{Reference Type}: Case Reports
{Title}: Ectomesenchymal Chondromyxoid Tumor of the Anterior Tongue: A Case Image.
{Author}: Tomo S;de Arruda JAA;Louredo BVR;Vargas PA;Simonato LE;
{Journal}: Head Neck Pathol
{Volume}: 18
{Issue}: 1
{Year}: 2024 Aug 5
暂无{DOI}: 10.1007/s12105-024-01672-z
{Abstract}: Ectomesenchymal chondromyxoid tumor (ECT) is a rare soft tissue tumor with peculiar histogenesis, exhibiting a predilection for the dorsum of the tongue. Molecular evidence suggests that it may originate from the migration of ectomesenchymal pluripotent cells from the neural crest to the tongue, where these cells may eventually proliferate and undergo myxoid and chondroid differentiation. This article illustrates a case of a 16-year-old female patient who presented with a nodule on the dorsum of her tongue, which had been present for four years. Surgical excision was performed, and histopathological analysis revealed a myxoid neoplasia composed of polygonal and spindle cells within a loose stroma containing chondroid areas. Tumor cells were positive for GFAP and S-100 proteins on immunohistochemical study, confirming the diagnosis of ECT. After a 5-year follow-up, the patient has shown no evidence of recurrence. Although rare, ECT can be diagnosed straightforwardly due to its distinctive clinical, histopathological, and immunohistochemical features. Clinicians and pathologists should become familiar with this tumor in order to avoid misdiagnosis.