■三维(3D)斑点追踪超声心动图(3DSTE)是无创成像的最新发展之一,可同时对心房和瓣膜环进行3D评估。3DSTE用于分析健康成人受试者的左心房(LA)体积变化与二尖瓣环(MA)尺寸和功能特性之间的相关性。
■这项回顾性队列研究共纳入297名健康受试者,其中图像质量不足是排除98例(33%)的原因。其余研究人群包括199名健康成年人,无窦性心律瓣膜反流/狭窄(平均年龄:33.5±12.7岁,104名男性,体重指数:24.7±1.2kg/m2,收缩压和舒张压:118.2±3.4mmHg和78.3±4.5mmHg,分别)。所有病例均进行了二维多普勒超声心动图和3DSTE检查。
■更大的LA体积与功能降低的更扩张的MA尺寸相关。仅在收缩期和舒张末期可以证明左心房容积升高,而LA排空分数增加仅存在于舒张末期。减少的MA部分面积变化与更大的舒张LA容积相关,较小的早期舒张LA中风量,此外,所有LA排空分数也较小。可以证明LA和MA参数之间的相关性。
■3DSTE不仅适用于腔室量化,还用于评估瓣膜环的尺寸。LA体积与MA尺寸和功能特性之间存在很强的关系。
UNASSIGNED: Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) is one of the newest development in non-invasive imaging offering simultaneous 3D evaluation of atria and valvular annuli. 3DSTE was used to analyze correlations between left atrial (LA) volume changes and mitral annular (MA) dimensions and functional properties in healthy adult subjects.
UNASSIGNED: A total of 297 healthy subjects were enrolled in this retrospective cohort study, from which insufficient quality of images was responsible for the exclusion of 98 cases (33%). The remaining study population consisted of 199 healthy adults without valvular regurgitation/stenosis in sinus rhythm (mean age: 33.5 ± 12.7 years, 104 males, body mass index: 24.7 ± 1.2 kg/ m 2 , systolic and diastolic blood pressure: 118.2 ± 3.4 mmHg and 78.3 ± 4.5 mmHg, respectively). Two-dimensional Doppler echocardiography and 3DSTE were performed in all cases.
UNASSIGNED: Larger LA volumes were associated with more dilated MA dimensions with its reduced function. Elevated LA stroke volumes could be demonstrated only in systole and end-diastole, while increased LA emptying fraction was present only in end-diastole. Reduced MA fractional area change was associated with larger diastolic LA volumes, smaller early diastolic LA stroke volume, in addition all LA emptying fractions were smaller as well. Correlations could be demonstrated between LA and MA parameters.
UNASSIGNED: 3DSTE is suitable not only for chamber quantifications, but also for the assessment of valvular annular dimensions. Strong relationship exists between LA volumes and MA dimensions and functional properties.