先前的研究已经调查了经颅直流电刺激(tDCS)对认知功能的影响。然而,由于实验设计的差异,这些研究报告了不一致的结果,测量,和刺激参数。尽管如此,缺乏关于tDCS及其对认知功能影响的荟萃分析和综述研究,包括工作记忆,抑制,灵活性,和心理理论。我们对截至2021年10月的最早可用数据发表的tDCS研究进行了系统评价和荟萃分析,包括报告tDCS对人群认知功能影响的研究。因此,本系统综述和荟萃分析旨在通过调查69篇共5545名参与者的文章,全面分析阳极和阴极型tDCS对认知功能的影响.我们的研究揭示了阳极tDCS对各种认知功能的显着影响。具体来说,我们观察到工作记忆反应时间(RT)的改善,抑制RT,灵活性RT,心理理论RT,工作记忆精度,思维准确性和灵活性准确性的理论。此外,我们的研究结果证明了值得注意的阴极tDCS效应,提高工作记忆的准确性,抑制精度,灵活性RT,灵活性准确性,心理理论RT,和心理准确性理论。值得注意的是,关于TDCS的刺激参数对认知功能的影响,结果表明,各方面存在显著差异,包括刺激的时机(在线与离线研究),人群类型(临床与健康的研究),刺激持续时间(<15分钟vs.>15分钟),电流强度(1-1.5m.Avs.>1.5m.A),刺激部位(右额叶与左额叶研究),年龄组(年轻vs.较旧的研究),以及每个认知功能方面的不同认知任务。总之,我们的结果表明,tDCS可以有效地提高认知任务绩效,为这种方法对认知改善的潜在好处提供有价值的见解。
Previous studies have investigated the effect of transcranial direct current stimulation (tDCS) on cognitive functions. However, these studies reported inconsistent results due to differences in experiment design, measurements, and stimulation parameters. Nonetheless, there is a lack of meta-analyses and
review studies on tDCS and its impact on cognitive functions, including working memory, inhibition,
flexibility, and theory of mind. We performed a systematic
review and meta-analysis of tDCS studies published from the earliest available data up to October 2021, including studies reporting the effects of tDCS on cognitive functions in human populations. Therefore, these systematic
review and meta-analysis aim to comprehensively analyze the effects of anodal and cathodal tDCS on cognitive functions by investigating 69 articles with a total of 5545 participants. Our study reveals significant anodal tDCS effects on various cognitive functions. Specifically, we observed improvements in working memory reaction time (RT), inhibition RT, flexibility RT, theory of mind RT, working memory accuracy, theory of mind accuracy and flexibility accuracy. Furthermore, our findings demonstrate noteworthy cathodal tDCS effects, enhancing working memory accuracy, inhibition accuracy, flexibility RT,
flexibility accuracy, theory of mind RT, and theory of mind accuracy. Notably, regarding the influence of stimulation parameters of tDCS on cognitive functions, the results indicated significant differences across various aspects, including the timing of stimulation (online vs. offline studies), population type (clinical vs. healthy studies), stimulation duration (< 15 min vs. > 15 min), electrical current intensities (1-1.5 m.A vs. > 1.5 m.A), stimulation sites (right frontal vs. left frontal studies), age groups (young vs. older studies), and different cognitive tasks in each cognitive functioning aspect. In conclusion, our results demonstrate that tDCS can effectively enhance cognitive task performance, offering valuable insights into the potential benefits of this method for cognitive improvement.