未经证实:父母吸烟是儿科人群被动吸烟的主要来源。目前的随机对照试验(RCT)研究旨在评估多组分减少吸烟干预在减少父母吸烟和减少儿童环境烟草烟雾暴露中的临床设置的有效性。
未经评估:单盲,为期6个月的随机对照试验招募了在威尔士亲王医院儿科病房或诊所就诊的吸烟儿童父母(N=210)。分配到干预组的参与者(n=105)每月接受关于减少吸烟的动机访谈,重点是与儿童被动吸烟相关的健康危害。8周尼古丁替代疗法,如果父母愿意,则转介戒烟服务。对照组(n=105)接受简单的口头戒烟建议。主要结果为父母尿液可替宁验证和自我报告6个月时吸烟减少率≥50%。
UNASSIGNED:干预组的吸烟父母在生化方面验证的吸烟减少≥50%明显高于对照组:27.1vs.10.0%(OR=3.34,95%CI:1.16~9.62,P=0.02)。干预组自我报告的吸烟减少率≥50%也显着高于对照组:51.9vs.20.2%(OR=4.40,95%CI:2.38~8.12,P<0.001)。对于次要结果,干预组的父母自我报告戒烟率较高:10.5vs.1.0%(OR=12.17,95%CI:1.54-96.07,P<0.001),然而,在经生化检验的戒烟和儿童被动烟雾暴露变化方面,两组间未发现差异.
UNASSIGNED:每月减少吸烟咨询与尼古丁替代疗法在减少儿科患者父母的吸烟方面比简单的口头戒烟建议更有效。然而,这项研究在6个月的随访中没有发现戒烟或减少儿童被动吸烟暴露的差异.实现无烟环境仍然具有挑战性。
未经评估:Clinicaltrials.gov,标识符:NCT03879889。
UNASSIGNED: Parental smoking is the dominant source of passive smoke exposure in the pediatric population. The current randomized controlled trial (RCT) study aimed to evaluate the effectiveness of a multi-component smoking reduction intervention in parental smoking reduction and children\'s environmental tobacco smoke exposure reduction in clinical settings.
UNASSIGNED: A single-blinded, 6-month randomized controlled trial recruited smoking parents (N = 210) of children who attended the pediatric wards or clinics at the Prince of Wales Hospital. Participants allocated to the intervention group (n = 105) received monthly motivational interviews on smoking reduction with emphasis on health hazards related to children\'s passive smoke exposure, 8-week nicotine replacement therapy, and referral to smoking cessation service if the parents preferred. The control group (n = 105) received simple verbal advice on smoking cessation. Primary outcomes were parental urine cotinine validated and self-reported ≥50% smoking reduction rates at 6 months.
UNASSIGNED: Smoking parents in the intervention group had significantly more biochemically validated ≥50% smoking reduction than the control: 27.1 vs. 10.0% (OR = 3.34, 95% CI: 1.16-9.62, P = 0.02). The rate of self-reported ≥50% smoking reduction was also significantly higher in the intervention group than the control: 51.9 vs. 20.2% (OR = 4.40, 95% CI: 2.38-8.12, P < 0.001). For secondary outcomes, the rate of parental self-reported smoking cessation was higher in the intervention arm: 10.5 vs. 1.0% (OR = 12.17, 95% CI: 1.54-96.07, P < 0.001), however, no differences were detected in biochemically validated cessation and changes in children\'s passive smoke exposure between the groups.
UNASSIGNED: Monthly smoking reduction counseling together with nicotine replacement therapy is more effective than simple verbal cessation advice in the smoking reduction for parents of pediatric patients. However, this study did not demonstrate differences in smoking cessation or reduction in children\'s passive smoke exposure with a 6-month follow-up. Achievement of a smoke-free environment remains challenging.
UNASSIGNED: Clinicaltrials.gov, identifier: NCT03879889.