关键词: Chinese medicine comprehensive treatment lung cancer physiological rehabilitation postoperative quality of life

Mesh : Humans Male Female Drugs, Chinese Herbal / therapeutic use Lung Neoplasms / surgery Propensity Score Middle Aged Thoracic Surgery, Video-Assisted / methods Quality of Life Prospective Studies Aged Exercise Therapy / methods Medicine, Chinese Traditional / methods Treatment Outcome Combined Modality Therapy

来  源:   DOI:10.1177/15347354241261977   PDF(Pubmed)

Abstract:
UNASSIGNED: To observe the clinical efficacy of Chinese herbal medicine combined with Liuzijue exercise on the physiological symptoms and quality of life (QoL) in postoperative patients with early-stage lung cancer.
UNASSIGNED: One hundred and eighty-three lung cancer patients who underwent video-assisted thoracoscopic surgery (VATS) were categorize into either a traditional Chinese medicine treatment group (CM) or a control group (non-traditional Chinese medicine treatment, NC), among whom 73 underwent Chinese herbal medicine and Liuzijue therapy, while 110 underwent no comprehensive treatment with traditional Chinese medicine. The propensity score matching (PSM) method with a 1:2 ratio was used to balance the baseline characteristics and evaluate the efficacy of CM in improving postoperative symptoms and QoL.
UNASSIGNED: Cough, dyspnea, chest pain, and fatigue were the most common clinical symptoms after VATS. Except for chest pain, they were all correlated with the scope of operation (P < .05). After PSM, 165 patients were identified in the matched cohort, and the covariates of gender, age, operative site, and scope of operation were balanced between the 2 groups (P > .05). In the domain of global health status, the improvement in QoL in CM was greater than that in NC (6.06 ± 15.83 vs -1.06 ± 14.68, P = .005). In terms of symptoms, improvements in cough (1.69 ± 3.15 vs 0.38 ± 2.63, P = .006), dyspnea during climbing stairs (-10.30 ± 16.82 vs -1.82 ± 17.97, P = .004), and pain (-0.76 ± 1.32 vs -0.08 ± 1.31, P = .002) in CM were better than in NC.
UNASSIGNED: Comprehensive treatment with traditional Chinese medicine (TCM) can provide therapeutic benefits in physiological rehabilitation after VATS for cancer.
摘要:
观察中药联合六子觉运动对早期肺癌术后患者生理症状及生活质量(QoL)的临床疗效。
将一百八十三名接受电视胸腔镜手术(VATS)的肺癌患者分为中药治疗组(CM)或对照组(非中药治疗,NC),其中73人接受了中草药和六子爵疗法,110未接受中医综合治疗。使用1:2比例的倾向评分匹配(PSM)方法来平衡基线特征并评估CM在改善术后症状和QoL方面的功效。
咳嗽,呼吸困难,胸痛,疲劳是VATS术后最常见的临床症状。除了胸痛,均与手术范围相关(P<0.05)。PSM之后,在匹配的队列中确定了165名患者,和性别的协变量,年龄,手术部位,两组间手术范围平衡(P>.05)。在全球健康状况领域,CM的QoL改善大于NC(6.06±15.83vs-1.06±14.68,P=.005)。就症状而言,咳嗽改善(1.69±3.15vs0.38±2.63,P=.006),爬楼梯时呼吸困难(-10.30±16.82vs-1.82±17.97,P=.004),CM的疼痛(-0.76±1.32vs-0.08±1.31,P=.002)优于NC。
中医综合治疗(TCM)可以在VATS治疗癌症后的生理康复中提供治疗益处。
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