背景:尽管光学相干断层扫描(OCT)广泛用于角质形成细胞癌的成像,我们对基底细胞癌(BCC)的特征性OCT特征缺乏专家共识,一组经过国际审查的OCT术语来描述各种BCC亚型,和教育需求评估。
目的:为了识别OCT图像中的相关BCC特征,根据专家小组的意见提出术语,并为OCT学员确定BCC特定课程的内容。
方法:经过三轮,我们在2020年3月至9月间对BCC特征和术语进行了Delphi共识研究.在第一轮中,专家们被要求提出可由OCT辨别的BCC亚型,为每个建议的BCC子类型提供OCT图像特征,并为特定于BCC的OCT培训课程提供内容建议。如果BCC-OCT功能的一致性超过67%,该功能已被接受并包含在最终审查中。在第二轮中,专家必须重新评估一致性低于67%的特征,并对浅层BCC的十个最相关的BCCOCT图像特征进行排名,结节性BCC和浸润型和morphormBCC亚型。在最后一轮,专家收到了OCT-BCC共识清单进行最终审查,评论和确认。
结果:Delphi包括6位主要意见领袖和22位专家。在三个OCTBCC图像特征的术语上发现了共识:(i)低反射区域,(ii)超反射区域和(iii)卵形结构。Further,参与者对结节的十个最相关的图像特征进行了排名,肤浅的,浸润性和morpheapformBCC。已定义了BCCOCT成像课程的目标群体和关键组件。
结论:我们为BCC和首选术语建立了一组OCT图像特征。基于专家建议的综合课程将有助于在临床和研究环境中实施BCC的OCT成像。
BACKGROUND: Despite the widespread use of optical coherence tomography (OCT) for imaging of keratinocyte carcinoma, we lack an expert
consensus on the characteristic OCT features of basal cell carcinoma (BCC), an internationally vetted set of OCT terms to describe various BCC subtypes, and an educational needs assessment.
OBJECTIVE: To identify relevant BCC features in OCT images, propose terminology based on inputs from an expert panel and identify content for a BCC-specific curriculum for OCT trainees.
METHODS: Over three rounds, we conducted a Delphi
consensus study on BCC features and terminology between March and September 2020. In the first round, experts were asked to propose BCC subtypes discriminable by OCT, provide OCT image features for each proposed BCC subtypes and suggest content for a BCC-specific OCT training curriculum. If agreement on a BCC-OCT feature exceeded 67%, the feature was accepted and included in a final review. In the second round, experts had to re-evaluate features with less than 67% agreement and rank the ten most relevant BCC OCT image features for superficial BCC, nodular BCC and infiltrative and morpheaphorm BCC subtypes. In the final round, experts received the OCT-BCC
consensus list for a final review, comments and confirmation.
RESULTS: The Delphi included six key opinion leaders and 22 experts.
Consensus was found on terminology for three OCT BCC image features: (i) hyporeflective areas, (ii) hyperreflective areas and (iii) ovoid structures. Further, the participants ranked the ten most relevant image features for nodular, superficial, infiltrative and morpheaform BCC. The target group and the key components for a curriculum for OCT imaging of BCC have been defined.
CONCLUSIONS: We have established a set of OCT image features for BCC and preferred terminology. A comprehensive curriculum based on the expert suggestions will help implement OCT imaging of BCC in clinical and research settings.