PDF(Pubmed)
Abstract：
BACKGROUND: Biosurfactants are amphiphilic compounds produced by various microorganisms. Current research evaluates diverse types of biosurfactants against a range of oral pathogens.
OBJECTIVE: This systematic review aims to explore the potential of microbial-derived biosurfactants for oral applications.
METHODS: A systematic literature search was performed utilizing PubMed-MEDLINE, Scopus, and Web of Science databases with designated keywords. The results were registered in the PROSPERO database and conducted following the PRISMA checklist. Criteria for eligibility, guided by the PICOS framework, were established for both inclusion and exclusion criteria. The QUIN tool was used to assess the bias risk for in vitro dentistry studies.
RESULTS: Among the initial 357 findings, ten studies were selected for further analysis. The outcomes of this systematic review reveal that both crude and purified forms of biosurfactants exhibit antimicrobial and antibiofilm properties against various oral pathogens. Noteworthy applications of biosurfactants in oral products include mouthwash, toothpaste, and implant coating.
CONCLUSIONS: Biosurfactants have garnered considerable interest and demonstrated their potential for application in oral health. This is attributed to their surface-active properties, antiadhesive activity, biodegradability, and antimicrobial effectiveness against a variety of oral microorganisms, including bacteria and fungi.
OBJECTIVE: This systematic review aims to explore the potential of microbial-derived biosurfactants for oral applications.
METHODS: A systematic literature search was performed utilizing PubMed-MEDLINE, Scopus, and Web of Science databases with designated keywords. The results were registered in the PROSPERO database and conducted following the PRISMA checklist. Criteria for eligibility, guided by the PICOS framework, were established for both inclusion and exclusion criteria. The QUIN tool was used to assess the bias risk for in vitro dentistry studies.
RESULTS: Among the initial 357 findings, ten studies were selected for further analysis. The outcomes of this systematic review reveal that both crude and purified forms of biosurfactants exhibit antimicrobial and antibiofilm properties against various oral pathogens. Noteworthy applications of biosurfactants in oral products include mouthwash, toothpaste, and implant coating.
CONCLUSIONS: Biosurfactants have garnered considerable interest and demonstrated their potential for application in oral health. This is attributed to their surface-active properties, antiadhesive activity, biodegradability, and antimicrobial effectiveness against a variety of oral microorganisms, including bacteria and fungi.
摘要：
背景:生物表面活性剂是由各种微生物产生的两亲性化合物。当前的研究评估了针对一系列口腔病原体的各种类型的生物表面活性剂。
目的：本系统综述旨在探索微生物衍生的生物表面活性剂在口腔应用中的潜力。
方法：使用PubMed-MEDLINE进行了系统的文献检索，Scopus,和具有指定关键字的WebofScience数据库。结果已在PROSPERO数据库中注册，并按照PRISMA检查表进行。资格标准，在PICOS框架的指导下，为纳入和排除标准建立。QUIN工具用于评估体外牙科研究的偏倚风险。
结果：在最初的357个发现中，选择了10项研究进行进一步分析.本系统综述的结果表明，粗制和纯化形式的生物表面活性剂均表现出对各种口腔病原体的抗菌和抗生物膜特性。生物表面活性剂在口腔产品中的值得注意的应用包括漱口水，牙膏,和植入物涂层。
结论：生物表面活性剂已经引起了相当大的兴趣，并证明了它们在口腔健康中的应用潜力。这归因于它们的表面活性特性，抗粘附活性，生物降解性，以及对各种口腔微生物的抗菌效果，包括细菌和真菌。
目的：本系统综述旨在探索微生物衍生的生物表面活性剂在口腔应用中的潜力。
方法：使用PubMed-MEDLINE进行了系统的文献检索，Scopus,和具有指定关键字的WebofScience数据库。结果已在PROSPERO数据库中注册，并按照PRISMA检查表进行。资格标准，在PICOS框架的指导下，为纳入和排除标准建立。QUIN工具用于评估体外牙科研究的偏倚风险。
结果：在最初的357个发现中，选择了10项研究进行进一步分析.本系统综述的结果表明，粗制和纯化形式的生物表面活性剂均表现出对各种口腔病原体的抗菌和抗生物膜特性。生物表面活性剂在口腔产品中的值得注意的应用包括漱口水，牙膏,和植入物涂层。
结论：生物表面活性剂已经引起了相当大的兴趣，并证明了它们在口腔健康中的应用潜力。这归因于它们的表面活性特性，抗粘附活性，生物降解性，以及对各种口腔微生物的抗菌效果，包括细菌和真菌。
