氧化应激和炎症主要导致衰老和年龄相关的病症,包括皮肤衰老。天然化妆品形式的天然产品的潜力,药妆,和营养移植,然而,没有得到充分利用。这次审查,因此,批判性地分析了天然产品在炎症相关的皮肤老化疾病中的潜在作用,由于消费者对有效的关注和需求不断增加,安全,自然,可持续,和宗教允许的合成产品的替代品。这些信息和数据是从各种资源和文献数据库中整理的,如PubMed、科学直接,威利,Springer,泰勒和弗朗西斯,Scopus,Inflibnet,Google,和谷歌学者使用相关关键词和医学主题词(MeSH)。还阐明了绿色萃取溶剂作为有希望的替代品的作用。生物利用度的潜在增强,稳定性,还提供了使用不同递送系统的生物活性物质的溶解度和受控释放曲线。当前潜在的全球市场价值,动机,司机,趋势,挑战,清真,以及药妆品和营养品的其他监管认证也同样进行了讨论。采用建议的提取和递送系统将增强稳定性,生物利用度,和生物活性物质的靶向递送。
Oxidative stress and inflammation mostly contribute to aging and age-related conditions including skin aging. The potential of natural products in the form of naturally-derived cosmetics, cosmeceuticals, and nutricosmetics have, however, not been fully harnessed. This review, thus, critically analyzes the potential roles of natural products in inflammation-related skin aging diseases due to the increasing consumers\' concerns and demands for efficacious, safe, natural, sustainable, and religiously permitted alternatives to synthetic products. The information and data were collated from various resources and literature databases such as PubMed, Science Direct, Wiley, Springer, Taylor and Francis, Scopus, Inflibnet, Google, and Google Scholar using relevant keywords and Medical Subject Headings (MeSH). The role of green extraction solvents as promising alternatives is also elucidated. The potential enhancements of the bioavailability, stability, solubility and controlled release profile of the bioactives using different delivery systems are also presented. The current potential global market value, motivators, drivers, trends, challenges, halal, and other regulatory certifications for cosmeceuticals and nutricosmetics are equally discussed. The adoption of the suggested extractions and delivery systems would enhance the stability, bioavailability, and target delivery of the bioactives.