背景:宫颈癌与人乳头瘤病毒(HPV)感染密切相关。在这项回顾性研究中,我们分析了2019-2021年在南京市第一医院进行HPV检测的绝经后妇女的资料.
方法:我们回顾性分析了14608名年龄在45-90岁之间的绝经后妇女的资料。2019年1月至2021年12月在南京第一医院接受HPV检查。所有参与者都接受了23种HPV基因型的检测。我们随后分析了感染率,并使用卡方检验评估了HPV的分布。
结果:我们的结果表明,南京地区绝经后妇女的HPV感染率,中国为22.36%。从年龄组来看,感染率为19.54%,24.30%,26.58%,在≤50、51-60、61-70和≥71岁的人群中,为14.99%,分别。最常见的HPV亚型是HPV52(22.1-3%),HPV58(15.86%),HPV53(14.17%),HPV16(12.61%),和HPV81(11.66%),按这个顺序。单一HPV感染率为14.23%,多基因型感染率为8.14%(1189/14,608)。
结论:这项研究表明,在南京,中国,不同年龄段的绝经后妇女可能有不同的HPV感染率,最常见的类型是HPV52、HPV58、HPV53、HPV16和HPV81。这些发现强调了了解特定人群中HPV感染流行病学的重要性。比如南京的绝经后妇女,中国。研究结果可以为医疗保健专业人员和政策制定者提供有价值的信息,以制定有针对性的预防和筛查策略,以减轻该人群中HPV相关疾病的负担。
Cervical cancer is strongly associated with human papillomavirus (HPV) infection. In this retrospective study, we analyzed the data of postmenopausal women who were tested for HPV in Nanjing First Hospital from 2019 to 2021.
We retrospectively analyzed the data of 14,608 postmenopausal women aged 45-90 years, who underwent HPV examination in Nanjing First Hospital between January 2019 and December 2021. All participants were tested for 23 HPV
genotypes. We subsequently analyzed the infection rate and evaluated the distribution of HPV using the chi-square test.
Our results showed that the HPV infection rate in postmenopausal women in Nanjing,
China was 22.36%. In terms of age group, the infection rate was 19.54%, 24.30%, 26.58%, and 14.99% in those aged ≤ 50, 51-60, 61-70, and ≥ 71 years, respectively. The most common HPV subtypes were HPV52 (22.1 3%), HPV58 (15.86%), HPV53 (14.17%), HPV16 (12.61%), and HPV81 (11.66%), in that order. The single-HPV infection rate was 14.23%, and the multiple-genotype infection rate was 8.14% (1189/14,608).
This study showed that in Nanjing,
China, the different age groups of post-menopausal women could have different rates of HPV infection, and the most common types were HPV52, HPV58, HPV53, HPV16 and HPV81. These findings highlighted the importance of understanding the epidemiology of HPV infection in specific populations, such as postmenopausal women in Nanjing,
China. The results could provide valuable information for healthcare professionals and policymakers to develop targeted prevention and screening strategies for reducing the burden of HPV-related diseases in this population.