背景:口腔鳞状细胞癌(OSCC)是全球最常见的癌症之一。OSCC诊断的延迟可能对管理和患者预后产生重大影响。口腔管理中最关键的因素之一是及时的组织病理学最终诊断。周转时间(TAT)被认为是质量性能评估的最重要组成部分。尽管计算机化取得了进步,但许多实验室仍在努力改善其TAT,运输系统,和分析技术。目的:本研究旨在评估OSCC病例的TAT,评估平均TAT周期,评估任何TAT延迟,并探讨TAT延误背后的原因。材料和方法:Saveetha牙科学院和医院的OSCC报告,钦奈,从2022年1月1日至2022年12月31日的一年内,从牙科信息档案软件(DIAS)检索,并记录了平均TAT。Further,还观察到TAT延迟的病例数,列出了他们拖延的原因。使用IBMSPSSStatisticsforWindows执行描述性统计和图形表示,V.23.0(IBM公司,Armonk,NY,美国)。进行单向ANOVA,其中显著性设定为小于0.05的p值。
结果:检索到230例OSCC病例,并纳入本研究的TAT评估。230例,161例(70%)为切口活检,69例(30%)为切除活检。只有7例(4%)切口病例和7例(10%)切除活检显示TAT延迟。TAT延迟的最常见原因是需要更深的切片和骨标本的脱钙。在161例切口病例中,只有48人(29%)接受了切除和进一步治疗。在69例切除病例中,有21例(30%)是来自其他私人机构的转介病例。12个月的总平均TAT对于切开活检为3.24±0.41天,对于切除活检为11.88±2.07天。单因素方差分析显示统计学显著的p值小于0.00001。
结论:我们的研究揭示了TAT延迟的具体挑战和改善TAT的机会。这可以导致OSCC报告的更快的TAT,进一步改善患者护理,并启用及时治疗。这项研究量化了OSCC病例的TAT,并确定了工艺改进的关键领域。这些发现可以为简化诊断工作流程的策略提供信息,减少延误,并最终提高对OSCC患者的及时护理。
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide. A delay in the diagnosis of OSCC can have a drastic impact on management and patient outcomes. One of the most crucial elements in oral management is the timely histopathological final diagnosis. Turnaround time (TAT) is regarded as the most important component of the quality performance evaluation. Many labs have struggled to improve their TATs despite advancements in computerization, transport systems, and analytical technologies. Aim: This study aimed to assess the TAT of OSCC cases, assess the mean TAT period, evaluate any TAT delays, and explore the reasons behind the TAT delays. Materials and methods: OSCC reports in Saveetha Dental College and Hospitals, Chennai, for one year from January 1, 2022, to December 31, 2022, were retrieved from the Dental Information Archival Software (DIAS), and the mean TAT was noted. Further, the number of cases with delay in TAT was also observed, and the reason for their delay was listed. Descriptive statistics and graphical representation were performed utilizing IBM SPSS Statistics for Windows, V. 23.0 (IBM Corp., Armonk, NY, USA). One-way ANOVA was performed with a significance set at a p-value less than 0.05.
RESULTS: 230 OSCC cases were retrieved and included in the TAT evaluation for this study. Among 230 cases, 161 (70%) were incisional and 69 (30%) were excisional biopsies. Only seven (4%) incisional cases and seven (10%) excisional biopsies showed a delay in TAT. The most common reason for the delay in TAT was the requirement for deeper sections and decalcification of bone specimens. Out of 161 incisional cases, only 48 (29%) have undergone excision and further treatment. Twenty-one out of 69 (30%) excisional cases were found to be referral cases from other private institutions. The overall average TAT for 12 months was 3.24 ± 0.41 days for incisional biopsies and 11.88 ± 2.07 days for excisional biopsies. One-way ANOVA revealed a statistically significant p-value of less than 0.00001.
CONCLUSIONS: Our study sheds light on specific challenges in TAT delay and opportunities for the improvement of TAT. This can result in faster TAT of OSCC reports, further improve patient care, and enable prompt treatment. This study quantified the TAT for OSCC cases and identified critical areas for process improvement. The findings can inform strategies to streamline diagnostic workflows, reduce delays, and ultimately improve the timely delivery of care to patients with OSCC.