Natural dyes have been used for centuries for coloring textiles, food, and other materials. Synthetic dyes are particularly popular due to their ease of use, wide range of available colors, and fastness. However, their usage comes with significant environmental and health challenges. In recent years, there has been a renewed interest in natural dyes due to their eco-friendliness, ready availability, affordability, non-toxicity, and sustainability. Hence, natural dyes are fast gaining popularity as better alternatives to synthetic dyes. Nature is blessed with a rich diversity of plant species with varying colors and properties which can be harnessed in textile, printing, cosmetics, and food industries. This paper presents a comprehensive review on natural and synthetic dyes with particular focus on their history, properties, classification, extraction methods, applications, and health challenges. Although many plants have been suggested as potential sources of natural dyes, there is insufficient information on their exploration and application. Additionally, chemical analyses of these dyes have not been extensively done. Overall, the results of studies conducted so far identified a number of promising taxa for further investigation as plant-based dyes with many indigenous plants as potential sources of natural dyes.

Organophosphate esters (OPEs), which are phosphoric acid ester derivatives, are anthropogenic substances that are widely used in commerce. Nevertheless, there is growing public concern about these ubiquitous contaminants, which are frequently detected in contaminated water sources. OPEs are mostly emitted by industrial operations, and the primary routes of human exposure to OPEs include food intake and dermal absorption. Because of their negative effects on both human health and the environment, it is clear that innovative methods are needed to facilitate their eradication. In this study, we present a comprehensive overview of the existing characteristics and origins of OPEs, their possible impacts on human health, and the merits, drawbacks, and future possibilities of contemporary sophisticated remediation methods. Current advanced remediation approaches for OPEs include adsorption, degradation (advanced oxidation, advanced reduction, and redox technology), membrane filtration, and municipal wastewater treatment plants, degradation and adsorption are the most promising removal technologies. Meanwhile, we proposed potential areas for future research (appropriate management approaches, exploring the combination treatment process, economic factors, and potential for secondary pollution). Collectively, this work gives a comprehensive understanding of OPEs, providing useful insights for future research on OPEs pollution.

Agro-based pulp and paper mills (PPMs) inevitably produce numerous refractory pollutants in their wastewater, including chlorolignin, chlorophenols, chlorocatechols, chloroguaiacol, cyanide, furan, dioxins, and other organic compounds, as well as various heavy metals, such as nickel (Ni), zinc (Zn), chromium (Cr), iron (Fe), lead (Pb), arsenic (As), etc. These pollutants pose significant threats to aquatic and terrestrial life due to their cytogenotoxicity, mutagenicity, impact on sexual organs, hormonal interference, endocrine disruption, and allergenic response. Consequently, it is crucial to reclaim pulp paper mill wastewater (PPMW) with high loads of refractory pollutants through effective and environmentally sustainable practices to minimize the presence of these chemicals and ensure environmental safety. However, there is currently no comprehensive published review providing up-to-date knowledge on the fate of refractory pollutants from PPMW in soil and aquatic environments, along with valuable insights into the associated health hazards and remediation methods. This critical review aims to shed light on the potential adverse effects of refractory pollutants from PPMW on natural ecosystems and living organisms. It explores existing effective treatment technologies for remediating these pollutants from wastewater, highlighting the advantages and disadvantages of each approach, all in pursuit of environmental safety. Special emphasis is placed on emerging technologies used to decontaminate wastewater discharged from PPMs, ensuring the preservation of the environment. Additionally, this review addresses the major challenges and proposes future research directions for the proper disposal of PPMW. It serves as a comprehensive source of knowledge on the environmental toxicity and risks associated with refractory pollutants in PPMW, making it a valuable reference for policymakers and researchers when selecting appropriate technologies for remediation. The scientific community, concerned with mitigating the widespread risks posed by refractory pollutants from PPMs, is expected to take a keen interest in this review.

Histamine (HIS) intoxication is a poisoning caused by histamine in food. Cheese is one of the most common dairy products associated with histamine levels which vary depending on the processing methods. The final content of histamine in cheese is influenced by intrinsic and extrinsic factors, their interactions, and contamination stemming from food processing. The application of control measures may be useful to inhibit/reduce production during cheese manufacture and processing but have a limited effect. To reduce histamine intoxication outbreaks from cheese consumption the introduction of quality control programs and appropriate risk mitigation options should be applied along the dairy chain from an overall perspective of food safety based on individual susceptibility and consumer sensitivity. As key food safety, this topic should be considered in future regulations in dairy products because the lack of a clear law on HIS limits in cheese may result in a significant potential deviation from the EU food safety strategy.

OBJECTIVE: Over 50 countries are affected by arsenic contamination. The problem is becoming worse as the number of affected people increases and new sites are reported globally.
BACKGROUND: Various human activities have increased arsenic pollution, notably in both terrestrial and aquatic environments. Contamination of our water and soil by arsenic poses a threat to our environment and natural resources. Arsenic poisoning harms several physiological systems and may cause cancer and death. Excessive exposure may cause toxic build-up in human and animal tissues. Arsenic-exposed people had different skin lesion shapes and were vulnerable to extra arsenic-induced illness risks. So far, research shows that varying susceptibility plays a role in arsenic-induced diseases. Several studies have revealed that arsenic is a toxin that reduces metabolic activities. Diverse remediation approaches are being developed to control arsenic in surrounding environments.
UNASSIGNED: A sustainable clean-up technique (nanoremediation) is required to restore natural equilibrium. More research is therefore required to better understand the biogeochemical processes involved in removing arsenic from soils and waters.

Irrational use of antibiotics produces a large number of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs). Wastewater treatment plants (WWTPs) act as important sources and sinks of ARGs, and play an important role in their generation, treatment, and dissemination. This study summarizes the types, concentrations, and factors of ARGs in WWTPs, investigates the sources of ARGs in wastewater, compares the removal efficiencies of different treatment processes on ARGs, and analyzes the potential risks of ARGs accumulation in effluent, sludge and their emission into the air. The results show that the main ARGs detected in the influent of WWTPs are the genes resistant to macrolides (ermB, ermF), tetracyclines (tetW, tetA, tetC), sulfonamides (sul1, sul2), and β-lactams (blaOXA, blaTEM). The concentrations of ARGs in the influent of the WWTPs are 2.23 × 102-3.90 × 109 copies/mL. Wastewater quality and microbial community are the dominant factors that affect the distribution characteristics of ARGs. The accumulation of ARGs in effluent, sludge, and aerosols pose potential risks to the regional ecological environment and human health. Based on these results, research trends with respect to ARGs in WWTPs are also prospected.

Electronic waste (e-waste) contains a variety of electronic components e.g., metals, non-metals, plastics, cables, etc. The excessive generation of e-waste has become a significant concern in the last few decades. The current global e-waste generation is 57.4 million metric tons (MMT) per year. Asia produces the highest amount of e-waste (24.9 MMT) followed by America, Europe, Africa, and Oceania. In Bangladesh, e-waste produces from two sources: its own consumption of electronic devices, which is 0.6 MMT, and imported e-waste from ship breaking yards that is 2.5 MMT in 2021. However, inadequate information on the current state of e-waste generation and management systems in Bangladesh has created a void to establish the future direction for proper handling of e-waste. In this work, the Bangladesh perspective of e-waste has been analyzed. The environmental, health economical forfeiture of e-waste has been discussed. The development of government legislations regarding e-waste have been stated. The establishment of e-waste management has been designed by the life cycle assessment (LCA) and material flow analysis (MFA) models. Moreover, a holistic approach for understanding the possible hazards, the economic feasibility of e-waste processing and viable management models for e-waste in Bangladesh was endeavored in this work to propose systematic future directions and recommendations to improve the current e-waste scenario of Bangladesh.

Single-use plastics (SUPs) have become an essential constituent of our daily life. It is being exploited in numerous pharmaceutical and healthcare applications. Despite their advantages and widespread use in the pharma and medical sectors, the potential clinical problems of plastics, especially the release of micro-nanoplastics (MNPs) and additives from medical plastics (e.g. bags, containers, and administrative sets) and sorption of drugs remain understudied. Certainly, the MNPs are multifaceted stressors that cause detrimental effects to the ecosystem and human health. The origin and persistence of MNPs in pharmaceutical products, their administration to humans, endurance and possible health implication, translocation, and excretion have not been reviewed in detail. The prime focus of this article is to conduct a systematic review on the leaching of MNPs and additives from pharmaceutical containers/administrative sets and their interaction with the pharmaceutical constituents. This review also explores the primary and secondary routes of MNPs entry from healthcare plastic products and their potential health hazards to humans. Furthermore, the fate of plastic waste generated in hospitals, their disposal, and associated MNPs release to the environment, along with preventive, and alternative measures are discussed herein.

Living beings have been devastated by environmental pollution, which has reached its peak. The disastrous pollution of the environment is in large part due to industrial wastes containing toxic pollutants. The widespread use of chromium (Cr (III)/Cr (VI)) in industries, especially tanneries, makes it one of the most dangerous environmental pollutants. Chromium pollution is widespread due to ineffective treatment methods. Bioremediation of chromium (Cr) using bacteria is very thoughtful due to its eco-friendly and cost-effective outcome. In order to counter chromium toxicity, bacteria have numerous mechanisms, such as the ability to absorb, reduce, efflux, or accumulate the metal. In this review article, we focused on chromium toxicity on human and environmental health as well as its bioremediation mechanism.

Nanotechnology has the potential to generate advancements and innovations in formulations and delivery systems. This fast-developing technology has been widely exploited for diagnostic and therapeutic purposes. Today, cosmetic formulations incorporating nanotechnology are a relatively new yet very promising and highly researched area. The application of nanotechnology in cosmetics has been shown to overcome the drawbacks associated with traditional cosmetics and also to add more useful features to a formulation. Nanocosmetics and nanocosmeceuticals have been extensively explored for skin, hair, nails, lips, and teeth, and the inclusion of nanomaterials has been found to improve product efficacy and consumer satisfaction. This is leading to the replacement of many traditional cosmeceuticals with nanocosmeceuticals. However, nanotoxicological studies on nanocosmeceuticals have raised concerns in terms of health hazards due to their potential skin penetration, resulting in toxic effects. This review summarizes various nanotechnology-based approaches being utilized in the delivery of cosmetics as well as cosmeceutical products, along with relevant patents. It outlines their benefits, as well as potential health and environmental risks. Further, it highlights the regulatory status of cosmeceuticals and analyzes the different regulatory guidelines in India, Europe, and the USA and discusses the different guidelines and recommendations issued by various regulatory authorities. Finally, this article seeks to provide an overview of nanocosmetics and nanocosmeceuticals and their applications in cosmetic industries, which may help consumers and regulators to gain awareness about the benefits as well as the toxicity related to the continuous and long-term uses of these products, thus encouraging their judicious use.