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Abstract：
There has been increasing evidence supporting the importance of left atrial (LA) functional analysis and measurement in various physiologic and pathologic cardiovascular conditions due to its high diagnostic and prognostic values. Assessment of LA strain (LAS) has emerged as an early marker of subclinical LA dysfunction. Using speckle-tracking echocardiography, LAS can be measured in all phases of LA function (reservoir, conduit, and booster pump). In valvular heart disease (VHD), surgical and nonsurgical interventions should be performed before irreversible left ventricular (LV) and/or LA myocardial dysfunction. The current guidelines recommended using LV strain as a parameter for early detection and timely intervention. Currently, many published data have shown the diagnostic and prognostic values of LAS in VHD, which is encouraging to integrate LAS during echo assessment. In this review, we aim to collect the current data about the clinical utility of LAS changes in risk stratification, predicting outcome, and guiding the time of intervention in VHD. The review summarized these data according to the type of valve pathologies.
摘要：
越来越多的证据支持左心房（LA）功能分析和测量在各种生理和病理心血管疾病中的重要性，因为它具有很高的诊断和预后价值。LA菌株（LAS）的评估已成为亚临床LA功能障碍的早期标志物。使用斑点追踪超声心动图，LAS可以在LA功能的所有阶段进行测量(储层，导管,和增压泵)。在瓣膜性心脏病（VHD）中，在不可逆的左心室(LV)和/或LA心肌功能障碍前,应进行手术和非手术干预.目前的指南建议使用LV菌株作为早期检测和及时干预的参数。目前,许多已发表的数据显示了LAS在VHD中的诊断和预后价值，这令人鼓舞的是在回声评估期间整合LAS。在这次审查中,我们的目标是收集有关LAS变化在风险分层中的临床效用的当前数据，预测结果，并指导VHD的干预时间。该综述根据瓣膜病变的类型总结了这些数据。
