搜索。我们纳入了对照或比较前瞻性临床研究。2名独立评审员使用Cochrane的随机试验偏倚风险工具和非随机研究中的偏倚风险-干预工具来评估每项研究的偏倚风险。我们对纳入的研究进行了定性和定量分析。然而,由于异质性,荟萃分析被认为不可行.
    我们的综述包括25项研究,其中52项术中技术和技术。在纳入的研究中,对机械指南和计算机导航进行了最频繁的评估。计算机导航系统在所有措施中始终显示出最高的准确性和精确度,以更长的平均手术时间为代价。相比之下,徒手技术表现出最差的准确性和精确度。在总体手术费用或临床结果的差异方面,发现数据不足,无法得出任何有意义的结论。
    证据表明,在全髋关节置换术中,计算机化的导航系统在定位组件方面最为准确和精确。需要进一步的研究来确定它们的健康和经济影响,以及导航技术的准确性和精确性在临床结果方面是否合理。
    UNASSIGNED: Many techniques and technologies exist for the intraoperative assessment of component positioning, leg lengths, and offset in total hip arthroplasty, but with limited comparative data. We conducted a systematic review of the available literature to evaluate the range of techniques and technologies for the intraoperative assessment of component position as well as leg lengths and offset in terms of accuracy, precision, surgical time, cost, and relationship to clinical outcomes.
    UNASSIGNED: A comprehensive search of the Embase and Medline databases from 1974 to 2023 was performed. We included controlled or comparative prospective clinical studies. Cochrane\'s risk-of-bias tool for randomized trials and Risk of Bias in Non-Randomized Studies - of Interventions tools were used by 2 independent reviewers to evaluate each study for risk of bias. We conducted both qualitative and quantitative analyses of the studies included. However, a meta-analysis was deemed not to be feasible due to heterogeneity.
    UNASSIGNED: Our review included 25 studies with 52 intraoperative techniques and technologies. Mechanical guides and computerized navigation were most frequently evaluated in the included studies. Computerized navigation systems consistently showed the greatest accuracy and precision across all measures, at the cost of longer mean operative time. In contrast, freehand techniques demonstrated the poorest accuracy and precision. Insufficient data were found to reach any meaningful conclusions in terms of differences in overall surgical cost or clinical outcomes.
    UNASSIGNED: Evidence shows that computerized navigation systems are most accurate and precise in positioning components during total hip arthroplasty. Further research is needed to determine their health and economic impact and whether the accuracy and precision of navigated techniques are justified in terms of clinical outcomes.
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  • 文章类型: Journal Article
    全膝关节置换术(TKA)是一种通常进行的手术,传统上使用一组机械器械进行可重复的步骤。使用机器人辅助执行的TKA数量正在增加,和增强现实(AR)导航系统正在开发中。分层任务分析(HTA)旨在详细描述特定任务的步骤,以减少错误并确保可重复性。这项研究的目的是开发和验证常规的HTAs,机器人辅助,和AR导航TKA。
    用于常规TKA的HTA的开发涉及一个迭代审查过程,该过程纳入了4名经验丰富的关节成形术外科医生的输入。然后,通过结合与使用这些系统相关的具体步骤,将HTA调整为机器人辅助和AR导航的TKA。通过观察10个常规和10个机器人辅助的TKA程序,验证了HTA的准确性和完整性。
    常规HTAs,机器人辅助,和AR导航的TKA被开发和验证。由此产生的HTA为每个程序提供了全面和标准化的计划,并有助于识别潜在的低效率和风险领域。机器人辅助和AR导航方法需要额外的步骤,并且可能发生并发症的情况越来越多。
    本研究中开发的HTA可以为机器人辅助和AR导航TKA程序的潜在陷阱提供有价值的见解。随着AR导航系统的发展,它们应该通过使用开发的HTA进行关键分析来优化,以确保最大的效率,可靠性,可访问性,减少人为错误,和成本。
    UNASSIGNED: Total knee arthroplasty (TKA) is a commonly performed procedure that has traditionally utilized reproducible steps using a set of mechanical instruments. The number of TKAs performed using robotic assistance is increasing, and augmented reality (AR) navigation systems are being developed. Hierarchical task analysis (HTA) aims to describe the steps of a specific task in detail to reduce errors and ensure reproducibility. The objective of this study was to develop and validate HTAs for conventional, robotic-assisted, and AR-navigated TKA.
    UNASSIGNED: The development of HTAs for conventional TKA involved an iterative review process that incorporated the input of 4 experienced arthroplasty surgeons. The HTAs were then adapted for robotic-assisted and AR-navigated TKA by incorporating specific steps associated with the use of these systems. The accuracy and completeness of the HTAs were validated by observing 10 conventional and 10 robotic-assisted TKA procedures.
    UNASSIGNED: HTAs for conventional, robotic-assisted, and AR-navigated TKA were developed and validated. The resulting HTAs provide a comprehensive and standardized plan for each procedure and can aid in the identification of potential areas of inefficiency and risk. Robotic-assisted and AR-navigated approaches require additional steps, and there are an increased number of instances where complications may occur.
    UNASSIGNED: The HTAs developed in this study can provide valuable insights into the potential pitfalls of robotic-assisted and AR-navigated TKA procedures. As AR-navigation systems are developed, they should be optimized by critical analysis using the developed HTAs to ensure maximum efficiency, reliability, accessibility, reduction of human error, and costs.
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  • 文章类型: Journal Article
    远程医疗的迅速增加有可能为高危人群带来人群水平的前列腺癌筛查(PCS)的知情决策。我们利用电子健康记录数据存储库(TriNetX)的全球技术平台来确定其在45-79岁无前列腺癌和PSA检测史的黑人男性中的导航指导决策辅助的实用性。来自宾夕法尼亚州的患者被邀请参加PCS的远程医疗提供的知情决策会议。焦点小组,社会学习理论,可视化图表,并使用PCS风险和收益的定量数据来制定会议的内容,其中包括对风险与风险的数字讨论黑人的好处。参与者完成了几项调查,包括基线人口统计和算术问卷,与训练有素的导航员进行一对一的远程医疗会议,导航后调查,以及与泌尿科医生的可选随访会议。87名参与者获得同意并被招募。尽管平均算术分数仅为6分的1.9分,但超过90%的人认为会议有助于他们的PCS决策技能。这项研究表明,通过远程医疗导航提供了在人口水平上协助PCS做出明智决策的能力。
    The rapid increase in telehealth has the potential to bring informed decision-making for prostate cancer screening (PCS) at the population level to high-risk individuals. We utilized a global technology platform of electronic health records data repositories (TriNetX) to determine its utility for Navigator-guided decision-making aid for PCS in Black men ages 45-79 years with no history of prostate cancer and PSA testing. Patients from Pennsylvania were invited to participate in a telehealth-delivered informed decision-making session for PCS. Focus groups, social learning theory, visual diagrams, and quantitative data on PCS risks and benefits were used to develop the content of the sessions, which included numerical discussions of risks vs. benefits in Black men. Participants completed several surveys, including baseline demographic and numeracy questionnaires, a one-on-one telehealth session with a trained Navigator, post-Navigation surveys, and an optional follow-up session with a urologist. Eighty-seven participants were consented and recruited. Although the mean numeracy score was only 1.9 out of 6, more than 90% rated as good or excellent that the sessions aided their PCS decision-making skills. This study indicates that Navigation by telehealth offers the ability to assist in informed decision-making for PCS at the population level.
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  • 文章类型: Journal Article
    昆虫依靠路径集成(基于矢量的导航)和地标指导来执行复杂的导航壮举,与哺乳动物中看到的相媲美。特别是蜜蜂表现出复杂的导航行为,包括在位置之间创建最佳路线和新颖的快捷方式,一种历史上表明认知地图存在的能力。哺乳动物认知图已被广泛接受。然而,在昆虫中,集中的认知地图的存在是非常有争议的。使用受控的实验室测定法,将行走的大黄蜂的觅食行为浓缩到短距离,我们发现在路径整合过程中学习的向量可以转移到长期记忆中,多个这样的向量可以并行存储,这些向量可以在熟悉的位置被召回并用于回家导航。这些发现表明,蜜蜂满足分散认知图的基于矢量的模拟的两个基本要求:家庭矢量需要存储在长期记忆中,并且需要从记住的位置召回。因此,我们的数据表明,蜜蜂拥有基于矢量的地图的基本要素。通过利用这种相对简单的空间组织策略,昆虫可能会在大脑中神经元数量有限的脊椎动物中实现高级导航行为,规避与哺乳动物认知图相关的计算需求。
    Insects rely on path integration (vector-based navigation) and landmark guidance to perform sophisticated navigational feats, rivaling those seen in mammals. Bees in particular exhibit complex navigation behaviors including creating optimal routes and novel shortcuts between locations, an ability historically indicative of the presence of a cognitive map. A mammalian cognitive map has been widely accepted. However, in insects, the existence of a centralized cognitive map is highly contentious. Using a controlled laboratory assay that condenses foraging behaviors to short distances in walking bumblebees, we reveal that vectors learned during path integration can be transferred to long-term memory, that multiple such vectors can be stored in parallel, and that these vectors can be recalled at a familiar location and used for homeward navigation. These findings demonstrate that bees meet the two fundamental requirements of a vector-based analog of a decentralized cognitive map: Home vectors need to be stored in long-term memory and need to be recalled from remembered locations. Thus, our data demonstrate that bees possess the foundational elements for a vector-based map. By utilizing this relatively simple strategy for spatial organization, insects may achieve high-level navigation behaviors seen in vertebrates with the limited number of neurons in their brains, circumventing the computational requirements associated with the cognitive maps of mammals.
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