超细颗粒(<100nm)由于其毒理学潜力而日益受到关注。排放过程表明它们存在于所有环境中,包括在家里,可能会暴露在特别危险的人群中。然而,关于它们对健康影响的知识仍然有限,由于在流行病学研究中难以正确评估暴露。在这种情况下,这项研究的目的是通过研究影响这种暴露的国内活动,提供高度工业化国家室内暴露于超细颗粒的完整摘要。我们进行了系统的审查,根据使用PubMed的PRISMA指南,WebofScience和Scopus一直到2021年。我们使用标准化模板对选定的研究进行了定性和定量分析。暴露情况,测量方法,并对结果进行了分析。最后,我们对测量的浓度进行了荟萃分析,以研究家庭活动期间的暴露水平.该综述包括69项研究,分析了346种暴露情况。确定了九个主要活动组:烹饪、这是研究最多的,吸烟,使用空气清新剂,清洁,加热,个人护理,打印,自己动手活动,和其他人。这些活动涉及50多个不同的过程。根据可用的粒子数浓度,平均浓度的最高平均值与烧烤有关(14,400×103cm-3),和最低的木炉(18×103厘米-3)。峰值浓度的最高平均值是使用吹风机时的平均值(695×103cm-3),和最低的空气净化器的使用(11×103厘米-3)。提供了导致超细颗粒暴露的国内活动和相关过程的层次结构,以及家里的平均暴露浓度。然而,在现实生活条件下,需要更广泛的测量活动,以改善室内暴露于超细颗粒的评估。
Ultrafine particles (< 100 nm) are of increasing concern because of their toxicological potential. Emission processes suggest their presence in all environments, including at home, where particularly at-risk populations may be exposed. However, knowledge of their impact on health is still limited, due to difficulties in properly assessing exposure in epidemiological studies. In this context, the objective of this study was to provide a complete summary of indoor exposure to ultrafine particles in highly industrialised countries by examining the domestic activities that influence such exposure. We conducted a systematic
review, according to PRISMA guidelines using PubMed, Web of Science and Scopus up to and including 2021. We carried out a qualitative and quantitative analysis of the selected studies with a standardised template. Exposure circumstances, measurement methods, and results were analysed. Finally, a meta-analysis of the measured concentrations was performed to study exposure levels during domestic activities. The
review included 69 studies resulting in the analysis of 346 exposure situations. Nine main groups of activities were identified: cooking, which was the most studied, smoking, the use of air-fresheners, cleaning, heating, personal care, printing, do-it-yourself activities, and others. Over 50 different processes were involved in these activities. Based on available particle number concentrations, the highest average of mean concentrations was associated with grilling (14,400 × 103 cm-3), and the lowest with wood stove (18 × 103 cm-3). The highest average of peak concentrations was that for the use of hair dryers (695 × 103 cm-3), and the lowest for the use of air cleaners (11 × 103 cm-3). A hierarchy of domestic activities and related processes leading to ultrafine particle exposure is provided, along with average exposure concentrations at home. However, more extensive measurement campaigns are needed under real-life conditions to improve assessments of indoor exposure to ultrafine particles.