Longitudinal study

纵向研究
  • 文章类型: Journal Article
    青春期是对未来做出重要决定的时候,对心理健康问题的脆弱性增加。我们回顾了纵向研究,研究了与未来相关的思维(绝望,希望,乐观/积极的未来期望)和青少年抑郁和焦虑症状。来自22项研究(N=10,682)的证据发现,与未来相关的负面思维可以预测随后的抑郁(r=0.27,p<.001),在控制基线抑郁后,效果仍然显著(r=0.23,p<.001)。更高的绝望(r=0.34,p<.001),较低的希望(r=0.16,p<.001),和降低的乐观/积极的未来预期(r=0.18,p<.001)与随后增加的抑郁症状相关。消极的未来相关思维也预测了后来焦虑症状的增加(r=0.15,p=.021)。关于互惠途径,抑郁症状与后来的负面未来相关思维有关(r=0.32,p<.001),在未来相关思维的基线水平得到控制后仍然存在(r=0.07,p=.02).没有足够的研究来推断焦虑和未来相关思维之间的相互联系。我们的分析提供了抑郁症状与未来相关思维之间相互发展关系的证据,意味着一个负周期。确定这一周期的前兆可以为青少年抑郁症的预防提供基础,并促进对未来的更好决策。
    Adolescence is a time when important decisions about the future are made and vulnerability to mental health problems increases. We reviewed longitudinal studies examining the reciprocal pathways between future-related thinking (hopelessness, hope, optimism/positive future expectations) and adolescent depression and anxiety symptoms. Evidence from 22 studies (N = 10,682) found that negative future-related thinking predicted subsequent depression (r = 0.27, p < .001), an effect still significant after controlling for baseline depression (r = 0.23, p < .001). Higher hopelessness (r = 0.34, p < .001), lower hope (r = 0.16, p < .001), and reduced optimism/positive future expectations (r = 0.18, p < .001) were associated with subsequently increased depressive symptoms. Negative future-related thinking also predicted later increased anxiety symptoms (r = 0.15, p = .021). Concerning the reciprocal pathway, depressive symptoms were associated with later negative future-related thinking (r = 0.32, p < .001), which remained after baseline levels of future-related thinking were controlled (r = 0.07, p = .02). There were insufficient studies to infer reciprocal links between anxiety and future-related thinking. Our analyses provided evidence of a reciprocal developmental relationship between depressive symptoms and future-related thinking, implying a negative cycle. Identifying precursors of this cycle could provide the basis for depression prevention in adolescents and promote better decision-making about the future.
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  • 文章类型: Journal Article
    患有自闭症谱系障碍(ASD)诊断的个体显示执行功能(EF)受损。然而,关于自闭症个体和具有典型发育(TD)的人之间年龄对EF的影响差异的发现是混合的。关于ASD中EF的年龄相关轨迹是否与TD中的相同或不同,仍然存在疑问。为了弥合这种知识差距,我们对纵向研究进行了系统综述和荟萃分析,比较了ASD组和TD组之间与年龄相关的EF变化(预注册:osf.io/j5764).使用PubMed进行了文献检索,PsycINFO,和WebofScience于2024年1月29日发布。经过两位独立审稿人的筛选,包括14项纵向研究。对总共涉及518名自闭症患者和3558名TD儿童和青少年(平均基线年龄:5.7-12.0岁)的研究进行的随机效应荟萃分析显示,ASD在基线和随访时的EF均明显低于TD。然而,不同领域的EF与年龄相关的变化没有显著的组间差异,包括工作记忆,抑制,shifting,和规划。稳健的贝叶斯荟萃分析也提供了支持零假设的大量证据,即ASD和TD组在大多数EF过程中随着时间的推移显示出相似的变化。文献的局限性包括有限的纵向研究和狭窄的发育阶段范围以及跨研究分析的EF结构。总之,这些研究结果表明,自闭症儿童和青少年的EF通常可以随着时间的推移而改善,与他们的神经典型同龄人相似.这对家长和教育工作者具有重要意义,鼓励在早期阶段对自闭症儿童和青少年进行适当的EF培训和干预。
    Individuals with an autism spectrum disorder (ASD) diagnosis show impairment in executive function (EF). However, findings are mixed regarding differences in the age effect on EF between autistic individuals and persons with typical development (TD). Questions remain regarding whether the age-related trajectories of EF in ASD are the same as or different from those in TD. To bridge this knowledge gap, we conducted a systematic review and meta-analyses of longitudinal studies that compared age-related changes in EF between ASD and TD groups (preregistration: osf.io/j5764). A literature search was conducted using PubMed, PsycINFO, and Web of Science on January 29, 2024. After screening by two independent reviewers, 14 longitudinal studies were included. Random-effects meta-analyses of studies involving a maximum total of 518 autistic and 3558 TD children and adolescents (mean baseline ages: 5.7-12.0 years) showed that ASD had significantly poorer EF than TD at both baseline and follow-up. However, there was no significant group difference in the age-related change in EF across domains, including working memory, inhibition, shifting, and planning. Robust Bayesian meta-analyses also provided substantial evidence in favor of the null hypothesis that ASD and TD groups showed similar changes over time for most EF processes. Limitations of the literature included the limited number of longitudinal studies and a narrow range of developmental stages and EF constructs analyzed across studies. Altogether, these findings suggest that autistic children and adolescents generally can improve in EF over time similarly to their neurotypical peers. This has important implications for parents and educators, encouraging appropriate EF training and intervention for autistic children and adolescents at an early stage.
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  • 文章类型: Journal Article
    牙周炎和炎症性肠病(IBD)与时间方向性之间的双向关联仍然没有定论。本研究旨在通过系统评价和荟萃分析评估牙周炎和IBD之间的双向关联。五个数据库(PubMed,Embase,WebofScience,Scopus和Cochrane图书馆)从开始到2024年2月27日进行了系统搜索。两名独立审稿人对检索到的研究进行了审查。纵向研究,包括队列和嵌套病例对照研究,被认为符合研究设计的条件。荟萃分析得出的合并风险比(RR)和风险比(HR)用于评估牙周炎(或IBD)是否是IBD(或牙周炎)的危险因素。进行试验序贯分析(TSA)以评估结果的可靠性。纳入了四项关于牙周炎患者IBD风险的研究(n=10270912)和两项关于IBD患者牙周炎风险的研究(n=33420)。结果表明,牙周炎不会增加IBD的风险(合并RR=1.04,95%置信区间[CI]:0.99-1.09;p=.164;I平方统计量[I2]=27%)。对于IBD的亚型,牙周炎与溃疡性结肠炎(UC)的发生有关(合并RR=1.12,95%CI:1.04-1.21;p=.003;I2=38%),但不与克罗恩病(CD)(合并RR=0.98,95%CI:0.92-1.04;p=.475;I2=0%)。具体来说,患有牙周炎的男性(合并HR=1.11,95%CI:1.01~1.22;p=.025;I2=0%)和吸烟者(合并HR=1.23,95%CI:1.07~1.42;p=.004;I2=0%)患UC的风险高于无牙周炎的男性.IBD患者患牙周炎的风险较高(合并HR=1.37,95%CI:1.26-1.49;p<.001;I2=18%);然而,IBD亚型是否增加牙周炎的发生仍不确定。TSA结果证实了主要发现的可靠性。基于有限的纵向证据,牙周炎患者总体发展为IBD的风险并未增加,但他们患UC(非CD)的风险增加。相反,随着时间的推移,IBD患者患牙周炎的风险更高.需要更多高质量的纵向研究来确定IBD的特定亚型对牙周炎的影响。
    The bidirectional associations between periodontitis and inflammatory bowel disease (IBD) with temporal directionality remain inconclusive. This study aims to evaluate the bidirectional associations between periodontitis and IBD through a systematic review and meta-analysis. Five databases (PubMed, Embase, Web of Science, Scopus and Cochrane Library) were systematically searched from inception to 27 February 2024. Two independent reviewers performed a review of the retrieved studies. Longitudinal studies, including cohort and nested case-control studies, were considered eligible for the study design. The pooled risk ratio (RR) and hazard ratio (HR) derived from the meta-analysis were used to assess whether periodontitis (or IBD) was a risk factor for IBD (or periodontitis). Trial sequential analysis (TSA) was performed to evaluate the reliability of the results. Four studies (n = 10 270 912) on the risk of IBD in patients with periodontitis and two (n = 33 420) on the risk of periodontitis in patients with IBD were included. The result suggested that periodontitis did not increase the risk of IBD (pooled RR = 1.04, 95% confidence interval [CI]: 0.99-1.09; p = .164; I-squared statistic [I2] = 27%). For subtypes of IBD, periodontitis was associated with the occurrence of ulcerative colitis (UC) (pooled RR = 1.12, 95% CI: 1.04-1.21; p = .003; I2 = 38%), but not with Crohn\'s disease (CD) (pooled RR = 0.98, 95% CI: 0.92-1.04; p = .475; I2 = 0%). Specifically, the risk of UC was higher among men (pooled HR = 1.11, 95% CI: 1.01-1.22; p = .025; I2 = 0%) and smokers (pooled HR = 1.23, 95% CI: 1.07-1.42; p = .004; I2 = 0%) with periodontitis than their counterparts without periodontitis. Patients with IBD may have a higher risk of developing periodontitis (pooled HR = 1.37, 95% CI: 1.26-1.49; p < .001; I2 = 18%); however, whether IBD subtypes increased the occurrence of periodontitis remained uncertain. The TSA results confirmed the reliability of the primary findings. Based on limited longitudinal evidence, patients with periodontitis do not exhibit an increased risk of developing IBD overall, but they are at increased risk of UC (not CD). On the contrary, patients with IBD have a higher risk of developing periodontitis over time. More high-quality longitudinal studies are needed to determine the effect of specific subtypes of IBD on periodontitis.
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  • 文章类型: Journal Article
    目标:综合纵向研究评估邻里环境和认知,以确定方法论方法,调查结果,和差距。方法:纳入的研究纵向评估了生活在发达国家的>45岁(或平均年龄65岁)的成年人之间的邻里和认知之间的关联。我们提取了样本特征的数据,暴露,结果,方法,总体调查结果,以及对差异的评估。结果:40项研究符合我们的纳入标准。大多数(65%)仅测量一次暴露,大多数集中在绿色空间和/或蓝色空间(水),邻里社会经济地位,和娱乐/体育活动设施。同样,超过一半的研究事件损害,认知功能或下降(70%),其中一项检查MRI(2.5%)或阿尔茨海默病(7.5%)。虽然大多数研究使用重复测量分析来评估大脑健康结果的变化(51%),许多研究没有考虑社区内任何类型的相关性(35%).按种族/民族评估的效果修改不到一半,社会经济地位,和/或性别/性别。证据参差不齐,取决于暴露或评估的结果。结论:尽管评估邻域和认知衰退的纵向研究已经扩大,暴露类型仍然存在差距,结果,分析方法,和样本多样性。
    Objective: Synthesize longitudinal research evaluating neighborhood environments and cognition to identify methodological approaches, findings, and gaps. Methods: Included studies evaluated associations between neighborhood and cognition longitudinally among adults >45 years (or mean age of 65 years) living in developed nations. We extracted data on sample characteristics, exposures, outcomes, methods, overall findings, and assessment of disparities. Results: Forty studies met our inclusion criteria. Most (65%) measured exposure only once and a majority focused on green space and/or blue space (water), neighborhood socioeconomic status, and recreation/physical activity facilities. Similarly, over half studied incident impairment, cognitive function or decline (70%), with one examining MRI (2.5%) or Alzheimer\'s disease (7.5%). While most studies used repeated measures analysis to evaluate changes in the brain health outcome (51%), many studies did not account for any type of correlation within neighborhoods (35%). Less than half evaluated effect modification by race/ethnicity, socioeconomic status, and/or sex/gender. Evidence was mixed and dependent on exposure or outcome assessed. Conclusion: Although longitudinal research evaluating neighborhood and cognitive decline has expanded, gaps remain in types of exposures, outcomes, analytic approaches, and sample diversity.
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  • 文章类型: Systematic Review
    背景:成功招募男性参与者完成医疗保健相关研究对于完成医疗保健研究和推进我们的临床知识库非常重要。迄今为止,大多数研究研究都检查了纵向医疗保健相关研究中女性参与者的障碍和促进因素,但纵向研究中男性需求的信息有限。本系统综述研究了纵向医疗保健相关研究中男性招募的独特障碍和促进因素。
    方法:遵循PRIMSA指南,MEDLINE,Embase,CINAHL和WebofScience数据库使用术语招聘和/或保留进行了系统搜索,促进因素和/或障碍以及1900年至2023年的纵向研究,其中包含有关17-59岁男性的单独数据。如果健康研究或干预措施的持续时间大于或等于12周,并进行3次单独的数据收集访问,则将其定义为纵向。
    结果:1976-2023年发表的二十四篇文章符合标准。三分之一的研究主要是男性样本,四项研究仅招募男性参与者。男性似乎对参与健康研究不感兴趣,然而,这种缺乏热情是可以克服的,非指令通信,以及支持参与者兴趣的研究。促进因素是多种多样的,可能需要研究团队花费大量时间。
    结论:未来的研究应该关注这些因素在纵向健康相关研究中的具体影响。根据本系统综述的结果,我们鼓励来自纵向健康相关临床试验的研究人员考虑针对男性的招募策略,以确保他们的研究成功招募和保留.
    背景:本系统综述已在PROSPERO数据库(CRD42021254696)中注册。
    BACKGROUND: Successfully recruiting male participants to complete a healthcare related study is important for healthcare study completion and to advance our clinical knowledgebase. To date, most research studies have examined the barriers and facilitators of female participants in longitudinal healthcare-related studies with limited information available about the needs of males in longitudinal research. This systematic review examines the unique barriers and facilitators to male recruitment across longitudinal healthcare-related research studies.
    METHODS: Following PRIMSA guidelines, MEDLINE, Embase, CINAHL and Web of Science databases were systematically searched using the terms recruitment and/or retention, facilitators and/or barriers and longitudinal studies from 1900 to 2023 which contained separate data on males aged 17-59 years. Health studies or interventions were defined longitudinal if they were greater than or equal to 12 weeks in duration with 3 separate data collection visits.
    RESULTS: Twenty-four articles published from 1976-2023 met the criteria. One-third of the studies had a predominantly male sample and four studies recruited only male participants. Males appear disinterested towards participation in health research, however this lack of enthusiasm can be overcome by clear, non-directive communication, and studies that support the participants interests. Facilitating factors are diverse and may require substantial time from research teams.
    CONCLUSIONS: Future research should focus on the specific impact of these factors across the spectrum of longitudinal health-related studies. Based on the findings of this systematic review, researchers from longitudinal health-related clinical trials are encouraged to consider male-specific recruitment strategies to ensure successful recruitment and retention in their studies.
    BACKGROUND: This systemic review is registered with the PROSPERO database (CRD42021254696).
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  • 文章类型: Systematic Review
    前瞻性纵向研究主要得出以下结论:电子烟在卷烟启动过程中的因果作用与流行病学和其他研究得出的结论明显矛盾,表明卷烟使用量急剧下降与电子烟使用的传播并行。本系统综述探讨了这种差异的原因。
    方法:在2011年至2022年Medline数据库中确定的84篇有关青少年电子烟/香烟协会的出版物中,有23篇涉及22个从不吸烟者纵向子队列。
    结果:在不吸烟者(AOR:1.41至8.30)的子队列分析中报告了T1时电子烟实验与T2时香烟开始之间的联系。然而,研究排除了64.3%的T1电子烟实验者(由于双重用途)和74.1%的T2电子烟实验者。通过这项研究设计,电子烟仅占T2卷烟实验的5.3%,对结果和作者的结论的外部有效性提出了重大怀疑,即电子烟在人群水平上对卷烟的启动(Gateway效应)有重大影响。此子队列设计禁止突出任何分流效应,这是解释这两种产品之间竞争的最有可能的机制。
    结论:虽然戒烟仍然是最好的医疗选择,由于对纵向研究结果的误解而导致的电子烟的过度监管可能不利于公共卫生和烟草控制。
    Prospective longitudinal studies mainly conclude on a causal role of e-cigarettes in the initiation of cigarettes in flagrant contradiction with conclusions drawn from epidemiology and other studies showing a sharp decline in cigarette use in parallel with the spread of e-cigarette use. This systematic review explores the reasons for this discrepancy.
    Among 84 publications on e-cigarette/cigarette association in adolescents identified in the Medline database from 2011 to 2022, 23 concern 22 never-smoker longitudinal sub-cohorts.
    A link between e-cigarette experimentation at T1 and cigarette initiation at T2 is reported in sub-cohort analyses of never-smokers (AOR: 1.41 to 8.30). However, studies exclude 64.3% of T1 e-cigarette experimenters (because of dual-use) and 74.1% of T2 cigarette experimenters. With this study design, e-cigarettes contribute only to 5.3% of T2 cigarette experimentation, casting major doubt on the external validity of results and authors\' conclusions that e-cigarettes have a significant effect on the initiation of cigarettes (Gateway effect) at the population level. This sub-cohort design prohibits highlighting any Diversion effect, which is the most likely mechanism accounting for the competition between these two products.
    While nicotine abstinence remains the best medical option, over-regulation of e-cigarettes because of misinterpretation of longitudinal study results may be detrimental to public health and tobacco control.
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  • 文章类型: Journal Article
    了解婴儿和儿童的神经发育轨迹对于早期识别神经发育障碍至关重要,阐明疾病背后的神经机制,并预测发展结果。功能性近红外光谱(fNIRS)是一种婴儿友好的神经成像工具,可以监测新生儿期的脑血流动力学反应。由于其优点,fNIRS是研究神经发育轨迹的有前途的工具。尽管许多研究人员已经使用fNIRS来研究婴儿/儿童的神经发育,并报道了重要的发现,缺乏使用fNIRS追踪婴儿和儿童神经发育轨迹的综合证据.当前的系统综述总结了84项原始fNIRS研究,并显示了与年龄相关的网络整合和隔离增加的总体趋势。半球间的连通性,向左不对称,以及静息状态下相位振荡的差异。此外,通常发育中的婴儿和儿童在处理视觉时表现出更加局部化和分化的激活的发展趋势,听觉,和触觉信息,建议更成熟和专业的感官网络。在以后的生活中,儿童在处理社会听觉和语言信息时,从招募双侧听觉转变为左侧语言回路,并在执行功能任务期间显示出前额叶激活增加。发育障碍儿童的发育轨迹不同,有自闭症谱系障碍风险的婴儿在静息状态下表现出最初的过度连接,然后是连接不足;与整个童年时期通常发展中的同龄人相比,患有注意力缺陷/多动障碍的儿童在执行功能任务期间表现出更低的前额叶皮层激活。当前的系统评价支持使用fNIRS跟踪儿童的神经发育轨迹。需要更多的纵向研究来验证神经发育轨迹,并探索这些神经生物标志物在早期识别发育障碍和追踪干预效果中的应用。
    Understanding the neurodevelopmental trajectories of infants and children is essential for the early identification of neurodevelopmental disorders, elucidating the neural mechanisms underlying the disorders, and predicting developmental outcomes. Functional Near-Infrared Spectroscopy (fNIRS) is an infant-friendly neuroimaging tool that enables the monitoring of cerebral hemodynamic responses from the neonatal period. Due to its advantages, fNIRS is a promising tool for studying neurodevelopmental trajectories. Although many researchers have used fNIRS to study neural development in infants/children and have reported important findings, there is a lack of synthesized evidence for using fNIRS to track neurodevelopmental trajectories in infants and children. The current systematic review summarized 84 original fNIRS studies and showed a general trend of age-related increase in network integration and segregation, interhemispheric connectivity, leftward asymmetry, and differences in phase oscillation during resting-state. Moreover, typically developing infants and children showed a developmental trend of more localized and differentiated activation when processing visual, auditory, and tactile information, suggesting more mature and specialized sensory networks. Later in life, children switched from recruiting bilateral auditory to a left-lateralized language circuit when processing social auditory and language information and showed increased prefrontal activation during executive functioning tasks. The developmental trajectories are different in children with developmental disorders, with infants at risk for autism spectrum disorder showing initial overconnectivity followed by underconnectivity during resting-state; and children with attention-deficit/hyperactivity disorders showing lower prefrontal cortex activation during executive functioning tasks compared to their typically developing peers throughout childhood. The current systematic review supports the use of fNIRS in tracking the neurodevelopmental trajectories in children. More longitudinal studies are needed to validate the neurodevelopmental trajectories and explore the use of these neurobiomarkers for the early identification of developmental disorders and in tracking the effects of interventions.
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  • 文章类型: Journal Article
    本综合综述的目的是确定描述(a)根据症状经历及其随时间变化的症状变化模式对癌症患者进行分组的文献,以及(b)根据症状经历对癌症患者进行分组的方法。
    PubMed®,CINAHL®,和PsycINFO®在2019年1月进行了搜索。
    使用QualSyst质量评定量表对症状随时间变化的模式和方法学方法进行评估。
    11项研究符合纳入标准。影响症状模式的临床变量是多种多样的。最常见的聚类方法是潜在变量分析(73%),所有研究均使用调查分析前瞻性地收集症状数据以评估症状.
    大多数研究(91%)观察到癌症患者组中的症状经历随时间而变化。识别具有相似症状经历的患者群体有助于确定哪些患者在癌症治疗的轨迹上需要更深入的症状管理。这对改善症状和生活质量至关重要。
    The purpose of this integrative review is to identify literature describing (a) subgrouping patients with cancer based on symptom experiences and their patterns of symptom changes over time and (b) methodologies of subgrouping patients with cancer based on symptom experiences.
    PubMed®, CINAHL®, and PsycINFO® were searched through January 2019.
    Studies were appraised for patterns of symptom change over time and methodologic approach using the QualSyst quality rating scale.
    11 studies met inclusion criteria. Clinical variables that influence symptom patterns were diverse. The most common clustering method was latent variable analysis (73%), and all studies collected symptom data prospectively using survey analysis to assess symptoms.
    The majority of studies (91%) observed that the symptom experience within the group of patients with cancer changed over time. Identifying groups of patients with similar symptom experiences is useful to determine which patients need more intensive symptom management over the trajectory of cancer treatment, which is essential to improve symptoms and quality of life.
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  • 文章类型: Journal Article
    睡眠困难会增加当前和未来抑郁症的风险,但目前尚不清楚这种关系是否是因果关系。
    对70-89岁男性社区样本进行前瞻性队列研究,随访长达17年。初步评估发生在2001年至2004年之间。参与者被随访至死亡或2018年12月31日。在随后的评估波(每2-3年)中,患者健康问卷(PHQ-9)≥10,或在西澳大利亚州数据链接系统中记录的抑郁症诊断标志着抑郁症的发作。我们排除了患有普遍抑郁症的男性。根据PRISMA指南,对纵向研究进行了系统评价,以检查晚年睡眠中断与抑郁之间的关系。
    5547名老年男性中的3441人在进入研究时报告睡眠困难。当前或过去的抑郁症影响了5547名参与者中的437名。在4561名没有抑郁症的老年男性中,2693报告睡眠困难。有睡眠问题的参与者发生抑郁的风险比(HR)为1.67(95CI=1.39-2.00)。年龄的统计调整,出生地,教育,吸烟和身体虚弱并没有改变这种关联的效应大小.系统评价确定了另外14项研究,荟萃分析得出抑郁症的总体风险比为1.82(95CI=1.69-1.97),尽管现有证据的总体质量并不理想.
    睡眠中断会增加晚年患抑郁症的风险,这似乎不太可能是由于反向因果关系。有睡眠困难的老年人是预防抑郁症的干预措施的合法目标。
    Sleep difficulties increase the risk of current and future depression, but it is unclear if this relationship is causal.
    Prospective cohort study of a community sample of men aged 70-89 years followed for up to 17 years. Initial assessments occurred between 2001 and 2004. Participants were followed until death or 31 December 2018. Patient Health Questionnaire (PHQ-9) ≥ 10 at subsequent waves of assessments (every 2-3 years) or the recorded diagnosis of a depressive disorder in the Western Australian Data Linkage System marked the onset of depression during follow up. We excluded from follow up men with prevalent depression. The systematic review of longitudinal studies examining the association between disrupted sleep and depression in later life followed PRISMA guidelines.
    3441 of 5547 older men reported sleep difficulties at study entry. Current or past depression affected 437 of 5547 participants. Of the 4561 older men free of depression, 2693 reported sleep difficulties. The hazard ratio (HR) of incident depression among participants with sleep problems was 1.67 (95%CI = 1.39-2.00). Statistical adjustments for age, place of birth, education, smoking and physical frailty did not change the effect-size of this association. The systematic review identified another 14 studies, and the meta-analysis yielded an overall risk ratio of depression of 1.82 (95%CI = 1.69-1.97), although the overall quality of available evidence was sub-optimal.
    Disrupted sleep increases the risk of depression in later life and this seems unlikely to be due to reverse causality. Older adults with sleep difficulties are legitimate targets of interventions to prevent depression.
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  • 文章类型: Journal Article
    Tromsø早产干预研究(TISP)将146名早产儿童(<2000g)随机分为母婴交易计划(MITP-M,n=72)或早产对照组(n=74)。此外,对75名足月婴儿进行了随访,直到9岁。TISP在挪威北部大学医院(UNN)进行,仅包括没有先天性异常的婴儿和母亲母语为挪威语的家庭。该研究调查了MITP-M对认知和社会发展的影响,包括行为问题,家庭的生活质量和压力。到目前为止,该结果已在各种期刊上发表。本文旨在全面介绍主要发现,并讨论对临床实践和进一步研究的启示。干预组的父母在“阅读”婴儿的气质方面具有优势,在3岁,5岁和7岁时,干预组在众所周知的认知结果测试中得分明显更高.9岁时,干预组的注意力问题较少,更好的学校成绩和更好的生活质量。从第一年起,干预组的母亲和父亲报告的压力水平低于早产对照组的父母。
    The Tromsø Intervention Study on Preterms (TISP) randomized 146 preterm born children (<2000 g) either to the Mother-Infant Transaction Program-Modified (MITP-M, n = 72) or to a preterm control group (n = 74). In addition, 75 full-term babies were followed up until 9 years of age. TISP was conducted at the University Hospital Northern Norway (UNN) and only infants who did not have congenital anomalies and families where the mothers’ native language was Norwegian were included. The study investigates the effect of MITP-M on cognitive and social development including behavioral problems, quality of life and stress in the family. The results have so far been published in various journals. The aim of this article is to give a comprehensive overall presentation of the main findings and discuss implications for clinical practice and further research. Parents in the intervention group were superior in “reading” their infants’ temperament, and at 3, 5 and 7 years of age the intervention group scored significantly higher on well-known tests of cognitive outcome. At 9 years of age, the intervention group had fewer attentional problems, better school achievements and a better quality of life. From the first year onwards, mothers and fathers in the intervention group reported lower levels of stress than parents of in the preterm control group.
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